Published in J Med Microbiol on September 01, 1999
Molecular host-pathogen interaction in brucellosis: current understanding and future approaches to vaccine development for mice and humans. Clin Microbiol Rev (2003) 2.03
A DNA vaccine encoding lumazine synthase from Brucella abortus induces protective immunity in BALB/c mice. Infect Immun (2002) 1.11
Brucella lumazine synthase elicits a mixed Th1-Th2 immune response and reduces infection in mice challenged with Brucella abortus 544 independently of the adjuvant formulation used. Infect Immun (2003) 1.06
Evolution of vitamin B2 biosynthesis: 6,7-dimethyl-8-ribityllumazine synthases of Brucella. J Bacteriol (2006) 0.85
Human infection with M- strain of Brucella canis. Emerg Infect Dis (2004) 0.82
A polymeric protein induces specific cytotoxicity in a TLR4 dependent manner in the absence of adjuvants. PLoS One (2012) 0.80
Brucella spp. Lumazine Synthase Induces a TLR4-Mediated Protective Response against B16 Melanoma in Mice. PLoS One (2015) 0.77
Characterization of structural and immunological properties of a fusion protein between flagellin from Salmonella and lumazine synthase from Brucella. Protein Sci (2017) 0.75
Analysis of a chemical plant defense mechanism in grasses. Science (1997) 3.30
The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms. Chem Biol (1998) 3.23
Biosynthesis of isoprenoids via the non-mevalonate pathway. Cell Mol Life Sci (2004) 2.68
Terpenoid biosynthesis from 1-deoxy-D-xylulose in higher plants by intramolecular skeletal rearrangement. Proc Natl Acad Sci U S A (1997) 2.64
Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol. Proc Natl Acad Sci U S A (1999) 2.47
Studies on the biosynthesis of taxol: the taxane carbon skeleton is not of mevalonoid origin. Proc Natl Acad Sci U S A (1996) 2.45
Deoxyxylulose phosphate pathway to terpenoids. Trends Plant Sci (2001) 2.31
Biosynthesis of terpenoids: YchB protein of Escherichia coli phosphorylates the 2-hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. Proc Natl Acad Sci U S A (2000) 2.30
Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate to 2C-methyl-D-erythritol 2,4-cyclodiphosphate. Proc Natl Acad Sci U S A (2000) 2.06
Studies on the nonmevalonate pathway to terpenes: the role of the GcpE (IspG) protein. Proc Natl Acad Sci U S A (2001) 1.81
Retrobiosynthetic analysis of carbon fixation in the phototrophic eubacterium Chloroflexus aurantiacus. Eur J Biochem (1993) 1.70
13C-NMR study of autotrophic CO2 fixation pathways in the sulfur-reducing Archaebacterium Thermoproteus neutrophilus and in the phototrophic Eubacterium Chloroflexus aurantiacus. Eur J Biochem (1992) 1.67
Autotrophic CO(2) fixation by Chloroflexus aurantiacus: study of glyoxylate formation and assimilation via the 3-hydroxypropionate cycle. J Bacteriol (2001) 1.63
An optomechanical transducer in the blue light receptor phototropin from Avena sativa. Proc Natl Acad Sci U S A (2001) 1.63
Products of enzymatic reduction of benzoyl-CoA, a key reaction in anaerobic aromatic metabolism. Eur J Biochem (1993) 1.53
The non-mevalonate pathway of isoprenoids: genes, enzymes and intermediates. Curr Opin Chem Biol (2001) 1.49
Characterization of an 18-kilodalton Brucella cytoplasmic protein which appears to be a serological marker of active infection of both human and bovine brucellosis. J Clin Microbiol (1993) 1.34
Atomic structure of GTP cyclohydrolase I. Structure (1995) 1.30
Biosynthesis of riboflavin: cloning, sequencing, and expression of the gene coding for 3,4-dihydroxy-2-butanone 4-phosphate synthase of Escherichia coli. J Bacteriol (1992) 1.28
Biosynthesis of terpenoids. 2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) from Plasmodium falciparum. Eur J Biochem (2001) 1.27
Isoprenoid biosynthetic pathways as anti-infective drug targets. Biochem Soc Trans (2005) 1.26
Active site topology and reaction mechanism of GTP cyclohydrolase I. Proc Natl Acad Sci U S A (1995) 1.24
Zinc plays a key role in human and bacterial GTP cyclohydrolase I. Proc Natl Acad Sci U S A (2000) 1.24
Biosynthesis of nucleotides, flavins, and deazaflavins in Methanobacterium thermoautotrophicum. J Biol Chem (1991) 1.20
Riboflavin synthases of Bacillus subtilis. Purification and amino acid sequence of the alpha subunit. J Biol Chem (1990) 1.19
Serological follow-up of human brucellosis by measuring IgG antibodies to lipopolysaccharide and cytoplasmic proteins of Brucella species. Clin Infect Dis (1996) 1.17
