Published in Mol Biol Cell on August 01, 1999
Physical interaction between RRS1-R, a protein conferring resistance to bacterial wilt, and PopP2, a type III effector targeted to the plant nucleus. Proc Natl Acad Sci U S A (2003) 3.52
Large-scale identification of yeast integral membrane protein interactions. Proc Natl Acad Sci U S A (2005) 2.03
Yeast two-hybrid, a powerful tool for systems biology. Int J Mol Sci (2009) 1.59
Cdc48/p97 and Shp1/p47 regulate autophagosome biogenesis in concert with ubiquitin-like Atg8. J Cell Biol (2010) 1.50
Srb7p is a physical and physiological target of Tup1p. EMBO J (2000) 1.45
Protein-protein interactions between sucrose transporters of different affinities colocalized in the same enucleate sieve element. Plant Cell (2002) 1.45
The Arabidopsis P4-ATPase ALA3 localizes to the golgi and requires a beta-subunit to function in lipid translocation and secretory vesicle formation. Plant Cell (2008) 1.23
A new screen for protein interactions reveals that the Saccharomyces cerevisiae high mobility group proteins Nhp6A/B are involved in the regulation of the GAL1 promoter. Proc Natl Acad Sci U S A (2000) 1.21
Topological and mutational analysis of Saccharomyces cerevisiae Ste14p, founding member of the isoprenylcysteine carboxyl methyltransferase family. Mol Biol Cell (2001) 1.20
Identification of novel ErbB3-interacting factors using the split-ubiquitin membrane yeast two-hybrid system. Genome Res (2003) 1.19
Interactions between co-expressed Arabidopsis sucrose transporters in the split-ubiquitin system. BMC Biochem (2003) 1.17
Recognition of a subset of signal sequences by Ssh1p, a Sec61p-related protein in the membrane of endoplasmic reticulum of yeast Saccharomyces cerevisiae. Mol Biol Cell (2002) 1.14
Diversity in genetic in vivo methods for protein-protein interaction studies: from the yeast two-hybrid system to the mammalian split-luciferase system. Microbiol Mol Biol Rev (2012) 1.11
Cell growth-dependent coordination of lipid signaling and glycosylation is mediated by interactions between Sac1p and Dpm1p. J Cell Biol (2005) 1.08
The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B. Mol Cell Biol (2004) 0.92
Sec62p, a component of the endoplasmic reticulum protein translocation machinery, contains multiple binding sites for the Sec-complex. Mol Biol Cell (2000) 0.90
Association of cytochrome b5 with ETR1 ethylene receptor signaling through RTE1 in Arabidopsis. Plant J (2014) 0.87
Arabidopsis Bax inhibitor-1 promotes sphingolipid synthesis during cold stress by interacting with ceramide-modifying enzymes. Planta (2014) 0.87
Phosphatidylethanolamine deficiency disrupts α-synuclein homeostasis in yeast and worm models of Parkinson disease. Proc Natl Acad Sci U S A (2014) 0.86
TOR-induced resistance to toxic adenosine analogs in Leishmania brought about by the internalization and degradation of the adenosine permease. Exp Cell Res (2007) 0.84
Identification of protein interactions involved in cellular signaling. Mol Cell Proteomics (2013) 0.84
A new method for the selection of protein interactions in mammalian cells. Biochem J (2000) 0.83
Techniques for the Analysis of Protein-Protein Interactions in Vivo. Plant Physiol (2016) 0.82
Preferential targeting of a signal recognition particle-dependent precursor to the Ssh1p translocon in yeast. J Biol Chem (2011) 0.82
An optimized split-ubiquitin cDNA-library screening system to identify novel interactors of the human Frizzled 1 receptor. Nucleic Acids Res (2008) 0.82
Regulation of vacuolar H+-ATPase activity by the Cdc42 effector Ste20 in Saccharomyces cerevisiae. Eukaryot Cell (2012) 0.81
Ssh4, Rcr2 and Rcr1 affect plasma membrane transporter activity in Saccharomyces cerevisiae. Genetics (2007) 0.81
Signaling of human frizzled receptors to the mating pathway in yeast. PLoS One (2007) 0.80
Functional genomics in the study of yeast cell polarity: moving in the right direction. Philos Trans R Soc Lond B Biol Sci (2013) 0.80
The Cdc42 effectors Ste20, Cla4, and Skm1 down-regulate the expression of genes involved in sterol uptake by a mitogen-activated protein kinase-independent pathway. Mol Biol Cell (2009) 0.79
PI3P binding by Atg21 organises Atg8 lipidation. EMBO J (2015) 0.79
A fluorescent reporter for mapping cellular protein-protein interactions in time and space. Mol Syst Biol (2013) 0.78
