Published in Genes Cells on August 01, 1999
Genomic signatures of human versus avian influenza A viruses. Emerg Infect Dis (2006) 3.51
A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase inhibits endonucleolytic cleavage of capped RNAs. J Virol (2002) 3.37
Host determinant residue lysine 627 lies on the surface of a discrete, folded domain of influenza virus polymerase PB2 subunit. PLoS Pathog (2008) 2.60
The active sites of the influenza cap-dependent endonuclease are on different polymerase subunits. EMBO J (2001) 2.52
Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates. J Virol (2004) 2.49
Persistent host markers in pandemic and H5N1 influenza viruses. J Virol (2007) 2.42
PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells. J Virol (2010) 2.35
Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms. J Biol Chem (2010) 1.89
Complete-proteome mapping of human influenza A adaptive mutations: implications for human transmissibility of zoonotic strains. PLoS One (2010) 1.87
Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature (2014) 1.73
Minimum molecular architectures for transcription and replication of the influenza virus. Proc Natl Acad Sci U S A (2002) 1.70
Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis. BMC Bioinformatics (2008) 1.61
Compatibility among polymerase subunit proteins is a restricting factor in reassortment between equine H7N7 and human H3N2 influenza viruses. J Virol (2008) 1.55
Threonine 157 of influenza virus PA polymerase subunit modulates RNA replication in infectious viruses. J Virol (2003) 1.50
Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrier. J Virol (2013) 1.40
PB2 protein of a highly pathogenic avian influenza virus strain A/chicken/Yamaguchi/7/2004 (H5N1) determines its replication potential in pigs. J Virol (2008) 1.36
NP, PB1, and PB2 viral genes contribute to altered replication of H5N1 avian influenza viruses in chickens. J Virol (2008) 1.34
Mutations in the N-terminal region of influenza virus PB2 protein affect virus RNA replication but not transcription. J Virol (2003) 1.27
Microevolution of highly pathogenic avian influenza A(H5N1) viruses isolated from humans, Egypt, 2007-2011. Emerg Infect Dis (2013) 1.24
Hairpin loop structure in the 3' arm of the influenza A virus virion RNA promoter is required for endonuclease activity. J Virol (2001) 1.23
Adaptive mutations resulting in enhanced polymerase activity contribute to high virulence of influenza A virus in mice. J Virol (2009) 1.18
NP body domain and PB2 contribute to increased virulence of H5N1 highly pathogenic avian influenza viruses in chickens. J Virol (2010) 0.96
Innate immune restriction and antagonism of viral RNA lacking 2׳-O methylation. Virology (2015) 0.95
Expression of functional influenza virus RNA polymerase in the methylotrophic yeast Pichia pastoris. J Virol (2000) 0.90
Upolu virus and Aransas Bay virus, two presumptive bunyaviruses, are novel members of the family Orthomyxoviridae. J Virol (2014) 0.88
Heat shock protein 70 modulates influenza A virus polymerase activity. J Biol Chem (2014) 0.87
Cellular protein HAX1 interacts with the influenza A virus PA polymerase subunit and impedes its nuclear translocation. J Virol (2012) 0.80
Conformational polymorphism of m7GTP in crystal structure of the PB2 middle domain from human influenza A virus. PLoS One (2013) 0.80
Identification of PB2 mutations responsible for the efficient replication of H5N1 influenza viruses in human lung epithelial cells. J Virol (2015) 0.78
Analysis of PB2 protein from H9N2 and H5N1 avian flu virus. Bioinformation (2008) 0.77
Epidemiological and viral genome characteristics of the first human H7N9 influenza infection in Guangdong Province, China. J Thorac Dis (2014) 0.77
Extreme evolutionary conservation of functionally important regions in H1N1 influenza proteome. PLoS One (2013) 0.76
Influenza Virus Infection Induces Host Pyruvate Kinase M Which Interacts with Viral RNA-Dependent RNA Polymerase. Front Microbiol (2017) 0.75
A third recognition element in bacterial promoters: DNA binding by the alpha subunit of RNA polymerase. Science (1993) 7.42
Promoter analysis of influenza virus RNA polymerase. J Virol (1989) 5.66
Growth phase-dependent variation in protein composition of the Escherichia coli nucleoid. J Bacteriol (1999) 5.65
