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K Ohuchi

Author PubWeight™ 91.57‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mice lacking histidine decarboxylase exhibit abnormal mast cells. FEBS Lett 2001 2.15
2 Intraepithelial CD8+ T-cell-count becomes a prognostic factor after a longer follow-up period in human colorectal carcinoma: possible association with suppression of micrometastasis. Br J Cancer 2004 1.80
3 Determination of cyclooxygenase products and prostaglandin metabolites using high-pressure liquid chromatography and radioimmunoassay. Anal Biochem 1979 1.72
4 Stimulation of prostaglandin synthesis by tumor-promoting phorbol-12, 13-diesters in canine kidney (MDCK) cells. Cycloheximide inhibits the stimulated prostaglandin synthesis, deacylation of lipids, and morphological changes. J Biol Chem 1978 1.28
5 Glycyrrhizin inhibits prostaglandin E2 production by activated peritoneal macrophages from rats. Prostaglandins Med 1981 1.21
6 The content of prostaglandin E and prostaglandin F2alpha in the exudate of carrageenin granuloma of rats. Biochim Biophys Acta 1976 1.14
7 Induction of an allergic air-pouch inflammation in rats. Int Arch Allergy Appl Immunol 1982 1.13
8 Retinoids as well as tumour promoters enhance deacylation of cellular lipids and prostaglandin production in MDCK cells. Nature 1978 1.11
9 Cyclooxygenase-2-mediated angiogenesis in carrageenin-induced granulation tissue in rats. J Pharmacol Exp Ther 2000 1.10
10 Novel roles of CpG oligodeoxynucleotides as a leader for the sampling and presentation of CpG-tagged antigen by dendritic cells. J Immunol 2001 1.09
11 Antiinflammatory actions of ephedrines in acute inflammations1. Planta Med 1985 1.04
12 Mechanisms underlying the attenuation of endothelium-dependent vasodilatation in the mesenteric arterial bed of the streptozotocin-induced diabetic rat. Br J Pharmacol 2000 1.03
13 Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors. Br J Pharmacol 2001 1.03
14 Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum. Planta Med 2001 1.00
15 Tumor promoting phorbol diesters stimulate release of radioactivity from [3H]-arachidonic acid labeled- but not [14C]linoleic acid labeled-cells. Indomethacin inhibits the stimulated release from [3H] arachidonate labeled cells. Prostaglandins Med 1978 0.99
16 A possible role of arachidonate metabolism in allergic air pouch inflammation in rats. Anti-inflammatory effect of indomethacin and dexamethasone and the level of prostaglandin E2 in the exudate. Int Arch Allergy Appl Immunol 1982 0.99
17 Role of endogenous histamine in postanaphylactic phase of allergic inflammation in rats. J Pharmacol Exp Ther 1987 0.99
18 Stimulation of arachidonic acid metabolism in rat peritoneal macrophages by thapsigargin, a non-(12-O-tetradecanoylphorbol-13-acetate) (TPA)-type tumor promoter. J Cancer Res Clin Oncol 1987 0.97
19 Stimulation of prostaglandin E2 production by 12-O-tetradecanoylphorbol 13-acetate (TPA)-type and non-TPA-type tumor promoters in macrophages and its inhibition by cycloheximide. Biochim Biophys Acta 1985 0.95
20 Stimulation of neutrophil adherence to vascular endothelial cells by histamine and thrombin and its inhibition by PAF antagonists and dexamethasone. Br J Pharmacol 1991 0.95
21 Comparative study between steroidal and nonsteroidal anti-inflammatory drugs on the mode of their actions on vascular permeability in rat carrageenin-air-pouch inflammation. J Pharmacobiodyn 1980 0.94
22 Analysis of histamine-producing cells at the late phase of allergic inflammation in rats. Immunology 2000 0.93
23 Induction of neutrophil chemotactic factor production by staurosporine in rat peritoneal neutrophils. Br J Pharmacol 1997 0.92