Plant sphingolipid fatty acid 2-hydroxylases have unique characters unlike their animal and fungus counterparts. Plant Signal Behav (2012) 0.78
Analysis of Sec61p and Ssh1p interactions in the ER membrane using the split-ubiquitin system. BMC Cell Biol (2013) 0.77
The TATA-binding protein is not an essential target of the transcriptional activators Gal4p and Gcn4p in Saccharomyces cerevisiae. Biochem J (2003) 0.77
Phenotypes on demand via switchable target protein degradation in multicellular organisms. Nat Commun (2016) 0.76
A Split-Ubiquitin Based Strategy Selecting for Protein Complex-Interfering Mutations. G3 (Bethesda) (2016) 0.75
A Novel GLP1 Receptor Interacting Protein ATP6ap2 Regulates Insulin Secretion in Pancreatic Beta Cells. J Biol Chem (2015) 0.75
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics (1989) 105.30
Mechanisms of intracellular protein transport. Nature (1994) 13.54
A new efficient gene disruption cassette for repeated use in budding yeast. Nucleic Acids Res (1996) 11.05
Protein prenylation: molecular mechanisms and functional consequences. Annu Rev Biochem (1996) 8.08
Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane. Annu Rev Cell Biol (1994) 5.54
Split ubiquitin as a sensor of protein interactions in vivo. Proc Natl Acad Sci U S A (1994) 5.16
Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions. Proc Natl Acad Sci U S A (1996) 4.70
The recognition component of the N-end rule pathway. EMBO J (1990) 4.55
Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation. Nature (1997) 4.40
Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport. EMBO J (1993) 4.27
Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes. Annu Rev Biochem (1996) 4.25
A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole. J Cell Biol (1997) 4.16
Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast. J Cell Biol (1989) 4.13
Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex. Science (1997) 3.95
SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex. J Cell Biol (1992) 3.79
A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation. Cell (1992) 3.78
Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae. Cell (1993) 3.67
The a-factor pheromone of Saccharomyces cerevisiae is essential for mating. Mol Cell Biol (1988) 3.62
A genetic system based on split-ubiquitin for the analysis of interactions between membrane proteins in vivo. Proc Natl Acad Sci U S A (1998) 3.62
Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p. Cell (1995) 3.46
Signal sequences specify the targeting route to the endoplasmic reticulum membrane. J Cell Biol (1996) 3.33
Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex. Nature (1991) 3.21
Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae. EMBO J (1996) 3.09
A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome. J Cell Biol (1993) 2.65
Topology and functional domains of Sec63p, an endoplasmic reticulum membrane protein required for secretory protein translocation. Mol Cell Biol (1992) 2.51
An essential yeast gene encoding a homolog of ubiquitin-activating enzyme. J Biol Chem (1995) 2.50
Structural and functional dissection of Sec62p, a membrane-bound component of the yeast endoplasmic reticulum protein import machinery. Mol Cell Biol (1990) 2.36
The N-end rule pathway of protein degradation. Genes Cells (1997) 2.35
Localization of Sed5, a putative vesicle targeting molecule, to the cis-Golgi network involves both its transmembrane and cytoplasmic domains. J Cell Biol (1994) 2.32
The dynamics of golgi protein traffic visualized in living yeast cells. Mol Biol Cell (1998) 2.29
The BOS1 gene encodes an essential 27-kD putative membrane protein that is required for vesicular transport from the ER to the Golgi complex in yeast. J Cell Biol (1991) 2.09
Vam3p, a new member of syntaxin related protein, is required for vacuolar assembly in the yeast Saccharomyces cerevisiae. J Cell Sci (1997) 2.05
A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae. EMBO J (1996) 1.93
Determination of the transmembrane topology of yeast Sec61p, an essential component of the endoplasmic reticulum translocation complex. J Biol Chem (1996) 1.81
The mitochondrial receptor complex: a central role of MOM22 in mediating preprotein transfer from receptors to the general insertion pore. Cell (1993) 1.67
Membrane insertion of uracil permease, a polytopic yeast plasma membrane protein. Mol Cell Biol (1991) 1.65
