Published in J Med Chem on November 04, 1999
3-(2-Amino-ethyl)-2-(4-chloro-anilino)-quinazolin-4(3H)-one methanol 0.75-solvate. Acta Crystallogr Sect E Struct Rep Online (2008) 1.76
3-(2-Hydroxy-ethyl)-2-(p-tolyl-amino)-quinazolin-4(3H)-one. Acta Crystallogr Sect E Struct Rep Online (2008) 0.85
2-Anilino-3-(2-hy-droxy-phen-yl)quinazolin-4(3H)-one methanol monosolvate. Acta Crystallogr Sect E Struct Rep Online (2010) 0.85
In silico molecular docking and in vitro antidiabetic studies of dihydropyrimido[4,5-a]acridin-2-amines. Biomed Res Int (2014) 0.76
2-[2-(2-Anilino-4-oxo-3,4-dihydro-quinazolin-3-yl)phen-oxy]-3-phenyl-quinazolin-4(3H)-one methanol hemisolvate. Acta Crystallogr Sect E Struct Rep Online (2010) 0.75
3-(2-Amino-eth-yl)-2-[4-(trifluoro-meth-oxy)anilino]quinazolin-4(3H)-one. Acta Crystallogr Sect E Struct Rep Online (2010) 0.75
3,3'-Bis(4-chloro-phen-yl)-2,2'-(m-phenyl-enedi-oxy)diquinazolin-4(3H)-one. Acta Crystallogr Sect E Struct Rep Online (2008) 0.75
N-(2,5-Dimeth-oxy-phen-yl)-6-nitro-quinazolin-4-amine. Acta Crystallogr Sect E Struct Rep Online (2012) 0.75
2-(1,3-Benzodioxol-5-yl)-3-phenyl-quinazolin-4(3H)-one. Acta Crystallogr Sect E Struct Rep Online (2013) 0.75
Synthesis of quinazolines from N-(2-nitrophenylsulfonyl)iminodiacetate and alpha-(2-nitrophenylsulfonyl)amino ketones via 2H-indazole 1-oxides. J Org Chem (2010) 0.75
Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR. Medchemcomm (2017) 0.75
A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein. Science (1989) 9.68
Patterns of variant polyadenylation signal usage in human genes. Genome Res (2000) 6.09
RNAMotif, an RNA secondary structure definition and search algorithm. Nucleic Acids Res (2001) 4.96
Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression. J Biol Chem (1993) 3.70
Poly (rC) binding protein 2 forms a ternary complex with the 5'-terminal sequences of poliovirus RNA and the viral 3CD proteinase. RNA (1997) 3.47
Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant. Mol Cell Biol (1994) 3.27
Predicting oligonucleotide affinity to nucleic acid targets. RNA (1999) 2.67
De novo initiation of viral RNA-dependent RNA synthesis. Virology (2001) 2.35
Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets. J Med Chem (1993) 2.34
Prediction of rho-independent transcriptional terminators in Escherichia coli. Nucleic Acids Res (2001) 2.30
Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity. Nucleic Acids Res (1995) 2.30
Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides. Nat Biotechnol (1999) 2.27
Implication of RNA structure on antisense oligonucleotide hybridization kinetics. Biochemistry (1992) 2.17
Conformation of an RNA pseudoknot. J Mol Biol (1990) 2.02
Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides. J Biol Chem (1992) 1.99
A pseudoknotted RNA oligonucleotide. Nature (1988) 1.98
Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion. Proc Natl Acad Sci U S A (1994) 1.94
Chemical synthesis and expression of a cassette adapted ubiquitin gene. J Biol Chem (1987) 1.84
Yeast metallothionein and applications in biotechnology. Microbiol Rev (1987) 1.82
Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection. Nucleic Acids Res (1991) 1.80
Solution conformation of an RNA hairpin loop. Biochemistry (1990) 1.74
Oligodeoxynucleotides containing 2'-O-modified adenosine: synthesis and effects on stability of DNA:RNA duplexes. Biochemistry (1993) 1.71
Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA. Nat Struct Biol (1999) 1.65
Evidence for a methylation-blocking factor (mbf) locus involved in pap pilus expression and phase variation in Escherichia coli. J Bacteriol (1991) 1.64
Effects of RNA secondary structure on cellular antisense activity. Nucleic Acids Res (2000) 1.60
Iron uptake from ferrichrome A and iron citrate in Ustilago sphaerogena. J Bacteriol (1983) 1.60