Differentiation between active and inactive human brucellosis by measuring antiprotein humoral immune responses. J Clin Microbiol (1992) 1.17
Biosynthesis of riboflavin. Studies on the mechanism of L-3,4-dihydroxy-2-butanone 4-phosphate synthase. J Biol Chem (1991) 1.16
Rearrangement reactions in the biosynthesis of molybdopterin--an NMR study with multiply 13C/15N labelled precursors. Eur J Biochem (1998) 1.13
Dimethylallyl pyrophosphate is not the committed precursor of isopentenyl pyrophosphate during terpenoid biosynthesis from 1-deoxyxylulose in higher plants. Proc Natl Acad Sci U S A (1999) 1.12
Elucidation of biosynthetic pathways by retrodictive/predictive comparison of isotopomer patterns determined by NMR spectroscopy. Genet Eng (N Y) (2000) 1.12
Biosynthesis of cannabinoids. Incorporation experiments with (13)C-labeled glucoses. Eur J Biochem (2001) 1.11
Cloning, sequencing, mapping and hyperexpression of the ribC gene coding for riboflavin synthase of Escherichia coli. Eur J Biochem (1996) 1.11
Biosynthesis of riboflavin: cloning, sequencing, mapping, and expression of the gene coding for GTP cyclohydrolase II in Escherichia coli. J Bacteriol (1993) 1.11
Heavy riboflavin synthase from Bacillus subtilis. Crystal structure analysis of the icosahedral beta 60 capsid at 3.3 A resolution. J Mol Biol (1988) 1.11
Biosynthesis of terpenoids: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from tomato. Proc Natl Acad Sci U S A (2000) 1.10
Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis. J Bacteriol (1997) 1.10
High resolution dissociative electron attachment to gas phase adenine. J Chem Phys (2006) 1.09
Biosynthesis of pteridines. NMR studies on the reaction mechanisms of GTP cyclohydrolase I, pyruvoyltetrahydropterin synthase, and sepiapterin reductase. J Biol Chem (1998) 1.09
Humoral immune response against lipopolysaccharide and cytoplasmic proteins of Brucella abortus in cattle vaccinated with B. abortus S19 or experimentally infected with Yersinia enterocolitica serotype 0:9. Clin Diagn Lab Immunol (1996) 1.07
New aspects of the morphology and function of the human hip joint ligaments. Am J Anat (1991) 1.07
Biosynthesis of pteridines in Escherichia coli. Structural and mechanistic similarity of dihydroneopterin-triphosphate epimerase and dihydroneopterin aldolase. J Biol Chem (1998) 1.06
A novel pathway of aerobic benzoate catabolism in the bacteria Azoarcus evansii and Bacillus stearothermophilus. J Biol Chem (2001) 1.06
13C-NMR study of autotrophic CO2 fixation in Thermoproteus neutrophilus. Eur J Biochem (1989) 1.05
The solution structure of the N-terminal domain of riboflavin synthase. J Mol Biol (2001) 1.05
Histidine 179 mutants of GTP cyclohydrolase I catalyze the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone triphosphate. J Biol Chem (1999) 1.05
Nonaromatic products from anoxic conversion of benzoyl-CoA with benzoyl-CoA reductase and cyclohexa-1,5-diene-1-carbonyl-CoA hydratase. J Biol Chem (2000) 1.04
Biosynthesis of riboflavin. Formation of 2,5-diamino-6-hydroxy-4-(1'-D-ribitylamino)pyrimidine in a riboflavin auxotroph. J Biol Chem (1970) 1.04
The atomic structure of pentameric lumazine synthase from Saccharomyces cerevisiae at 1.85 A resolution reveals the binding mode of a phosphonate intermediate analogue. J Mol Biol (2000) 1.03
Biosynthesis of tetrahydrofolate. Sequence of GTP cyclohydrolase I from Escherichia coli. Biol Chem Hoppe Seyler (1991) 1.02
Riboflavin synthase of Escherichia coli. Effect of single amino acid substitutions on reaction rate and ligand binding properties. J Biol Chem (2001) 1.02
Auxin biosynthesis in maize kernels. Plant Physiol (2000) 1.01
The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters. EMBO J (1997) 1.01
Riboflavin synthases of Bacillus subtilis. Purification and properties. J Biol Chem (1980) 1.01
Cyclohexa-1,5-diene-1-carbonyl-CoA hydratase [corrected], an enzyme involved in anaerobic metabolism of benzoyl-CoA in the denitrifying bacterium Thauera aromatica. Eur J Biochem (1998) 1.00
Cloning and expression of the putative gene coding for GTP cyclohydrolase I from Escherichia coli. FEMS Microbiol Lett (1990) 1.00
Phosphorylation of 1-deoxy-D-xylulose by D-xylulokinase of Escherichia coli. Eur J Biochem (2001) 1.00
Urban outbreak of a Brucella melitensis infection in an Argentine family: clinical and diagnostic aspects. FEMS Immunol Med Microbiol (1994) 1.00