Identification of a C-terminal protein carboxyl methyltransferase in rat liver membranes utilizing a synthetic farnesyl cysteine-containing peptide substrate. J Biol Chem (1990) 1.51
Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export. Mol Cell Biol (1994) 1.43
ER membrane protein complex required for nuclear fusion. J Cell Biol (1996) 1.43
The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane. Mol Biol Cell (1998) 1.36
The intermembrane space domain of mitochondrial Tom22 functions as a trans binding site for preproteins with N-terminal targeting sequences. Mol Cell Biol (1997) 1.33
Primary structure of the uracil transport protein of Saccharomyces cerevisiae. Eur J Biochem (1988) 1.31
Detection of transient in vivo interactions between substrate and transporter during protein translocation into the endoplasmic reticulum. Mol Biol Cell (1999) 1.27
Just follow the acid chain. Nature (1997) 1.23
Involvement of mitochondrial contact sites in the subcellular compartmentalization of phospholipid biosynthetic enzymes. J Biol Chem (1993) 1.13
Recycling of the yeast v-SNARE Sec22p involves COPI-proteins and the ER transmembrane proteins Ufe1p and Sec20p. J Cell Sci (1998) 1.08
Pth1/Vam3p is the syntaxin homolog at the vacuolar membrane of Saccharomyces cerevisiae required for the delivery of vacuolar hydrolases. Genetics (1998) 1.07
A yeast genetic system for selecting small molecule inhibitors of protein-protein interactions in nanodroplets. Proc Natl Acad Sci U S A (1997) 1.04
Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature (1995) 7.40
Defective B cell development and function in Btk-deficient mice. Immunity (1995) 4.20
Role of SUMO-1-modified PML in nuclear body formation. Blood (2000) 4.05
Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. J Exp Med (1996) 3.86
A genetic system based on split-ubiquitin for the analysis of interactions between membrane proteins in vivo. Proc Natl Acad Sci U S A (1998) 3.62
Complete DNA sequence of yeast chromosome XI. Nature (1994) 3.51
The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells. J Cell Biol (2001) 3.43
Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism. Cell (1992) 3.42
Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J (1994) 3.27
Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res (1992) 2.89
Cytochrome c oxidase assembly in primates is sensitive to small evolutionary variations in amino acid sequence. Mol Biol Evol (2000) 2.19
PIAS/SUMO: new partners in transcriptional regulation. Cell Mol Life Sci (2003) 2.15
The human Rad52 protein exists as a heptameric ring. Curr Biol (2000) 2.09
Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulation. J Exp Med (1997) 2.06
Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex. Mol Biol Cell (1995) 2.04
Complete DNA sequence of yeast chromosome II. EMBO J (1994) 1.97
Recovery from Wernicke's aphasia: a positron emission tomographic study. Ann Neurol (1995) 1.86
Antibodies to flagellin indicate reactivity to bacterial antigens in IBS patients. Neurogastroenterol Motil (2008) 1.80
Laufband therapy based on 'rules of spinal locomotion' is effective in spinal cord injured persons. Eur J Neurosci (1995) 1.72
Thioredoxin reductase two modes of catalysis have evolved. Eur J Biochem (2000) 1.70
Natural variation in the response of Caenorhabditis elegans towards Bacillus thuringiensis. Parasitology (2004) 1.70
Laufband locomotion with body weight support improved walking in persons with severe spinal cord injuries. Paraplegia (1992) 1.66
Thioredoxin reductase as a pathophysiological factor and drug target. Eur J Biochem (2000) 1.63
Effects of staff training on the care of mechanically ventilated patients: a prospective cohort study. Br J Anaesth (2009) 1.63
Beam hardening artefacts occur in dental implant scans with the NewTom cone beam CT but not with the dental 4-row multidetector CT. Dentomaxillofac Radiol (2007) 1.58
Phosducin is a protein kinase A-regulated G-protein regulator. Nature (1992) 1.55
Internalin B is essential for adhesion and mediates the invasion of Listeria monocytogenes into human endothelial cells. Mol Microbiol (1998) 1.54
Recruitment of spinal motor pools during voluntary movements versus stepping after human spinal cord injury. J Neurotrauma (2002) 1.51
Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes. Curr Biol (2000) 1.45
Mobilization and collection of allogeneic peripheral blood progenitor cells for transplantation. Bone Marrow Transplant (1998) 1.43
