Isolation and characterization of a near-haploid human cell line.

PubWeight™: 1.66‹?› | Rank: Top 3%

🔗 View Article (PMID 10527618)

Published in Exp Cell Res on November 01, 1999

Authors

M Kotecki1, P S Reddy, B H Cochran

Author Affiliations

1: Department of Physiology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, Massachusetts, 02111, USA.

Articles citing this

Forward and reverse genetics through derivation of haploid mouse embryonic stem cells. Cell Stem Cell (2011) 2.69

Derivation of haploid embryonic stem cells from mouse embryos. Nature (2011) 2.66

High-throughput functional genomics using CRISPR-Cas9. Nat Rev Genet (2015) 2.35

Obligate ligation-gated recombination (ObLiGaRe): custom-designed nuclease-mediated targeted integration through nonhomologous end joining. Genome Res (2012) 2.12

Generation of iPSCs from cultured human malignant cells. Blood (2010) 1.99

Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line. Genome Res (2014) 1.28

Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes. Cell Res (2013) 1.24

Germline potential of parthenogenetic haploid mouse embryonic stem cells. Development (2012) 1.19

A reversible gene trap collection empowers haploid genetics in human cells. Nat Methods (2013) 1.17

Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells. Cell (2015) 1.09

Derivation and characterization of haploid embryonic stem cell cultures in medaka fish. Nat Protoc (2010) 1.01

Fluorescence-based phenotypic selection allows forward genetic screens in haploid human cells. PLoS One (2012) 0.98

Identifying multi-locus chromatin contacts in human cells using tethered multiple 3C. BMC Genomics (2015) 0.92

Haploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligases. PLoS Pathog (2013) 0.90

A unique model system for tumor progression in GBM comprising two developed human neuro-epithelial cell lines with differential transforming potential and coexpressing neuronal and glial markers. Neoplasia (2004) 0.90

A reporter screen in a human haploid cell line identifies CYLD as a constitutive inhibitor of NF-κB. PLoS One (2013) 0.89

Isolation of homozygous mutant mouse embryonic stem cells using a dual selection system. Nucleic Acids Res (2011) 0.88

Exposure of phosphatidylserine on the cell surface. Cell Death Differ (2016) 0.86

Haploid embryonic stem cells: an ideal tool for mammalian genetic analyses. Protein Cell (2012) 0.85

Functional genomics to uncover drug mechanism of action. Nat Chem Biol (2015) 0.82

Comparative Haploid Genetic Screens Reveal Divergent Pathways in the Biogenesis and Trafficking of Glycophosphatidylinositol-Anchored Proteins. Cell Rep (2015) 0.82

Hunting Viral Receptors Using Haploid Cells. Annu Rev Virol (2015) 0.79

A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity. Proc Natl Acad Sci U S A (2015) 0.78

Haploid embryonic stem cells serve as a new tool for mammalian genetic study. Stem Cell Res Ther (2014) 0.78

Application of human haploid cell genetic screening model in identifying the genes required for resistance to environmental toxicants: Chlorpyrifos as a case study. J Pharmacol Toxicol Methods (2015) 0.77

Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens. Nat Commun (2016) 0.77

Haploid genomes illustrate epigenetic constraints and gene dosage effects in mammals. Epigenetics Chromatin (2013) 0.77

NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap4A) and Down-Regulates Immune Response and Cancer Promotion Genes. PLoS One (2016) 0.76

Identification of Genes That Modulate Susceptibility to Formaldehyde and Imatinib by Functional Genomic Screening in Human Haploid KBM7 Cells. Toxicol Sci (2016) 0.76

Genome Editing Using Mammalian Haploid Cells. Int J Mol Sci (2015) 0.76

Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9. Mutat Res Rev Mutat Res (2015) 0.75

Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2. Nat Genet (2017) 0.75

Advances and Challenges on Cancer Cells Reprogramming Using Induced Pluripotent Stem Cells Technologies. J Cancer (2016) 0.75

Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions. J Immunol Res (2017) 0.75

Dissection of splicing regulation at an endogenous locus by zinc-finger nuclease-mediated gene editing. PLoS One (2011) 0.75

