Published in FASEB J on October 01, 1999
Transglutaminases: nature's biological glues. Biochem J (2002) 3.42
GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis. Proc Natl Acad Sci U S A (2006) 2.08
Two-way traffic on the road to plasma membrane repair. Trends Cell Biol (2008) 1.66
Pathways for aberrant angiogenesis in pancreatic cancer. Mol Cancer (2003) 1.61
Transglutaminase 2 inhibitors and their therapeutic role in disease states. Pharmacol Ther (2007) 1.60
A novel role for erythropoietin during fibrin-induced wound-healing response. Am J Pathol (2003) 1.26
Dextran hydrogel scaffolds enhance angiogenic responses and promote complete skin regeneration during burn wound healing. Proc Natl Acad Sci U S A (2011) 1.24
Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling. J Biol Chem (2008) 1.21
Increased TG2 expression can result in induction of transforming growth factor beta1, causing increased synthesis and deposition of matrix proteins, which can be regulated by nitric oxide. J Biol Chem (2009) 1.20
Proteolysis of cell-surface tissue transglutaminase by matrix metalloproteinase-2 contributes to the adhesive defect and matrix abnormalities in thrombospondin-2-null fibroblasts and mice. Am J Pathol (2005) 1.17
Heparan sulfate proteoglycans are receptors for the cell-surface trafficking and biological activity of transglutaminase-2. J Biol Chem (2009) 1.17
Roles of transglutaminases in cardiac and vascular diseases. Front Biosci (2007) 1.07
Regulation of platelet-derived growth factor receptor function by integrin-associated cell surface transglutaminase. J Biol Chem (2009) 1.03
Coeliac disease-specific autoantibodies targeted against transglutaminase 2 disturb angiogenesis. Clin Exp Immunol (2008) 1.02
Role of transglutaminase 2 in celiac disease pathogenesis. Semin Immunopathol (2012) 0.98
Antibodies in celiac disease: implications beyond diagnostics. Cell Mol Immunol (2011) 0.98
Transglutaminase-2: a new endostatin partner in the extracellular matrix of endothelial cells. Biochem J (2010) 0.94
Epidermal transglutaminase (TGase 3) is required for proper hair development, but not the formation of the epidermal barrier. PLoS One (2012) 0.94
Reactivity of the N-terminal region of fibronectin protein to transglutaminase 2 and factor XIIIA. J Biol Chem (2011) 0.92
Facilitated wound healing by activation of the Transglutaminase 1 gene. Am J Pathol (2000) 0.91
Crystal structure of transglutaminase 2 with GTP complex and amino acid sequence evidence of evolution of GTP binding site. PLoS One (2014) 0.91
Tissue transglutaminase, protein cross-linking and Alzheimer's disease: review and views. Int J Clin Exp Pathol (2008) 0.90
β cell ER stress and the implications for immunogenicity in type 1 diabetes. Front Cell Dev Biol (2015) 0.90
Transglutaminase 5 is regulated by guanine-adenine nucleotides. Biochem J (2004) 0.89
Extracellular tissue transglutaminase activates noncanonical NF-κB signaling and promotes metastasis in ovarian cancer. Neoplasia (2013) 0.88
Functional studies of a novel oncogene TGM3 in human esophageal squamous cell carcinoma. World J Gastroenterol (2006) 0.85
Mucosal tissue transglutaminase expression in celiac disease. J Cell Mol Med (2008) 0.85
A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis. Cell Death Dis (2013) 0.84
Wound healing monitoring using near infrared fluorescent fibrinogen. Biomed Opt Express (2010) 0.81
Propionyl-L-Carnitine Enhances Wound Healing and Counteracts Microvascular Endothelial Cell Dysfunction. PLoS One (2015) 0.80
Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death. Cell Death Dis (2016) 0.80
Endothelial apoptotic activity of angiocidin is dependent on its polyubiquitin binding activity. Br J Cancer (2005) 0.79
Transglutaminases (TGs) in ocular and periocular tissues: effect of muscarinic agents on TGs in scleral fibroblasts. PLoS One (2011) 0.78
Transglutaminse 2 and EGGL, the protein cross-link formed by transglutaminse 2, as therapeutic targets for disabilities of old age. Rejuvenation Res (2013) 0.75
