Published in J Virol on November 01, 1999
Strategy for nonenveloped virus entry: a hydrophobic conformer of the reovirus membrane penetration protein micro 1 mediates membrane disruption. J Virol (2002) 2.02
Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors. J Virol (2006) 1.49
Beta1 integrin mediates internalization of mammalian reovirus. J Virol (2006) 1.43
Virion disassembly is required for apoptosis induced by reovirus. J Virol (2002) 1.40
Reovirus sigma NS and mu NS proteins form cytoplasmic inclusion structures in the absence of viral infection. J Virol (2003) 1.23
Sites and determinants of early cleavages in the proteolytic processing pathway of reovirus surface protein sigma3. J Virol (2002) 1.17
Complete in vitro assembly of the reovirus outer capsid produces highly infectious particles suitable for genetic studies of the receptor-binding protein. J Virol (2001) 1.17
Addition of exogenous protease facilitates reovirus infection in many restrictive cells. J Virol (2002) 1.13
Gene-specific inhibition of reovirus replication by RNA interference. J Virol (2006) 1.12
Identification of functional domains in reovirus replication proteins muNS and mu2. J Virol (2009) 1.10
Neutrophil elastase, an acid-independent serine protease, facilitates reovirus uncoating and infection in U937 promonocyte cells. Virol J (2005) 1.05
Reovirus forms neo-organelles for progeny particle assembly within reorganized cell membranes. MBio (2014) 1.04
Transport to late endosomes is required for efficient reovirus infection. J Virol (2012) 1.03
From touchdown to transcription: the reovirus cell entry pathway. Curr Top Microbiol Immunol (2010) 1.01
JAM-A-independent, antibody-mediated uptake of reovirus into cells leads to apoptosis. J Virol (2006) 1.00
Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3. J Virol (2001) 0.94
The oncolytic effect in vivo of reovirus on tumour cells that have survived reovirus cell killing in vitro. Br J Cancer (2006) 0.90
Impact of host proteases on reovirus infection in the respiratory tract. J Virol (2011) 0.89
Reovirus variants selected for resistance to ammonium chloride have mutations in viral outer-capsid protein sigma3. J Virol (2006) 0.89
Src kinase mediates productive endocytic sorting of reovirus during cell entry. J Virol (2011) 0.87
Molecular determinants of proteolytic disassembly of the reovirus outer capsid. J Biol Chem (2012) 0.85
Reovirus variants with mutations in genome segments S1 and L2 exhibit enhanced virion infectivity and superior oncolysis. J Virol (2012) 0.84
The crucial role of bile acids in the entry of porcine enteric calicivirus. Virology (2014) 0.83
The μ1 72-96 loop controls conformational transitions during reovirus cell entry. J Virol (2013) 0.81
Reovirus replication protein μ2 influences cell tropism by promoting particle assembly within viral inclusions. J Virol (2012) 0.80
Proteolytic disassembly of viral outer capsid proteins is crucial for reovirus-mediated type-I interferon induction in both reovirus-susceptible and reovirus-refractory tumor cells. Biomed Res Int (2015) 0.79
Activity levels of cathepsins B and L in tumor cells are a biomarker for efficacy of reovirus-mediated tumor cell killing. Cancer Gene Ther (2015) 0.79
Proteasome inhibitors enhance bacteriophage lambda (lambda) mediated gene transfer in mammalian cells. Virology (2008) 0.77
Conformational changes required for reovirus cell entry are sensitive to pH. Virology (2015) 0.75
Novel High-throughput Approach for Purification of Infectious Virions. Sci Rep (2016) 0.75
The biogenesis of lysosomes. Annu Rev Cell Biol (1989) 10.73
Rapid acidification of endocytic vesicles containing alpha 2-macroglobulin. Cell (1982) 7.23
Cathepsin B, Cathepsin H, and cathepsin L. Methods Enzymol (1981) 6.84
L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L. Biochem J (1982) 5.67
Sigma 1 protein of mammalian reoviruses extends from the surfaces of viral particles. J Virol (1988) 4.77
Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing). J Virol (1988) 3.84
Intracellular digestion of reovirus particles requires a low pH and is an essential step in the viral infectious cycle. J Virol (1987) 3.65
