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N Hay

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway. Genes Dev 1998 6.89
2 Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene. Genes Dev 2001 6.15
3 The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev 1997 5.58
4 Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev 2001 5.12
5 The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Exp Cell Res 1999 4.66
6 Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1. Genes Dev 1994 3.70
7 Attenuation in the control of SV40 gene expression. Cell 1982 3.32
8 Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt. Oncogene 2006 3.17
9 Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3. Proc Natl Acad Sci U S A 2001 3.02
10 Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria. Mol Cell Biol 1999 2.93
11 Neoplastic transformation by the human gene N-myc. Mol Cell Biol 1987 2.17
12 Progression of LNCaP prostate tumor cells during androgen deprivation: hormone-independent growth, repression of proliferation by androgen, and role for p27Kip1 in androgen-induced cell cycle arrest. Mol Endocrinol 1998 2.06
13 Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2. Mol Cell Biol 1993 1.79
14 Sequence-specific transcriptional activation by Myc and repression by Max. Mol Cell Biol 1993 1.77
15 c-Myc induces the expression and activity of ornithine decarboxylase. Cell Growth Differ 1993 1.60
16 Increased androgen receptor activity and altered c-myc expression in prostate cancer cells after long-term androgen deprivation. Cancer Res 1994 1.52
17 Attenuation of late simian virus 40 mRNA synthesis is enhanced by the agnoprotein and is temporally regulated in isolated nuclear systems. Mol Cell Biol 1985 1.43
18 Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line. Mol Cell Biol 1998 1.41
19 The role of RNA molecules in transduction of the proto-oncogene c-fps. Cell 1986 1.39
20 Transcription enhancer factor 1 interacts with a basic helix-loop-helix zipper protein, Max, for positive regulation of cardiac alpha-myosin heavy-chain gene expression. Mol Cell Biol 1997 1.37
21 Attenuation in SV40 as a mechanism of transcription-termination by RNA polymerase B. Nucleic Acids Res 1984 1.35
22 Repeated CT elements bound by zinc finger proteins control the absolute and relative activities of the two principal human c-myc promoters. Mol Cell Biol 1993 1.29
23 Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB. J Neurosci 1999 1.24
24 Attenuation may regulate gene expression in animal viruses and cells. CRC Crit Rev Biochem 1985 1.21
25 Site of premature termination of late transcription of simian virus 40 DNA: enhancement by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole. Proc Natl Acad Sci U S A 1982 1.20
26 Induction of cell cycle progression and acceleration of apoptosis are two separable functions of c-Myc: transrepression correlates with acceleration of apoptosis. Mol Cell Biol 2000 1.18
27 Activation of NF-kappa B by bradykinin through a Galpha(q)- and Gbeta gamma-dependent pathway that involves phosphoinositide 3-kinase and Akt. J Biol Chem 2000 1.17
28 p21 Disrupts the interaction between cdk2 and the E2F-p130 complex. Mol Cell Biol 1996 1.16
29 Transcription termination in animal viruses and cells. Gene 1988 1.06
30 A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function. Oncogene 2001 1.05
31 In vitro premature termination in SV40 late transcription. EMBO J 1983 1.02
32 A kinetic analysis of the nucleotide-induced allosteric transitions of GroEL. J Mol Biol 1999 1.02
33 Deletion of a nonconserved region of Bcl-2 confers a novel gain of function: suppression of apoptosis with concomitant cell proliferation. Cancer Res 1996 0.99
34 Expression, regulation, and chromosomal localization of the Max gene. Proc Natl Acad Sci U S A 1992 0.98
35 Role of the intramolecular phase in high-harmonic generation. Phys Rev Lett 2002 0.96
36 The effect Akt2 deletion on tumor development in Pten(+/-) mice. Oncogene 2011 0.96
37 Control of late simian virus 40 transcription by the attenuation mechanism and transcriptionally active ternary complexes are associated with the nuclear matrix. J Mol Biol 1984 0.96
38 Attenuation and modulation of mRNA secondary structure in a feedback control system regulating SV40 gene expression. Mol Biol Rep 1983 0.94
39 Retracted Blockage of the early events of mitogenic signaling by interferon-gamma in macrophages in response to colony-stimulating factor-1. Blood 1995 0.88
40 Apoptosis induced by differentiation or serum deprivation in an immortalized central nervous system neuronal cell line. J Neurochem 1996 0.86
41 Structural analysis of the mouse prosaposin (SGP-1) gene reveals the presence of an exon that is alternatively spliced in transcribed mRNAs. Mol Reprod Dev 1997 0.83
42 SV40 deletion mutant (d1861) with agnoprotein shortened by four amino acids. Virology 1984 0.82
43 Distribution of mouse sulfated glycoprotein-1 (prosaposin) in the testis and other tissues. J Androl 1998 0.81
44 Common dental features and craniofacial development of three siblings with Ter Haar syndrome. Eur Arch Paediatr Dent 2013 0.81
45 Intrinsic fluorescence studies of the chaperonin GroEL containing single Tyr --> Trp replacements reveal ligand-induced conformational changes. J Biol Chem 1996 0.80
46 Palate lengthening by buccinator myomucosal flaps for velopharyngeal insufficiency. Cleft Palate Craniofac J 2012 0.80
47 Requirement of E. coli DNA synthesis functions for the lytic replication of bacteriophage P1. Virology 1983 0.79
48 Prolonged vitamin D intoxication: presentation, pathogenesis and progress. Intern Med J 2013 0.79
49 Myc drives apoptosis in PC12 cells in the absence of Max. Oncogene 2001 0.76
50 Histological changes induced by CO2 laser microprobe specially designed for root canal sterilization: in vivo study. J Clin Laser Med Surg 1998 0.76
51 Trans-cranial placement of an amplatzer device to control intractable cardiac failure in an infant with a vein of galen anomaly. A case report. Interv Neuroradiol 2010 0.75
52 Nephropathy in diabetes. N Z Med J 1997 0.75
53 Efficient and accurate in vitro processing of simian virus 40-associated small RNA. J Virol 1986 0.75
54 Steroid confusion: another cautionary tale. N Z Med J 1999 0.75
55 Adhesive pre-coated brackets, a comparative clinical study. Br J Orthod 1996 0.75
56 Control of laser heating in clusters through variation in temporal pulse shape. Opt Express 2003 0.75
57 Retraction. Blockage of the early events of mitogenic signaling by interferon-gamma in macrophages in response to colony-stimulating factor-1. Blood 1996 0.75
58 Analysis of chlorthalidone in biological fluids by high-performance liquid chromatography using a rapid column cleanup procedure. Ther Drug Monit 1984 0.75
59 Characteristics of a specific radioimmunoassay for measurement of ferritin on the surface of peripheral mononuclear white blood cells in cancer patients. J Immunoassay 1984 0.75
60 Proceedings: Pseudohypoparathyroidism and pseudo-pseudohypoparathyroidism. Br J Dermatol 1974 0.75
61 Management of patients with sickle cell pain in the community. J R Coll Physicians Lond 2000 0.75
62 Studies on the ignition properties of unipolar and bipolar diathermy probes. Gastrointest Endosc 1989 0.75
63 Three years of clinical evaluation of endodontically treated teeth by 15 F CO2 laser microprobe: in vivo study. J Clin Laser Med Surg 1999 0.75
64 Students: looking out for your own. Nurs Stand 1990 0.75