Heterogeneity of the principal sigma factor in Escherichia coli: the rpoS gene product, sigma 38, is a second principal sigma factor of RNA polymerase in stationary-phase Escherichia coli. Proc Natl Acad Sci U S A (1993) 4.92
Bipartite functional map of the E. coli RNA polymerase alpha subunit: involvement of the C-terminal region in transcription activation by cAMP-CRP. Cell (1991) 4.57
RNA polymerase of influenza virus: role of NP in RNA chain elongation. J Biochem (1988) 3.23
Biosynthesis of RNA polymerase in Escherichia coli. I. Control of RNA polymerase content at various growth rates. Mol Gen Genet (1974) 3.15
Regulation of the phosphate regulon of Escherichia coli. Activation of pstS transcription by PhoB protein in vitro. J Mol Biol (1988) 3.14
The minus 35-recognition region of Escherichia coli sigma 70 is inessential for initiation of transcription at an "extended minus 10" promoter. J Mol Biol (1993) 3.08
Twelve species of the nucleoid-associated protein from Escherichia coli. Sequence recognition specificity and DNA binding affinity. J Biol Chem (1999) 3.07
Single-molecule imaging of RNA polymerase-DNA interactions in real time. Biophys J (1999) 3.03
Human ribosomal RNA gene: nucleotide sequence of the transcription initiation region and comparison of three mammalian genes. Proc Natl Acad Sci U S A (1982) 2.89
Systematic sequencing of the Escherichia coli genome: analysis of the 0-2.4 min region. Nucleic Acids Res (1992) 2.75
Regulation of RNA polymerase sigma subunit synthesis in Escherichia coli: intracellular levels of four species of sigma subunit under various growth conditions. J Bacteriol (1996) 2.61
Genetics of bacterial RNA polymerases. Annu Rev Genet (1979) 2.53
Rapid identification of specific genes in E. coli by hybridization to membranes containing the ordered set of phage clones. Biotechniques (1991) 2.51
Regulation of RNA polymerase sigma subunit synthesis in Escherichia coli: intracellular levels of sigma 70 and sigma 38. J Bacteriol (1995) 2.38
Regulation of the Escherichia coli hfq gene encoding the host factor for phage Q beta. J Bacteriol (1994) 2.26
Competition among seven Escherichia coli sigma subunits: relative binding affinities to the core RNA polymerase. Nucleic Acids Res (2000) 2.20
Function and structure of RNA polymerase from vesicular stomatitis virus. J Biol Chem (1976) 2.19
Solution structure of the activator contact domain of the RNA polymerase alpha subunit. Science (1995) 2.17
Functional map of the alpha subunit of Escherichia coli RNA polymerase: two modes of transcription activation by positive factors. Proc Natl Acad Sci U S A (1991) 2.14
Structure and probable genetic location of a "ribosome modulation factor" associated with 100S ribosomes in stationary-phase Escherichia coli cells. Proc Natl Acad Sci U S A (1990) 2.14
mRNA capping enzyme. Isolation and characterization of the gene encoding mRNA guanylytransferase subunit from Saccharomyces cerevisiae. J Biol Chem (1992) 2.12
Two types of localization of the DNA-binding proteins within the Escherichia coli nucleoid. Genes Cells (2000) 2.10
Variation in RNA polymerase sigma subunit composition within different stocks of Escherichia coli W3110. J Bacteriol (1997) 2.08
Mapping the cAMP receptor protein contact site on the alpha subunit of Escherichia coli RNA polymerase. Mol Microbiol (1992) 2.03
In vivo analysis of the promoter structure of the influenza virus RNA genome using a transfection system with an engineered RNA. Proc Natl Acad Sci U S A (1991) 2.03
Messenger RNA capping enzymes from eukaryotic cells. Prog Nucleic Acid Res Mol Biol (1987) 1.98
Selectivity of the Escherichia coli RNA polymerase E sigma 38 for overlapping promoters and ability to support CRP activation. Nucleic Acids Res (1995) 1.98
Transcriptional activation of promoters of the superoxide and multiple antibiotic resistance regulons by Rob, a binding protein of the Escherichia coli origin of chromosomal replication. J Bacteriol (1996) 1.96
Purification and regulatory properties of MarA protein, a transcriptional activator of Escherichia coli multiple antibiotic and superoxide resistance promoters. J Bacteriol (1995) 1.95
Promoter selectivity of prokaryotic RNA polymerases. Trends Genet (1988) 1.93
Reconstitution of influenza virus RNA-nucleoprotein complexes structurally resembling native viral ribonucleoprotein cores. J Biol Chem (1990) 1.89
Determination of the promoter strength in the mixed transcription system: promoters of lactose, tryptophan and ribosomal protein L10 operons from Escherichia coli. Nucleic Acids Res (1983) 1.88