24 Pharmacological analysis of the vascular permeability response in the anaphylactic phase of allergic inflammation in rats. Eur J Pharmacol 1985 0.92
25 Protocollagen proline hydroxylase in isolated rat liver cells. Biochim Biophys Acta 1972 0.92
26 Induction of neutrophil infiltration by rat chemotactic cytokine (CINC) and its inhibition by dexamethasone in rats. Inflammation 1992 0.92
27 Morphological study of amyloid fibrils and preamyloid deposits in the brain with Alzheimer's disease. Acta Neuropathol 1992 0.92
28 Reduction by dexamethasone of chemotactic activity in inflammatory exudates. Eur J Pharmacol 1984 0.92
29 Arachidonate metabolites in acute and chronic allergic air pouch inflammation in rats and the anti-inflammatory effects of indomethacin and dexamethasone. Int Arch Allergy Appl Immunol 1984 0.91
30 Downward regulation of neutrophil infiltration by endogenous histamine without affecting vascular permeability responses in air-pouch-type carrageenin inflammation in rats. Inflammation 1991 0.90
31 Delayed-type hypersensitivity as revealed on the footpads of mice to azobenzenearsonate-acetyl bovine serum albumin. Int Arch Allergy Appl Immunol 1981 0.90
32 Vascular permeability responses and the role of prostaglandin E2 in an experimental allergic inflammation of air pouch type in rats. Br J Pharmacol 1986 0.89
33 Possible participation of intracellular platelet-activating factor in tumor necrosis factor-alpha production by rat peritoneal macrophages. Eur J Pharmacol 1999 0.89
34 Inhibition by dexamethasone of antigen-induced c-Jun N-terminal kinase activation in rat basophilic leukemia cells. J Immunol 1998 0.89
35 Generation of rat eosinophils by recombinant rat interleukin-5 in vitro and in vivo. Biochim Biophys Acta 2000 0.88
36 Orosomucoid as the accelerator of hepatic fibrosis. Br J Exp Pathol 1986 0.88
37 Effects of glucocorticoids on apoptosis of infiltrated eosinophils and neutrophils in rats. Eur J Pharmacol 1998 0.87
38 Participation of mitogen-activated protein kinase in thapsigargin- and TPA-induced histamine production in murine macrophage RAW 264.7 cells. Br J Pharmacol 2000 0.87
39 A detoxication route for acetaldehyde: metabolism of diacetyl, acetoin, and 2,3-butanediol in liver homogenate and perfused liver of rats. J Biochem 1996 0.86
40 Dexamethasone inhibits generation in inflammatory sites of the chemotactic activity attributable to leukotriene B4. Biochem Biophys Res Commun 1984 0.86
41 Stimulation by carcinogens and promoters of prostaglandin production by dog kidney (MDCK) cells in culture. Cancer Res 1978 0.86
42 Inhibition by troglitazone of the antigen-induced production of leukotrienes in immunoglobulin E-sensitized RBL-2H3 cells. Br J Pharmacol 2000 0.85
43 Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats. Naunyn Schmiedebergs Arch Pharmacol 2000 0.84
44 Synergistic stimulation of histamine release from rat peritoneal mast cells by 12-O-tetradecanoylphorbol 13-acetate (TPA)-type and non-TPA-type tumor promoters. Biochim Biophys Acta 1986 0.84
45 Degradation and turnover of collagen in the mouse skin and the effect of whole body x-irradiation. Biochim Biophys Acta 1970 0.84
46 Involvement of p38 MAPK and ERK/MAPK pathways in staurosporine-induced production of macrophage inflammatory protein-2 in rat peritoneal neutrophils. Biochim Biophys Acta 1999 0.83
47 Expression and purification of recombinant rat eosinophil-associated ribonucleases, homologues of human eosinophil cationic protein and eosinophil-derived neurotoxin, and their characterization. Int Arch Allergy Immunol 2001 0.83
48 alpha-Tocopherol inhibits 12-O-tetradecanoyl-phorbol-13-acetate-stimulated deacylation of cellular lipids, prostaglandin production, and changes in cell morphology of Madin-Darby canine kidney cells. Biochim Biophys Acta 1980 0.83