Intracellular proteases. Annu Rev Biochem (1987) 2.96
Cathepsin L. A new proteinase from rat-liver lysosomes. Eur J Biochem (1977) 2.75
Trafficking of lysosomal enzymes. FASEB J (1987) 2.71
The mechanisms of reovirus uncoating and gene activation in vivo. Virology (1972) 2.60
Fate of parental reovirus in infected cell. Virology (1971) 2.49
Proteolytic digestion of reovirus in the intestinal lumens of neonatal mice. J Virol (1989) 2.38
Role of the host cell in persistent viral infection: coevolution of L cells and reovoirus during persistent infection. Cell (1981) 2.23
Reovirus: evidence for a second step in the intracellular uncoating and transcriptase activation process. Virology (1981) 2.20
Cloning and characterization of a mouse cysteine proteinase. J Biol Chem (1986) 2.12
Two modes of entry of reovirus particles into L cells. J Gen Virol (1979) 2.04
Reovirus M2 gene is associated with chromium release from mouse L cells. J Virol (1993) 1.99
Distinct binding sites for zinc and double-stranded RNA in the reovirus outer capsid protein sigma 3. Mol Cell Biol (1988) 1.96
The reovirus replicative cycle: conservation of parental RNA and protein. Proc Natl Acad Sci U S A (1970) 1.76
Infectious subvirion particles of reovirus type 3 Dearing exhibit a loss in infectivity and contain a cleaved sigma 1 protein. J Virol (1995) 1.68
Mutations in reovirus outer-capsid protein sigma3 selected during persistent infections of L cells confer resistance to protease inhibitor E64. J Virol (1997) 1.66
Ion channels induced in lipid bilayers by subvirion particles of the nonenveloped mammalian reoviruses. Proc Natl Acad Sci U S A (1993) 1.64
Lysosomes. Essays Biochem (1976) 1.58
Role of the mu 1 protein in reovirus stability and capacity to cause chromium release from host cells. J Virol (1996) 1.58
Intraluminal proteolytic activation plays an important role in replication of type 1 reovirus in the intestines of neonatal mice. J Virol (1990) 1.56
The major excreted protein (MEP) of transformed mouse cells and cathepsin L have similar protease specificity. Biochem Biophys Res Commun (1986) 1.50
Tumor promoters and Kirsten sarcoma virus increase synthesis of a secreted glycoprotein by regulating levels of translatable mRNA. Cell (1980) 1.50
Cells and viruses with mutations affecting viral entry are selected during persistent infections of L cells with mammalian reoviruses. J Virol (1993) 1.48
Rat procathepsin B. Proteolytic processing to the mature form in vitro. J Biol Chem (1992) 1.44
Processing and lysosomal localization of a glycoprotein whose secretion is transformation stimulated. J Cell Biol (1985) 1.41
Role of the S4 gene in the establishment of persistent reovirus infection in L cells. Cell (1982) 1.38
Persistent infections in L cells with temperature-sensitive mutants of reovirus. J Virol (1977) 1.37
Reovirus variants selected during persistent infections of L cells contain mutations in the viral S1 and S4 genes and are altered in viral disassembly. J Virol (1997) 1.27
Protease cleavage of reovirus capsid protein mu1/mu1C is blocked by alkyl sulfate detergents, yielding a new type of infectious subvirion particle. J Virol (1998) 1.27
Potency and selectivity of the cathepsin L propeptide as an inhibitor of cysteine proteases. Biochemistry (1996) 1.26
The entry of reovirus into L cells is dependent on vacuolar proton-ATPase activity. J Virol (1996) 1.24
Cleavage susceptibility of reovirus attachment protein sigma1 during proteolytic disassembly of virions is determined by a sequence polymorphism in the sigma1 neck. J Virol (1998) 1.22
Reovirus type 3 genome segment S4: nucleotide sequence of the gene encoding a major virion surface protein. J Virol (1984) 1.17
Efficiency of viral entry determines the capacity of murine erythroleukemia cells to support persistent infections by mammalian reoviruses. J Virol (1997) 1.16
The proregion of cathepsin L is required for proper folding, stability, and ER exit. Arch Biochem Biophys (1994) 1.10
Monoclonal antibodies to reovirus sigma 1 and mu 1 proteins inhibit chromium release from mouse L cells. J Virol (1996) 1.09