Pseudo--half-knot formation with RNA. Science (1992) 1.58
Cost-effectiveness of the diagnostic evaluation of vertigo. Laryngoscope (1999) 1.56
Murine B-cell subpopulations responsive to T-dependent and T-independent antigens. J Exp Med (1976) 1.49
Variation in reference cells for DNA analysis of paraffin-embedded tissue. Am J Clin Pathol (1992) 1.40
Nursing orientation: a continuous quality improvement story. Clin Nurse Spec (1996) 1.40
Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element. Nucleic Acids Res (1991) 1.37
Biochemical and antitumor activity of tiazofurin and its selenium analog (2-beta-D-ribofuranosyl-4-selenazolecarboxamide). Biochem Pharmacol (1985) 1.34
Siderophore iron transport followed by electron paramagnetic resonance spectroscopy. J Biol Chem (1982) 1.33
Potent and specific inhibition of HIV envelope-mediated cell fusion and virus binding by G quartet-forming oligonucleotide (ISIS 5320). AIDS Res Hum Retroviruses (1994) 1.33
Ubiquitin fusion augments the yield of cloned gene products in Escherichia coli. Proc Natl Acad Sci U S A (1989) 1.30
Biochemical and NMR studies of RNA conformation with an emphasis on RNA pseudoknots. Methods Enzymol (1995) 1.30
Evidence that bovine conglutinin reacts with an early product of C3b degradation, and an improved conglutination assay. J Immunol (1978) 1.29
Yeast metallothionein function in metal ion detoxification. J Biol Chem (1986) 1.28
In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells. Nucleic Acids Res (1997) 1.28
Effect of selenazofurin on influenza A and B virus infections of mice. Antiviral Res (1986) 1.25
Role of two siderophores in Ustilago sphaerogena. Regulation of biosynthesis and uptake mechanisms. Biochim Biophys Acta (1982) 1.23
Identification of sequence motifs in oligonucleotides whose presence is correlated with antisense activity. Nucleic Acids Res (2000) 1.22
Interaction of poly(rC) binding protein 2 with the 5' noncoding region of hepatitis A virus RNA and its effects on translation. J Virol (1998) 1.22
Recognition and transport of ferric enterobactin in Escherichia coli. J Bacteriol (1986) 1.21
Development of a quantitative real-time polymerase chain reaction assay to target a novel group of ammonia-producing bacteria found in poultry litter. Poult Sci (2008) 1.18
Ubiquitin-metallothionein fusion protein expression in yeast. A genetic approach for analysis of ubiquitin functions. J Biol Chem (1988) 1.15
Impaired glucocorticoid synthesis in premature infants developing chronic lung disease. Pediatr Res (2001) 1.14
RNA folding: pseudoknots, loops and bulges. Bioessays (1989) 1.08
Investigation of some properties of oligodeoxynucleotides containing 4'-thio-2'-deoxynucleotides: duplex hybridization and nuclease sensitivity. Nucleic Acids Res (1996) 1.07
Gene synthesis, expression, and processing of human ubiquitin carboxyl extension proteins. J Biol Chem (1989) 1.07
Determinants of aminoglycoside-binding specificity for rRNA by using mass spectrometry. Proc Natl Acad Sci U S A (1999) 1.07
Enhancement of ribosomal frameshifting by oligonucleotides targeted to the HIV gag-pol region. Nucleic Acids Res (1992) 1.06
Culturability as an indicator of succession in microbial communities. Microb Ecol (2001) 1.05
Antisense oligodeoxynucleotides: synthesis, biophysical and biological evaluation of oligodeoxynucleotides containing modified pyrimidines. Nucleic Acids Res (1993) 1.03
DNA sequences of three papA genes from uropathogenic Escherichia coli strains: evidence of structural and serological conservation. Infect Immun (1991) 1.03
Rational screening of oligonucleotide combinatorial libraries for drug discovery. Nucleic Acids Res (1993) 1.03
Escherichia coli iron enterobactin uptake monitored by Mössbauer spectroscopy. J Bacteriol (1986) 1.03
Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR. J Comput Aided Mol Des (2000) 1.02
Synthesis and antiviral/antitumor activities of certain 3-deazaguanine nucleosides and nucleotides. J Med Chem (1984) 1.01
Tritium labeling of antisense oligonucleotides by exchange with tritiated water. Nucleic Acids Res (1993) 0.98
Deconvolution of combinatorial libraries for drug discovery: experimental comparison of pooling strategies. J Med Chem (1996) 0.98
Evaluation of pyrimidine PNA binding to ssDNA targets from nonequilibrium melting experiments. Nucleic Acids Res (1997) 0.97
Fully modified 2' MOE oligonucleotides redirect polyadenylation. Nucleic Acids Res (2001) 0.96
Evaluation of the anti-herpesvirus drug combinations: virazole plus arabinofuranosylhypoxanthine and virazole plus arabinofuranosyladenine. Antiviral Res (1982) 0.95
Synthesis and antitumor activity of fluorine-substituted 4-amino-2(1H)-pyridinones and their nucleosides. 3-Deazacytosines. J Med Chem (1987) 0.94
Synthesis of 3-deazaguanine, 3-deazaguanosine, and 3-deazaguanylic acid by a novel ring closure of imidazole precursors. J Am Chem Soc (1976) 0.94
Inhospital family practice--a one year summary. J Fam Pract (1979) 0.94
2'-O-aminopropyl ribonucleotides: a zwitterionic modification that enhances the exonuclease resistance and biological activity of antisense oligonucleotides. J Med Chem (1996) 0.94
Synthetic oligonucleotides as therapeutics: the coming of age. Biotechnol Annu Rev (2000) 0.94
Trends in educational placement and cost-benefit considerations in children with cochlear implants. Arch Otolaryngol Head Neck Surg (1999) 0.93
Structural origins of the exonuclease resistance of a zwitterionic RNA. Proc Natl Acad Sci U S A (1999) 0.93
Expression and accurate processing of yeast penta-ubiquitin in Escherichia coli. J Biol Chem (1987) 0.93
Identification of an Escherichia coli genetic locus involved in thermoregulation of the pap operon. J Bacteriol (1990) 0.93
Synthesis and antiviral and enzymatic studies of certain 3-deazaguanines and their imidazolecarboxamide precursors. J Med Chem (1978) 0.92
A prospective study of the cost-utility of the multichannel cochlear implant. Arch Otolaryngol Head Neck Surg (1999) 0.92
Complement-dependent and -independent pathways of T cell-B cell cooperation. J Immunol (1977) 0.88
The transport of Mycobacterium avium subsp. paratuberculosis through saturated aquifer materials. Lett Appl Microbiol (2009) 0.88
Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides. J Org Chem (2001) 0.88
Simultaneous determination of hydrazine, methylhydrazine, and 1,1-dimethylhydrazine in air by derivatization/gas chromatography. Anal Chem (1984) 0.87
Lymphoblasts with both T and B markers in childhood leukemia and lymphoma. Blood (1977) 0.87
Total synthesis of the cyathane diterpenoid (+/-)-sarcodonin G. Org Lett (2000) 0.87
Increased turnover of intestinal mucosal cells of germfree mice induced by cholic acid. Proc Soc Exp Biol Med (1971) 0.87
Activity of selenazofurin against influenza A and B viruses in vitro. Antimicrob Agents Chemother (1985) 0.87
Multiple (alpha-NH-ubiquitin)protein endoproteases in cells. J Biol Chem (1989) 0.86
Inhibition of NF-kappa B specific transcriptional activation by PNA strand invasion. Nucleic Acids Res (1995) 0.86
Inhibition of human immunodeficiency virus type 1 infection in SCID-hu Thy/Liv mice by the G-quartet-forming oligonucleotide, ISIS 5320. Antimicrob Agents Chemother (1998) 0.85
Activation of B cell subsets by T-dependent and T-independent antigens. Adv Exp Med Biol (1978) 0.85
Anti-CD31 delays platelet adhesion/aggregation at sites of endothelial injury in mouse cerebral arterioles. Am J Pathol (1994) 0.85
The effect of alum addition on microbial communities in poultry litter. Poult Sci (2008) 0.85