Published in J Am Coll Cardiol on November 01, 1994
Highly effective fibrinolysis by a sequential synergistic combination of mini-dose tPA plus low-dose mutant proUK. PLoS One (2015) 0.79
Mutant prourokinase with adjunctive C1-inhibitor is an effective and safer alternative to tPA in rat stroke. PLoS One (2011) 0.78
Why so little progress in therapeutic thrombolysis? The current state of the art and prospects for improvement. J Thromb Thrombolysis (2015) 0.75
Plasma resistance to activated protein C regulates the activation of coagulation induced by thrombolysis in patients with ischaemic heart disease. Heart (1997) 0.75
Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing. Clin Pharmacol Ther (2011) 4.42
A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs. Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators. N Engl J Med (1998) 3.58
Ultrasound-assisted cannulation of the internal jugular vein. A prospective comparison to the external landmark-guided technique. Circulation (1993) 3.31
Clinical use of the total artificial heart. N Engl J Med (1984) 2.94
A randomized trial of intracoronary streptokinase in the treatment of acute myocardial infarction. N Engl J Med (1983) 2.85
ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). J Am Coll Cardiol (1996) 2.81
The "on-off" phenomenon in Parkinson's disease. Relation to levodopa absorption and transport. N Engl J Med (1984) 2.71
An emergency department-based protocol for rapidly ruling out myocardial ischemia reduces hospital time and expense: results of a randomized study (ROMIO). J Am Coll Cardiol (1996) 2.46
Restricted transport in small pores. A model for steric exclusion and hindered particle motion. Biophys J (1974) 2.42
The long QT syndromes: a critical review, new clinical observations and a unifying hypothesis. Prog Cardiovasc Dis (1988) 2.42
Bone-marrow transplantation in a patient with the Wiskott-Aldrich syndrome. Lancet (1968) 2.29
HLA class II (DR and DQ) antigen associations in idiopathic dilated cardiomyopathy. Validation study and meta-analysis of published HLA association studies. Circulation (1991) 2.22
Integration of genetic, clinical, and INR data to refine warfarin dosing. Clin Pharmacol Ther (2010) 2.21
Time delays in the diagnosis and treatment of acute myocardial infarction: a tale of eight cities. Report from the Pre-hospital Study Group and the Cincinnati Heart Project. Am Heart J (1990) 2.14
Association of androgenic-anabolic steroid therapy with development of hepatocellular carcinoma. Lancet (1972) 2.13
Mechanism of osmotic flow in porous membranes. Biophys J (1974) 2.07
Oral flecainide acetate for the treatment of ventricular arrhythmias. N Engl J Med (1981) 1.99
Cytomegalovirus seropositivity and C-reactive protein have independent and combined predictive value for mortality in patients with angiographically demonstrated coronary artery disease. Circulation (2000) 1.92
Standardized full-field electroretinography. Normal values and their variation with age. Arch Ophthalmol (1992) 1.92
Clinical and physiologic studies in pulmonary thromboembolism. Am J Cardiol (1967) 1.91
Coronary spasm producing coronary thrombosis and myocardial infarction. N Engl J Med (1983) 1.91
Idiopathic cardiomyopathy, age, and suppressor-cell dysfunction as risk determinants of lymphoma after cardiac transplantation. Lancet (1978) 1.87
Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model. Circulation (1998) 1.86
Effect of thrombolytic therapy on pulmonary-capillary blood volume in patients with pulmonary embolism. N Engl J Med (1980) 1.80
Yearly rates of rod and cone functional loss in retinitis pigmentosa and cone-rod dystrophy. Ophthalmology (1999) 1.80
Randomized secondary prevention trial of azithromycin in patients with coronary artery disease: primary clinical results of the ACADEMIC study. Circulation (2000) 1.74
Randomized trial of thrombolysis versus heparin in unstable angina. Circulation (1992) 1.74
Angiotensin-converting enzyme gene polymorphism is associated with myocardial infarction but not with development of coronary stenosis. Circulation (1995) 1.73