Accelerated Burn Wound Closure in Mice with a New Formula Based on Traditional Medicine. Iran Red Crescent Med J (2016) 0.75
Retracted Elevated expression of isopeptide bond cross-links contributes to fibrosis in scleroderma and the healing wounds of tight skin mice. Wound Repair Regen (2009) 0.75
Crystallization and preliminary X-ray crystallographic studies of transglutaminase 2 in complex with Ca2+. Acta Crystallogr F Struct Biol Commun (2014) 0.75
The time course of cytokine expressions plays a determining role in faster healing of intestinal and colonic anastomatic wounds. Saudi J Gastroenterol (2015) 0.75
Antagonistic enzymes may generate alternate phase transitions leading to ephemeral gels. Biophys J (2007) 0.75
The functional relationship between transglutaminase 2 and transforming growth factor β1 in the regulation of angiogenesis and endothelial-mesenchymal transition. Cell Death Dis (2017) 0.75
[Chemically modified, ultra-hydrophilic titanium implant surfaces]. Mund Kiefer Gesichtschir (2007) 0.75
The effect of bone marrow concentrate and hyperbaric oxygen therapy on bone repair. J Mater Sci Mater Med (2015) 0.75
Immunohistochemical characteristics of regenerated bone after surgical therapy of advanced ligature-induced peri-implantitis defects. Clin Oral Investig (2013) 0.75
The proteomic profile of a mouse model of proliferative vitreoretinopathy. FEBS Open Bio (2017) 0.75
Environmental Factors Contribute to β Cell Endoplasmic Reticulum Stress and Neo-Antigen Formation in Type 1 Diabetes. Front Endocrinol (Lausanne) (2017) 0.75
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res (1996) 4.98
Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int J Radiat Oncol Biol Phys (1997) 4.55
Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models. J Natl Cancer Inst (2000) 4.09
Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size. Cancer Res (2000) 3.10
A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model. Cancer Res (2000) 2.99
Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer. Int J Radiat Oncol Biol Phys (2001) 2.59
Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues. Circ Res (1997) 2.58
Transcriptional response to hypoxia in human tumors. J Natl Cancer Inst (2001) 2.44
Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome. Radiother Oncol (1999) 2.25
The multifaceted roles of nitric oxide in cancer. Carcinogenesis (1998) 2.19
Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release. Cancer Res (2000) 2.17
Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature. Cancer Res (2001) 2.08
Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma. Cancer Res (1996) 2.07
Hyperbaric oxygen improves tumor radiation response significantly more than carbogen/nicotinamide. Radiat Res (1997) 2.02
The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors. Adv Drug Deliv Rev (2001) 2.01
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2. Proc Natl Acad Sci U S A (1998) 1.93
Extravascular fibrin formation and dissolution in synovial tissue of patients with osteoarthritis and rheumatoid arthritis. Arthritis Rheum (1991) 1.80
Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability. Cancer Res (2001) 1.75
Analysis of oxygen transport to tumor tissue by microvascular networks. Int J Radiat Oncol Biol Phys (1993) 1.73
Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue. Cancer Res (1993) 1.69
Noninvasive visualization of tumors in rodent dorsal skin window chambers. Nat Biotechnol (1999) 1.69
Analysis of the effects of oxygen supply and demand on hypoxic fraction in tumors. Acta Oncol (1995) 1.66
Characterization of the effects of cultured vascular cells on the activation of blood coagulation. Blood (1983) 1.63
Identification of a guanosine triphosphate-binding site on guinea pig liver transglutaminase. Role of GTP and calcium ions in modulating activity. J Biol Chem (1987) 1.58
Pain assessment in infants and children. Pediatr Clin North Am (2000) 1.55
