Published in J Physiol on September 01, 1976
Local anaesthetics transiently block currents through single acetylcholine-receptor channels. J Physiol (1978) 10.05
The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture. J Physiol (1988) 4.91
Voltage jump analysis of procaine action at frog end-plate. J Physiol (1977) 4.27
The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anaesthetics. J Physiol (1983) 3.76
The actions of tubocurarine at the frog neuromuscular junction. J Physiol (1979) 3.69
Interaction of permeant ions with channels activated by acetylcholine in Aplysia neurones. J Physiol (1979) 2.80
Decamethonium both opens and blocks endplate channels. Proc Natl Acad Sci U S A (1978) 2.29
The mode of action of antagonists of the excitatory response to acetylcholine in Aplysia neurones. J Physiol (1978) 2.26
Determination of dose-response curves by quantitative ionophoresis at the frog neuromuscular junction. J Physiol (1978) 2.12
Substance P reduces acetylcholine-induced currents in isolated bovine chromaffin cells. J Physiol (1984) 2.09
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The channel-blocking action of methonium compounds on rat submandibular ganglion cells. Br J Pharmacol (1984) 1.60
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Octanol reduces end-plate channel lifetime. J Physiol (1978) 1.48
Endplate channel block by guanidine derivatives. J Gen Physiol (1981) 1.46
The action of ganglionic blocking drugs on the synaptic responses of rat submandibular ganglion cells. Br J Pharmacol (1982) 1.46
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Quinacrine (mepacrine) action at frog end-plate. J Physiol (1980) 1.42
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Single channels activated by acetylcholine in rat superior cervical ganglion. J Physiol (1987) 1.09
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Comparison of desensitization and time-dependent block of the acetylcholine receptor responses by chlorpromazine, cytochalasin B, triton X-100 and other agents. Br J Pharmacol (1980) 0.97
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Some effects of procaine at the toad end-plate are not consistent with a simple channel-blocking model. J Physiol (1984) 0.96
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Cocaine and phencyclidine inhibition of the acetylcholine receptor: analysis of the mechanisms of action based on measurements of ion flux in the millisecond-to-minute time region. Proc Natl Acad Sci U S A (1982) 0.95
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An attempt to distinguish between the actions of neuromuscular blocking drugs on the acetylcholine receptor and on its associated ionic channel. Proc Natl Acad Sci U S A (1980) 0.85
The mechanism by which procaine inhibits catecholamine secretion from bovine chromaffin cells. Br J Pharmacol (1992) 0.85
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Relative potencies for barbiturate binding to the Torpedo acetylcholine receptor. Br J Pharmacol (1990) 0.82
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Effects of drugs on acetylcholine-activated ionic channels of internally perfused chick myoballs. J Physiol (1983) 0.78
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Voltage-dependent drug blockade of L-glutamate activated channels of the crayfish. J Physiol (1983) 0.76
Hydrostatic pressure modifies the action of octanol and atropine on frog endplate conductance. Br J Pharmacol (1984) 0.76
A kinetic analysis of the endplate ion channel blocking action of disopyramide and its optical isomers. Br J Pharmacol (1987) 0.76
A new class of potent centrally acting muscle relaxants: pharmacology of oxazolidinones in rat decerebrate rigidity. Br J Pharmacol (1986) 0.76
The channel-blocking action of methonium compounds on rat submandibular ganglion cells. 1983. Br J Pharmacol (1997) 0.75
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The rate of action of tetrodotoxin on myelinated nerve fibres of Xenopus laevis and Rana esculenta. J Physiol (1973) 2.04
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Voltage dependence of agonist responses at voltage-clamped frog endplates. Pflugers Arch (1976) 1.60
Mechanism of blockade of neuromuscular transmission by pentobarbital. J Pharmacol Exp Ther (1975) 1.47
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M-currents and other potassium currents in bullfrog sympathetic neurones. J Physiol (1982) 4.50
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An analysis of the dose-response curve at voltage-clamped frog-endplates. Pflugers Arch (1975) 2.12
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