49 Inhibition by AA861 of prostaglandin E2 production by activated peritoneal macrophages of rat. Prostaglandins Leukot Med 1983 0.83
50 Mechanism of the inhibitory action of cyclooxygenase inhibitors on leukocyte infiltration: involvement of endogenous histamine. Eur J Pharmacol 1987 0.83
51 Induction of a delayed type hypersensitivity to carrageenin in mice. J Pharmacobiodyn 1982 0.82
52 Analysis of tumor-promoter-induced inflammation in rats: participation of histamine and prostaglandin E2. Biochim Biophys Acta 1987 0.82
53 Signal transduction cascade in staurosporine-induced prostaglandin E(2) production by rat peritoneal macrophages. J Pharmacol Exp Ther 2000 0.82
54 Gastric mucus secretion in portal hypertension. J Gastroenterol Hepatol 1989 0.82
55 Cystic adventitial disease of the popliteal artery--a case of young boy. Tohoku J Exp Med 1995 0.81
56 Involvement of a phosphatidylinositol 3-kinase-p38 mitogen activated protein kinase pathway in antigen-induced IL-4 production in mast cells. Biochim Biophys Acta 2000 0.81
57 Possible role for platelet-activating factor in neutrophil infiltration in allergic inflammation in rats. Int Arch Allergy Appl Immunol 1990 0.81
58 Preparation of recombinant rat interleukin-5 by baculovirus expression system and analysis of its biological activities. Biochim Biophys Acta 1999 0.81
59 Pharmacological analysis of the inflammatory exudate-induced histamine production in bone marrow cells. Immunopharmacology 1997 0.81
60 Correlation of leukocyte accumulation with chemotactic activity in the exudate of an allergic air-pouch inflammation. Int Arch Allergy Appl Immunol 1983 0.81
61 Prostaglandin E2 production dependent upon cyclooxygenase-1 and cyclooxygenase-2 and its contradictory modulation by auranofin in rat peritoneal macrophages. J Pharmacol Exp Ther 1997 0.81
62 Occurrence of histamine-production-increasing factor in the postanaphylactic phase of allergic inflammation. Int Arch Allergy Appl Immunol 1989 0.80
63 Possible participation of macrophage inflammatory protein 2 in neutrophil infiltration in allergic inflammation in rats. Biochim Biophys Acta 1997 0.80
64 Amino acid sequence of a C-type lectin CEL-IV from the marine invertebrate Cucumaria echinata. Biosci Biotechnol Biochem 1995 0.80
65 The effects of prostaglandin F2alpha on vascular permeability and collagen and non-collagen protein synthesis of preformed chronic carrageenin granuloma in rats. Biochem Pharmacol 1977 0.79
66 Slow reacting substance in the exudate of allergic air pouch inflammation in rats. Prostaglandins Leukot Med 1983 0.79
67 Change of prostaglandin E level in joint fluids after treatment with flurbiprofen in patients with rheumatoid arthritis and osteoarthritis. Ann Rheum Dis 1981 0.79
68 Leukocyte-derived neutrophil chemotactic factor-2 produced by infiltrated leukocytes in allergic inflammation model in rats is macrophage inflammatory protein-2. Immunol Invest 1995 0.79
69 Isolation and partial characterization of eosinophil granule proteins in rats--eosinophil cationic protein and major basic protein. Int Arch Allergy Immunol 1995 0.79
70 Possible participation of cyclooxygenase-2 in the recurrence of allergic inflammation in rats. Eur J Pharmacol 1997 0.78
71 Possible participation of a JAK2 signaling pathway in recombinant rat interleukin-5-induced prolongation of rat eosinophil survival. Biochim Biophys Acta 2001 0.78
72 Identification of histamine-production-increasing factor produced by stimulated RBL-2H3 rat basophilic leukemia cells as granulocyte-macrophage colony-stimulating factor. Biochim Biophys Acta 1998 0.78