Proteins exposed on the surface of mammalian membranes. Biochemistry (1972) 1.51
Reversible shear-mediated platelet dysfunction during cardiac surgery as assessed by the PFA-100 platelet function analyzer. Blood Coagul Fibrinolysis (2001) 1.50
Diminished leukocyte-endothelium interaction in tumor microvessels. Cancer Res (1992) 1.47
Drug targeting using thermally responsive polymers and local hyperthermia. J Control Release (2001) 1.47
Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents. Am J Physiol Heart Circ Physiol (2001) 1.47
Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia. Cancer Res (2001) 1.45
Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor. Cell Growth Differ (1998) 1.44
Epidural anesthesia and analgesia: implications for perioperative coagulability. Anesth Analg (1991) 1.42
Radiation-induced hypoxia may perpetuate late normal tissue injury. Int J Radiat Oncol Biol Phys (2001) 1.42
HIF-1 and tumour radiosensitivity. Br J Cancer (2006) 1.41
Hyperthermia and liposomes. Int J Hyperthermia (1999) 1.39
Circumventing tamoxifen resistance in breast cancers using antiestrogens that induce unique conformational changes in the estrogen receptor. Cancer Res (2001) 1.38
Tumor oxygenation: a matter of supply and demand. Anticancer Res (1996) 1.38
Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle in rats. Am J Physiol (1999) 1.36
Inhibition of the relative movement of actin and myosin by caldesmon and calponin. J Biol Chem (1992) 1.36
Thermosensitive liposomes: extravasation and release of contents in tumor microvascular networks. Int J Radiat Oncol Biol Phys (1996) 1.32
Available volume fraction of macromolecules in the extravascular space of a fibrosarcoma: implications for drug delivery. Cancer Res (1999) 1.32
Radiation therapy and hyperthermia improve the oxygenation of human soft tissue sarcomas. Cancer Res (1996) 1.28
Effective tumor therapy with plasmid-encoded cytokines combined with in vivo electroporation. Cancer Res (2001) 1.27
Treatment with Imatinib in NSCLC is associated with decrease of phosphorylated PDGFR-beta and VEGF expression, decrease in interstitial fluid pressure and improvement of oxygenation. Br J Cancer (2006) 1.25
In vivo BOLD contrast MRI mapping of subcutaneous vascular function and maturation: validation by intravital microscopy. Magn Reson Med (2001) 1.24
Patterns and variability of tumor oxygenation in human soft tissue sarcomas, cervical carcinomas, and lymph node metastases. Int J Radiat Oncol Biol Phys (1995) 1.21
Calcium regulates S-nitrosylation, denitrosylation, and activity of tissue transglutaminase. Biochemistry (2001) 1.20
A microtiter plate transglutaminase assay utilizing 5-(biotinamido)pentylamine as substrate. Anal Biochem (1992) 1.19
Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells. Oncogene (2011) 1.17
A comparison of tumor and normal tissue microvascular hematocrits and red cell fluxes in a rat window chamber model. Int J Radiat Oncol Biol Phys (1993) 1.15
Hyperthermia increases accumulation of technetium-99m-labeled liposomes in feline sarcomas. Clin Cancer Res (2000) 1.13
The mechanisms by which hyperbaric oxygen and carbogen improve tumour oxygenation. Br J Cancer (1995) 1.13
Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways. J Biol Chem (1987) 1.13
Measurement of material extravasation in microvascular networks using fluorescence video-microscopy. Microvasc Res (1993) 1.12
Early wound healing exhibits cytokine surge without evidence of hypoxia. Ann Surg (2000) 1.12
Cholesterol and atheroma lipids activate complement and stimulate granulocytes. A possible mechanism for amplification of ischemic injury in atherosclerotic states. J Lab Clin Med (1981) 1.11
The zymogen forms of blood coagulation factor XIII bind specifically to fibrinogen. J Biol Chem (1982) 1.10
Biological and clinical aspects of hyperthermia in cancer therapy. Am J Clin Oncol (1988) 1.09