Systematic identification of genes involved in metabolic acid stress resistance in yeast and their potential as cancer targets. Dis Model Mech (2016) 0.75

Effects of whole genome duplication on cell size and gene expression in mouse embryonic stem cells. J Reprod Dev (2016) 0.75

Use of a genome-wide haploid genetic screen to identify treatment predicting factors: a proof-of-principle study in pancreatic cancer. Oncotarget (2017) 0.75

Articles by these authors

(truncated to the top 100)

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell (1983) 17.87

Molecular cloning of gene sequences regulated by platelet-derived growth factor. Cell (1983) 9.03

Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor. Science (1984) 4.87

Functional role for c-myc in mitogenic response to platelet-derived growth factor. Nature (1984) 4.56

The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J (1990) 4.28

Ultrasound-assisted cannulation of the internal jugular vein. A prospective comparison to the external landmark-guided technique. Circulation (1993) 3.31

Platelet-derived growth factor and double-stranded ribonucleic acids stimulate expression of the same genes in 3T3 cells. Cell (1985) 2.82

Activation of the JAK-STAT pathway by reactive oxygen species. Am J Physiol (1998) 2.37

Inducible binding of a factor to the c-fos regulatory region. Proc Natl Acad Sci U S A (1987) 2.33

The human c-fos serum response factor and the yeast factors GRM/PRTF have related DNA-binding specificities. Genes Dev (1988) 2.13

p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function. Mol Cell Biol (1999) 1.83

Regulation of STAT3 by direct binding to the Rac1 GTPase. Science (2000) 1.77

Randomized trial of thrombolysis versus heparin in unstable angina. Circulation (1992) 1.74

Development of coronary artery disease in cardiac transplant patients receiving immunosuppressive therapy with cyclosporine and prednisone. Circulation (1987) 1.71

MAT alpha 1 can mediate gene activation by a-mating factor. Genes Dev (1991) 1.58

Health metrics improve childhood immunisation coverage in a rural population of Andhra Pradesh. Indian J Public Health (2009) 1.55

Autonomic mechanisms in hemodynamic responses to isometric exercise. J Clin Invest (1974) 1.51

Utility of prostaglandin E1 in the pretransplantation evaluation of heart failure patients with significant pulmonary hypertension. J Heart Lung Transplant (1992) 1.45

Cardiac tamponade: hemodynamic observations in man. Circulation (1978) 1.45

Direct correlation of external systolic time intervals with internal indices of left ventricular function in man. Circulation (1971) 1.40

Respiratory sinus arrhythmia in the denervated human heart. J Appl Physiol (1985) (1989) 1.39

Coronary artery fistula in the heart transplant patient. A potential complication of endomyocardial biopsy. Circulation (1989) 1.37

TFII-I enhances activation of the c-fos promoter through interactions with upstream elements. Mol Cell Biol (1998) 1.33

Sound pressure correlates of the second heart sound. An intracardiac sound study. Circulation (1974) 1.32

Mycotic keratitis. Indian J Ophthalmol (1972) 1.29

The adverse effect of intravenous iron-dextran in rheumatoid arthritis. Arthritis Rheum (1969) 1.29

p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site. J Biol Chem (1998) 1.23

Growth hormone induces a DNA binding factor related to the interferon-stimulated 91-kDa transcription factor. J Biol Chem (1994) 1.14

The PRE and PQ box are functionally distinct yeast pheromone response elements. Mol Cell Biol (1990) 1.12

Extracellular signal-regulated kinase binds to TFII-I and regulates its activation of the c-fos promoter. Mol Cell Biol (2000) 1.07

The epithelium-specific ETS protein EHF/ESE-3 is a context-dependent transcriptional repressor downstream of MAPK signaling cascades. J Biol Chem (2001) 1.03

Pulsus paradoxus: definition and relation to the severity of cardiac tamponade. Am Heart J (1988) 1.00

Expression of glutathione peroxidase I gene in selenium-deficient rats. Nucleic Acids Res (1988) 1.00

Predisposing risk factors and natural history of acute neurologic complications of left-sided cardiac catheterization. Am J Cardiol (1995) 0.96

Antibacterial activity of the essential oil from Aristolochia indica. Fitoterapia (2002) 0.95

