Transglutaminase-2: a new endostatin partner in the extracellular matrix of endothelial cells.

PubWeight™: 0.94‹?›

🔗 View Article (PMC 2876729)

Published in Biochem J on April 14, 2010

Authors

Clément Faye1, Antonio Inforzato, Marine Bignon, Daniel J Hartmann, Laurent Muller, Lionel Ballut, Bjorn R Olsen, Anthony J Day, Sylvie Ricard-Blum

Author Affiliations

1: Institut de Biologie et Chimie des Protéines, UMR Centre National de la Recherche Scientifique, University Lyon, France.

Articles citing this

The collagen family. Cold Spring Harb Perspect Biol (2011) 2.10

Extracellular TG2: emerging functions and regulation. FEBS J (2011) 1.35

Cellular functions of tissue transglutaminase. Int Rev Cell Mol Biol (2012) 1.27

Cysteine cathepsins S and L modulate anti-angiogenic activities of human endostatin. J Biol Chem (2011) 0.87

A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis. Cell Death Dis (2013) 0.84

Endostatin's emerging roles in angiogenesis, lymphangiogenesis, disease, and clinical applications. Biochim Biophys Acta (2015) 0.84

Target-derived matricryptins organize cerebellar synapse formation through α3β1 integrins. Cell Rep (2012) 0.84

Inhibition of allergic inflammation by supplementation with 5-hydroxytryptophan. Am J Physiol Lung Cell Mol Physiol (2012) 0.80

Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death. Cell Death Dis (2016) 0.80

Fibroblast-endothelial partners for vascularization strategies in tissue engineering. Tissue Eng Part A (2014) 0.78

Tissue Transglutaminase Mediated Tumor-Stroma Interaction Promotes Pancreatic Cancer Progression. Clin Cancer Res (2015) 0.77

Biglycan potentially regulates angiogenesis during fracture repair by altering expression and function of endostatin. Matrix Biol (2016) 0.77

Large-scale investigation of Leishmania interaction networks with host extracellular matrix by surface plasmon resonance imaging. Infect Immun (2013) 0.76

Regulation of allergic lung inflammation by endothelial cell transglutaminase 2. Am J Physiol Lung Cell Mol Physiol (2015) 0.75

Interplay between transglutaminases and heparan sulphate in progressive renal scarring. Sci Rep (2016) 0.75

Endostatin and transglutaminase 2 are involved in fibrosis of the aging kidney. Kidney Int (2016) 0.75

Articles cited by this

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3. Nature (2008) 7.10

Transglutaminases: crosslinking enzymes with pleiotropic functions. Nat Rev Mol Cell Biol (2003) 6.05

Transglutaminases: nature's biological glues. Biochem J (2002) 3.42

Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin. J Cell Biol (2000) 2.86

Antiangiogenesis in cancer therapy--endostatin and its mechanisms of action. Exp Cell Res (2005) 2.62

Transglutaminase 2 undergoes a large conformational change upon activation. PLoS Biol (2007) 2.53

Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins. Proc Natl Acad Sci U S A (2003) 2.28

Interaction of endostatin with integrins implicated in angiogenesis. Proc Natl Acad Sci U S A (2001) 2.19

Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1. J Biol Chem (2002) 1.98

Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase. Cancer Res (2000) 1.70

Extracellular transglutaminase 2 is catalytically inactive, but is transiently activated upon tissue injury. PLoS One (2008) 1.67

Identification of a guanosine triphosphate-binding site on guinea pig liver transglutaminase. Role of GTP and calcium ions in modulating activity. J Biol Chem (1987) 1.58

Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process. J Biol Chem (2002) 1.57

Tissue transglutaminase is expressed, active, and directly involved in rat dermal wound healing and angiogenesis. FASEB J (1999) 1.53

Cell surface glypicans are low-affinity endostatin receptors. Mol Cell (2001) 1.51

Transglutaminase 2 cross-linking of matrix proteins: biological significance and medical applications. Amino Acids (2008) 1.47

Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin. EMBO J (1999) 1.38

Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization. J Biol Chem (1991) 1.32

Molecular interplay between endostatin, integrins, and heparan sulfate. J Biol Chem (2009) 1.25

Matrix changes induced by transglutaminase 2 lead to inhibition of angiogenesis and tumor growth. Cell Death Differ (2005) 1.17

Heparan sulfate proteoglycans are receptors for the cell-surface trafficking and biological activity of transglutaminase-2. J Biol Chem (2009) 1.17