Receptor utilization by reovirus type 3: distinct binding sites on thymoma and fibroblast cell lines result in differential compartmentalization of virions. Microb Pathog (1992) 1.07
No role for pepstatin-A-sensitive acidic proteinases in reovirus infections of L or MDCK cells. Virology (1998) 1.04
Procathepsins L and D are membrane-bound in acidic microsomal vesicles. J Biol Chem (1991) 1.03
Association of reovirus outer capsid proteins sigma 3 and mu 1 causes a conformational change that renders sigma 3 protease sensitive. J Virol (1995) 1.00
Activity of the multidrug transporter results in alkalinization of the cytosol: measurement of cytosolic pH by microinjection of a pH-sensitive dye. J Histochem Cytochem (1990) 1.00
The penetration of reovirus RNA and initiation of its genetic function in L-strain fibroblasts. J Cell Biol (1968) 1.00
The lysosomal proenzyme receptor that binds procathepsin L to microsomal membranes at pH 5 is a 43-kDa integral membrane protein. Proc Natl Acad Sci U S A (1993) 0.97
Interaction of lysosomal cysteine proteinases with alpha 2-macroglobulin: conclusive evidence for the endopeptidase activities of cathepsins B and H. Arch Biochem Biophys (1989) 0.96
Inhibitor studies indicate that active cathepsin L is probably essential to its own processing in cultured fibroblasts. Biochem J (1990) 0.95
Genetic variation during persistent reovirus infection: isolation of cold-sensitive and temperature-sensitive mutants from persistently infected L cells. Virology (1983) 0.88
Molecular mechanisms of persistent infection by reovirus. Curr Top Microbiol Immunol (1998) 0.84
Abnormal glycosylation of procathepsin L due to N-terminal point mutations correlates with failure to sort to lysosomes. J Biol Chem (1997) 0.83
Microglial cathepsin B: an immunological examination of cellular and secreted species. J Neurochem (1995) 0.80
Translocation of proteins across membranes: the signal hypothesis and beyond. Symp Soc Exp Biol (1979) 4.54
Cell-free translation of messenger RNA in a wheat germ system. Methods Enzymol (1983) 4.52
Junction adhesion molecule is a receptor for reovirus. Cell (2001) 4.00
Biosynthesis of a lysosomal enzyme. Partial structure of two transient and functionally distinct NH2-terminal sequences in cathepsin D. J Biol Chem (1981) 2.47
Early events in the biosynthesis of the lysosomal enzyme cathepsin D. J Biol Chem (1979) 2.43
Differences in the capacity of reovirus strains to induce apoptosis are determined by the viral attachment protein sigma 1. J Virol (1995) 2.14
Cloning and characterization of a mouse cysteine proteinase. J Biol Chem (1986) 2.12
Utilization of sialic acid as a coreceptor enhances reovirus attachment by multistep adhesion strengthening. J Biol Chem (2000) 2.12
Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis. J Virol (1997) 1.90
Reovirus-induced apoptosis of MDCK cells is not linked to viral yield and is blocked by Bcl-2. J Virol (1997) 1.84
Structure of the reovirus cell-attachment protein: a model for the domain organization of sigma 1. J Virol (1990) 1.71
Infectious subvirion particles of reovirus type 3 Dearing exhibit a loss in infectivity and contain a cleaved sigma 1 protein. J Virol (1995) 1.68
Reovirus-induced apoptosis requires activation of transcription factor NF-kappaB. J Virol (2000) 1.68
Mutations in reovirus outer-capsid protein sigma3 selected during persistent infections of L cells confer resistance to protease inhibitor E64. J Virol (1997) 1.66
Identification of carbohydrate-binding domains in the attachment proteins of type 1 and type 3 reoviruses. J Virol (2000) 1.64
Mutations in type 3 reovirus that determine binding to sialic acid are contained in the fibrous tail domain of viral attachment protein sigma1. J Virol (1997) 1.50
Biosynthesis of the lysosomal enzyme glucocerebrosidase. J Biol Chem (1985) 1.48
Coexisting hyperplastic antral polyp and hypertrophic pyloric stenosis. Pediatr Radiol (1997) 1.47
Carboxyl-terminal proteolytic processing during biosynthesis of the lysosomal enzymes beta-glucuronidase and cathepsin D. Biochemistry (1983) 1.46
