Published in Am J Psychiatry on November 01, 1999
Behavioral models of impulsivity in relation to ADHD: translation between clinical and preclinical studies. Clin Psychol Rev (2006) 2.96
The neuropsychopharmacology of action inhibition: cross-species translation of the stop-signal and go/no-go tasks. Psychopharmacology (Berl) (2008) 2.07
Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. J Neurosci (2009) 2.04
Serotonin and dopamine: unifying affective, activational, and decision functions. Neuropsychopharmacology (2010) 1.87
Similarities and differences between pathological gambling and substance use disorders: a focus on impulsivity and compulsivity. Psychopharmacology (Berl) (2011) 1.77
Is there an inhibitory-response-control system in the rat? Evidence from anatomical and pharmacological studies of behavioral inhibition. Neurosci Biobehav Rev (2009) 1.74
Involvement of a polymorphism in the 5-HT2A receptor gene in impulsive behavior. Psychopharmacology (Berl) (2006) 1.51
Stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-HT theory of impulsivity. Psychopharmacology (Berl) (2005) 1.43
Serotonin, inhibition, and negative mood. PLoS Comput Biol (2008) 1.39
The utility of rat models of impulsivity in developing pharmacotherapies for impulse control disorders. Br J Pharmacol (2011) 1.39
L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications. Int J Tryptophan Res (2009) 1.29
Individual differences in threat sensitivity predict serotonergic modulation of amygdala response to fearful faces. Psychopharmacology (Berl) (2005) 1.27
The effect of acute tryptophan depletion on the BOLD response during performance monitoring and response inhibition in healthy male volunteers. Psychopharmacology (Berl) (2006) 1.26
Opposing effects of 5-HT(2A) and 5-HT(2C) receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test. Psychopharmacology (Berl) (2007) 1.21
Recent research on impulsivity in individuals with drug use and mental health disorders: implications for alcoholism. Alcohol Clin Exp Res (2010) 1.19
Effects of family history of alcohol use disorders on spatial working memory BOLD response in adolescents. Alcohol Clin Exp Res (2008) 1.15
Elevated impulsivity and impaired decision-making cognition in heavy users of MDMA ("Ecstasy"). Psychopharmacology (Berl) (2006) 1.12
Disrupted 'reflection' impulsivity in cannabis users but not current or former ecstasy users. J Psychopharmacol (2008) 1.10
The effects of acute tryptophan depletion and serotonin transporter polymorphism on emotional processing in memory and attention. Int J Neuropsychopharmacol (2006) 1.10
Serotonin at the nexus of impulsivity and cue reactivity in cocaine addiction. Neuropharmacology (2013) 1.05
Effects of acute tryptophan depletion on prefrontal-amygdala connectivity while viewing facial signals of aggression. Biol Psychiatry (2011) 1.04
Mood-elevating effects of d-amphetamine and incentive salience: the effect of acute dopamine precursor depletion. J Psychiatry Neurosci (2007) 1.03
Serotonin depletion induces 'waiting impulsivity' on the human four-choice serial reaction time task: cross-species translational significance. Neuropsychopharmacology (2014) 0.99
Revisiting the serotonin-aggression relation in humans: a meta-analysis. Psychol Bull (2013) 0.94
The short (S) allele of the serotonin transporter polymorphism and acute tryptophan depletion both increase impulsivity in men. Neurosci Lett (2010) 0.91
The effects of alcohol on laboratory-measured impulsivity after L: -Tryptophan depletion or loading. Psychopharmacology (Berl) (2007) 0.90
Selective serotonin reuptake inhibition modulates response inhibition in Parkinson's disease. Brain (2014) 0.89
Estimates of regional cerebral blood flow and 5-HT2A receptor density in impulsive, aggressive dogs with 99mTc-ECD and 123I-5-I-R91150. Eur J Nucl Med Mol Imaging (2003) 0.89
Neuropsychological function in ecstasy users: a study controlling for polydrug use. Psychopharmacology (Berl) (2005) 0.88
Serotonin augmentation reduces response to attack in aggressive individuals. Psychol Sci (2009) 0.87
Brain serotonin synthesis in adult males characterized by physical aggression during childhood: a 21-year longitudinal study. PLoS One (2010) 0.86