73 Platelet-activating factor in the inflammatory exudate in the anaphylactic phase of allergic inflammation in rats. Int Arch Allergy Appl Immunol 1987 0.78
74 Mechanism of antianaphylactic action of beta-agonists in allergic inflammation of air pouch type in rats. Int Arch Allergy Appl Immunol 1987 0.78
75 Inhibition of tumor necrosis factor-alpha production by SK&F 98625, a CoA-independent transacylase inhibitor, in cultured rat peritoneal macrophages. Life Sci 1998 0.78
76 Pharmacological analysis of protein kinases responsible for chemotaxis of rat peritoneal neutrophils. Eur J Pharmacol 1998 0.78
77 Pharmacological influence of saikosaponins on prostaglandin E2 production by peritoneal macrophages. Planta Med 1985 0.78
78 Pharmacological analysis of neutrophil chemotactic factor production by leucocytes and roles of PAF in allergic inflammation in rats. Br J Pharmacol 1994 0.78
79 Prostaglandins E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 levels in carrageenin-induced inflammatory exudates in the rat air-pouch granuloma. Prostaglandins Med 1979 0.78
80 Possible roles of protein kinases in neutrophil chemotactic factor production by leucocytes in allergic inflammation in rats. Br J Pharmacol 1994 0.78
81 Inhibition by retinoids of antigen-induced IL-4 production in rat mast cell line RBL-2H3. Life Sci 2001 0.78
82 Role of phosphatidylinositol 3-kinase in degranulation induced by IgE-dependent and -independent mechanisms in rat basophilic RBL-2H3 (ml) cells. Cell Signal 1997 0.78
83 Analysis of biological activities of recombinant rat interleukin-5. Int Arch Allergy Immunol 1999 0.77
84 Inhibition by dexamethasone of histamine production in allergic inflammation in rats. J Immunol 1990 0.77
85 Chemotactic activity for neutrophils in allergic inflammation in rats. J Clin Lab Immunol 1990 0.77
86 Prostaglandin production by minced carrageenin granuloma tissue of rats and its inhibition by dexamethasone and cycloheximide. Prostaglandins Med 1980 0.77
87 Participation of protein kinases in staurosporine-induced interleukin-6 production by rat peritoneal macrophages. Br J Pharmacol 1999 0.77
88 Identification of cDNA encoding rat eosinophil cationic protein/eosinophil-associated ribonuclease. Biochim Biophys Acta 1997 0.77
89 Platelet-activating factor production in stimulated macrophages is down-regulated by concurrently produced prostaglandin E2. J Pharmacol Exp Ther 1996 0.77
90 Dual effects of staurosporine on arachidonic acid metabolism in rat peritoneal macrophages. Biochim Biophys Acta 1990 0.77
91 Inhibition by tectorigenin and tectoridin of prostaglandin E2 production and cyclooxygenase-2 induction in rat peritoneal macrophages. Biochim Biophys Acta 1999 0.77
92 Inhibition by auranofin of the production of prostaglandin E2 and nitric oxide in rat peritoneal macrophages. Eur J Pharmacol 1999 0.77
93 Analysis of the leukotriene D4 receptor in the granulation tissue of allergic inflammation in rats. Int Arch Allergy Immunol 1992 0.77
94 Enhancement by cyclo-oxygenase inhibitors of platelet-activating factor production in thapsigargin-stimulated macrophages. Br J Pharmacol 1995 0.77
95 A role of peripheral leukocytes in vascular permeability and edema formation in air pouch type allergic inflammation in rats. J Pharmacobiodyn 1991 0.77
96 A model analysis of aftereffects of high-intensity DC stimulation on action potential of ventricular muscle. IEEE Trans Biomed Eng 1998 0.77
97 Characterization of leukocyte-derived neutrophil chemotactic factor-2 and its possible roles in neutrophil infiltration in allergic inflammation in rats. Int Arch Allergy Immunol 1995 0.77
