Published in Proc Natl Acad Sci U S A on November 15, 1993
Structure of the reovirus membrane-penetration protein, Mu1, in a complex with is protector protein, Sigma3. Cell (2002) 2.24
A membrane-destabilizing peptide in capsid protein L2 is required for egress of papillomavirus genomes from endosomes. J Virol (2006) 2.16
Differences in the capacity of reovirus strains to induce apoptosis are determined by the viral attachment protein sigma 1. J Virol (1995) 2.14
Strategy for nonenveloped virus entry: a hydrophobic conformer of the reovirus membrane penetration protein micro 1 mediates membrane disruption. J Virol (2002) 2.02
In vitro recoating of reovirus cores with baculovirus-expressed outer-capsid proteins mu1 and sigma3. J Virol (1999) 1.67
Characterization of the ion channels formed by poliovirus in planar lipid membranes. J Virol (1997) 1.67
Role of the mu 1 protein in reovirus stability and capacity to cause chromium release from host cells. J Virol (1996) 1.58
The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry. J Virol (2003) 1.56
Virus-mediated release of endosomal content in vitro: different behavior of adenovirus and rhinovirus serotype 2. J Cell Biol (1995) 1.55
Linkage between reovirus-induced apoptosis and inhibition of cellular DNA synthesis: role of the S1 and M2 genes. J Virol (1996) 1.46
Mammalian reovirus, a nonfusogenic nonenveloped virus, forms size-selective pores in a model membrane. Proc Natl Acad Sci U S A (2006) 1.44
Selective membrane permeabilization by the rotavirus VP5* protein is abrogated by mutations in an internal hydrophobic domain. J Virol (2000) 1.40
Protease cleavage of reovirus capsid protein mu1/mu1C is blocked by alkyl sulfate detergents, yielding a new type of infectious subvirion particle. J Virol (1998) 1.27
Proteolytic processing of reovirus is required for adherence to intestinal M cells. J Virol (1994) 1.26
Structure of the reovirus outer capsid and dsRNA-binding protein sigma3 at 1.8 A resolution. EMBO J (2001) 1.25
Mutant cells selected during persistent reovirus infection do not express mature cathepsin L and do not support reovirus disassembly. J Virol (1999) 1.24
Reovirus apoptosis and virulence are regulated by host cell membrane penetration efficiency. J Virol (2007) 1.24
The entry of reovirus into L cells is dependent on vacuolar proton-ATPase activity. J Virol (1996) 1.24
Reovirus sigma NS and mu NS proteins form cytoplasmic inclusion structures in the absence of viral infection. J Virol (2003) 1.23
Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells. J Virol (2005) 1.23
Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domain. PLoS Pathog (2008) 1.19
Sites and determinants of early cleavages in the proteolytic processing pathway of reovirus surface protein sigma3. J Virol (2002) 1.17
Protective antibodies inhibit reovirus internalization and uncoating by intracellular proteases. J Virol (1994) 1.17
Role of recycling endosomes and lysosomes in dynein-dependent entry of canine parvovirus. J Virol (2002) 1.14
Addition of exogenous protease facilitates reovirus infection in many restrictive cells. J Virol (2002) 1.13
Monoclonal antibodies to reovirus sigma 1 and mu 1 proteins inhibit chromium release from mouse L cells. J Virol (1996) 1.09
From touchdown to transcription: the reovirus cell entry pathway. Curr Top Microbiol Immunol (2010) 1.01
JAM-A-independent, antibody-mediated uptake of reovirus into cells leads to apoptosis. J Virol (2006) 1.00
Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3. J Virol (2001) 0.94
Effect of mutations in VP5 hydrophobic loops on rotavirus cell entry. J Virol (2010) 0.94
Morphological changes in the T=3 capsid of Flock House virus during cell entry. J Virol (2006) 0.90
Avian reovirus major mu-class outer capsid protein influences efficiency of productive macrophage infection in a virus strain-specific manner. J Virol (2001) 0.85
Reovirus receptors, cell entry, and proapoptotic signaling. Adv Exp Med Biol (2013) 0.84
Interference following mixed infection of reovirus isolates is linked to the M2 gene. J Virol (1994) 0.79
