Published in Br J Pharmacol on July 01, 1999
In vivo evidence for a role of protein kinase C in peripheral nociceptive processing. Br J Pharmacol (2002) 0.96
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
Studies and perspectives of protein kinase C. Science (1986) 14.73
Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry (1984) 10.83
Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase. Biochem Biophys Res Commun (1986) 7.96
Protein kinase C: structure, function, and regulation. J Biol Chem (1995) 5.55
A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages. J Cell Biol (1996) 5.52
PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase. Curr Biol (1995) 4.52
Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem Biophys Res Commun (1989) 4.24
K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem Biophys Res Commun (1987) 3.46
Phorbol esters stimulate macropinocytosis and solute flow through macrophages. J Cell Sci (1989) 3.09
Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3. J Biol Chem (1994) 3.08
Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase. J Biol Chem (1994) 1.94
Synthesis of interleukin 6 (interferon-beta 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP. J Biol Chem (1988) 1.94
Activation of human neutrophil phospholipase D by three separable mechanisms. FASEB J (1990) 1.50
Receptor specificity of growth factor-stimulated synthesis of 3-phosphorylated inositol lipids in Swiss 3T3 cells. J Biol Chem (1992) 1.40
Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events. J Exp Med (1995) 1.36
Sequential cytokine dynamics in chronic rejection of rat renal allografts: roles for cytokines RANTES and MCP-1. Proc Natl Acad Sci U S A (1995) 1.34
Analysis of the stimulative effect of thapsigargin, a non-TPA-type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages. Br J Pharmacol (1988) 1.28
Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-zeta in bacterial lipopolysaccharide-treated human monocytes. J Biol Chem (1997) 1.26
Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents. Biochem Pharmacol (1997) 1.09
Thapsigargin and cyclopiazonic acid initiate rapid and dramatic increases of IL-6 mRNA expression and IL-6 secretion in murine peritoneal macrophages. J Immunol (1995) 1.04
A novel conformationally restricted protein kinase C inhibitor, Ro 31-8425, inhibits human neutrophil superoxide generation by soluble, particulate and post-receptor stimuli. FEBS Lett (1991) 0.97
Novel functions of phosphatidylinositol 3-kinase in terminally differentiated cells. Cell Signal (1995) 0.96
Stimulation of prostaglandin E2 production by 12-O-tetradecanoylphorbol 13-acetate (TPA)-type and non-TPA-type tumor promoters in macrophages and its inhibition by cycloheximide. Biochim Biophys Acta (1985) 0.95
Legionella pneumophila heat-shock protein-induced increase of interleukin-1 beta mRNA involves protein kinase C signalling in macrophages. Immunology (1996) 0.94
Induction of neutrophil chemotactic factor production by staurosporine in rat peritoneal neutrophils. Br J Pharmacol (1997) 0.92
The phosphatidylinositol 3-kinase inhibitor wortmannin blocks mast cell exocytosis but not IL-6 production. J Immunol (1996) 0.91
Induction by staurosporine of nitric oxide synthase expression in vascular smooth muscle cells: role of NF-kappa B, CREB and C/EBP beta. Br J Pharmacol (1997) 0.90
Regulation of interleukin-6 (IL-6) expression: evidence for a tissue-specific role of protein kinase C. J Clin Immunol (1993) 0.84
Interleukin-1 beta uses common and distinct signaling pathways for induction of the interleukin-6 and tumor necrosis factor alpha genes in the human astrocytoma cell line U373. J Neurochem (1996) 0.84
Staurosporine-induced neurite outgrowth in PC12h cells. Exp Cell Res (1989) 0.83
Transcriptional regulation of neuromodulin (GAP-43) in mouse neuroblastoma clone N1E-115 as evaluated by the RT/PCR method. Brain Res Mol Brain Res (1992) 0.83