Alterations of right ventricular systolic time intervals by chronic pressure and volume overloading. Circulation (1976) 0.95

Antibacterial activity of Syzygium cumini and Syzygium travancoricum leaf essential oils. Fitoterapia (2002) 0.95

Preoperative pulmonary hemodynamics and early mortality after orthotopic cardiac transplantation: the Pittsburgh experience. Am Heart J (1993) 0.94

JAK2 activates TFII-I and regulates its interaction with extracellular signal-regulated kinase. Mol Cell Biol (2001) 0.94

Isolation and characterization of 5-lipoxygenase from tulip bulbs. Biochem Biophys Res Commun (1988) 0.93

Coordinate expression of c-fos and jun B is induced in the rat striatum by cocaine. J Neurosci (1993) 0.92

Cardiac events after heart transplantation: incidence and predictive value of coronary arteriography. J Heart Lung Transplant (1992) 0.92

A critical appraisal of diastolic time intervals as a measure of relaxation in left ventricular hypertrophy. Circulation (1983) 0.92

Differential colony hybridization: molecular cloning from a zero data base. Methods Enzymol (1987) 0.91

Reversibility of pulmonary hypertension in congestive heart failure patients evaluated for cardiac transplantation: comparative effects of various pharmacologic agents. Am Heart J (1991) 0.90

Heart sound propagation in the human thorax. Clin Phys Physiol Meas (1985) 0.90

Impact of school-based HIV and AIDS education for adolescents in Bombay, India. Southeast Asian J Trop Med Public Health (1996) 0.89

Post-transcriptional control of protein synthesis in Balb/c-3T3 cells by platelet-derived growth factor and platelet-poor plasma. J Cell Physiol (1981) 0.89

The molecular action of platelet-derived growth factor. Adv Cancer Res (1985) 0.89

Sound pressure correlates of the Austin Flint murmur. An intracardiac sound study. Circulation (1976) 0.89

Ultrasonic diagnosis of a choroid plexus neoplasm in a child. Br J Radiol (1984) 0.89

Comparative hemodynamic and hormonal response of enoximone and dobutamine in severe congestive heart failure. Am J Cardiol (1986) 0.88

Comorbidity in juvenile obsessive-compulsive disorder: a report from India. Can J Psychiatry (2000) 0.88

Rapid events in growth hormone action. Induction of c-fos and c-jun transcription in 3T3-F442A preadipocytes. Endocrinology (1990) 0.88

Long-term hemodynamic follow-up of cardiac transplant patients treated with cyclosporine and prednisone. Circulation (1985) 0.88

Subcutaneous and osteolytic rhinosporidiosis. Indian J Pathol Microbiol (1997) 0.88

Determinants of variation between Fick and indicator dilution estimates of cardiac output during diagnostic catheterization. Fick vs. dye cardiac outputs. J Lab Clin Med (1976) 0.88

Intracardiac myxoma in siblings. Chest (1971) 0.88

Construction and characterization of E3-deleted bovine adenovirus type 3 expressing full-length and truncated form of bovine herpesvirus type 1 glycoprotein gD. Virology (1998) 0.87

Shiga toxins activate translational regulation pathways in intestinal epithelial cells. Cell Signal (2004) 0.87

Normal and abnormal heart sounds in cardiac diagnosis. Part I: Systolic sounds. Curr Probl Cardiol (1985) 0.87

Elevation of rat liver mRNA for selenium-dependent glutathione peroxidase by selenium deficiency. J Biol Chem (1990) 0.86

Normal and abnormal heart sounds in cardiac diagnosis: Part II. Diastolic sounds. Curr Probl Cardiol (1985) 0.85

A rapidly inducible DNA-binding activity which binds upstream of the c-fos proto-oncogene. J Cell Physiol Suppl (1987) 0.84

Changing trends in outcome of typhoid ileal perforations over three decades in Pondicherry. Trop Gastroenterol (2001) 0.84

Clinical studies with the new glycosylated recombinant prourokinase. J Vasc Interv Radiol (1996) 0.84

Effect of pigmentation on glutathione redox cycle antioxidant defense in whole as well as different regions of human cataractous lens. Exp Eye Res (1991) 0.84

Aetiological study of the third, fourth and sixth cranial nerve paralysis. Indian J Ophthalmol (1972) 0.84

