Catalytic mechanism of phosphorylase kinase probed by mutational studies.

PubWeight™: 0.95‹?› | Rank: Top 15%

🔗 View Article (PMID 10545198)

Published in Biochemistry on November 02, 1999

Authors

V T Skamnaki1, D J Owen, M E Noble, E D Lowe, G Lowe, N G Oikonomakos, L N Johnson

Author Affiliations

1: Institute for Biological Research and Biotechnology, Athens, Greece.

Articles citing this

Cytoskeletal protein kinases: titin and its relations in mechanosensing. Pflugers Arch (2011) 1.46

Phosphorylation of the protein kinase C-theta activation loop and hydrophobic motif regulates its kinase activity, but only activation loop phosphorylation is critical to in vivo nuclear-factor-kappaB induction. Biochem J (2002) 1.41

Using reaction mechanism to measure enzyme similarity. J Mol Biol (2007) 1.04

How does activation loop phosphorylation modulate catalytic activity in the cAMP-dependent protein kinase: a theoretical study. Protein Sci (2006) 1.04

Characterization of the purified hyaluronan synthase from Streptococcus equisimilis. Biochemistry (2004) 0.99

The structure of phosphorylase kinase holoenzyme at 9.9 angstroms resolution and location of the catalytic subunit and the substrate glycogen phosphorylase. Structure (2009) 0.91

Identification of a hidden strain switch provides clues to an ancient structural mechanism in protein kinases. Proc Natl Acad Sci U S A (2012) 0.88

Mutations in the catalytic loop HRD motif alter the activity and function of Drosophila Src64. PLoS One (2011) 0.87

Regulatory phosphorylation of cyclin-dependent kinase 2: insights from molecular dynamics simulations. J Mol Model (2008) 0.81

A QM/MM study of the associative mechanism for the phosphorylation reaction catalyzed by protein kinase A and its D166A mutant. J Comput Aided Mol Des (2014) 0.76

Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases. Mol Cell (2016) 0.76

A new autoinhibited kinase conformation reveals a salt-bridge switch in kinase activation. Sci Rep (2016) 0.75

The regulatory α and β subunits of phosphorylase kinase directly interact with its substrate, glycogen phosphorylase. Biochem Biophys Res Commun (2016) 0.75

Bypass of activation loop phosphorylation by aspartate 836 in activation of the endoribonuclease activity of Ire1. Mol Cell Biol (2017) 0.75

Articles by these authors

Active and inactive protein kinases: structural basis for regulation. Cell (1996) 7.98

Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes. Science (2001) 5.45

Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function. EMBO J (1991) 4.59

Crystallographic studies of the activity of hen egg-white lysozyme. Proc R Soc Lond B Biol Sci (1967) 4.25

The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases. Nat Cell Biol (1999) 3.83

Primary prevention for alcohol misuse in young people. Cochrane Database Syst Rev (2002) 2.80

Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice. Neuron (2000) 2.73

Longer-term primary prevention for alcohol misuse in young people: a systematic review. Addiction (2003) 2.67

A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain. Cell (1999) 2.65

The proton flux through the bacterial flagellar motor. Cell (1987) 2.56

The structure of ribonuclease-S at 3.5 A resolution. J Biol Chem (1967) 2.33

The crystal structure of cyclin A. Structure (1995) 2.28

Evidence for histidine in the active site of papain. Biochem J (1968) 2.16

Structural changes in glycogen phosphorylase induced by phosphorylation. Nature (1988) 2.16

The Eleventh Datta Lecture. The structural basis for substrate recognition and control by protein kinases. FEBS Lett (1998) 2.15

Tanning with ultraviolet A sunbeds. BMJ (1990) 1.93

Influence of age-related maculopathy on visual functioning and health-related quality of life. Am J Ophthalmol (1999) 1.86

The allosteric transition of glycogen phosphorylase. Nature (1989) 1.84

Isolated inferior oblique paresis from brain-stem infarction. Perspective on oculomotor fascicular organization in the ventral midbrain tegmentum. Arch Neurol (1990) 1.80

Structure of arylamine N-acetyltransferase reveals a catalytic triad. Nat Struct Biol (2000) 1.72

Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP. J Mol Biol (1991) 1.70

A comparison of the associations between seven hemostatic or inflammatory variables and coronary heart disease. J Thromb Haemost (2007) 1.69

The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition. EMBO J (1997) 1.68

Structure of some crystalline lysozyme-inhibitor complexes determined by X-ray analysis at 6 Angstrom resolution. Nature (1965) 1.68

Kinetic specificity in papain-catalysed hydrolyses. Biochem J (1971) 1.60

Catalysis in the crystal: synchrotron radiation studies with glycogen phosphorylase b. EMBO J (1987) 1.60

Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2. Mol Cell (2001) 1.59

Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity. J Biol Chem (1999) 1.56

Design of a diffractometer and flow cell system for X-ray analysis of crystalline proteins with applications to the crystal chemistry of ribonuclease-S. J Mol Biol (1967) 1.56

Cyclin-dependent kinases: inhibition and substrate recognition. Curr Opin Struct Biol (1999) 1.52

Formation of precise connections in the olfactory bulb occurs in the absence of odorant-evoked neuronal activity. Neuron (2000) 1.52

Sphenoid sinus mucocele (anterior clinoid variant) mimicking diabetic ophthalmoplegia and retrobulbar neuritis. Am J Ophthalmol (1986) 1.51

