Published in Br J Pharmacol on November 01, 1999
Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation. J Clin Invest (2007) 3.22
Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system. J Clin Invest (2006) 1.69
Vascular natriuretic peptide receptor-linked particulate guanylate cyclases are modulated by nitric oxide-cyclic GMP signalling. Br J Pharmacol (2003) 1.02
Soluble guanylate cyclase: an old therapeutic target re-visited. Br J Pharmacol (2002) 0.97
Lack of critical involvement of endothelial nitric oxide synthase in vascular nitrate tolerance in mice. Br J Pharmacol (2002) 0.93
Mechanisms of activity-dependent plasticity in cellular nitric oxide-cGMP signaling. J Biol Chem (2009) 0.91
Reciprocal regulation of human soluble and particulate guanylate cyclases in vivo. Br J Pharmacol (2006) 0.85
Resistance to endotoxic shock in mice lacking natriuretic peptide receptor-A. Br J Pharmacol (2010) 0.84
Hypoxia induces downregulation of soluble guanylyl cyclase β1 by miR-34c-5p. J Cell Sci (2012) 0.82
Effect of oral organic nitrates on expression and activity of vascular soluble guanylyl cyclase. Br J Pharmacol (2008) 0.80
Effect of 1-week treatment with erythropoietin on the vascular endothelial function in anaesthetized rabbits. Br J Pharmacol (2001) 0.79
Procyanidin C1 causes vasorelaxation through activation of the endothelial NO/cGMP pathway in thoracic aortic rings. J Med Food (2014) 0.78
G proteins Gαi1/3 are critical targets for Bordetella pertussis toxin-induced vasoactive amine sensitization. Infect Immun (2013) 0.78
Preservation of nitric oxide-induced relaxation of porcine coronary artery: roles of the dimers of soluble guanylyl cyclase, phosphodiesterase type 5, and cGMP-dependent protein kinase. Pflugers Arch (2014) 0.75
Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol (1990) 8.85
Nitric oxide synthases in mammals. Biochem J (1994) 6.50
Cyclic GMP synthesis and function. Pharmacol Rev (1987) 4.89
Presynaptic regulation of the release of catecholamines. Pharmacol Rev (1980) 4.20
Caution with use of inhaled nitric oxide. Lancet (1996) 3.87
Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo. Proc Natl Acad Sci U S A (1991) 3.22
Soluble guanylate cyclase: the forgotten sibling. Trends Pharmacol Sci (1997) 1.68
Effect of YC-1, an NO-independent, superoxide-sensitive stimulator of soluble guanylyl cyclase, on smooth muscle responsiveness to nitrovasodilators. Br J Pharmacol (1997) 1.48
Mechanism of YC-1-induced activation of soluble guanylyl cyclase. Mol Pharmacol (1998) 1.46
Nitric oxide decreases stability of mRNAs encoding soluble guanylate cyclase subunits in rat pulmonary artery smooth muscle cells. J Clin Invest (1997) 1.28
Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors. Am J Physiol (1994) 1.14
Effects of NG-nitro-L-arginine and L-arginine on regional cerebral blood flow in the cat. J Physiol (1992) 1.07
Smooth muscle cell expression of type I cyclic GMP-dependent protein kinase is suppressed by continuous exposure to nitrovasodilators, theophylline, cyclic GMP, and cyclic AMP. J Clin Invest (1997) 1.05
Role of endogenous nitric oxide in septic shock. New Horiz (1993) 1.04
Downregulation of nitrovasodilator-induced cyclic GMP accumulation in cells exposed to endotoxin or interleukin-1 beta. Br J Pharmacol (1996) 1.04
Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group. Role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide. J Biol Chem (1994) 1.01
Mechanisms of tolerance to sodium nitroprusside in rat cultured aortic smooth muscle cells. Br J Pharmacol (1996) 1.00
Evidence that additional mechanisms to cyclic GMP mediate the decrease in intracellular calcium and relaxation of rabbit aortic smooth muscle to nitric oxide. Br J Pharmacol (1998) 0.96
Mechanism of vascular relaxation induced by the nitric oxide (NO)/nucleophile complexes, a new class of NO-based vasodilators. J Cardiovasc Pharmacol (1993) 0.93
Vascular reactivity in mesenteric resistance arteries following chronic nitric oxide synthase inhibition in Wistar rats. Br J Pharmacol (1996) 0.92
The cGMP phosphodiesterase inhibitor zaprinast enhances the effect of nitric oxide. Am J Respir Crit Care Med (1995) 0.91
Effect of cGMP inhibitors on the actions of nitrodilators in rat aorta. Clin Exp Pharmacol Physiol (1998) 0.90
Role of nitric oxide and guanosine 3',5'-cyclic monophosphate in mediating nonadrenergic, noncholinergic relaxation in guinea-pig pulmonary arteries. Br J Pharmacol (1992) 0.86
Phosphodiesterase isozyme inhibition and the potentiation by zaprinast of endothelium-derived relaxing factor and guanylate cyclase stimulating agents in vascular smooth muscle. J Pharmacol Exp Ther (1989) 0.83
Sustained nitric oxide exposure decreases soluble guanylate cyclase mRNA and enzyme activity in pulmonary artery smooth muscle. J Surg Res (1998) 0.83
Cyclic GMP regulates cromakalim-induced relaxation in the rat aortic smooth muscle: role of cyclic GMP in K(ATP)-channels. Life Sci (1999) 0.81
Studies on vascular smooth muscle tolerance to different cGMP-mediated vasodilators and cross-tolerance to glyceryl trinitrate. Pharmacol Toxicol (1988) 0.80