Using ubiquitin to follow the metabolic fate of a protein. Proc Natl Acad Sci U S A (1996) 1.43
Human herpesvirus 6 DNA in exanthematous skin in BMT patient. Lancet (1994) 1.40
MUC1: the polymorphic appearance of a human mucin. Glycobiology (2000) 1.39
Covalent modification of the transcriptional repressor tramtrack by the ubiquitin-related protein Smt3 in Drosophila flies. Mol Cell Biol (2000) 1.36
Brain representation of active and passive movements. Neuroimage (1996) 1.36
Characterization of KIF1C, a new kinesin-like protein involved in vesicle transport from the Golgi apparatus to the endoplasmic reticulum. J Biol Chem (1998) 1.35
Regulation of Pax3 transcriptional activity by SUMO-1-modified PML. Oncogene (2001) 1.35
A soluble form of TRAP (CD40 ligand) is rapidly released after T cell activation. Eur J Immunol (1995) 1.29
The signal that sorts yeast cytochrome b2 to the mitochondrial intermembrane space contains three distinct functional regions. EMBO J (1993) 1.29
Initial results in the assessment of multiple myeloma using 18F-FDG PET. Eur J Nucl Med Mol Imaging (2002) 1.28
Maintenance of locomotor abilities following Laufband (treadmill) therapy in para- and tetraplegic persons: follow-up studies. Spinal Cord (1998) 1.27
Detection of transient in vivo interactions between substrate and transporter during protein translocation into the endoplasmic reticulum. Mol Biol Cell (1999) 1.27
Arm training induced brain plasticity in stroke studied with serial positron emission tomography. Neuroimage (2001) 1.26
The submembranous location of p11 and its interaction with the p36 substrate of pp60 src kinase in situ. Exp Cell Res (1988) 1.26
Inter-domain cross-linking and molecular modelling of the hairpin ribozyme. J Mol Biol (1997) 1.25
Tetrabrachion: a filamentous archaebacterial surface protein assembly of unusual structure and extreme stability. J Mol Biol (1995) 1.24
Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection. Eur J Immunol (1994) 1.23
Cardio-specific long-term gene expression in a porcine model after selective pressure-regulated retroinfusion of adeno-associated viral (AAV) vectors. Gene Ther (2007) 1.23
Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking. J Mol Biol (2001) 1.22
Subunit stoichiometry and three-dimensional arrangement in proteasomes from Thermoplasma acidophilum. EMBO J (1992) 1.22
Evolution of functional reorganization in hemiplegic stroke: a serial positron emission tomographic activation study. Ann Neurol (1999) 1.21
A new screen for protein interactions reveals that the Saccharomyces cerevisiae high mobility group proteins Nhp6A/B are involved in the regulation of the GAL1 promoter. Proc Natl Acad Sci U S A (2000) 1.21
Binding sites for calcium, lipid and p11 on p36, the substrate of retroviral tyrosine-specific protein kinases. FEBS Lett (1986) 1.20
1-N-naphthylphthalamic acid and 2,3,5-triiodobenzoic acid : In-vitro binding to particulate cell fractions and action on auxin transport in corn coleoptiles. Planta (1973) 1.19
Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice. Oncogene (2010) 1.19
The rod domain of NF-L determines neurofilament architecture, whereas the end domains specify filament assembly and network formation. J Cell Biol (1993) 1.16
Plasmodium falciparum-infected red blood cells depend on a functional glutathione de novo synthesis attributable to an enhanced loss of glutathione. Biochem J (2000) 1.16
[What visual information does the automobile driver need for safe driving in street traffic?]. Ophthalmologe (1994) 1.16
Secretion of human meprin from intestinal epithelial cells depends on differential expression of the alpha and beta subunits. Eur J Biochem (1999) 1.15
Protein-protein recognition via short amphiphilic helices; a mutational analysis of the binding site of annexin II for p11. EMBO J (1990) 1.13
Ubiquitous soluble Mg(2+)-ATPase complex. A structural study. J Mol Biol (1992) 1.13
Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates. Eur J Immunol (1996) 1.12
The malaria parasite Plasmodium falciparum possesses a functional thioredoxin system. Mol Biochem Parasitol (2001) 1.12
Mechanisms underlying the anti-inflammatory actions of boswellic acid derivatives in experimental colitis. Am J Physiol Gastrointest Liver Physiol (2006) 1.12
