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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31-q33. Nat Genet 1995 2.93
2 The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene. Am J Hum Genet 1999 2.17
3 Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis. Tissue Antigens 2007 1.77
4 Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes. Diabetologia 2008 1.61
5 Evidence by allelic association-dependent methods for a type 1 diabetes polygene (IDDM6) on chromosome 18q21. Hum Mol Genet 1997 1.32
6 A gene telomeric of the HLA class I region is involved in predisposition to both type 1 diabetes and coeliac disease. Tissue Antigens 1999 1.22
7 HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection. Diabetes 1997 1.22
8 Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases. Diabetes 2001 1.17
9 Polymorphic analysis of the human MHC-linked heat shock protein 70 (HSP70-2) and HSP70-Hom genes in insulin-dependent diabetes mellitus (IDDM). Scand J Immunol 1993 1.12
10 Longitudinal observation of enterovirus and adenovirus in stool samples from Norwegian infants with the highest genetic risk of type 1 diabetes. J Clin Virol 2006 1.11
11 Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type 1 (insulin-dependent) diabetes mellitus. Diabetologia 1993 1.11
12 Genetic susceptibility markers in Danish patients with type 1 (insulin-dependent) diabetes--evidence for polygenicity in man. Danish Study Group of Diabetes in Childhood. Autoimmunity 1994 1.06
13 Evidence for a type 1 diabetes susceptibility locus (IDDM10) on human chromosome 10p11-q11. Hum Mol Genet 1997 1.01
14 Role of HLA genes in predisposition to develop insulin-dependent diabetes mellitus. Ann Med 1992 0.97
15 HLA-DQw3.1 and DQw3.2 associated exon polymorphisms detected by oligonucleotide probes. Tissue Antigens 1988 0.96
16 No difference in the parental origin of susceptibility HLA class II haplotypes among Norwegian patients with insulin-dependent diabetes mellitus. Am J Hum Genet 1995 0.94
17 HLA class II alleles and heterogeneity of juvenile rheumatoid arthritis. DRB1*0101 may define a novel subset of the disease. Arthritis Rheum 1993 0.89
18 Type 1 diabetes mellitus in Czech children diagnosed in 1990-1997: a significant increase in incidence and male predominance in the age group 0-4 years. Collaborators of the Czech Childhood Diabetes Registry. Diabet Med 2000 0.88
19 Susceptibility to develop celiac disease is primarily associated with HLA-DQ alleles. Hum Immunol 1990 0.88
20 Insulin gene region-encoded susceptibility to IDDM maps upstream of the insulin gene. Diabetes 1995 0.88
21 HLA associations in insulin-dependent diabetes mellitus: no independent association to particular DP genes. Hum Immunol 1997 0.87
22 Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families. Genes Immun 2008 0.87
23 Coding region polymorphisms of human T-cell receptor V beta 6.9 and V beta 21.4. Scand J Immunol 1992 0.86
24 No independent associations of LMP2 and LMP7 polymorphisms with susceptibility to develop IDDM. Diabetes 1997 0.86
25 The FCRL3 -169T>C polymorphism is associated with rheumatoid arthritis and shows suggestive evidence of involvement with juvenile idiopathic arthritis in a Scandinavian panel of autoimmune diseases. Ann Rheum Dis 2007 0.85
26 HLA-DQA1 and HLA-DQB1 genes may jointly determine susceptibility to develop multiple sclerosis. Hum Immunol 1991 0.85
27 Hardy-Weinberg testing for HLA class II (DRB1, DQA1, DQB1, and DPB1) loci in 26 human ethnic groups. Tissue Antigens 1999 0.84
28 IDDM susceptibility associated with polymorphisms in the insulin gene region. A study of blacks, Caucasians and orientals. Diabetologia 1994 0.83
29 Dw14 is a Dw4-independent risk factor for rheumatoid arthritis among Norwegians. Tissue Antigens 1992 0.82