Viral and cellular membrane fusion proteins. Annu Rev Physiol (1990) 6.13
Protein-mediated membrane fusion. Annu Rev Biophys Biophys Chem (1989) 3.99
Intracellular digestion of reovirus particles requires a low pH and is an essential step in the viral infectious cycle. J Virol (1987) 3.65
Protein sigma 1 is the reovirus cell attachment protein. Virology (1981) 3.48
Patch clamp studies of single cell-fusion events mediated by a viral fusion protein. Nature (1989) 2.83
Proteolytic digestion of reovirus in the intestinal lumens of neonatal mice. J Virol (1989) 2.38
Activation and characterization of the reovirus transcriptase: genetic analysis. J Virol (1982) 2.36
Mammalian reoviruses contain a myristoylated structural protein. J Virol (1991) 2.09
Interaction of reovirus with cell surface receptors. I. Murine and human lymphocytes have a receptor for the hemagglutinin of reovirus type 3. J Immunol (1980) 2.06
Reovirus M2 gene is associated with chromium release from mouse L cells. J Virol (1993) 1.99
The first milliseconds of the pore formed by a fusogenic viral envelope protein during membrane fusion. Proc Natl Acad Sci U S A (1991) 1.94
Mechanisms of viral pathogenesis. Distinct forms of reoviruses and their roles during replication in cells and host. J Clin Invest (1991) 1.73
Kinetics and stability of alamethicin conducting channels in lipid bilayers. Biochim Biophys Acta (1976) 1.26
Voltage-dependent channel formation by rods of helical polypeptides. J Membr Biol (1986) 1.23
Voltage-gated channels formed in lipid bilayers by a positively charged segment of the Na-channel polypeptide. Proc Natl Acad Sci U S A (1989) 1.16
Peptides as promoters of ion-permeable channels. Regul Pept Suppl (1985) 1.05
The synthetic precursor specific region of pre-pro-parathyroid hormone forms ion channels in lipid bilayers. Biosci Rep (1988) 1.03
Sigma 1 protein of mammalian reoviruses extends from the surfaces of viral particles. J Virol (1988) 4.77
Structure of the reovirus core at 3.6 A resolution. Nature (2000) 4.28
Molecular basis of reovirus virulence: role of the S1 gene. Proc Natl Acad Sci U S A (1977) 3.97
Genome RNAs and polypeptides of reovirus serotypes 1, 2, and 3. J Virol (1977) 3.87
Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing). J Virol (1988) 3.84
Isolation and preliminary genetic and biochemical characterization of temperature-sensitive mutants of reovirus. Virology (1969) 3.66
Intracellular digestion of reovirus particles requires a low pH and is an essential step in the viral infectious cycle. J Virol (1987) 3.65
Absolute linkage of virulence and central nervous system cell tropism of reoviruses to viral hemagglutinin. J Infect Dis (1980) 3.27
Intestinal M cells: a pathway for entry of reovirus into the host. Science (1981) 3.23
Distinct pathways of viral spread in the host determined by reovirus S1 gene segment. Science (1986) 2.61
Evidence for functional domains on the reovirus type 3 hemagglutinin. Virology (1982) 2.55
Neutralization of reovirus: the gene responsible for the neutralization antigen. J Exp Med (1977) 2.53
Genetics of reovirus: identification of the ds RNA segments encoding the polypeptides of the mu and sigma size classes. Virology (1978) 2.51
Host restriction of Friend leukemia virus. Role of the viral outer coat. Proc Natl Acad Sci U S A (1973) 2.44
Proteolytic digestion of reovirus in the intestinal lumens of neonatal mice. J Virol (1989) 2.38
Monoclonal antibodies to reovirus reveal structure/function relationships between capsid proteins and genetics of susceptibility to antibody action. J Virol (1991) 2.37
Activation and characterization of the reovirus transcriptase: genetic analysis. J Virol (1982) 2.36
Molecular basis of reovirus virulence. Role of the M2 gene. J Exp Med (1980) 2.32
A carboxy-terminal fragment of protein mu 1/mu 1C is present in infectious subvirion particles of mammalian reoviruses and is proposed to have a role in penetration. J Virol (1992) 2.29
Identification of the gene coding for the hemagglutinin of reovirus. Virology (1978) 2.28