Effect of tryptophan depletion on the attentional salience of smoking cues. Psychopharmacology (Berl) (2007) 0.86
Acute tryptophan depletion and self-injurious behavior in aggressive patients and healthy volunteers. Psychopharmacology (Berl) (2008) 0.85
Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology. J Psychiatry Neurosci (2015) 0.84
Behavioral and neurological foundations for the moral and legal implications of intoxication, addictive behaviors and disinhibition. Behav Sci Law (2009) 0.83
Effects of acute tryptophan depletion on three different types of behavioral impulsivity. Int J Tryptophan Res (2010) 0.81
The effects of acute tryptophan depletion on reactive aggression in adults with attention-deficit/hyperactivity disorder (ADHD) and healthy controls. PLoS One (2012) 0.80
Mismatch negativity: no difference between controls and abstinent alcoholics. Alcohol Clin Exp Res (2004) 0.80
Mismatch negativity: no difference between treatment-naive alcoholics and controls. Alcohol Clin Exp Res (2004) 0.79
Effects of tryptophan depletion and a simulated alcohol binge on impulsivity. Exp Clin Psychopharmacol (2015) 0.77
Acute tryptophan depletion and sweet food consumption by overweight adults. Eat Behav (2008) 0.77
Drinking histories in alcohol-use-disordered youth: preliminary findings on relationships to platelet serotonin transporter expression with genotypes of the serotonin transporter. J Stud Alcohol Drugs (2009) 0.77
Effects of escitalopram on attentional bias to cocaine-related stimuli and inhibitory control in cocaine-dependent subjects. J Psychopharmacol (2013) 0.77
Involvement of serotonin transporter gene polymorphisms (5-HTT) in impulsive behavior in the japanese population. PLoS One (2015) 0.76
Studying the effects of dietary body weight-adjusted acute tryptophan depletion on punishment-related behavioral inhibition. Food Nutr Res (2015) 0.76
Recent Insights into the Neurobiology of Impulsivity. Curr Addict Rep (2014) 0.76
The effect of acute tryptophan depletion on mood and impulsivity in polydrug ecstasy users. Psychopharmacology (Berl) (2013) 0.76
Effects of quetiapine and olanzapine in patients with psychosis and violent behavior: a pilot randomized, open-label, comparative study. Neuropsychiatr Dis Treat (2014) 0.75
Tryptophan depletion affects compulsive behaviour in rats: strain dependent effects and associated neuromechanisms. Psychopharmacology (Berl) (2017) 0.75
Risk factors for suicide completion in major depression: a case-control study of impulsive and aggressive behaviors in men. Am J Psychiatry (2005) 2.54
Differences between males and females in rates of serotonin synthesis in human brain. Proc Natl Acad Sci U S A (1997) 2.50
Prediction of level of serotonin 2A receptor binding by serotonin receptor 2A genetic variation in postmortem brain samples from subjects who did or did not commit suicide. Am J Psychiatry (1999) 2.45
Functional associations among trauma, PTSD, and substance-related disorders. Addict Behav (1999) 2.24
A bimodal preventive intervention for disruptive kindergarten boys: its impact through mid-adolescence. J Consult Clin Psychol (1995) 2.23
Predicting early onset of male antisocial behavior from preschool behavior. Arch Gen Psychiatry (1994) 2.09
Tryptophan depletion causes a rapid lowering of mood in normal males. Psychopharmacology (Berl) (1985) 2.02
Polyglutamine-containing proteins in schizophrenia. Mol Psychiatry (1999) 1.77
Acute alcohol intoxication and cognitive functioning. J Stud Alcohol (1990) 1.73
A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior. Mol Psychiatry (2003) 1.58
Effect on mood of subthalamic DBS for Parkinson's disease: a consecutive series of 24 patients. Neurology (2002) 1.53
Current directions in research on understanding and preventing intoxicated aggression. Addiction (1998) 1.53
Anxiety sensitivity and self-reported reasons for drug use. J Subst Abuse (1997) 1.47
Patterns of gene expression in the limbic system of suicides with and without major depression. Mol Psychiatry (2007) 1.47
Alcohol and crimes of violence: present issues. Int J Addict (1990) 1.42
A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders. Mol Psychiatry (2003) 1.37
Serotonin and alcohol intake, abuse, and dependence: clinical evidence. Biol Psychiatry (1994) 1.34
Hair element content in learning disabled children. Science (1977) 1.33