E. coli RNA polymerase, deleted in the C-terminal part of its alpha-subunit, interacts differently with the cAMP-CRP complex at the lacP1 and at the galP1 promoter. Nucleic Acids Res (1993) 1.88
Gallbladder torsion: case report. Abdom Imaging (2001) 1.86
Growth control of influenza A virus by M1 protein: analysis of transfectant viruses carrying the chimeric M gene. J Virol (1994) 1.86
A stationary phase protein in Escherichia coli with binding activity to the major sigma subunit of RNA polymerase. Proc Natl Acad Sci U S A (1998) 1.84
The mediator for stringent control, ppGpp, binds to the beta-subunit of Escherichia coli RNA polymerase. Genes Cells (1998) 1.83
Transcription factor recognition surface on the RNA polymerase alpha subunit is involved in contact with the DNA enhancer element. EMBO J (1996) 1.79
Identification and sequence determination of the host factor gene for bacteriophage Q beta. Nucleic Acids Res (1991) 1.79
Molecular assembly of the influenza virus RNA polymerase: determination of the subunit-subunit contact sites. J Gen Virol (1996) 1.77
Molecular assembly of influenza virus: association of the NS2 protein with virion matrix. Virology (1993) 1.76
Transcription of a recombinant influenza virus RNA in cells that can express the influenza virus RNA polymerase and nucleoprotein genes. J Gen Virol (1992) 1.75
Identification of the RNA polymerase-binding site on genome RNA of influenza virus. J Biochem (1987) 1.73
Promoter selectivity of Escherichia coli RNA polymerase. Differential stringent control of the multiple promoters from ribosomal RNA and protein operons. J Biol Chem (1984) 1.73
Regulation of the Escherichia coli rmf gene encoding the ribosome modulation factor: growth phase- and growth rate-dependent control. EMBO J (1993) 1.72
Promoter selectivity of Escherichia coli RNA polymerase E sigma 70 and E sigma 38 holoenzymes. Effect of DNA supercoiling. J Biol Chem (1996) 1.69
Transmethylation and transguanylylation in 5'-RNA capping system isolated from rat liver nuclei. Proc Natl Acad Sci U S A (1979) 1.66
Subunit of assembly of Escherichia coli RNA polymerase. Adv Biophys (1981) 1.64
Nature of DNA binding and RNA polymerase interaction of the Bordetella pertussis BvgA transcriptional activator at the fha promoter. J Bacteriol (1997) 1.64
Promoter selectivity of Escherichia coli RNA polymerase: effect of base substitutions in the promoter -35 region on promoter strength. Nucleic Acids Res (1990) 1.63
Sendai virus C proteins are categorically nonessential gene products but silencing their expression severely impairs viral replication and pathogenesis. Genes Cells (1998) 1.62
Repression and activation of transcription by Gal and Lac repressors: involvement of alpha subunit of RNA polymerase. EMBO J (1995) 1.60
Interactions between the Escherichia coli cyclic AMP receptor protein and RNA polymerase at class II promoters. Mol Microbiol (1993) 1.60
Correlation between centrosome abnormalities and chromosomal instability in human pancreatic cancer cells. Cancer Genet Cytogenet (2001) 1.60
Functional specialization within the alpha-subunit of Escherichia coli RNA polymerase. J Mol Biol (1991) 1.58
Purification and molecular structure of RNA polymerase from influenza virus A/PR8. J Biochem (1990) 1.57
Heterogeneity of RNA polymerase in Escherichia coli. I. A new holoenzyme containing a new sigma factor. J Mol Biol (1974) 1.56
Positioning of two alpha subunit carboxy-terminal domains of RNA polymerase at promoters by two transcription factors. Proc Natl Acad Sci U S A (1997) 1.56
Transcription activation by the Escherichia coli cyclic AMP receptor protein. Receptors bound in tandem at promoters can interact synergistically. J Mol Biol (1994) 1.56
Interactions between the cyclic AMP receptor protein and the alpha subunit of RNA polymerase at the Escherichia coli galactose operon P1 promoter. Nucleic Acids Res (1994) 1.55
Role of the sigma 70 subunit of Escherichia coli RNA polymerase in transcription activation. J Mol Biol (1994) 1.54
The TyrR protein of Escherichia coli is a class I transcription activator. J Bacteriol (1995) 1.51
Involvement of the RNA polymerase alpha subunit C-terminal region in co-operative interaction and transcriptional activation with OxyR protein. Mol Microbiol (1993) 1.50
Messenger RNA guanylyltransferase from Saccharomyces cerevisiae. Large scale purification, subunit functions, and subcellular localization. J Biol Chem (1987) 1.50