Role of the host cell in persistent viral infection: coevolution of L cells and reovoirus during persistent infection. Cell (1981) 2.23
Intracellular synthesis of measles virus-specified polypeptides. J Virol (1978) 2.21
Polymorphism of the migration of double-stranded RNA genome segments of reovirus isolates from humans, cattle, and mice. J Virol (1979) 2.15
Identification of attenuating mutations on the reovirus type 3 S1 double-stranded RNA segment with a rapid sequencing technique. J Virol (1986) 2.15
Characterization of a zinc blotting technique: evidence that a retroviral gag protein binds zinc. Proc Natl Acad Sci U S A (1988) 2.13
Attenuated reovirus type 3 strains generated by selection of haemagglutinin antigenic variants. Nature (1982) 2.11
Mammalian reoviruses contain a myristoylated structural protein. J Virol (1991) 2.09
Reovirus inhibition of cellular RNA and protein synthesis: role of the S4 gene. Virology (1982) 2.08
Interaction of reovirus with cell surface receptors. I. Murine and human lymphocytes have a receptor for the hemagglutinin of reovirus type 3. J Immunol (1980) 2.06
Reovirus M2 gene is associated with chromium release from mouse L cells. J Virol (1993) 1.99
Distinct binding sites for zinc and double-stranded RNA in the reovirus outer capsid protein sigma 3. Mol Cell Biol (1988) 1.96
Determinants of reovirus interaction with the intestinal M cells and absorptive cells of murine intestine. Gastroenterology (1983) 1.95
Sequence of reovirus haemagglutinin predicts a coiled-coil structure. Nature (1985) 1.95
The so-called "Paracolon" bacteria. A bacteriologic and clinical reappraisal. Am J Med (1967) 1.88
A genetic map of reovirus. II. Assignment of the double-stranded RNA-negative mutant groups C, D, and E to genome segments. Virology (1978) 1.87
Genetic studies on the mechanism of chemical and physical inactivation of reovirus. J Gen Virol (1982) 1.84
Hemagglutinin variants of reovirus type 3 have altered central nervous system tropism. Science (1983) 1.82
Binding and transepithelial transport of immunoglobulins by intestinal M cells: demonstration using monoclonal IgA antibodies against enteric viral proteins. J Cell Biol (1989) 1.82
Temperature-sensitive mutants of reovirus type 3: studies on the synthesis of viral RNA. Virology (1972) 1.77
Genetic and molecular mechanisms of viral pathogenesis: implications for prevention and treatment. Nature (1982) 1.75
Hemagglutinin of rabies and some other bullet-shaped viruses. Proc Soc Exp Biol Med (1968) 1.74
Mechanisms of viral pathogenesis. Distinct forms of reoviruses and their roles during replication in cells and host. J Clin Invest (1991) 1.73
A genetic map of reovirus. 1. Correlation of genome RNAs between serotypes 1, 2, and 3. Virology (1978) 1.72
Structure of the reovirus cell-attachment protein: a model for the domain organization of sigma 1. J Virol (1990) 1.71
Molecular basis of reovirus neurovirulence: role of the M2 gene in avirulence. Proc Natl Acad Sci U S A (1982) 1.71
Isolation and biochemical characterization of the mammalian reovirus type 3 cell-surface receptor. Proc Natl Acad Sci U S A (1985) 1.70
Molecular structure of the cell-attachment protein of reovirus: correlation of computer-processed electron micrographs with sequence-based predictions. J Virol (1990) 1.69
In vitro recoating of reovirus cores with baculovirus-expressed outer-capsid proteins mu1 and sigma3. J Virol (1999) 1.67
Identification of a hemagglutinin-specific idiotype associated with reovirus recognition shared by lymphoid and neural cells. J Exp Med (1982) 1.64
Growth and survival of reovirus in intestinal tissue: role of the L2 and S1 genes. J Virol (1989) 1.64
The sigma 1 protein determines the extent of spread of reovirus from the gastrointestinal tract of mice. Virology (1983) 1.63
Direct spread of reovirus from the intestinal lumen to the central nervous system through vagal autonomic nerve fibers. Proc Natl Acad Sci U S A (1991) 1.60
Role of the mu 1 protein in reovirus stability and capacity to cause chromium release from host cells. J Virol (1996) 1.58
A sigma 1 region important for hemagglutination by serotype 3 reovirus strains. J Virol (1990) 1.57