Induction of PC12 cell death, apoptosis, by a sialoglycopeptide from bovine brain. Biochem Biophys Res Commun (1994) 0.81
Differential effects of protein kinase C inhibitors on chemokine production in human synovial fibroblasts. Br J Pharmacol (1996) 0.81
Staurosporine induces tyrosine phosphorylation of a 145 kDa protein but does not activate gp140trk in PC12 cells. Eur J Pharmacol (1994) 0.80
Inhibition of tumor necrosis factor-alpha production by SK&F 98625, a CoA-independent transacylase inhibitor, in cultured rat peritoneal macrophages. Life Sci (1998) 0.78
Tyrosine kinase activity is essential for interleukin-1 beta--stimulated production of interleukin-6 in U373 human astrocytoma cells. J Neurochem (1995) 0.78
Signal transduction pathways involved in tumour necrosis factor secretion by Plasmodium falciparum-stimulated human monocytes. Immunology (1994) 0.78
Staurosporine stimulates phospholipase D activation in human polymorphonuclear leukocytes. FEBS Lett (1993) 0.78
Alpha1-adrenoceptor subtype activation increases proto-oncogene mRNA levels. Role of protein kinase C. Eur J Pharmacol (1998) 0.78
Dual effects of staurosporine on arachidonic acid metabolism in rat peritoneal macrophages. Biochim Biophys Acta (1990) 0.77
Mice lacking histidine decarboxylase exhibit abnormal mast cells. FEBS Lett (2001) 2.15
Intraepithelial CD8+ T-cell-count becomes a prognostic factor after a longer follow-up period in human colorectal carcinoma: possible association with suppression of micrometastasis. Br J Cancer (2004) 1.80
Determination of cyclooxygenase products and prostaglandin metabolites using high-pressure liquid chromatography and radioimmunoassay. Anal Biochem (1979) 1.72
Glycyrrhizin inhibits prostaglandin E2 production by activated peritoneal macrophages from rats. Prostaglandins Med (1981) 1.21
The content of prostaglandin E and prostaglandin F2alpha in the exudate of carrageenin granuloma of rats. Biochim Biophys Acta (1976) 1.14
Induction of an allergic air-pouch inflammation in rats. Int Arch Allergy Appl Immunol (1982) 1.13
Retinoids as well as tumour promoters enhance deacylation of cellular lipids and prostaglandin production in MDCK cells. Nature (1978) 1.11
Cyclooxygenase-2-mediated angiogenesis in carrageenin-induced granulation tissue in rats. J Pharmacol Exp Ther (2000) 1.10
Novel roles of CpG oligodeoxynucleotides as a leader for the sampling and presentation of CpG-tagged antigen by dendritic cells. J Immunol (2001) 1.09
Antiinflammatory actions of ephedrines in acute inflammations1. Planta Med (1985) 1.04
Mechanisms underlying the attenuation of endothelium-dependent vasodilatation in the mesenteric arterial bed of the streptozotocin-induced diabetic rat. Br J Pharmacol (2000) 1.03
Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors. Br J Pharmacol (2001) 1.03
Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum. Planta Med (2001) 1.00
A possible role of arachidonate metabolism in allergic air pouch inflammation in rats. Anti-inflammatory effect of indomethacin and dexamethasone and the level of prostaglandin E2 in the exudate. Int Arch Allergy Appl Immunol (1982) 0.99
Tumor promoting phorbol diesters stimulate release of radioactivity from [3H]-arachidonic acid labeled- but not [14C]linoleic acid labeled-cells. Indomethacin inhibits the stimulated release from [3H] arachidonate labeled cells. Prostaglandins Med (1978) 0.99
Role of endogenous histamine in postanaphylactic phase of allergic inflammation in rats. J Pharmacol Exp Ther (1987) 0.99
Stimulation of arachidonic acid metabolism in rat peritoneal macrophages by thapsigargin, a non-(12-O-tetradecanoylphorbol-13-acetate) (TPA)-type tumor promoter. J Cancer Res Clin Oncol (1987) 0.97
Stimulation of prostaglandin E2 production by 12-O-tetradecanoylphorbol 13-acetate (TPA)-type and non-TPA-type tumor promoters in macrophages and its inhibition by cycloheximide. Biochim Biophys Acta (1985) 0.95
Stimulation of neutrophil adherence to vascular endothelial cells by histamine and thrombin and its inhibition by PAF antagonists and dexamethasone. Br J Pharmacol (1991) 0.95