Development of coronary artery disease in cardiac transplant patients receiving immunosuppressive therapy with cyclosporine and prednisone. Circulation (1987) 1.71
Thrombolysis or peripheral arterial surgery: phase I results. TOPAS Investigators. J Vasc Surg (1996) 1.70
Implementation of a computerized cardiovascular information system in a private hospital setting. Am Heart J (1998) 1.68
Isolation and characterization of a near-haploid human cell line. Exp Cell Res (1999) 1.66
S-cone function in patients with retinitis pigmentosa. Invest Ophthalmol Vis Sci (1993) 1.65
Patient information recall in a rheumatology clinic. Rheumatol Rehabil (1979) 1.62
Prospective study of pathogen burden and risk of myocardial infarction or death. Circulation (2001) 1.61
Flecainide acetate prevents recurrence of symptomatic paroxysmal supraventricular tachycardia. The Flecainide Supraventricular Tachycardia Study Group. Circulation (1991) 1.59
HLA haplotypes in a family with multiple cases of rheumatoid arthritis. J Rheumatol (1982) 1.59
Health metrics improve childhood immunisation coverage in a rural population of Andhra Pradesh. Indian J Public Health (2009) 1.55
Increased incidence of Chlamydia species within the coronary arteries of patients with symptomatic atherosclerotic versus other forms of cardiovascular disease. J Am Coll Cardiol (1996) 1.55
Thrombolytic therapy. N Engl J Med (1982) 1.54
Dihydroergotamine/heparin in the prevention of deep-vein thrombosis after total hip replacement. A controlled, prospective, randomized multicenter trial. J Bone Joint Surg Am (1988) 1.53
Autonomic mechanisms in hemodynamic responses to isometric exercise. J Clin Invest (1974) 1.51
Vitamin K deficiency in infants beyond the neonatal period. J Pediatr (1970) 1.48
Partitioning and diffusion of proteins and linear polymers in polyacrylamide gels. Biophys J (1996) 1.46
The electrocardiogram in acute pulmonary embolism. Prog Cardiovasc Dis (1975) 1.46
Utility of prostaglandin E1 in the pretransplantation evaluation of heart failure patients with significant pulmonary hypertension. J Heart Lung Transplant (1992) 1.45
Changes in spontaneous variability of ventricular ectopic activity as a function of time in patients with chronic arrhythmias. Circulation (1988) 1.45
Cardiac tamponade: hemodynamic observations in man. Circulation (1978) 1.45
Patient preferences and the bedside manner. Med Educ (1982) 1.41
Direct correlation of external systolic time intervals with internal indices of left ventricular function in man. Circulation (1971) 1.40
Respiratory sinus arrhythmia in the denervated human heart. J Appl Physiol (1985) (1989) 1.39
Use of aortic counterpulsation to improve sustained coronary artery patency during acute myocardial infarction. Results of a randomized trial. The Randomized IABP Study Group. Circulation (1994) 1.39
The hemodynamic response to pulmonary embolism in patients without prior cardiopulmonary disease. Am J Cardiol (1971) 1.38
Genetics informatics trial (GIFT) of warfarin to prevent deep vein thrombosis (DVT): rationale and study design. Pharmacogenomics J (2011) 1.38
Coronary artery fistula in the heart transplant patient. A potential complication of endomyocardial biopsy. Circulation (1989) 1.37
Nuclear preparations of SV40-transformed cells contain tumor-specific transplantation antigen activity. Virology (1977) 1.37
Urokinase therapy in clinical pulmonary embolism. A new thrombolytic agent. N Engl J Med (1967) 1.36
Biobehavioral variables and mortality or cardiac arrest in the Cardiac Arrhythmia Pilot Study (CAPS). Am J Cardiol (1990) 1.35
Sound pressure correlates of the second heart sound. An intracardiac sound study. Circulation (1974) 1.32
Mycotic keratitis. Indian J Ophthalmol (1972) 1.29
The adverse effect of intravenous iron-dextran in rheumatoid arthritis. Arthritis Rheum (1969) 1.29
Thrombolysis and myocardial salvage. Results of clinical trials and the animal paradigm--paradoxic or predictable? Circulation (1993) 1.28
Reduction in QT interval dispersion by successful thrombolytic therapy in acute myocardial infarction. TEAM-2 Study Investigators. Circulation (1994) 1.26
Malignant neoplasms following cardiac transplantation. JAMA (1978) 1.24