Identification of a new polypeptide coded by reovirus gene S1. J Virol (1985) 1.57
Why the smallpox virus stocks should not be destroyed. Science (1993) 1.56
Intraluminal proteolytic activation plays an important role in replication of type 1 reovirus in the intestines of neonatal mice. J Virol (1990) 1.56
Protective anti-reovirus monoclonal antibodies and their effects on viral pathogenesis. J Virol (1993) 1.55
The interaction of mammalian reoviruses with the cytoskeleton of monkey kidney CV-1 cells. Virology (1982) 1.55
Temperature-sensitive mutants of reovirus type 3 features of genetic recombination. Virology (1971) 1.53
Genetic manipulation of reovirus--a model for modification of disease. N Engl J Med (1972) 1.53
The reovirus M1 gene, encoding a viral core protein, is associated with the myocarditic phenotype of a reovirus variant. J Virol (1989) 1.52
Immune response in subacute sclerosing panencephalitis: reduced antibody response to the matrix protein of measles virus. J Immunol (1979) 1.52
Rotavirus open cores catalyze 5'-capping and methylation of exogenous RNA: evidence that VP3 is a methyltransferase. Virology (1999) 1.51
Crystallization of the reovirus type 3 Dearing core. Crystal packing is determined by the lambda 2 protein. J Mol Biol (1990) 1.51
Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells. Science (1983) 1.50
Temperature-sensitive mutants of reovirus type 3: defects in viral maturation as studied by immunofluorescence and electron microscopy. Virology (1971) 1.50
Generation of cytolytic T lymphocytes after reovirus infection: role of S1 gene. Proc Natl Acad Sci U S A (1979) 1.50
Derivation and characterization of an efficiently myocarditic reovirus variant. J Virol (1989) 1.49
Cells and viruses with mutations affecting viral entry are selected during persistent infections of L cells with mammalian reoviruses. J Virol (1993) 1.48
Syngeneic monoclonal antiidiotype can induce cellular immunity to reovirus. J Exp Med (1984) 1.48
Cell receptors for the mammalian reovirus. I. Syngeneic monoclonal anti-idiotypic antibody identifies a cell surface receptor for reovirus. J Immunol (1983) 1.46
Sequence diversity in S1 genes and S1 translation products of 11 serotype 3 reovirus strains. J Virol (1990) 1.44
Nucleic acid sequence of an internal image-bearing monoclonal anti-idiotype and its comparison to the sequence of the external antigen. Proc Natl Acad Sci U S A (1986) 1.43
Reovirus-specific polypeptides: analysis using discontinuous gel electrophoresis. J Virol (1976) 1.42
Internal/structures containing transcriptase-related proteins in top component particles of mammalian orthoreovirus. Virology (1998) 1.42
Complete nucleotide sequence of the M2 gene segment of reovirus type 3 dearing and analysis of its protein product mu 1. Virology (1988) 1.42
Antibody inhibits defined stages in the pathogenesis of reovirus serotype 3 infection of the central nervous system. J Exp Med (1989) 1.41
Differences between the intracellular polypeptides of measles and subacute sclerosing panencephalitis virus. Nature (1978) 1.41
Role of the S4 gene in the establishment of persistent reovirus infection in L cells. Cell (1982) 1.38
Pathogenesis of viral infections. Basic concepts derived from the reovirus model. N Engl J Med (1985) 1.38
Genetic basis for altered pathogenesis of an immune-selected antigenic variant of reovirus type 3 (Dearing). J Virol (1986) 1.38
Reovirus type 3 encephalitis--a virologic and ultrastructural study. J Neuropathol Exp Neurol (1973) 1.36
Structural similarities between the mammalian beta-adrenergic and reovirus type 3 receptors. Proc Natl Acad Sci U S A (1985) 1.34
Specific disruption of vimentin filament organization in monkey kidney CV-1 cells by diphtheria toxin, exotoxin A, and cycloheximide. Proc Natl Acad Sci U S A (1980) 1.33
A genetic map of reovirus. III. Assignment of the double-stranded RNA-positive mutant groups A, B, and G to genome segments. Virology (1978) 1.31
Human infection with the virus of vesicular stomatitis during an epizootic. N Engl J Med (1967) 1.27