Published in J Biol Chem on September 03, 1999
Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development. Nat Med (2008) 3.33
Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects--a monozygotic twin study. PLoS One (2007) 2.38
Lysophosphatidic acid induces neointima formation through PPARgamma activation. J Exp Med (2004) 1.86
Platelet-activating factor, a molecular sensor for cellular damage, activates systemic immune suppression. J Exp Med (2002) 1.83
The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses. Biochimie (2010) 1.30
Aldose reductase-catalyzed reduction of aldehyde phospholipids. J Biol Chem (2004) 1.10
Fatty acid oxidation in the pathogenesis of Alzheimer's disease. Am J Pathol (2005) 1.04
Trypanosoma cruzi infection is enhanced by vector saliva through immunosuppressant mechanisms mediated by lysophosphatidylcholine. Infect Immun (2008) 1.00
Noninvasive molecular imaging reveals role of PAF in leukocyte-endothelial interaction in LPS-induced ocular vascular injury. FASEB J (2011) 0.93
The acyl-acyl carrier protein synthetase from Synechocystis sp. PCC 6803 mediates fatty acid import. Plant Physiol (2012) 0.89
PAF-acetylhydrolase expressed during megakaryocyte differentiation inactivates PAF-like lipids. Blood (2009) 0.85
Two of the usual suspects, platelet-activating factor and its receptor, implicated in acute lung injury. J Clin Invest (1999) 0.85
Critical insights into cardiovascular disease from basic research on the oxidation of phospholipids: the γ-hydroxyalkenal phospholipid hypothesis. Chem Res Toxicol (2011) 0.85
Nature of interactions between PEO-PPO-PEO triblock copolymers and lipid membranes: (I) effect of polymer hydrophobicity on its ability to protect liposomes from peroxidation. Biomacromolecules (2012) 0.82
Mechanisms underlying lysophosphatidylcholine-induced potentiation of vascular contractions in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat aorta. Br J Pharmacol (2006) 0.81
Phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to intracellular adhesion molecule-1. J Lipid Res (2008) 0.81
Design and synthesis of a stable oxidized phospholipid mimic with specific binding recognition for macrophage scavenger receptors. J Med Chem (2012) 0.79
Platelet-activating factor involvement in thioacetamide-induced experimental liver fibrosis and cirrhosis. Dig Dis Sci (2009) 0.79
Increase in oxidative stress as measured by cerebrospinal fluid lipid peroxidation during treatment for childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol (2015) 0.77
Role of endothelium-dependent hyperpolarisation and prostacyclin in diabetes. Malays J Med Sci (2015) 0.75
Lysophosphatidylcholine, oxidized low-density lipoprotein and cardiovascular disease in Korean hemodialysis patients: analysis at 5 years of follow-up. J Korean Med Sci (2013) 0.75
Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood (1998) 7.70
Rapid neutrophil adhesion to activated endothelium mediated by GMP-140. Nature (1990) 5.17
Platelet-activating factor and related lipid mediators. Annu Rev Biochem (2000) 3.44
Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell cocultures. J Clin Invest (1995) 3.14
Endothelial cell interactions with granulocytes: tethering and signaling molecules. Immunol Today (1992) 3.06
Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils. J Cell Biol (1991) 3.05
Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells. J Clin Invest (2001) 3.01
Anti-inflammatory properties of a platelet-activating factor acetylhydrolase. Nature (1995) 2.79
Activated platelets mediate inflammatory signaling by regulated interleukin 1beta synthesis. J Cell Biol (2001) 2.75
Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. J Biol Chem (1993) 2.61
Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils. J Cell Biol (1991) 2.59
Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro. J Clin Invest (1985) 2.58
Activated platelets signal chemokine synthesis by human monocytes. J Clin Invest (1996) 2.51
Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin. Proc Natl Acad Sci U S A (1984) 2.28
Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase. J Clin Invest (1996) 2.21
Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta. Nature (1998) 2.20
Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils. Proc Natl Acad Sci U S A (1986) 2.18
Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate. J Clin Invest (1985) 2.16
Platelet-activating factor. J Biol Chem (1990) 2.13
Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation. J Clin Invest (1995) 2.06
Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3'-untranslated region. J Biol Chem (2000) 2.05
Signal-dependent translation of a regulatory protein, Bcl-3, in activated human platelets. Proc Natl Acad Sci U S A (1998) 1.97