Endostatin regulates endothelial cell adhesion and cytoskeletal organization. Cancer Res (2002) 1.15

Characterization of endostatin binding to heparin and heparan sulfate by surface plasmon resonance and molecular modeling: role of divalent cations. J Biol Chem (2003) 1.07

Complex formation between tissue transglutaminase II (tTG) and vascular endothelial growth factor receptor 2 (VEGFR-2): proposed mechanism for modulation of endothelial cell response to VEGF. Exp Cell Res (2006) 1.06

Transglutaminase-catalyzed cross-linking of fibrils of collagen V/XI in A204 rhabdomyosarcoma cells. Biochemistry (1995) 1.04

Transglutaminase induces protofibril-like amyloid beta-protein assemblies that are protease-resistant and inhibit long-term potentiation. J Biol Chem (2008) 1.01

Identification of a substrate site for liver transglutaminase on the aminopropeptide of type III collagen. J Biol Chem (1987) 0.99

A high risk of occurrence of sporadic breast cancer in individuals with the 104NN polymorphism of the COL18A1 gene. Breast Cancer Res Treat (2006) 0.99

Cross linking to tissue transglutaminase and collagen favours gliadin toxicity in coeliac disease. Gut (2005) 0.98

The first draft of the endostatin interaction network. J Biol Chem (2009) 0.98

Molecular mechanisms and therapeutic development of angiogenesis inhibitors. Adv Cancer Res (2008) 0.97

Transglutaminases and transglutaminase-catalyzed cross-links colocalize with the pathological lesions in Alzheimer's disease brain. Brain Pathol (2008) 0.96

Tissue transglutaminase is an important player at the surface of human endothelial cells: evidence for its externalization and its colocalization with the beta(1) integrin. Exp Cell Res (1999) 0.96

Endostatin binds to the catalytic domain of matrix metalloproteinase-2. FEBS Lett (2002) 0.95

Cell-surface-associated tissue transglutaminase is a target of MMP-2 proteolysis. Biochemistry (2004) 0.94

Bovine aortic endothelial cell transglutaminase. Enzyme characterization and regulation of activity. Biochem J (1989) 0.93

Tissue transglutaminase is expressed as a host response to tumor invasion and inhibits tumor growth. Lab Invest (1999) 0.91

Aberrant neuronal and paracellular deposition of endostatin in brains of patients with Alzheimer's disease. J Neurosci (2002) 0.91

Tissue transglutaminase, protein cross-linking and Alzheimer's disease: review and views. Int J Clin Exp Pathol (2008) 0.90

Endostatin overexpression specifically in the lens and skin leads to cataract and ultrastructural alterations in basement membranes. Am J Pathol (2005) 0.89

Immunohistochemical demonstration of tissue transglutaminase in amyloid plaques. Acta Neuropathol (1998) 0.88

The Differential Effects of R580A Mutation on Transamidation and GTP Binding Activity of Rat and Human Type 2 Transglutaminase. Int J Clin Exp Med (2008) 0.88

A key role for Toll-like receptor-3 in disrupting the hemostasis balance on endothelial cells. Blood (2008) 0.87

Hypoxia-induced increase of endostatin in murine aorta and lung. Histochem Cell Biol (2006) 0.86

Interaction with heparin protects tissue transglutaminase against inactivation by heating and by proteolysis. Biochimie (2005) 0.85

Analysis of transglutaminase protein substrates by functional proteomics. Protein Sci (2003) 0.83

Endostatin/collagen XVIII accumulates in patients with traumatic brain injury. J Neurotrauma (2006) 0.79

D104N polymorphism in endostatin, an angiogenesis inhibitor, in acute and chronic myeloid leukaemia. Leuk Res (2006) 0.79

Articles by these authors

PSICQUIC and PSISCORE: accessing and scoring molecular interactions. Nat Methods (2011) 5.01

Conversion of vascular endothelial cells into multipotent stem-like cells. Nat Med (2010) 4.88

The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases. Nucleic Acids Res (2013) 4.39

Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma. Nat Med (2008) 3.98

Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA. Science (2006) 3.60

An intervention to decrease complications related to endotracheal intubation in the intensive care unit: a prospective, multiple-center study. Intensive Care Med (2009) 3.24

Protein interaction data curation: the International Molecular Exchange (IMEx) consortium. Nat Methods (2012) 3.17

Genetic PTX3 deficiency and aspergillosis in stem-cell transplantation. N Engl J Med (2014) 3.08

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nat Cell Biol (2008) 2.85

Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3. Mol Biol Cell (2008) 2.78

Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation. J Clin Invest (2012) 2.58

Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development (2002) 2.57

Neuronal loss and brain atrophy in mice lacking cathepsins B and L. Proc Natl Acad Sci U S A (2002) 2.54

VEGFA is necessary for chondrocyte survival during bone development. Development (2004) 2.54

Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function. Am J Pathol (2005) 2.38

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity. Nat Struct Mol Biol (2007) 2.30

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest (2008) 2.29

Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice. Cell (2007) 2.18

Impaired cumulus mucification and female sterility in tumor necrosis factor-induced protein-6 deficient mice. Development (2003) 2.16

Lack of collagen XVIII/endostatin results in eye abnormalities. EMBO J (2002) 2.13

Ebola virus matrix protein VP40 interaction with human cellular factors Tsg101 and Nedd4. J Mol Biol (2003) 2.11

Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation. Curr Biol (2010) 2.08

Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis. Arthritis Rheum (2007) 2.07

Hyaluronan and homeostasis: a balancing act. J Biol Chem (2001) 2.03

Structural basis for complement factor H linked age-related macular degeneration. J Exp Med (2007) 2.02

High density lipoprotein inhibits hepatitis C virus-neutralizing antibodies by stimulating cell entry via activation of the scavenger receptor BI. J Biol Chem (2006) 2.02

TSG-6: a multifunctional protein associated with inflammation. J Cell Sci (2003) 1.97

MatrixDB, a database focused on extracellular protein-protein and protein-carbohydrate interactions. Bioinformatics (2009) 1.96

Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling. Exp Cell Res (2005) 1.92

The genetic basis for skeletal diseases. Nature (2003) 1.92

MatrixDB, the extracellular matrix interaction database. Nucleic Acids Res (2010) 1.79

His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form. J Biol Chem (2006) 1.79

Multiple roles of vascular endothelial growth factor (VEGF) in skeletal development, growth, and repair. Curr Top Dev Biol (2005) 1.75

Extracellular matrix-bound angiopoietin-like 4 inhibits endothelial cell adhesion, migration, and sprouting and alters actin cytoskeleton. Circ Res (2006) 1.73

PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization. Development (2004) 1.68

Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations ("glomangiomas"). Am J Hum Genet (2002) 1.66

Knobloch syndrome: novel mutations in COL18A1, evidence for genetic heterogeneity, and a functionally impaired polymorphism in endostatin. Hum Mutat (2004) 1.61

Editorial: Journal of negative results in biomedicine. J Negat Results Biomed (2002) 1.58

Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development. Development (2004) 1.58

Localization of collagen XVIII and the endostatin portion of collagen XVIII in aged human control eyes and eyes with age-related macular degeneration. Invest Ophthalmol Vis Sci (2004) 1.56

FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis. J Cell Biol (2008) 1.53

Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice. J Biol Chem (2004) 1.53

Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney. EMBO J (2003) 1.53

Structures of the Cd44-hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction. Nat Struct Mol Biol (2007) 1.51

Characterization of complexes formed between TSG-6 and inter-alpha-inhibitor that act as intermediates in the covalent transfer of heavy chains onto hyaluronan. J Biol Chem (2005) 1.51

The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells. J Biol Chem (2007) 1.51

Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma. Hypertension (2009) 1.48

TSG-6 modulates the interaction between hyaluronan and cell surface CD44. J Biol Chem (2004) 1.48

Respiratory variations of inferior vena cava diameter to predict fluid responsiveness in spontaneously breathing patients with acute circulatory failure: need for a cautious use. Crit Care (2012) 1.48

The role of backscattering in SHG tissue imaging. Biophys J (2007) 1.43

Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression. Cancer Res (2004) 1.42

Cherubism: best clinical practice. Orphanet J Rare Dis (2012) 1.42

Physiological role of collagen XVIII and endostatin. FASEB J (2005) 1.40

The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner. J Biol Chem (2002) 1.39

Structural basis of dynamic glycine receptor clustering by gephyrin. EMBO J (2004) 1.39

Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44. Mol Cell (2004) 1.38

Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina. J Biol Chem (2010) 1.36

Differential expression of CD146 in tissues and endothelial cells derived from infantile haemangioma and normal human skin. J Pathol (2003) 1.35

Genome scans provide evidence for keloid susceptibility loci on chromosomes 2q23 and 7p11. J Invest Dermatol (2004) 1.34

Analysis of CD44-hyaluronan interactions in an artificial membrane system: insights into the distinct binding properties of high and low molecular weight hyaluronan. J Biol Chem (2010) 1.34