Serotonin and alcohol intake, abuse, and dependence: findings of animal studies. Biol Psychiatry (1994) 1.32
Morphine-6-glucuronide: analgesic effects and receptor binding profile in rats. Life Sci (1988) 1.31
Anxiety, antisocial behavior, and heart rate regulation in adolescent males. J Child Psychol Psychiatry (1997) 1.31
Elevated dopa decarboxylase activity in living brain of patients with psychosis. Proc Natl Acad Sci U S A (1994) 1.30
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies. Brain Res (1974) 1.29
Folate deficiency and decreased brain 5-hydroxytryptamine synthesis in man and rat. Nature (1979) 1.26
Mechanism of decline in rat brain 5-hydroxytryptamine after induction of liver tryptophan pyrrolase by hydrocortisone: roles of tryptophan catabolism and kynurenine synthesis. Br J Pharmacol (1981) 1.25
Mood-lowering effect of tryptophan depletion. Enhanced susceptibility in young men at genetic risk for major affective disorders. Arch Gen Psychiatry (1994) 1.24
Respiration-dependent uptake of dihydrostreptomycin by Escherichia coli. Its irreversible nature and lack of evidence for a uniport process. Biochem J (1985) 1.23
Reliability and validity of alcohol-induced heart rate increase as a measure of sensitivity to the stimulant properties of alcohol. Psychopharmacology (Berl) (2001) 1.23
Cerebral glucose metabolic rates in obsessive compulsive disorder. Neuropsychopharmacology (1989) 1.23
"Sucrose analgesia" and diphtheria-tetanus-pertussis immunizations at 2 and 4 months. J Dev Behav Pediatr (1995) 1.21
Differential sensitivity to alcohol reinforcement in groups of men at risk for distinct alcoholism subtypes. Alcohol Clin Exp Res (1998) 1.19
Effect of 5-hydroxytryptamine precursors on morphine analgesia in the formalin test. Pharmacol Biochem Behav (1988) 1.19
Familial restless legs with periodic movements in sleep: electrophysiologic, biochemical, and pharmacologic study. Neurology (1985) 1.17
Tryptophan, 5-hydroxyindoleacetic acid and indoleacetic acid in human cerebrospinal fluid: interrelationships and the influence of age, sex, epilepsy and anticonvulsant drugs. J Neurol Neurosurg Psychiatry (1980) 1.16
The effect of tryptophan on social interaction in everyday life: a placebo-controlled study. Neuropsychopharmacology (2001) 1.15
Efficacy of brief coping skills interventions that match different personality profiles of female substance abusers. Psychol Addict Behav (2000) 1.15
Vertebrae transferrins. Molecular weights, chemical compositions, and iron-binding studies. Biochemistry (1971) 1.13
Stress and depressed mood in medical students, law students, and graduate students at McGill University. Acad Med (1997) 1.13
The response of crying newborns to sucrose: is it a "sweetness" effect? Physiol Behav (1999) 1.10
T102C polymorphism in the 5HT2A gene and schizophrenia: relation to phenotype and drug response variability. J Psychiatry Neurosci (1999) 1.10
Tryptophan depletion, executive functions, and disinhibition in aggressive, adolescent males. Neuropsychopharmacology (1998) 1.09
Cognitive function, cardiovascular reactivity, and behavior in boys at high risk for alcoholism. J Abnorm Psychol (1995) 1.08
Validation of a system of classifying female substance abusers on the basis of personality and motivational risk factors for substance abuse. Psychol Addict Behav (2000) 1.07
Mood response to acute tryptophan depletion in healthy volunteers: sex differences and temporal stability. Neuropsychopharmacology (1996) 1.07
The cold pressor test in children: methodological aspects and the analgesic effect of intraoral sucrose. Pain (1994) 1.07
Effects of intra-oral sucrose on crying, mouthing and hand-mouth contact in newborn and six-week-old infants. Dev Med Child Neurol (1994) 1.07
Brain Regional alpha-[11C]methyl-L-tryptophan trapping in impulsive subjects with borderline personality disorder. Am J Psychiatry (2001) 1.06
Development of a scleroderma-like illness during therapy with L-5-hydroxytryptophan and carbidopa. N Engl J Med (1980) 1.05
Antidepressant action of tryptophan. Lancet (1974) 1.05
Study of the brain serotonergic system with labeled alpha-methyl-L-tryptophan. J Neurochem (2001) 1.04