30 Genetic and functional evaluation of an interleukin-12 polymorphism (IDDM18) in families with type 1 diabetes. J Med Genet 2004 0.81
31 Testing the possible negative association of type 1 diabetes and atopic disease by analysis of the interleukin 4 receptor gene. Genes Immun 2003 0.81
32 HLA antigens and cervical carcinoma. Nature 1992 0.81
33 Seronegative and weakly seropositive rheumatoid arthritis differ from clearly seropositive rheumatoid arthritis in HLA class II associations. J Rheumatol 1994 0.80
34 HLA-DR-DQ haplotype frequencies in a Norwegian population. Transplant Proc 1992 0.79
35 Screening for the IDDM high-risk genotype. A rapid microtitre plate method using serum as source of DNA. Tissue Antigens 2000 0.79
36 T cells recognizing an HLA-DQ alpha beta heterodimer encoded in cis by the DR4DQw4 haplotype and in trans by DR4DQw8/DRw8DQw4 heterozygous cells. Hum Immunol 1991 0.79
37 DQA1 and DQB1 genes in patients with squamous cell carcinoma of the cervix: relationship to human papillomavirus infection and prognosis. Cancer Epidemiol Biomarkers Prev 1994 0.79
38 Does HLA genotype influence the relative risk of Type 1 diabetes conferred by dietary factors? Diabet Med 2002 0.79
39 HLA-DR1 and rheumatoid arthritis in Israeli Jews: sequencing reveals that DRB1*0102 is the predominant HLA-DR1 subtype. Tissue Antigens 1993 0.79
40 The relation between size at birth and risk of type 1 diabetes is not influenced by adjustment for the insulin gene (-23HphI) polymorphism or HLA-DQ genotype. Diabetologia 2006 0.77
41 Genetic markers for glutamic acid decarboxylase do not predict insulin-dependent diabetes mellitus in pairs of affected siblings. The Danish Study Group of Diabetes in Childhood. Hum Genet 1997 0.77
42 An increased risk of cervical intra-epithelial neoplasia grade II-III among human papillomavirus positive patients with the HLA-DQA1*0102-DQB1*0602 haplotype: a population-based case-control study of Norwegian women. Int J Cancer 1998 0.77
43 Myasthenia gravis patients with thymus hyperplasia and myasthenia gravis patients with thymoma display different HLA associations. Tissue Antigens 1991 0.77
44 Association between the HLA DQB1*0301 gene and human papillomavirus infection in high-grade cervical intraepithelial neoplasia. Int J Gynecol Pathol 1999 0.76
45 HLA associations in type 1 diabetes among patients not carrying high-risk DR3-DQ2 or DR4-DQ8 haplotypes. Tissue Antigens 1999 0.76
46 Polymorphism of human major histocompatibility complex-encoded transporter associated with antigen processing (TAP) genes and susceptibility to juvenile rheumatoid arthritis. Hum Immunol 1994 0.75
47 Antigen-specific T cells restricted by HLA-DQw8: importance of residue 57 of the DQ beta chain. Hum Immunol 1990 0.75
48 [Can type 1 diabetes be prevented?]. Tidsskr Nor Laegeforen 1992 0.75
49 HLA-DRB1, -DQA1, -DQB1, -DPA1 and -DPB1 genes in Japanese multiple sclerosis patients. Tissue Antigens 1991 0.75
50 [Gene technology in immunologic research, diagnosis and treatment]. Tidsskr Nor Laegeforen 1989 0.75
51 [Genetic and immunologic risks for development of type 1 diabetes--experiences from an intervention trial]. Tidsskr Nor Laegeforen 2000 0.75
52 HLA-DQ antigens and DQ beta amino acid 57 of Japanese patients with insulin-dependent diabetes mellitus: detection of a DRw8DQw8 haplotype. Tissue Antigens 1989 0.75
53 Molecular basis and functional importance of some disease-associated HLA polymorphisms. Tissue Antigens 1989 0.75
54 Insulin dependent diabetes mellitus susceptibility or protection may be determined by certain HLA-DQ molecules. Baillieres Clin Endocrinol Metab 1991 0.75
55 Diabetes-associated HLA-DQ genes and birth weight. Diabetes 2001 0.75
56 Insulin autoimmune syndrome; HLA genes may be a marker of disease heterogeneity. Autoimmunity 1993 0.75