Refined 1.83 A structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 M-ammonium sulphate. A comparison with the structure of the trypanosomal triosephosphate isomerase-glycerol-3-phosphate complex. J Mol Biol (1991) 1.50

Optic nerve compression by a dolichoectatic internal carotid artery: case report. Neurosurgery (1996) 1.46

The location of the active-site histidine residue in the primary sequence of papain. Biochem J (1968) 1.44

Crystal structure of a lysozyme-tetrasaccharide lactone complex. J Mol Biol (1974) 1.43

A systematic review of drug-induced subacute cutaneous lupus erythematosus. Br J Dermatol (2011) 1.42

Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product. Structure (1995) 1.41

Sinus tumors invading the orbit. Ophthalmology (1984) 1.38

The cyclin box fold: protein recognition in cell-cycle and transcription control. Trends Biochem Sci (1997) 1.34

Comparison of the refined crystal structures of liganded and unliganded chicken, yeast and trypanosomal triosephosphate isomerase. J Mol Biol (1992) 1.33

The crystal structure of triacylglycerol lipase from Pseudomonas glumae reveals a partially redundant catalytic aspartate. FEBS Lett (1993) 1.32

Protein-oligosaccharide interactions: lysozyme, phosphorylase, amylases. Curr Top Microbiol Immunol (1988) 1.30

Investigation of the active site of papain with fluorescent probes. Biochem J (1973) 1.30

Beta-lactamase inhibitors. The inhibition of serine beta-lactamases by specific boronic acids. Biochem J (1988) 1.29

Association of IL-10 polymorphism with severity of illness in community acquired pneumonia. Thorax (2003) 1.28

The amino acid sequence around the active-site cysteine and histidine residues, and the buried cysteine residue in ficin. Biochem J (1970) 1.26

Completion of the amino acid sequence of papain. Biochem J (1969) 1.24

Clathrin coat construction in endocytosis. Curr Opin Struct Biol (2000) 1.22

The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases. J Biol Chem (2001) 1.21

The crystal structure of N-acetyl-alpha-D-glucosamine. Acta Crystallogr (1966) 1.20

Human Dermo-1 has attributes similar to twist in early bone development. Bone (2000) 1.20

Overexpression of trypanosomal triosephosphate isomerase in Escherichia coli and characterisation of a dimer-interface mutant. Eur J Biochem (1993) 1.19

pH-dependence and structure-activity relationships in the papain-catalysed hydrolysis of anilides. Biochem J (1971) 1.19

The structure of ribonuclease-S at 6 A resolution. J Biol Chem (1967) 1.18

The crystal structure of the "open" and the "closed" conformation of the flexible loop of trypanosomal triosephosphate isomerase. Proteins (1991) 1.17

Adolescent drinking behaviour and family socialization factors: a meta-analysis. J Adolesc (1991) 1.17

Subunit structure of aldolase: chemical and crystallographic evidence. J Mol Biol (1969) 1.17

Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b. Biochemistry (1990) 1.16

Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2. Nat Struct Biol (1997) 1.16

The crystal structure of Escherichia coli maltodextrin phosphorylase provides an explanation for the activity without control in this basic archetype of a phosphorylase. EMBO J (1997) 1.14

Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles. J Med Chem (2000) 1.13

Phosphatidylinositol synthase and phosphatidylinositol/inositol exchange reactions in turkey erythrocyte membranes. Biochem J (1991) 1.13

A new allosteric site in glycogen phosphorylase b as a target for drug interactions. Structure (2000) 1.12

Crystallographic studies on the activity of glycogen phosphorylase b. Nature (1978) 1.12

Physical structure, genetic content and expression of the alkBAC operon. Mol Gen Genet (1984) 1.10

Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switch. Proc Natl Acad Sci U S A (1995) 1.10

Hen egg white lysozyme expressed in, and secreted from, Aspergillus niger is correctly processed and folded. Biotechnology (N Y) (1990) 1.09

The crystal structure of p13suc1, a p34cdc2-interacting cell cycle control protein. EMBO J (1995) 1.08

The amino acid sequence around the active-site cysteine and histidine residues of stem bromelain. Biochem J (1970) 1.07

Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: structural basis of antifolate resistance. Bioorg Med Chem (2000) 1.07

Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question. EMBO J (1999) 1.07

Alcohol misuse prevention for young people: a systematic review reveals methodological concerns and lack of reliable evidence of effectiveness. Addiction (1997) 1.06

A reinvestigation of residues 64-68 and 175 in papain. Evidence that residues 64 and 175 are asparagine. Biochem J (1970) 1.05

Suppression of odorant responses by odorants in olfactory receptor cells. Science (1994) 1.04

Oligosaccharide substrate binding in Escherichia coli maltodextrin phosphorylase. Nat Struct Biol (1997) 1.04

Monocular elevation paresis and incomplete ptosis due to midbrain infarction involving the fascicular segment of the oculomotor nerve. J Clin Neuroophthalmol (1992) 1.04

Substrate-cofactor interactions for glycogen phosphorylase b: a binding study in the crystal with heptenitol and heptulose 2-phosphate. Biochemistry (1984) 1.04

Changes in absorption spectrum and crystal structure of triose phosphate isomerase brought about by 2-phosphoglycollate, a potential transition state analogue. J Mol Biol (1970) 1.04

Bioorganic synthesis of lipid-modified proteins for the study of signal transduction. Nature (2000) 1.03

Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds. Biochemistry (1994) 1.02

Enzymatic catalysis in crystals of Escherichia coli maltodextrin phosphorylase. J Mol Biol (2002) 1.02