Effect of tryptophan administration on tryptophan, 5-hydroxyindoleacetic acid and indoleacetic acid in human lumbar and cisternal cerebrospinal fluid. J Neurol Neurosurg Psychiatry (1981) 1.03
Amygdala-hippocampal volume and verbal memory in first-degree relatives of schizophrenic patients. Psychiatry Res (2001) 1.03
Executive cognitive functions as mediators of alcohol-related aggression. Alcohol Alcohol (1998) 1.03
Analysis of 14 CAG repeat-containing genes in schizophrenia. Am J Med Genet (1999) 1.02
Provocation, acute alcohol intoxication, cognitive performance, and aggression. J Abnorm Psychol (1995) 1.02
Voluntary consumption of beverage alcohol by vervet monkeys: population screening, descriptive behavior and biochemical measures. Pharmacol Biochem Behav (1990) 1.01
Biphasic effects of alcohol on heart rate are influenced by alcoholic family history and rate of alcohol ingestion. Alcohol Clin Exp Res (1997) 1.01
Functional neuroanatomy of smooth pursuit and predictive saccades. Neuroreport (2000) 1.01
Effects on mood of acute phenylalanine/tyrosine depletion in healthy women. Neuropsychopharmacology (2000) 0.99
Cortical trapping of alpha-[(11)C]methyl-l-tryptophan, an index of serotonin synthesis, is lower in females than males. Neuroimage (2006) 0.99
Conditioning procedures with hyperactive children. Neurology (1967) 0.99
Cognitive dysfunction and the inherited predisposition to alcoholism. J Stud Alcohol (1992) 0.98
Biochemical aspects of tryptophan depletion in primates. Psychopharmacology (Berl) (1989) 0.98
Tryptophan catabolism by tryptophan pyrrolase in rat liver. The effect of tryptophan loads and changes in tryptophan pyrrolase activity. J Biol Chem (1975) 0.98
The origin of indoleacetic acid and indolepropionic acid in rat and human cerebrospinal fluid. J Neurochem (1980) 0.97
Cognitive and neuropsychological characteristics of physically aggressive boys. J Abnorm Psychol (1995) 0.97
Liver and brain tryptophan metabolism following hydrocortisone administration to rats and gerbils. Br J Pharmacol (1975) 0.97
An amino acid mixture deficient in phenylalanine and tyrosine reduces cerebrospinal fluid catecholamine metabolites and alcohol consumption in vervet monkeys. Psychopharmacology (Berl) (1998) 0.97
Effects of alcohol on psychophysiological hyperreactivity to nonaversive and aversive stimuli in men at high risk for alcoholism. J Abnorm Psychol (1990) 0.97
Altered dopamine transporter densities in alcohol-preferring vervet monkeys. Neuroreport (1996) 0.96
Importance of tryptophan pyrrolase and aromatic amino acid decarboxylase in the catabolism of tryptophan. Biochem Pharmacol (1978) 0.96
Effect of folic acid and vitamin B12 deficiencies on 5-hydroxyindoleacetic acid in human cerebrospinal fluid. Ann Neurol (1982) 0.95
The metabolism of a tryptophan load in rat brain and liver. The influence of hydrocortisone and allopurinol. Biochem Pharmacol (1976) 0.95
The effects of alcohol intoxication on aggressive responses in men and women. Alcohol Alcohol (2000) 0.95
Ethanol-induced change in cardiac and endogenous opiate function and risk for alcoholism. Alcohol Clin Exp Res (1996) 0.94
The lifetime prevalence of psychopathology in men with multigenerational family histories of alcoholism. J Nerv Ment Dis (1990) 0.94
Paternal alcoholism, paternal absence and the development of problem behaviors in boys from age six to twelve years. J Stud Alcohol (1998) 0.94
Association between the methylenetetrahydrofolate reductase 677C-->T missense mutation and schizophrenia. Mol Psychiatry (2000) 0.93
Cognitive functioning and the inhibition of alcohol-induced aggression. J Stud Alcohol (1998) 0.93
Men at high risk for alcoholism: the effect of alcohol on cardiovascular response to unavoidable shock. J Abnorm Psychol (1987) 0.93
L-Tryptophan: Biochemical, nutritional and pharmacological aspects. Amino Acids (1996) 0.93
The stress-alexithymia hypothesis: theorectical and empirical considerations. Psychother Psychosom (1985) 0.92
Statistical mapping analysis of serotonin synthesis images generated in healthy volunteers using positron-emission tomography and alpha-[11C]methyl-L-tryptophan. J Psychiatry Neurosci (2000) 0.92
Executive functions and physical aggression after controlling for attention deficit hyperactivity disorder, general memory, and IQ. J Child Psychol Psychiatry (1999) 0.92