NIH shift in flavin-dependent monooxygenation: mechanistic studies with 2-aminobenzoyl-CoA monooxygenase/reductase. Proc Natl Acad Sci U S A (1999) 1.00
Realising the European Network of Biodosimetry (RENEB). Radiat Prot Dosimetry (2012) 0.99
Biosynthesis of riboflavin: an unusual riboflavin synthase of Methanobacterium thermoautotrophicum. J Bacteriol (1997) 0.99
Serological crossreactivity between Brucella abortus and Yersinia enterocolitica 0:9 I immunoblot analysis of the antibody response to Brucella protein antigens in bovine brucellosis. Vet Microbiol (1995) 0.99
Biosynthesis of terpenoids: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase of Arabidopsis thaliana. Proc Natl Acad Sci U S A (2000) 0.98
Studies on the 4-carbon precursor in the biosynthesis of riboflavin. Purification and properties of L-3,4-dihydroxy-2-butanone-4-phosphate synthase. J Biol Chem (1990) 0.98
Biosynthesis of riboflavin. 6,7-Dimethyl-8-ribityllumazine 5'-phosphate is not a substrate for riboflavin synthase. Biochim Biophys Acta (1978) 0.98
Biochemical and genetic classification of riboflavine deficient mutants of Saccharomyces cerevisiae. Mol Gen Genet (1969) 0.98
Retrobiosynthetic nuclear magnetic resonance analysis of amino acid biosynthesis and intermediary metabolism. Metabolic flux in developing maize kernels. Plant Physiol (2001) 0.97
[On intermediates of riboflavin biosynthesis in Saccharomyces cerevisiae]. Z Naturforsch B (1967) 0.97
Diagnosis of canine brucellosis by detection of serum antibodies against an 18 kDa cytoplasmic protein of Brucella spp. Vet Microbiol (1997) 0.97
Enzymatic synthesis of riboflavin and FMN specifically labeled with 13C in the xylene ring. Z Naturforsch C (1987) 0.96
A pentacyclic reaction intermediate of riboflavin synthase. Proc Natl Acad Sci U S A (2001) 0.96
Substrate channeling in the lumazine synthase/riboflavin synthase complex of Bacillus subtilis. J Biol Chem (1995) 0.96
Enzyme-assisted preparation of isotope-labeled 1-deoxy-d-xylulose 5-phosphate. J Org Chem (2001) 0.96
Studies on the nonmevalonate pathway of terpene biosynthesis. The role of 2C-methyl-D-erythritol 2,4-cyclodiphosphate in plants. Eur J Biochem (2001) 0.96
Control of tetrahydrobiopterin synthesis in T lymphocytes by synergistic action of interferon-gamma and interleukin-2. J Biol Chem (1990) 0.95
Biosynthesis of riboflavin. Studies on the reaction mechanism of 6,7-dimethyl-8-ribityllumazine synthase. Biochemistry (1995) 0.95
EPR, ENDOR, and TRIPLE resonance spectroscopy on the neutral flavin radical in Escherichia coli DNA photolyase. Biochemistry (1999) 0.95
Biosynthesis of 5-hydroxybenzimidazolylcobamid (factor III) in Methanobacterium thermoautotrophicum. J Biol Chem (1991) 0.95
Biosynthesis of riboflavin. Lumazine synthase of Escherichia coli. J Biol Chem (1996) 0.95
Biosynthetic precursors of deazaflavins. J Bacteriol (1992) 0.94
Discrimination of cancerous and non-cancerous cell lines by headspace-analysis with PTR-MS. Anal Bioanal Chem (2010) 0.93
Mutation in the P36 gene of Mycobacterium bovis provokes attenuation of the bacillus in a mouse model. Tuberculosis (Edinb) (2005) 0.92
Domain structure of riboflavin synthase. Eur J Biochem (2001) 0.92
Cloning, sequencing and functional studies of the gene encoding human GTP cyclohydrolase I. Gene (1996) 0.92
Biosynthesis of riboflavin: lumazine synthase and riboflavin synthase. Methods Enzymol (1997) 0.91
Heavy riboflavin synthase of Bacillus subtilis. Primary structure of the beta subunit. J Biol Chem (1987) 0.91
Heavy riboflavin synthase from Bacillus subtilis. Methods Enzymol (1986) 0.91
Engineering of a polymeric bacterial protein as a scaffold for the multiple display of peptides. Proteins (2004) 0.91
Retrobiosynthetic NMR studies with 13C-labeled glucose. Formation of gallic acid in plants and fungi. J Biol Chem (1997) 0.91
Formation of tight junctions in epithelial cells. I. Induction by proteases in a human colon carcinoma cell line. Exp Cell Res (1985) 0.90
Carbon-13 and nitrogen-15 nuclear-magnetic-resonance investigation on Desulfovibrio vulgaris flavodoxin. Eur J Biochem (1985) 0.90
Use of enrofloxacin in the treatment of canine brucellosis in a dog kennel (clinical trial). Theriogenology (2006) 0.90
Ionization of doped helium nanodroplets: complexes of C60 with water clusters. J Chem Phys (2010) 0.90
Biosynthesis of riboflavin: mechanism of formation of the ribitylamino linkage. Biochemistry (1988) 0.89