Molecular dissection of influenza virus nucleoprotein: deletion mapping of the RNA binding domain. J Virol (1994) 1.50
Identification of a subunit assembly domain in the alpha subunit of Escherichia coli RNA polymerase. J Mol Biol (1991) 1.47
Identification of the cpdA gene encoding cyclic 3',5'-adenosine monophosphate phosphodiesterase in Escherichia coli. J Biol Chem (1996) 1.46
Mapping of the OxyR protein contact site in the C-terminal region of RNA polymerase alpha subunit. J Bacteriol (1995) 1.46
Flexible linker in the RNA polymerase alpha subunit facilitates the independent motion of the C-terminal activator contact domain. J Mol Biol (1997) 1.46
Promoter determinants for Escherichia coli RNA polymerase holoenzyme containing sigma 38 (the rpoS gene product). Nucleic Acids Res (1995) 1.42
Mechanism for inhibition of influenza virus RNA polymerase activity by matrix protein. J Virol (1996) 1.41
Isolation and characterization of the yeast mRNA capping enzyme beta subunit gene encoding RNA 5'-triphosphatase, which is essential for cell viability. Biochem Biophys Res Commun (1997) 1.41
A novel adenosine triphosphatase isolated from RNA polymerase preparations of Escherichia coli. I. Copurification and separation. J Biochem (1976) 1.40
Heat-shock induction of RNA polymerase sigma-32 synthesis in Escherichia coli: transcriptional control and a multiple promoter system. Mol Gen Genet (1987) 1.40
Transcriptional organization and in vivo role of the Escherichia coli rsd gene, encoding the regulator of RNA polymerase sigma D. J Bacteriol (1999) 1.39
Subunits of RNA polymerase in function and structure. IX. Regulation of RNA polymerase activity by stringent starvation protein (SSP). J Mol Biol (1979) 1.39
Transcriptional organization of the rpsA operon of Escherichia coli. Mol Gen Genet (1984) 1.39
A beta-adrenoceptor agonist evokes a nitric oxide-cGMP relaxation mechanism modulated by adenylyl cyclase in rat aorta. Halothane does not inhibit this mechanism. Anesthesiology (1996) 1.39
Ambidextrous transcriptional activation by SoxS: requirement for the C-terminal domain of the RNA polymerase alpha subunit in a subset of Escherichia coli superoxide-inducible genes. Mol Microbiol (1996) 1.37
Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region. Nucleic Acids Res (1994) 1.36
The C-terminal region of the alpha subunit of Escherichia coli RNA polymerase is required for transcriptional activation of the flagellar level II operons by the FlhD/FlhC complex. J Bacteriol (1995) 1.35
Purification and enzymatic properties of an RNA polymerase-RNA complex from influenza virus. Virus Res (1985) 1.35
Autogenous regulation of RNA polymerase beta subunit synthesis in vitro. J Biol Chem (1978) 1.34
Interferon-inducible mouse Mx1 protein that confers resistance to influenza virus is GTPase. J Biol Chem (1991) 1.34
Identification of an UP element within the IHF binding site at the PL1-PL2 tandem promoter of bacteriophage lambda. J Mol Biol (1996) 1.33
Structure of mouse Mx1 protein. Molecular assembly and GTP-dependent conformational change. J Biol Chem (1993) 1.33
Laparoscopic pancreatic surgery: current indications and surgical results. Surg Endosc (2004) 1.32
Ribosome modulation factor: stationary growth phase-specific inhibitor of ribosome functions from Escherichia coli. Biochem Biophys Res Commun (1995) 1.32
Promoter selectivity of Escherichia coli RNA polymerase sigmaF holoenzyme involved in transcription of flagellar and chemotaxis genes. J Bacteriol (1997) 1.30
Promoter selectivity of Escherichia coli RNA polymerase: alteration by fMet-tRNAfMet. Nucleic Acids Res (1986) 1.29
Biosynthesis of RNA polymerase in Escherichia coli. II. control of RNA polymerase synthesis during nutritional shift up and down. Mol Gen Genet (1975) 1.29
The RNA polymerase PB2 subunit is not required for replication of the influenza virus genome but is involved in capped mRNA synthesis. J Virol (1995) 1.29
The molecular anatomy of influenza virus RNA polymerase. Biol Chem (1997) 1.29
Promoter selectivity control of Escherichia coli RNA polymerase by ionic strength: differential recognition of osmoregulated promoters by E sigma D and E sigma S holoenzymes. Mol Microbiol (1995) 1.28
RNA polymerase mutants of Escherichia coli. Streptolydigin resistance and its relation to rifampicin resistance. Mol Gen Genet (1973) 1.28