Transcriptional regulation of genes encoding the selenium-free [NiFe]-hydrogenases in the archaeon Methanococcus voltae involves positive and negative control elements. Genetics (1999) 1.12
Changes in peptidergic innervation in chronic pancreatitis. Pancreas (1992) 1.12
The [NiFe] hydrogenases of Methanococcus voltae: genes, enzymes and regulation. Arch Microbiol (1997) 1.11
Simultaneous overexpression of enzymes of the lower part of glycolysis can enhance the fermentative capacity of Saccharomyces cerevisiae. Yeast (2000) 1.10
The amino acid sequence of protein II and its phosphorylation site for protein kinase C; the domain structure Ca2+-modulated lipid binding proteins. EMBO J (1987) 1.10
Functional significance of symmetrical versus asymmetrical GroEL-GroES chaperonin complexes. Science (1995) 1.07
Reorganization of sensory and motor systems in hemiplegic stroke patients. A positron emission tomography study. Stroke (1999) 1.07
Laufband (treadmill) therapy in incomplete paraplegia and tetraplegia. J Neurotrauma (1999) 1.06
Purification, structural analysis, and function of natural ATAC, a cytokine secreted by CD8(+) T cells. J Biol Chem (1997) 1.06
The bisphosphonate ibandronate improves implant integration in osteopenic ovariectomized rats. Bone (2005) 1.06
Head-to-head comparison of N-terminal pro-brain natriuretic peptide, brain natriuretic peptide and N-terminal pro-atrial natriuretic peptide in diagnosing left ventricular dysfunction. Clin Chim Acta (2001) 1.06
Idiotypic networks and nature of molecular mimicry: an overview. Methods Enzymol (1989) 1.05
Investigation of two yeast genes encoding putative isoenzymes of phosphoglycerate mutase. Yeast (1998) 1.05
Cloning and expression of cDNAs encoding alpha1,3-fucosyltransferase homologues from Arabidopsis thaliana. Biochim Biophys Acta (2001) 1.04
Simultaneous contralateral testicular metastasis from a renal clear cell carcinoma. Scand J Urol Nephrol (1999) 1.04
Functionally distinct serine phosphorylation sites of p36, the cellular substrate of retroviral protein kinase; differential inhibition of reassociation with p11. EMBO J (1986) 1.04
On the timing of soft-tissue reconstruction for open fractures of the lower leg. Arch Orthop Trauma Surg (1999) 1.03
Is the polymerase chain reaction or cure of Helicobacter pylori infection of help in the differential diagnosis of early gastric mucosa-associated lymphatic tissue lymphoma? J Clin Oncol (1997) 1.03
The thermosome of Thermoplasma acidophilum and its relationship to the eukaryotic chaperonin TRiC. Eur J Biochem (1995) 1.03
Towards many colors in FISH on 3D-preserved interphase nuclei. Cytogenet Genome Res (2006) 1.03
Gene expression patterns of epithelial cells modulated by pathogenicity factors of Yersinia enterocolitica. Cell Microbiol (2004) 1.03
Stimulation of chemiluminescence and resistance against aerogenic influenza virus infection by synthetic muramyl dipeptide combined with trehalose dimycolate. Infect Immun (1984) 1.02
Catalyst-nanostructure interaction in the growth of 1-D ZnO nanostructures. J Phys Chem B (2006) 1.01
Cell differentiation and matrix gene expression in mesenchymal chondrosarcomas. Am J Pathol (2000) 1.00
Characterization and molecular cloning of a Cu/Zn superoxide dismutase from the human parasite Onchocerca volvulus. Infect Immun (1991) 1.00
EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis. Oncogene (2011) 1.00
Molecular anatomy of the neuro-immune connection. Int J Neurosci (1991) 1.00
Deceptive imprinting in the immune response against HIV-1. Immunol Today (1994) 1.00
Discovery and optimization of a novel class of orally active nonpeptidic endothelin-A receptor antagonists. J Med Chem (1996) 1.00
Side differences of knee joint cartilage volume, thickness, and surface area, and correlation with lower limb dominance--an MRI-based study. Osteoarthritis Cartilage (2002) 1.00
The putative gamma-glutamylcysteine synthetase from Plasmodium falciparum contains large insertions and a variable tandem repeat. Mol Biochem Parasitol (1999) 1.00
Hemozoin differentially modulates the production of interleukin 6 and tumor necrosis factor in murine malaria. Eur Cytokine Netw (1995) 0.99
Comparative evaluation of the effects of tetracycline, rolitetracycline and doxycycline on some blood parameters related to liver function. Arzneimittelforschung (1982) 0.98
Effect of systemic pH on pHi and lactic acid generation in exhaustive forearm exercise. Am J Physiol (1988) 0.98