Human plasma platelet-activating factor acetylhydrolase. Association with lipoprotein particles and role in the degradation of platelet-activating factor. J Biol Chem (1987) 1.93
Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect. Proc Natl Acad Sci U S A (1996) 1.88
Inflammatory roles of P-selectin. J Clin Invest (1993) 1.87
Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J Clin Invest (1997) 1.87
Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists. J Biol Chem (2001) 1.86
Intracellular unesterified arachidonic acid signals apoptosis. Proc Natl Acad Sci U S A (2000) 1.85
Endothelial cell-associated platelet-activating factor: a novel mechanism for signaling intercellular adhesion. J Cell Biol (1990) 1.84
Transforming growth factor-beta1 enhances Ha-ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA. J Biol Chem (2000) 1.77
Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions. J Biol Chem (1999) 1.73
Human plasma platelet-activating factor acetylhydrolase. Oxidatively fragmented phospholipids as substrates. J Biol Chem (1991) 1.71
Complications of pulmonary artery catheterization in the care of critically ill patients. A prospective study. Chest (1979) 1.68
Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein. J Clin Invest (1995) 1.66
The leukocyte integrins. J Biol Chem (2000) 1.65
Characterization of 1,2-diacylglycerol hydrolysis in human platelets. Demonstration of an arachidonoyl-monoacylglycerol intermediate. J Biol Chem (1983) 1.59
Human plasma platelet-activating factor acetylhydrolase. Purification and properties. J Biol Chem (1987) 1.55
The evolving role of platelets in inflammation. J Thromb Haemost (2003) 1.55
Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion. J Clin Invest (1988) 1.51
Diacylglycerol kinase epsilon regulates seizure susceptibility and long-term potentiation through arachidonoyl- inositol lipid signaling. Proc Natl Acad Sci U S A (2001) 1.51
Platelet-activating factor acetylhydrolases. J Biol Chem (1997) 1.51
Activation of human neutrophil phospholipase D by three separable mechanisms. FASEB J (1990) 1.50
Engagement of P-selectin glycoprotein ligand-1 enhances tyrosine phosphorylation and activates mitogen-activated protein kinases in human neutrophils. J Biol Chem (1997) 1.48
An oxidized derivative of phosphatidylcholine is a substrate for the platelet-activating factor acetylhydrolase from human plasma. J Biol Chem (1989) 1.48
Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent and -independent mitogen-activated protein kinase cascades. J Biol Chem (1996) 1.47
Neutrophil activating factor (NAF) induces polymorphonuclear leukocyte adherence to endothelial cells and to subendothelial matrix proteins. Biochem Biophys Res Commun (1989) 1.46
Molecular basis of the interaction between plasma platelet-activating factor acetylhydrolase and low density lipoprotein. J Biol Chem (1999) 1.46
Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells. J Clin Invest (1995) 1.44
Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad. J Biol Chem (1995) 1.44
Platelet-activating factor acetylhydrolase increases during macrophage differentiation. A novel mechanism that regulates accumulation of platelet-activating factor. J Biol Chem (1989) 1.42
Molecular cloning of a novel human diacylglycerol kinase highly selective for arachidonate-containing substrates. J Biol Chem (1996) 1.39
Protein synthesis by platelets: historical and new perspectives. J Thromb Haemost (2008) 1.38
Discovery of an arachidonoyl coenzyme A synthetase in human platelets. J Biol Chem (1982) 1.36
Peroxisome proliferators enhance cyclooxygenase-2 expression in epithelial cells. J Biol Chem (1999) 1.35
An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammation and endotoxin lethality. Mol Med (1995) 1.31
Molecular cloning and characterization of a novel human diacylglycerol kinase zeta. J Biol Chem (1996) 1.31
Leukocyte activation induces surface redistribution of P-selectin glycoprotein ligand-1. J Leukoc Biol (1997) 1.30
CD11b/CD18 integrin and a beta-glucan receptor act in concert to induce the synthesis of platelet-activating factor by monocytes. J Immunol (1994) 1.30
The effects of mepacrine and p-bromophenacyl bromide on arachidonic acid release in human platelets. Arch Biochem Biophys (1982) 1.29
Oxidatively fragmented phosphatidylcholines activate human neutrophils through the receptor for platelet-activating factor. J Biol Chem (1991) 1.29
Thrombin stimulates neutrophil adherence by an endothelial cell-dependent mechanism: characterization of the response and relationship to platelet-activating factor synthesis. Ann N Y Acad Sci (1986) 1.28
Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha. J Clin Invest (1997) 1.28