Usefulness of in-hospital prescription of statin agents after angiographic diagnosis of coronary artery disease in improving continued compliance and reduced mortality. Am J Cardiol (2001) 1.24
Risk factors for congenital hypothyroidism: an investigation of infant's birth weight, ethnicity, and gender in California, 1990-1998. Teratology (2000) 1.23
Treatment of breast cancer: doctor/patient communication and psychosocial implications. Proc R Soc Med (1975) 1.23
Model pores of molecular dimension. The preparation and characterization of track-etched membranes. Biophys J (1972) 1.21
Kinetics and yield of singlet oxygen photosensitized by hypericin in organic and biological media. Photochem Photobiol (1998) 1.21
The role of combined chemotherapy in the treatment of rhabdomyosarcoma in children. Cancer (1974) 1.21
Statin therapy, lipid levels, C-reactive protein and the survival of patients with angiographically severe coronary artery disease. J Am Coll Cardiol (2000) 1.20
A randomized trial of intravenous and intracoronary streptokinase in patients with acute myocardial infarction. Circulation (1984) 1.19
Coffee consumption and cause-specific mortality. Association with age at death and compression of mortality. J Clin Epidemiol (1992) 1.17
Expression and thermal stability of simian virus 40 tumor-specific transplantation antigen and tumor antigen in wild type- and tsA mutant-transformed cells. J Virol (1977) 1.15
Neutrophil dysfunction in diabetes mellitus. J Lab Clin Med (1975) 1.15
SV40 transformation of mouse brain cells: critical role of gene A in maintenance of the transformed phenotype. J Cell Physiol (1976) 1.14
Generating genetic risk scores from intermediate phenotypes for use in association studies of clinically significant endpoints. Ann Hum Genet (2005) 1.13
The effect of carbidopa on the pharmacokinetics of intravenously administered levodopa: the mechanism of action in the treatment of parkinsonism. Ann Neurol (1985) 1.13
HLA A, B and DR typing in idiopathic dilated cardiomyopathy: a search for immune response factors. Am J Cardiol (1984) 1.13
Vancomycin pharmacokinetics, renal handling, and nonrenal clearances in normal human subjects. Clin Pharmacol Ther (1988) 1.12
Novel cardiac troponin T mutation as a cause of familial dilated cardiomyopathy. Circulation (2001) 1.12
A randomized trial of low-dose beta-blockade therapy for idiopathic dilated cardiomyopathy. Am J Cardiol (1985) 1.08
Long-term beta-blocker vasodilator therapy improves cardiac function in idiopathic dilated cardiomyopathy: a double-blind, randomized study of bucindolol versus placebo. Am J Med (1990) 1.08
Hamstrings vs. patella tendon for anterior cruciate ligament reconstruction: a randomised controlled trial. Knee (2001) 1.08
Liver laceration in the hemodynamically unstable post-cardiac massage patient: early recognition and management--case report. J Trauma (1999) 1.07
Impact of field-transmitted electrocardiography on time to in-hospital thrombolytic therapy in acute myocardial infarction. Am J Cardiol (1990) 1.07
Classification by type of ventricular arrhythmia predicts frequency of adverse cardiac events from flecainide. J Am Coll Cardiol (1986) 1.07
Treatment of ventricular arrhythmias by United States cardiologists: a survey before the Cardiac Arrhythmia Suppression Trial results were available. Am J Cardiol (1990) 1.06
Genetic mapping of a novel familial form of infantile hemangioma. Am J Med Genet (1999) 1.05
The epithelium-specific ETS protein EHF/ESE-3 is a context-dependent transcriptional repressor downstream of MAPK signaling cascades. J Biol Chem (2001) 1.03
Lack of influence of pretreatment antistreptokinase antibody on efficacy in a multicenter patency comparison of intravenous streptokinase and anistreplase in acute myocardial infarction. Am Heart J (1992) 1.03
Safety and tolerability of long-term propafenone therapy for supraventricular tachyarrhythmias. The Propafenone Multicenter Study Group. Am J Cardiol (1996) 1.03
Pulsus paradoxus: definition and relation to the severity of cardiac tamponade. Am Heart J (1988) 1.00
Development of an in vivo model of human multiple myeloma bone disease. Blood (1996) 1.00