In vitro allergen challenge of peripheral blood induces differential gene expression in mononuclear cells of asthmatic patients: inhibition of cytosolic phospholipase A2alpha overcomes the asthma-associated response. Clin Exp Allergy (2008) 0.83

Tissue sites of aromatization in the female rhesus monkey. Endocrinology (1983) 0.82

Identification of a PDGF-responsive element in the murine c-myc gene. Oncogene (1990) 0.82

Pleomorphic adenoma of the nasal septum--a case report. Indian J Pathol Microbiol (2004) 0.82

The acute hemodynamic effects of a new agent, MDL 17,043, in the treatment of congestive heart failure. Circulation (1983) 0.81

The third heart sound. Int J Cardiol (1985) 0.81

New recombinant glycosylated prourokinase for treatment of patients with acute myocardial infarction. Prourokinase Study Group. J Am Coll Cardiol (1994) 0.81

Participation of South african youth in the design and development of AIDS photocomics. Int Q Community Health Educ (1997) 0.81

Plasma vasopressin response to osmotic and hemodynamic stimuli in heart failure. Am J Physiol (1985) 0.80

The serum response element can mediate induction of c-fos by growth hormone. Proc Natl Acad Sci U S A (1993) 0.80

MDL 17,043 therapy in severe congestive heart failure: characterization of the early and late hemodynamic, pharmacokinetic, hormonal and clinical response. J Am Coll Cardiol (1985) 0.80

Phonoechocardiography and intracardiac phonocardiography in hypertrophic cardiomyopathy. Postgrad Med J (1986) 0.80

The genesis of gallop sounds: investigation by quantitative phono- and apexcardiography. Circulation (1981) 0.80

Acute hemodynamic and hormonal effects of CI-930, a new phosphodiesterase inhibitor, in severe congestive heart failure. Am J Cardiol (1987) 0.78

An ultrasound method for safe and rapid central venous access. N Engl J Med (1991) 0.78

Value of fluoroscopy in the detection of coronary stenosis: influence of age, sex, and number of vessels calcified on diagnostic efficacy. Am Heart J (1988) 0.78

Combined therapy with dobutamine and amrinone in severe heart failure. Improved hemodynamics and increased activation of the renin-angiotensin system with combined intravenous therapy. Chest (1987) 0.78

Ionic liquids as a reaction medium for lipase-catalyzed methanolysis of sunflower oil. Biotechnol Lett (2007) 0.78

The PDGF-inducible 'competence genes': intracellular mediators of the mitogenic response. Ciba Found Symp (1985) 0.78

Genetic organization and DNA sequence of early region 4 of bovine adenovirus type 3. Virus Genes (1998) 0.78

Positive inotropic therapy for short-term support and long-term management of patients with congestive heart failure: hemodynamic effects and clinical efficacy of MDL 17,043. Circulation (1986) 0.77

Pattern of left ventricular diastolic filling in chronic aortic regurgitation: a gated blood pool assessment. Am J Cardiol (1985) 0.77

Extent of mitral calcific deposits determined by cineangiography in mitral stenosis and their effect on valve motion, hemodynamics and clinical signs. Am J Cardiol (1986) 0.77

Pressure and sound correlates of the mitral valve ecyocardiogram in mitral stenosis. Circulation (1978) 0.77

Potential limitations of percutaneous transluminal coronary angioplasty in heart transplant recipients. Am J Cardiol (1992) 0.77

Acute hemodynamic effect of oral MDL 17,043 in severe congestive heart failure. Am J Cardiol (1984) 0.77

Association of snuff use with chronic bronchitis among South African women: implications for tobacco harm reduction. Tob Control (2008) 0.77

Skeletal scintigraphy in carcinoma of the kidney. Br J Urol (1983) 0.77

Characterization of bovine adenovirus type 3 early region 2B. Virus Genes (1998) 0.76

5S-rRNA genes in rice embryos. Plant Mol Biol (1987) 0.76

Noninvasive/invasive correlates of exaggerated ventricular interdependence in cardiac tamponade. J Cardiol (2001) 0.76

Does non-dysenteric intestinal amoebiasis exist? Lancet (1997) 0.76