Linkage between reovirus-induced apoptosis and inhibition of cellular DNA synthesis: role of the S1 and M2 genes. J Virol (1996) 1.46
Reovirus binding to cell surface sialic acid potentiates virus-induced apoptosis. J Virol (2001) 1.43
Reovirus-induced G(2)/M cell cycle arrest requires sigma1s and occurs in the absence of apoptosis. J Virol (2000) 1.31
Reovirus-induced apoptosis is preceded by increased cellular calpain activity and is blocked by calpain inhibitors. J Virol (1999) 1.30
Reovirus sigmaNS protein is required for nucleation of viral assembly complexes and formation of viral inclusions. J Virol (2001) 1.29
Reovirus variants selected during persistent infections of L cells contain mutations in the viral S1 and S4 genes and are altered in viral disassembly. J Virol (1997) 1.27
Cleavage susceptibility of reovirus attachment protein sigma1 during proteolytic disassembly of virions is determined by a sequence polymorphism in the sigma1 neck. J Virol (1998) 1.22
Reovirus growth in cell culture does not require the full complement of viral proteins: identification of a sigma1s-null mutant. J Virol (1998) 1.17
Complete in vitro assembly of the reovirus outer capsid produces highly infectious particles suitable for genetic studies of the receptor-binding protein. J Virol (2001) 1.17
Efficiency of viral entry determines the capacity of murine erythroleukemia cells to support persistent infections by mammalian reoviruses. J Virol (1997) 1.16
Reovirus-induced sigma1s-dependent G(2)/M phase cell cycle arrest is associated with inhibition of p34(cdc2). J Virol (2001) 1.16
Reovirus mu2 protein determines strain-specific differences in the rate of viral inclusion formation in L929 cells. Virology (2000) 1.12
Binding of type 3 reovirus by a domain of the sigma 1 protein important for hemagglutination leads to infection of murine erythroleukemia cells. J Clin Invest (1992) 1.12
Sequence diversity within the reovirus S3 gene: reoviruses evolve independently of host species, geographic locale, and date of isolation. Virology (1996) 1.10
Herpes simplex virus type 1 latency in the murine nervous system is associated with oxidative damage to neurons. Virology (2000) 1.09
Using CT of the cervical spine for early evaluation of pediatric patients with head trauma. AJR Am J Roentgenol (2001) 1.08
Role of oxidative damage in the pathogenesis of viral infections of the nervous system. Histol Histopathol (2005) 1.06
Canines as sentinel species for assessing chronic exposures to air pollutants: part 1. Respiratory pathology. Toxicol Sci (2001) 1.06
Sequence diversity within the reovirus S2 gene: reovirus genes reassort in nature, and their termini are predicted to form a panhandle motif. J Virol (1994) 1.06
Mechanisms of bacterial resistance to antibiotics. Arch Intern Med (1991) 1.06
Procathepsins L and D are membrane-bound in acidic microsomal vesicles. J Biol Chem (1991) 1.03
Attachment and cell entry of mammalian orthoreovirus. Curr Top Microbiol Immunol (2006) 1.02
Apoptosis and the cytopathic effects of reovirus. Curr Top Microbiol Immunol (1998) 1.00
The pH-dependent membrane association of procathepsin L is mediated by a 9-residue sequence within the propeptide. J Biol Chem (1994) 1.00
Group A streptococcal necrotizing fasciitis following varicella in children: case reports and review. Clin Infect Dis (1995) 1.00
Imaging of congenital vascular and lymphatic anomalies of the head and neck. Neuroimaging Clin N Am (2000) 0.99
Persistent reovirus infections of L cells select mutations in viral attachment protein sigma1 that alter oligomer stability. J Virol (1996) 0.99
The lysosomal proenzyme receptor that binds procathepsin L to microsomal membranes at pH 5 is a 43-kDa integral membrane protein. Proc Natl Acad Sci U S A (1993) 0.97
A monoclonal antibody specific for reovirus outer-capsid protein sigma3 inhibits sigma1-mediated hemagglutination by steric hindrance. J Virol (2001) 0.95
Reovirus receptors and apoptosis. Virology (2001) 0.95
Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3. J Virol (2001) 0.94