98 Expression of adhesion molecules in cultured human nasal mucosal microvascular endothelial cells activated by interleukin-1 beta or tumor necrosis factor-alpha: effects of dexamethasone. Int Arch Allergy Immunol 1998 0.76
99 Induction of nitric oxide synthase by lipopolysaccharide and its inhibition by auranofin in RAW 264.7 cells. Eur J Pharmacol 1997 0.76
100 Inhibition of prostaglandin E2 production by the isoflavones tectorigenin and tectoridin isolated from the rhizomes of Belamcanda chinensis. Planta Med 1999 0.76
101 A difference in prostaglandin E2 synthesis between cancer cells metastasizing into liver and kidney. Prostaglandins Leukot Med 1985 0.76
102 Dual effects of auranofin on prostaglandin E2 production by rat peritoneal macrophages. Eur J Pharmacol 1997 0.76
103 X-irradiation and ageing as reflected in the accumulation and insolubilization of collagen. Exp Gerontol 1968 0.75
104 Lectins modulate prostaglandin E2 production by rat peritoneal macrophages. Agents Actions 1984 0.75
105 Suppression of interleukin-1 alpha production by protein kinase C activators in human vascular endothelial cells. J Pharmacol Exp Ther 1995 0.75
106 Analysis of the expression of intercellular adhesion molecule-1 in cells of the human bronchial epithelial cell line NCI-H292. Eur J Pharmacol 1998 0.75
107 Alpha 1-antitrypsin and hepatic fibrosis. Br J Exp Pathol 1989 0.75
108 A difference in prostaglandin-producing ability between cancer cells metastasized into liver and kidney. Tohoku J Exp Med 1991 0.75
109 Negative regulation of MAP kinase by diacylglycerol-dependent mechanisms via G protein-coupled receptors in rat basophilic RBL-2H3 (ml) cells. Cell Signal 1997 0.75
110 Platelet-activating factor production in the stimulated macrophages is enhanced by the cyclooxygenase inhibitors. Adv Exp Med Biol 1996 0.75
111 [Regional adoptive immunotherapy using activated lymphocytes]. Gan To Kagaku Ryoho 1996 0.75
112 The effect of diphenylamine derivatives on arachidonic acid metabolism in rat peritoneal macrophages. Prostaglandins Leukot Med 1987 0.75
113 Adriamycin stimulates canine kidney (MDCK) cells to deacylate cellular lipids and to produce prostaglandins. Prostaglandins Med 1978 0.75
114 Some features of prostaglandin synthesis of the cancer cells metastasized into liver from gastric cancer lesions. Tohoku J Exp Med 1993 0.75
115 Identification of cDNA for rat homologues of human major basic protein and eosinophil cationic protein. Int Arch Allergy Immunol 1998 0.75
116 The distribution of alpha 1-antichymotrypsin and amyloid production in the brain in Alzheimer's disease. Virchows Arch B Cell Pathol Incl Mol Pathol 1992 0.75
117 [A case of hematological metastatic tumor of the liver from sigmoid colon cancer]. Nihon Shokakibyo Gakkai Zasshi 1993 0.75
118 Inhibition of prostalglandin E2 production by 2'-hydoxychalcone derivatives and the mechanism of action. J Pharm Pharmacol 2001 0.75
119 Morphological investigation of neurofibrillary tangles in Alzheimer's disease. Jpn J Psychiatry Neurol 1994 0.75
120 Characterization of methylated bovine serum albumin-induced allergic inflammation in rats. Int Arch Allergy Appl Immunol 1991 0.75
121 Expression of 74-kDa histidine decarboxylase protein in a macrophage-like cell line RAW 264.7 and inhibition by dexamethasone. Eur J Pharmacol 2001 0.75
122 [Analysis of chemical mediators in inflammatory reactions and the mechanism of anti-inflammatory drugs]. Yakugaku Zasshi 1988 0.75
123 Stimulation of prostaglandin E2 production and induction of specific protein synthesis in rat peritoneal macrophages by a tumor promoter staurosporine. J Cancer Res Clin Oncol 1993 0.75
124 The purification of arylsulfatases A and B. Biochem Med 1984 0.75
125 The mechanism of histamine production in allergic inflammation. Methods Find Exp Clin Pharmacol 1995 0.75