Comparative study between steroidal and nonsteroidal anti-inflammatory drugs on the mode of their actions on vascular permeability in rat carrageenin-air-pouch inflammation. J Pharmacobiodyn (1980) 0.94
Analysis of histamine-producing cells at the late phase of allergic inflammation in rats. Immunology (2000) 0.93
Induction of neutrophil chemotactic factor production by staurosporine in rat peritoneal neutrophils. Br J Pharmacol (1997) 0.92
Pharmacological analysis of the vascular permeability response in the anaphylactic phase of allergic inflammation in rats. Eur J Pharmacol (1985) 0.92
Reduction by dexamethasone of chemotactic activity in inflammatory exudates. Eur J Pharmacol (1984) 0.92
Induction of neutrophil infiltration by rat chemotactic cytokine (CINC) and its inhibition by dexamethasone in rats. Inflammation (1992) 0.92
Protocollagen proline hydroxylase in isolated rat liver cells. Biochim Biophys Acta (1972) 0.92
Morphological study of amyloid fibrils and preamyloid deposits in the brain with Alzheimer's disease. Acta Neuropathol (1992) 0.92
Arachidonate metabolites in acute and chronic allergic air pouch inflammation in rats and the anti-inflammatory effects of indomethacin and dexamethasone. Int Arch Allergy Appl Immunol (1984) 0.91
Downward regulation of neutrophil infiltration by endogenous histamine without affecting vascular permeability responses in air-pouch-type carrageenin inflammation in rats. Inflammation (1991) 0.90
Delayed-type hypersensitivity as revealed on the footpads of mice to azobenzenearsonate-acetyl bovine serum albumin. Int Arch Allergy Appl Immunol (1981) 0.90
Vascular permeability responses and the role of prostaglandin E2 in an experimental allergic inflammation of air pouch type in rats. Br J Pharmacol (1986) 0.89
Possible participation of intracellular platelet-activating factor in tumor necrosis factor-alpha production by rat peritoneal macrophages. Eur J Pharmacol (1999) 0.89
Inhibition by dexamethasone of antigen-induced c-Jun N-terminal kinase activation in rat basophilic leukemia cells. J Immunol (1998) 0.89
Generation of rat eosinophils by recombinant rat interleukin-5 in vitro and in vivo. Biochim Biophys Acta (2000) 0.88
Orosomucoid as the accelerator of hepatic fibrosis. Br J Exp Pathol (1986) 0.88
Effects of glucocorticoids on apoptosis of infiltrated eosinophils and neutrophils in rats. Eur J Pharmacol (1998) 0.87
Participation of mitogen-activated protein kinase in thapsigargin- and TPA-induced histamine production in murine macrophage RAW 264.7 cells. Br J Pharmacol (2000) 0.87
Dexamethasone inhibits generation in inflammatory sites of the chemotactic activity attributable to leukotriene B4. Biochem Biophys Res Commun (1984) 0.86
Stimulation by carcinogens and promoters of prostaglandin production by dog kidney (MDCK) cells in culture. Cancer Res (1978) 0.86
A detoxication route for acetaldehyde: metabolism of diacetyl, acetoin, and 2,3-butanediol in liver homogenate and perfused liver of rats. J Biochem (1996) 0.86
Inhibition by troglitazone of the antigen-induced production of leukotrienes in immunoglobulin E-sensitized RBL-2H3 cells. Br J Pharmacol (2000) 0.85
Synergistic stimulation of histamine release from rat peritoneal mast cells by 12-O-tetradecanoylphorbol 13-acetate (TPA)-type and non-TPA-type tumor promoters. Biochim Biophys Acta (1986) 0.84
Degradation and turnover of collagen in the mouse skin and the effect of whole body x-irradiation. Biochim Biophys Acta (1970) 0.84
Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats. Naunyn Schmiedebergs Arch Pharmacol (2000) 0.84
Involvement of p38 MAPK and ERK/MAPK pathways in staurosporine-induced production of macrophage inflammatory protein-2 in rat peritoneal neutrophils. Biochim Biophys Acta (1999) 0.83
alpha-Tocopherol inhibits 12-O-tetradecanoyl-phorbol-13-acetate-stimulated deacylation of cellular lipids, prostaglandin production, and changes in cell morphology of Madin-Darby canine kidney cells. Biochim Biophys Acta (1980) 0.83