Use of whole body hyperthermia as a method to heat inaccessible tumours uniformly: a phase III trial in canine brain masses. Int J Hyperthermia (1999) 1.09
Sensitivity of hyperthermia trial outcomes to temperature and time: implications for thermal goals of treatment. Int J Radiat Oncol Biol Phys (1993) 1.08
Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment. Int J Radiat Oncol Biol Phys (2000) 1.08
Tumor necrosis factor induces tissue factor-like activity in human leukemia cell line U937 and peripheral blood monocytes. Blood (1988) 1.08
Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model. Int J Radiat Oncol Biol Phys (2001) 1.08
Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts. Br J Cancer (2007) 1.08
Pretreatment oxygenation profiles of human soft tissue sarcomas. Int J Radiat Oncol Biol Phys (1994) 1.04
Regulation of human tissue transglutaminase function by magnesium-nucleotide complexes. Identification of distinct binding sites for Mg-GTP and Mg-ATP. J Biol Chem (1998) 1.04
b-chains prevent the proteolytic inactivation of the a-chains of plasma factor XIII. Biochim Biophys Acta (1988) 1.03
C-terminal deletion of human tissue transglutaminase enhances magnesium-dependent GTP/ATPase activity. J Biol Chem (1996) 1.02
Monitoring of neoadjuvant therapy response of soft-tissue and musculoskeletal sarcoma using fluorine-18-FDG PET. J Nucl Med (1996) 1.02
Electrophoretic study of the polypeptides from surface membranes of mammalian cells. Biochemistry (1972) 1.02
Tamoxifen inhibits angiogenesis in estrogen receptor-negative animal models. Clin Cancer Res (2000) 1.02
Localization of tissue transglutaminase in human carotid and coronary artery atherosclerosis: implications for plaque stability and progression. Lab Invest (2001) 1.01
Systemic vector leakage and transgene expression by intratumorally injected recombinant adenovirus vectors. Clin Cancer Res (2001) 1.00
Theoretical simulation of oxygen transport to tumors by three-dimensional networks of microvessels. Adv Exp Med Biol (1998) 1.00
The relationship between intracellular and extracellular pH in spontaneous canine tumors. Clin Cancer Res (2000) 1.00
Simultaneous measurement of liposome extravasation and content release in tumors. Microcirculation (1997) 0.99
Using units of CEM 43 degrees C T90, local hyperthermia thermal dose can be delivered as prescribed. Int J Hyperthermia (2001) 0.98
Fragment D-dimer levels: an objective marker of vaso-occlusive crisis and other complications of sickle cell disease. Blood (1986) 0.98
Variability in blood flow and pO2 in tumors in response to carbogen breathing. Int J Radiat Oncol Biol Phys (1998) 0.97
Measurement of plasma fibrin D-dimer levels with the use of a monoclonal antibody coupled to latex beads. Am J Clin Pathol (1987) 0.97
Combined external beam irradiation and external regional hyperthermia for locally advanced adenocarcinoma of the prostate. Int J Radiat Oncol Biol Phys (1997) 0.96
Heat-induced gene expression as a novel targeted cancer gene therapy strategy. Cancer Res (2000) 0.96
Seroepidemiological survey of hepatitis E in Hong Kong by recombinant-based enzyme immunoassays. Lancet (1992) 0.96
Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomas. Int J Hyperthermia (2006) 0.96
Correction of hypoprothrombinemia by immunosuppressive treatment of the lupus anticoagulant-hypoprothrombinemia syndrome. Am J Med (1987) 0.95
Vitronectin is a substrate for transglutaminases. Biochem Biophys Res Commun (1988) 0.95
Analysis of the heterogeneity of pO2 dynamics during photodynamic therapy with verteporfin. Photochem Photobiol (2001) 0.94
Human recombinant erythropoietin (rEpo) has no effect on tumour growth or angiogenesis. Br J Cancer (2005) 0.94
Tissue transglutaminase expression in human breast cancer. Lab Invest (1996) 0.94
Carbonic anhydrase IX is a predictive marker of doxorubicin resistance in early-stage breast cancer independent of HER2 and TOP2A amplification. Br J Cancer (2012) 0.93
β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression. Oncogene (2011) 0.93