126 [Anti-inflammatory substances]. Tanpakushitsu Kakusan Koso 2000 0.75
127 [A case of malignant lymphoma (clear cell type) probably derived from immunoblastic lymphadenopathy]. Rinsho Ketsueki 1984 0.75
128 Three-dimensional reconstruction of semi-gross biostructures using 'macroserials'--1-mm-thick serial organ slices. J Microsc 1988 0.75
129 Increase in histamine production by inflammatory exudate in the chronic phase of allergic inflammation in rats. Inflammation 1998 0.75
130 Antiinflammatory actions of ephedrines in acute inflammations. Planta Med 1985 0.75
131 Stimulation of arachidonic acid metabolism by a streptococcal preparation (OK-432) in rat peritoneal macrophages. Biochim Biophys Acta 1992 0.75
132 Dexamethasone inhibits the production of macrophage inflammatory protein 2 in the leukocytes in rat allergic inflammation. Eur J Pharmacol 1995 0.75
133 Role of arachidonate metabolites in allergic inflammation in rats. Adv Prostaglandin Thromboxane Leukot Res 1985 0.75
134 [Regulation of histamine production in macrophages]. Nihon Yakurigaku Zasshi 2001 0.75
135 Desensitization to locally injected PGF2 alpha as reflected in the vascular permeability and collagen and noncollagenous protein synthesis of carrageenin-induced granulation tissue in rats. Biochem Pharmacol 1980 0.75
136 Mercury dynamics in hair of rats exposed to methylmercury by synchrotron radiation X-ray fluorescence imaging. Life Sci 1997 0.75
137 Inhibition of 15-hydroxyprostaglandin dehydrogenase by 9,11-deoxyprostaglandins in vitro and in vivo. Mol Pharmacol 1981 0.75
138 Mechanism of inhibitory action of mesaconitine in acute inflammations. Eur J Pharmacol 1982 0.75
139 Design and evaluation of a single-pivot supported centrifugal blood pump. Artif Organs 2001 0.75
140 Inhibition of histamine release from RBL-2H3 cells by protein synthesis inhibitors. Int Arch Allergy Immunol 1994 0.75
141 Some features of the metastatic cancer cells in prostaglandin production. Tohoku J Exp Med 1989 0.75
142 Estimation of left ventricular recovery level based on the motor current waveform analysis on circulatory support with centrifugal blood pump. Artif Organs 2001 0.75
143 Effects of JTE-522, a specific inhibitor of cyclooxygenase-2, on the recurrence of allergic inflammation in rats. Eur J Pharmacol 1998 0.75
144 [Equipment and instruments for use in radiological protection. VIII. Characteristics and use of radiation protection apparatus (2)]. Radioisotopes 1988 0.75
145 Radiation fibrosis of guinea pig skin after beta irradiation and an attempt at its suppression with proline analogs. Radiat Res 1979 0.75
146 Suppression by dexamethasone of vascular permeability responses induced with leukotrienes C and D in the rat skin. Prostaglandins 1981 0.75
147 Phospholipase A2 activity in carrageenin-induced inflammatory tissue of rats. Biochem Pharmacol 1982 0.75
148 Cloning of cDNA for rat eosinophil major basic protein. Biochim Biophys Acta 1995 0.75
149 Recurrence of an allergic inflammation of air-pouch type in rats and possible participation of prostaglandin E2. Int Arch Allergy Appl Immunol 1987 0.75
150 Corrigendum to "Cloning of cDNA for rat eosinophil major basic protein" [Biochim. Biophys. Acta 1264 (1995) 261-264]. Biochim Biophys Acta 1996 0.75
151 Increase of eosinophilic cell population in bone marrow of rats by immunization with Ascaris suum antigen. Immunol Invest 1997 0.75
152 Analysis of the prolongation of rat eosinophil survival induced by recombinant rat interleukin-5. Int Arch Allergy Immunol 2000 0.75
153 Some features in prostaglandin synthesis of the cancer cells which metastasized into liver from intestinal cancer lesions. Tohoku J Exp Med 1993 0.75