Single-molecule imaging of RNA polymerase-DNA interactions in real time.

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Published in Biophys J on February 01, 1999

Authors

Y Harada1, T Funatsu, K Murakami, Y Nonoyama, A Ishihama, T Yanagida

Author Affiliations

1: BioMotron Project, ERATO, JST, Senba-Higashi 2-4-14, Mino, Osaka 562-0035, Japan. harada@phys.keio.ac.jp

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Angiotensinogen-deficient mice with hypotension. J Biol Chem (1994) 2.11

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Promoter selectivity of prokaryotic RNA polymerases. Trends Genet (1988) 1.93

The genetics of bacteriophage SPO1. Biken J (1972) 1.91

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