Published in Immunol Cell Biol on August 01, 1999
The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse. Immunity (2009) 2.16
The half-life of the T-cell receptor/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge. Immunology (2007) 0.98
Phenotypic models of T cell activation. Nat Rev Immunol (2014) 0.94
T-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APC. Proc Natl Acad Sci U S A (2009) 0.85
Contribution of TCR signaling strength to CD8+ T cell peripheral tolerance mechanisms. J Immunol (2014) 0.80
Gads regulates the expansion phase of CD8+ T cell-mediated immunity. J Immunol (2011) 0.78
Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets. J Immunol (2016) 0.75
Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment. Nat Commun (2017) 0.75
T cell receptor antagonist peptides induce positive selection. Cell (1994) 18.66
Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature (1998) 11.08
Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol Cell Biol (1998) 11.07
Introduction of soluble protein into the class I pathway of antigen processing and presentation. Cell (1988) 8.01
Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells. J Exp Med (1997) 5.72
Constitutive class I-restricted exogenous presentation of self antigens in vivo. J Exp Med (1996) 5.21
Cross-presentation, dendritic cells, tolerance and immunity. Annu Rev Immunol (2001) 5.15
Induction of a CD8+ cytotoxic T lymphocyte response by cross-priming requires cognate CD4+ T cell help. J Exp Med (1997) 4.01
Secretion of a malarial histidine-rich protein (Pf HRP II) from Plasmodium falciparum-infected erythrocytes. J Cell Biol (1986) 3.51
CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes. Nature (1996) 3.08
Cutting edge: intravenous soluble antigen is presented to CD4 T cells by CD8- dendritic cells, but cross-presented to CD8 T cells by CD8+ dendritic cells. J Immunol (2001) 3.05
The need for IgG2c specific antiserum when isotyping antibodies from C57BL/6 and NOD mice. J Immunol Methods (1998) 2.78
The development, maturation, and turnover rate of mouse spleen dendritic cell populations. J Immunol (2000) 2.76
Cross-presentation in viral immunity and self-tolerance. Nat Rev Immunol (2001) 2.76
Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells. J Exp Med (1993) 2.57
CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity. J Exp Med (1997) 2.49
Cell-associated ovalbumin is cross-presented much more efficiently than soluble ovalbumin in vivo. J Immunol (2001) 2.41
Characterization of T cell receptor gamma chain expression in a subset of murine thymocytes. Science (1986) 2.40
Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destruction. J Exp Med (1998) 2.24
Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice. Diabetes (1997) 2.19
Characterization of the ovalbumin-specific TCR transgenic line OT-I: MHC elements for positive and negative selection. Immunol Cell Biol (2000) 1.98
The cytotoxic T-cell response to herpes simplex virus type 1 infection of C57BL/6 mice is almost entirely directed against a single immunodominant determinant. J Virol (1999) 1.97
An inexpensive alternative to glassmilk for DNA purification. Trends Genet (1995) 1.91
The importance of antibody affinity in the performance of immunoassays for antibody. J Immunol Methods (1985) 1.89
Cross-tolerance: a pathway for inducing tolerance to peripheral tissue antigens. J Exp Med (1998) 1.83
Cross-presentation: a general mechanism for CTL immunity and tolerance. Immunol Today (1998) 1.82
Evidence for the role of a human intestinal adenovirus in the pathogenesis of coeliac disease. Gut (1987) 1.79
Self-ignorance in the peripheral T-cell pool. Immunol Rev (1993) 1.73
Induction of autoimmune diabetes by oral administration of autoantigen. Science (1996) 1.69
Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules. J Exp Med (1996) 1.66
Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor. Mol Cell Endocrinol (1997) 1.62
Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes. J Exp Med (1995) 1.57
Activation and migration of CD8 T cells in the intestinal mucosa. J Immunol (1997) 1.56
CD8 T cell ignorance or tolerance to islet antigens depends on antigen dose. Proc Natl Acad Sci U S A (1999) 1.55
Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes. Nature (1989) 1.52
Class I-restricted presentation occurs without internalization or processing of exogenous antigenic peptides. J Immunol (1989) 1.49
Thy-1+ dendritic epidermal cells express T3 antigen and the T-cell receptor gamma chain. Proc Natl Acad Sci U S A (1987) 1.48
The peripheral deletion of autoreactive CD8+ T cells induced by cross-presentation of self-antigens involves signaling through CD95 (Fas, Apo-1). J Exp Med (1998) 1.47
Ontogeny of T cell tolerance to peripherally expressed antigens. Proc Natl Acad Sci U S A (1999) 1.43
Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune induction. Nature (1998) 1.41
Peripheral deletion of autoreactive CD8+ T cells in transgenic mice expressing H-2Kb in the liver. Eur J Immunol (1995) 1.40