Expression and purification of recombinant rat eosinophil-associated ribonucleases, homologues of human eosinophil cationic protein and eosinophil-derived neurotoxin, and their characterization. Int Arch Allergy Immunol (2001) 0.83
Inhibition by AA861 of prostaglandin E2 production by activated peritoneal macrophages of rat. Prostaglandins Leukot Med (1983) 0.83
Mechanism of the inhibitory action of cyclooxygenase inhibitors on leukocyte infiltration: involvement of endogenous histamine. Eur J Pharmacol (1987) 0.83
Induction of a delayed type hypersensitivity to carrageenin in mice. J Pharmacobiodyn (1982) 0.82
Signal transduction cascade in staurosporine-induced prostaglandin E(2) production by rat peritoneal macrophages. J Pharmacol Exp Ther (2000) 0.82
Analysis of tumor-promoter-induced inflammation in rats: participation of histamine and prostaglandin E2. Biochim Biophys Acta (1987) 0.82
Gastric mucus secretion in portal hypertension. J Gastroenterol Hepatol (1989) 0.82
Involvement of a phosphatidylinositol 3-kinase-p38 mitogen activated protein kinase pathway in antigen-induced IL-4 production in mast cells. Biochim Biophys Acta (2000) 0.81
Pharmacological analysis of the inflammatory exudate-induced histamine production in bone marrow cells. Immunopharmacology (1997) 0.81
Correlation of leukocyte accumulation with chemotactic activity in the exudate of an allergic air-pouch inflammation. Int Arch Allergy Appl Immunol (1983) 0.81
Preparation of recombinant rat interleukin-5 by baculovirus expression system and analysis of its biological activities. Biochim Biophys Acta (1999) 0.81
Possible role for platelet-activating factor in neutrophil infiltration in allergic inflammation in rats. Int Arch Allergy Appl Immunol (1990) 0.81
Prostaglandin E2 production dependent upon cyclooxygenase-1 and cyclooxygenase-2 and its contradictory modulation by auranofin in rat peritoneal macrophages. J Pharmacol Exp Ther (1997) 0.81
Cystic adventitial disease of the popliteal artery--a case of young boy. Tohoku J Exp Med (1995) 0.81
Possible participation of macrophage inflammatory protein 2 in neutrophil infiltration in allergic inflammation in rats. Biochim Biophys Acta (1997) 0.80
Amino acid sequence of a C-type lectin CEL-IV from the marine invertebrate Cucumaria echinata. Biosci Biotechnol Biochem (1995) 0.80
Occurrence of histamine-production-increasing factor in the postanaphylactic phase of allergic inflammation. Int Arch Allergy Appl Immunol (1989) 0.80
Slow reacting substance in the exudate of allergic air pouch inflammation in rats. Prostaglandins Leukot Med (1983) 0.79
Leukocyte-derived neutrophil chemotactic factor-2 produced by infiltrated leukocytes in allergic inflammation model in rats is macrophage inflammatory protein-2. Immunol Invest (1995) 0.79
Change of prostaglandin E level in joint fluids after treatment with flurbiprofen in patients with rheumatoid arthritis and osteoarthritis. Ann Rheum Dis (1981) 0.79
The effects of prostaglandin F2alpha on vascular permeability and collagen and non-collagen protein synthesis of preformed chronic carrageenin granuloma in rats. Biochem Pharmacol (1977) 0.79
Isolation and partial characterization of eosinophil granule proteins in rats--eosinophil cationic protein and major basic protein. Int Arch Allergy Immunol (1995) 0.79
Pharmacological influence of saikosaponins on prostaglandin E2 production by peritoneal macrophages. Planta Med (1985) 0.78
Pharmacological analysis of neutrophil chemotactic factor production by leucocytes and roles of PAF in allergic inflammation in rats. Br J Pharmacol (1994) 0.78
Identification of histamine-production-increasing factor produced by stimulated RBL-2H3 rat basophilic leukemia cells as granulocyte-macrophage colony-stimulating factor. Biochim Biophys Acta (1998) 0.78
Mechanism of antianaphylactic action of beta-agonists in allergic inflammation of air pouch type in rats. Int Arch Allergy Appl Immunol (1987) 0.78