Collagen XVIII/endostatin is essential for vision and retinal pigment epithelial function. EMBO J (2003) 1.34

Disrupted function of tumor necrosis factor-alpha-stimulated gene 6 blocks cumulus cell-oocyte complex expansion. Endocrinology (2003) 1.34

Structural characterization of PTX3 disulfide bond network and its multimeric status in cumulus matrix organization. J Biol Chem (2008) 1.33

Loss of collagen XVIII enhances neovascularization and vascular permeability in atherosclerosis. Circulation (2004) 1.30

Shiga toxin activates complement and binds factor H: evidence for an active role of complement in hemolytic uremic syndrome. J Immunol (2009) 1.29

Molecular interplay between endostatin, integrins, and heparan sulfate. J Biol Chem (2009) 1.25

The inflammation-associated protein TSG-6 cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers. J Biol Chem (2011) 1.23

Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4. Dev Biol (2003) 1.23

Point-of-care ultrasound in intensive care units: assessment of 1073 procedures in a multicentric, prospective, observational study. Intensive Care Med (2015) 1.22

TSG-6 potentiates the antitissue kallikrein activity of inter-alpha-inhibitor through bikunin release. Am J Respir Cell Mol Biol (2006) 1.21

Endothelin-converting enzyme 1 degrades neuropeptides in endosomes to control receptor recycling. Proc Natl Acad Sci U S A (2007) 1.21

Modulation of macrophage activation state protects tissue from necrosis during critical limb ischemia in thrombospondin-1-deficient mice. PLoS One (2008) 1.21

The exchangeable apolipoprotein ApoC-I promotes membrane fusion of hepatitis C virus. J Biol Chem (2007) 1.21

Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation. Mol Immunol (2008) 1.21

Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestins. J Cell Biol (2007) 1.20

Hyaluronan fragments/CD44 mediate oxidative stress-induced MUC5B up-regulation in airway epithelium. Am J Respir Cell Mol Biol (2008) 1.18

Targeted disruption of Col8a1 and Col8a2 genes in mice leads to anterior segment abnormalities in the eye. FASEB J (2005) 1.18

Characterization of the interaction between tumor necrosis factor-stimulated gene-6 and heparin: implications for the inhibition of plasmin in extracellular matrix microenvironments. J Biol Chem (2005) 1.16

Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane. Blood (2011) 1.16

Kinesin-2 controls development and patterning of the vertebrate skeleton by Hedgehog- and Gli3-dependent mechanisms. Dev Biol (2007) 1.15

Specificity of the tumor necrosis factor-induced protein 6-mediated heavy chain transfer from inter-alpha-trypsin inhibitor to hyaluronan: implications for the assembly of the cumulus extracellular matrix. J Biol Chem (2004) 1.15

Interaction of the coiled-coil domain with glycosaminoglycans protects angiopoietin-like 4 from proteolysis and regulates its antiangiogenic activity. FASEB J (2008) 1.13

A novel allelic variant of the human TSG-6 gene encoding an amino acid difference in the CUB module. Chromosomal localization, frequency analysis, modeling, and expression. J Biol Chem (2002) 1.13

The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2. J Biol Chem (2010) 1.13

Overexpression of hyaluronan synthase 2 alters hyaluronan distribution and function in proximal tubular epithelial cells. J Am Soc Nephrol (2006) 1.11

Evaluation of antimicrobial therapy management of 120 consecutive patients with secondary peritonitis. J Antimicrob Chemother (2002) 1.11

TSG-6 binds via its CUB_C domain to the cell-binding domain of fibronectin and increases fibronectin matrix assembly. Matrix Biol (2007) 1.11

Identification of an antiangiogenic FGF2-binding site in the N terminus of the soluble pattern recognition receptor PTX3. J Biol Chem (2006) 1.10

Use of 15N-NMR to resolve molecular details in isotopically-enriched carbohydrates: sequence-specific observations in hyaluronan oligomers up to decasaccharides. Glycobiology (2004) 1.09

Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. A prospective, multiple-center study. Crit Care (2011) 1.08

Characterization of endostatin binding to heparin and heparan sulfate by surface plasmon resonance and molecular modeling: role of divalent cations. J Biol Chem (2003) 1.07

Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions. J Immunol (2013) 1.06

Substrate affinity and substrate specificity of proteasomes with RNase activity. Mol Biol Rep (2003) 1.06

Growth of cranial synchondroses and sutures requires polycystin-1. Dev Biol (2008) 1.06