Biosynthesis and intracellular targeting of the lysosomal aspartic proteinase cathepsin D. Adv Exp Med Biol (1998) 0.94
Comparative amino acid analysis of influenza A viral proteins. Virology (1980) 0.94
Hepatocyte nuclear factor-1 acts as an accessory factor to enhance the inhibitory action of insulin on mouse glucose-6-phosphatase gene transcription. Proc Natl Acad Sci U S A (1998) 0.93
Unilateral renal cystic disease in an adult. Abdom Imaging (1994) 0.92
Viruses and cells with mutations affecting viral entry are selected during persistent rotavirus infections of MA104 cells. J Virol (1998) 0.91
Translocation of a lysosomal enzyme across the microsomal membrane requires signal recognition particle. Biochem Biophys Res Commun (1983) 0.90
Endocarditis caused by group A beta-hemolytic Streptococcus in an infant: case report and review. Clin Infect Dis (1999) 0.88
Prolonged replication in the mouse central nervous system of reoviruses isolated from persistently infected cell cultures. J Virol (1993) 0.87
Effects of occlusal stimuli on alveolar/jaw bone formation. J Dent Res (2007) 0.86
Mutation in the hemagglutinin of A/N-WS/33 influenza virus recombinants influencing sensitivity to trypsin and antigenic reactivity. Virology (1980) 0.86
Ehrlichiosis: findings on chest radiographs in three pediatric patients. AJR Am J Roentgenol (1998) 0.84
Meningitis caused by mixed anaerobic species complicating tethered cord syndrome. Clin Infect Dis (1995) 0.84
Abnormal glycosylation of procathepsin L due to N-terminal point mutations correlates with failure to sort to lysosomes. J Biol Chem (1997) 0.83
Mutations selected in rotavirus enterotoxin NSP4 depend on the context of its expression. Virology (2000) 0.83
Cellular and humoral immunity to reovirus infection. Curr Top Microbiol Immunol (1998) 0.82
Isolated lymphoma of genitourinary tract and adrenals. Urology (1993) 0.81
Exposure to air pollution is associated with lung hyperinflation in healthy children and adolescents in Southwest Mexico City: a pilot study. Inhal Toxicol (2000) 0.80
Assessment of masticatory function in patients with non-sagittal occlusal discrepancies. J Oral Rehabil (2014) 0.78
Test of the contribution of an amino-aromatic hydrogen bond to protein function. Biochemistry (1995) 0.78
Imaging of congenital anomalies of the branchial apparatus. Neuroimaging Clin N Am (2000) 0.78
Magnetic resonance imaging of neuroblastoma using current techniques. Magn Reson Imaging (1999) 0.78
Histomorphometric evaluation of maxillary molar roots and surrounding periodontium following molar intrusion in rats. Orthod Craniofac Res (2014) 0.78
Influenzal pneumonia as a complication of autologous bone marrow transplantation. Clin Infect Dis (1992) 0.77
Hemorrhagic myelolipoma of adrenal gland after blunt trauma. Urology (1991) 0.76
The reovirus S4 gene 3' nontranslated region contains a translational operator sequence. J Virol (2001) 0.76
Brain- and intestine-specific variants of reovirus serotype 3 strain dearing are selected during chronic infection of severe combined immunodeficient mice. J Virol (1995) 0.76
Procathepsin L self-association as a mechanism for selective secretion. Traffic (2000) 0.76
Spectral entropy monitoring allowed lower sevoflurane concentration and faster recovery in children. Acta Anaesthesiol Scand (2010) 0.76
Fever and encephalopathy in two school age boys. Pediatr Infect Dis J (1998) 0.75
Divergence of brain prostaglandin H synthase activity and oxidative damage in mice with encephalitis. J Neuropathol Exp Neurol (1999) 0.75
Visualization of protein losing enteropathy in infantile systemic hyalinosis with Tc-99m HSA after albumin challenge. Clin Nucl Med (1996) 0.75
Metabolic consequences of genetic defects in lysosomes. Biochem Soc Trans (1984) 0.75
Pseudobullseye sign of the testicle. A window to the peritoneum. Clin Nucl Med (1991) 0.75
Enterococcal meningitis in an infant complicating congenital cutis aplasia. Pediatr Infect Dis J (2000) 0.75
An innovative AIDS elective. Acad Med (1997) 0.75
Protection of phagocytic macrophages from peroxidative damage by selenium and vitamin E. Yonsei Med J (1982) 0.75