Possible roles of protein kinases in neutrophil chemotactic factor production by leucocytes in allergic inflammation in rats. Br J Pharmacol (1994) 0.78
Inhibition of tumor necrosis factor-alpha production by SK&F 98625, a CoA-independent transacylase inhibitor, in cultured rat peritoneal macrophages. Life Sci (1998) 0.78
Possible participation of cyclooxygenase-2 in the recurrence of allergic inflammation in rats. Eur J Pharmacol (1997) 0.78
Possible participation of a JAK2 signaling pathway in recombinant rat interleukin-5-induced prolongation of rat eosinophil survival. Biochim Biophys Acta (2001) 0.78
Role of phosphatidylinositol 3-kinase in degranulation induced by IgE-dependent and -independent mechanisms in rat basophilic RBL-2H3 (ml) cells. Cell Signal (1997) 0.78
Inhibition by retinoids of antigen-induced IL-4 production in rat mast cell line RBL-2H3. Life Sci (2001) 0.78
Pharmacological analysis of protein kinases responsible for chemotaxis of rat peritoneal neutrophils. Eur J Pharmacol (1998) 0.78
Prostaglandins E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 levels in carrageenin-induced inflammatory exudates in the rat air-pouch granuloma. Prostaglandins Med (1979) 0.78
Platelet-activating factor in the inflammatory exudate in the anaphylactic phase of allergic inflammation in rats. Int Arch Allergy Appl Immunol (1987) 0.78
Analysis of biological activities of recombinant rat interleukin-5. Int Arch Allergy Immunol (1999) 0.77
Inhibition by dexamethasone of histamine production in allergic inflammation in rats. J Immunol (1990) 0.77
Platelet-activating factor production in stimulated macrophages is down-regulated by concurrently produced prostaglandin E2. J Pharmacol Exp Ther (1996) 0.77
Characterization of leukocyte-derived neutrophil chemotactic factor-2 and its possible roles in neutrophil infiltration in allergic inflammation in rats. Int Arch Allergy Immunol (1995) 0.77
A model analysis of aftereffects of high-intensity DC stimulation on action potential of ventricular muscle. IEEE Trans Biomed Eng (1998) 0.77
Dual effects of staurosporine on arachidonic acid metabolism in rat peritoneal macrophages. Biochim Biophys Acta (1990) 0.77
Enhancement by cyclo-oxygenase inhibitors of platelet-activating factor production in thapsigargin-stimulated macrophages. Br J Pharmacol (1995) 0.77
Inhibition by tectorigenin and tectoridin of prostaglandin E2 production and cyclooxygenase-2 induction in rat peritoneal macrophages. Biochim Biophys Acta (1999) 0.77
Inhibition by auranofin of the production of prostaglandin E2 and nitric oxide in rat peritoneal macrophages. Eur J Pharmacol (1999) 0.77
A role of peripheral leukocytes in vascular permeability and edema formation in air pouch type allergic inflammation in rats. J Pharmacobiodyn (1991) 0.77
Analysis of the leukotriene D4 receptor in the granulation tissue of allergic inflammation in rats. Int Arch Allergy Immunol (1992) 0.77
Chemotactic activity for neutrophils in allergic inflammation in rats. J Clin Lab Immunol (1990) 0.77
Prostaglandin production by minced carrageenin granuloma tissue of rats and its inhibition by dexamethasone and cycloheximide. Prostaglandins Med (1980) 0.77
Identification of cDNA encoding rat eosinophil cationic protein/eosinophil-associated ribonuclease. Biochim Biophys Acta (1997) 0.77
Expression of adhesion molecules in cultured human nasal mucosal microvascular endothelial cells activated by interleukin-1 beta or tumor necrosis factor-alpha: effects of dexamethasone. Int Arch Allergy Immunol (1998) 0.76
Dual effects of auranofin on prostaglandin E2 production by rat peritoneal macrophages. Eur J Pharmacol (1997) 0.76
Induction of nitric oxide synthase by lipopolysaccharide and its inhibition by auranofin in RAW 264.7 cells. Eur J Pharmacol (1997) 0.76
A difference in prostaglandin E2 synthesis between cancer cells metastasizing into liver and kidney. Prostaglandins Leukot Med (1985) 0.76