Secretion of a soluble class I molecule encoded by the Q10 gene of the C57BL/10 mouse. EMBO J (1985) 1.40
Characterization of diverse primary herpes simplex virus type 1 gB-specific cytotoxic T-cell response showing a preferential V beta bias. J Virol (1995) 1.40
FoLT PCR: a simple PCR protocol for amplifying DNA directly from whole blood. Biotechniques (1993) 1.38
Species-restricted interactions between CD8 and the alpha 3 domain of class I influence the magnitude of the xenogeneic response. J Exp Med (1989) 1.35
Influence of cellular location of expressed antigen on the efficacy of DNA vaccination: cytotoxic T lymphocyte and antibody responses are suboptimal when antigen is cytoplasmic after intramuscular DNA immunization. Int Immunol (1997) 1.33
Structure of the apical membrane antigen I (AMA-1) of Plasmodium chabaudi. Mol Biochem Parasitol (1989) 1.32
The effect of mutations in the MHC class I peptide binding groove on the cytotoxic T lymphocyte recognition of the Kb-restricted ovalbumin determinant. Eur J Immunol (1990) 1.30
Mouse loci for malaria-induced mortality and the control of parasitaemia. Nat Genet (1997) 1.29
Thymus-dependent and thymus-independent developmental pathways for peripheral T cell receptor-gamma delta-bearing lymphocytes. J Immunol (1988) 1.29
The measurement of antibody affinity: a comparison of five techniques utilizing a panel of monoclonal anti-DNP antibodies and the effect of high affinity antibody on the measurement of low affinity antibody. J Immunol Methods (1983) 1.28
Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes. Mol Med (1995) 1.28
DNA immunization: induction of higher avidity antibody and effect of route on T cell cytotoxicity. Proc Natl Acad Sci U S A (1997) 1.27
Expression of two T cell receptor alpha chains on the surface of normal murine T cells. Eur J Immunol (1995) 1.27
BAC-VAC, a novel generation of (DNA) vaccines: A bacterial artificial chromosome (BAC) containing a replication-competent, packaging-defective virus genome induces protective immunity against herpes simplex virus 1. Proc Natl Acad Sci U S A (1999) 1.26
Is IgG2a a good Th1 marker in mice? Immunol Today (1998) 1.26
The effect of epitope density and antibody affinity on the ELISA as analysed by monoclonal antibodies. J Immunol Methods (1984) 1.25
Predominant transgene expression in exocrine pancreas directed by the CMV promoter. DNA Cell Biol (2000) 1.25
Identification of conserved T cell receptor CDR3 residues contacting known exposed peptide side chains from a major histocompatibility complex class I-bound determinant. Eur J Immunol (1993) 1.24
Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells. Nature (1999) 1.23
Junctional biases in the naive TCR repertoire control the CTL response to an immunodominant determinant of HSV-1. Immunity (2000) 1.22
B cells directly tolerize CD8(+) T cells. J Exp Med (1998) 1.20
SOCS1: a potent and multifaceted regulator of cytokines and cell-mediated inflammation. Tissue Antigens (2006) 1.20
Five groups of antigenic determinants on DNA identified by monoclonal antibodies from (NZB X NZW)F1 and MRL/Mp-lpr/lpr mice. Immunology (1985) 1.20
MHC class II expression is regulated in dendritic cells independently of invariant chain degradation. Immunity (2001) 1.18
Antigen-specific CD8+ T cell subset distribution in lymph nodes draining the site of herpes simplex virus infection. Eur J Immunol (1997) 1.18
Antifolate drug selection results in duplication and rearrangement of chromosome 7 in Plasmodium chabaudi. Mol Cell Biol (1989) 1.16
T cell receptor (TCR) antagonism without a negative signal: evidence from T cell hybridomas expressing two independent TCRs. J Exp Med (1999) 1.15
Salmonella typhimurium delta aroA delta aroD mutants expressing a foreign recombinant protein induce specific major histocompatibility complex class I-restricted cytotoxic T lymphocytes in mice. Infect Immun (1993) 1.14
Processing of a minimal antigenic peptide alters its interaction with MHC molecules. Nature (1988) 1.12
Induction of peripheral CD8+ T-cell tolerance by cross-presentation of self antigens. Immunol Rev (1998) 1.10
Immunity or tolerance? That is the question for dendritic cells. Nat Immunol (2001) 1.09
Peptide antagonists that promote positive selection are inefficient at T cell activation and thymocyte deletion. Eur J Immunol (1994) 1.08
Cytotoxic T lymphocyte activation by cross-priming. Curr Opin Immunol (1999) 1.07
Herpes simplex virus type 1-specific cytotoxic T-lymphocyte arming occurs within lymph nodes draining the site of cutaneous infection. J Virol (2000) 1.07
Molecular cloning of a C-type lectin superfamily protein differentially expressed by CD8alpha(-) splenic dendritic cells. Mol Immunol (2001) 1.06
Both intrathymic and peripheral selection modulate the differential expression of V beta 5 among CD4+ and CD8+ T cells. J Exp Med (1992) 1.06
Class I genes and molecules: an update. Immunology (1986) 1.05
TCR alpha-chain usage can determine antigen-selected TCR beta-chain repertoire diversity. J Immunol (1996) 1.03