Hyporesponsiveness to inhaled nitric oxide in isolated, perfused lungs from endotoxin-challenged rats. Am J Physiol (1996) 0.80
The beta-adrenergic receptor-adenylate cyclase complex as a target for therapeutic intervention in heart failure. Eur Heart J (1989) 0.79
Advances on beta-adrenergic receptors. Molecular structure and functional regulation. Am J Hypertens (1989) 0.79
L-NG-monomethyl arginine and L-NG-nitro arginine inhibit non-adrenergic, non-cholinergic relaxation of the mouse anococcygeus muscle. Br J Pharmacol (1990) 2.84
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
Acute systemic inflammation impairs endothelium-dependent dilatation in humans. Circulation (2000) 2.27
L-NG-nitro arginine inhibits non-adrenergic, non-cholinergic relaxations of guinea-pig isolated tracheal smooth muscle. Br J Pharmacol (1990) 2.12
Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: relevance to endothelial dysfunction in hypercholesterolemia. Circ Res (2001) 2.02
Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases. Biochem J (1999) 2.00
Biphasic regulation of NF-kappa B activity underlies the pro- and anti-inflammatory actions of nitric oxide. J Immunol (2001) 1.58
Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br J Pharmacol (1993) 1.56
Conversion of nitroxyl (HNO) to nitric oxide (NO) in biological systems: the role of physiological oxidants and relevance to the biological activity of HNO. Biochem Biophys Res Commun (1993) 1.44
An investigation of some S-nitrosothiols, and of hydroxy-arginine, on the mouse anococcygeus. Br J Pharmacol (1992) 1.33
Protection against lipopolysaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice. FASEB J (2003) 1.18
Biochemical characterization of S-nitrosohemoglobin. Mechanisms underlying synthesis, no release, and biological activity. J Biol Chem (1999) 1.09
Induction of NG-monomethyl-L-arginine uptake: a mechanism for differential inhibition of NO synthases? Am J Physiol (1995) 1.07
Novel aspects of endothelium-dependent regulation of vascular tone. Kidney Int (2006) 1.05
Negative modulation of nitric oxide synthase by nitric oxide and nitroso compounds. Adv Pharmacol (1995) 0.99
Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice. Nitric Oxide (2009) 0.94
KATP channel activation induces ischemic preconditioning of the endothelium in humans in vivo. Circulation (2004) 0.94
The influence of L-NG-nitro-arginine on field stimulation induced contractions and acetylcholine release in guinea pig isolated tracheal smooth muscle. Biochem Biophys Res Commun (1991) 0.94
Synthesis and biological evaluation of novel pyrazoles and indazoles as activators of the nitric oxide receptor, soluble guanylate cyclase. J Med Chem (2001) 0.92
Reciprocal regulation of cGMP-mediated vasorelaxation by soluble and particulate guanylate cyclases. Am J Physiol Heart Circ Physiol (2001) 0.90
Dose- and time-dependency of the dilator effects of the endothelin antagonist, BQ-123, in the human forearm. Br J Clin Pharmacol (1997) 0.88
Cyclic nucleotide content of the rat anococcygeus during relaxations induced by drugs or by non-adrenergic, non-cholinergic field stimulation. J Pharm Pharmacol (1991) 0.88
Changes in endothelium-dependent vasodilatation and alpha-adrenergic responses in resistance vessels during the menstrual cycle in healthy women. J Clin Endocrinol Metab (2001) 0.87
Dialysis improves endothelial function in humans. Nephrol Dial Transplant (2001) 0.87
Reciprocal regulation of human soluble and particulate guanylate cyclases in vivo. Br J Pharmacol (2006) 0.85
C-type natriuretic peptide: new candidate for endothelium-derived hyperpolarising factor. Int J Biochem Cell Biol (2004) 0.84
The influence of L-NG-nitro-arginine on sympathetic nerve induced contraction and noradrenaline release in the rat isolated anococcygeus muscle. J Auton Pharmacol (1993) 0.84
Acute administration of L-arginine does not improve arterial endothelial function in chronic renal failure. Kidney Int (2001) 0.83
Systemic vascular adaptation to increases in blood volume: the role of the blood-vessel wall. Nephrol Dial Transplant (1996) 0.79
Comparison of sevoflurane and total intravenous anaesthesia for daycase urological surgery. Anaesthesia (1999) 0.78
Nitric oxide regulates endothelium-dependent vasodilator responses in rabbit hindquarters vascular bed in vivo. Am J Physiol (1996) 0.78
Determinants of the response of human blood vessels to nitric oxide donors in vivo. J Pharmacol Exp Ther (1999) 0.77
Effect of diadenosine phosphates on human umbilical vessels: novel platelet-derived vasoconstrictors. Br J Clin Pharmacol (1995) 0.77
Intrinsic defence capacity and therapeutic potential of natriuretic peptides in pulmonary hypertension associated with lung fibrosis. Br J Pharmacol (2014) 0.75
Combined morphine-bupivacaine caudals for reconstructive penile surgery in children: systemic absorption of morphine and postoperative analgesia. Anaesth Intensive Care (1991) 0.75
Effects of sodium intake on the pressor and renal responses to nitric oxide synthesis inhibition in normotensive individuals with different sodium sensitivity. J Hypertens (2000) 0.75