Published in Nature on November 25, 1999
Cells keep a memory of their tissue origin during axolotl limb regeneration. Nature (2009) 4.49
Deep homology and the origins of evolutionary novelty. Nature (2009) 3.31
Hematopoietic, angiogenic and eye defects in Meis1 mutant animals. EMBO J (2004) 2.55
Ultraconserved elements in insect genomes: a highly conserved intronic sequence implicated in the control of homothorax mRNA splicing. Genome Res (2005) 2.02
Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning. Nature (2008) 2.01
Antagonism between retinoic acid and fibroblast growth factor signaling during limb development. Cell Rep (2013) 1.65
Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis. Genes Dev (2002) 1.57
Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax. Genes Dev (2006) 1.42
Application of synthetic photostable retinoids induces novel limb and facial phenotypes during chick embryogenesis in vivo. J Anat (2013) 1.38
Global gene expression profiles reveal significant nuclear reprogramming by the blastocyst stage after cloning. Proc Natl Acad Sci U S A (2005) 1.27
Pbx3 deficiency results in central hypoventilation. Am J Pathol (2004) 1.22
MEIS1 intronic risk haplotype associated with restless legs syndrome affects its mRNA and protein expression levels. Hum Mol Genet (2009) 1.21
Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton. Dev Biol (2007) 1.19
Transactivation function of an approximately 800-bp evolutionarily conserved sequence at the SHOX 3' region: implication for the downstream enhancer. Am J Hum Genet (2006) 1.17
Replication of restless legs syndrome loci in three European populations. J Med Genet (2009) 1.08
PBX1 nuclear export is regulated independently of PBX-MEINOX interaction by PKA phosphorylation of the PBC-B domain. EMBO J (2003) 1.07
Expression of zebrafish pax6b in pancreas is regulated by two enhancers containing highly conserved cis-elements bound by PDX1, PBX and PREP factors. BMC Dev Biol (2008) 1.06
Lateral motor column axons execute a ternary trajectory choice between limb and body tissues. Neural Dev (2007) 1.05
Nonmuscle myosin promotes cytoplasmic localization of PBX. Mol Cell Biol (2003) 1.03
Non-redundant selector and growth-promoting functions of two sister genes, buttonhead and Sp1, in Drosophila leg development. PLoS Genet (2010) 0.98
SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling. Development (2011) 0.95
Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection. Brain (2010) 0.95
PBX/extradenticle is required to re-establish axial structures and polarity during planarian regeneration. Development (2013) 0.94
Targeted resequencing and systematic in vivo functional testing identifies rare variants in MEIS1 as significant contributors to restless legs syndrome. Am J Hum Genet (2014) 0.93
Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability. Nucleic Acids Res (2005) 0.92
The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons. Neural Dev (2012) 0.90
Gene expression profiling of embryonic human neural stem cells and dopaminergic neurons from adult human substantia nigra. PLoS One (2011) 0.90
The role of meis1 in primitive and definitive hematopoiesis during zebrafish development. Haematologica (2010) 0.90
Pbx homeodomain proteins: TALEnted regulators of limb patterning and outgrowth. Dev Dyn (2011) 0.89
Identification of E74-like factor 1 (ELF1) as a transcriptional regulator of the Hox cofactor MEIS1. Exp Hematol (2010) 0.89
Alternative splicing modulates Ubx protein function in Drosophila melanogaster. Genetics (2009) 0.89
Xpbx1b and Xmeis1b play a collaborative role in hindbrain and neural crest gene expression in Xenopus embryos. Proc Natl Acad Sci U S A (2002) 0.89
MEIS2 is essential for neuroblastoma cell survival and proliferation by transcriptional control of M-phase progression. Cell Death Dis (2014) 0.88
Genome-wide association studies of sleep disorders. Chest (2011) 0.87
Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor. Front Cell Neurosci (2015) 0.87
Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation. Blood (2012) 0.87
Co-option of an anteroposterior head axis patterning system for proximodistal patterning of appendages in early bilaterian evolution. Dev Biol (2010) 0.86
Meis2 is essential for cranial and cardiac neural crest development. BMC Dev Biol (2015) 0.85
The making of differences between fins and limbs. J Anat (2012) 0.85
Specific mesenchymal/epithelial induction of olfactory receptor, vomeronasal, and gonadotropin-releasing hormone (GnRH) neurons. Dev Dyn (2010) 0.84
The Meis homeoprotein regulates the axolotl Prod 1 promoter during limb regeneration. Gene (2011) 0.83
Classic limb patterning models and the work of Dennis Summerbell. Development (2008) 0.81
Contrasting 5' and 3' evolutionary histories and frequent evolutionary convergence in Meis/hth gene structures. Genome Biol Evol (2011) 0.81
Molecular anatomy of the developing limb in the coquí frog, Eleutherodactylus coqui. Evol Dev (2012) 0.80
Bat Accelerated Regions Identify a Bat Forelimb Specific Enhancer in the HoxD Locus. PLoS Genet (2016) 0.80
Data-driven modelling of a gene regulatory network for cell fate decisions in the growing limb bud. Mol Syst Biol (2015) 0.79
Dermoskeleton morphogenesis in zebrafish fins. Dev Dyn (2010) 0.79
Differential expression of Meis2, Mab21l2 and Tbx3 during limb development associated with diversification of limb morphology in mammals. PLoS One (2014) 0.79
Hox transcription factors influence motoneuron identity through the integrated actions of both homeodomain and non-homeodomain regions. Dev Dyn (2012) 0.78
Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cells. Proc Natl Acad Sci U S A (2017) 0.77
Retinoic acid is involved in the metamorphosis of the anal fin into an intromittent organ, the gonopodium, in the green swordtail (Xiphophorus hellerii). PLoS One (2013) 0.76
Misexpression of Pknox2 in mouse limb bud mesenchyme perturbs zeugopod development and deltoid crest formation. PLoS One (2013) 0.76
Animal models of RLS phenotypes. Sleep Med (2016) 0.75
TFBSbank: a platform to dissect the big data of protein-DNA interaction in human and model species. Nucleic Acids Res (2016) 0.75
Genome-wide histone state profiling of fibroblasts from the opossum, Monodelphis domestica, identifies the first marsupial-specific imprinted gene. BMC Genomics (2014) 0.75
MEIS1, a Promising Candidate Gene, Is Not Associated with the Core Symptoms of Antipsychotic-Induced Restless Legs Syndrome in Korean Schizophrenia Patients. Psychiatry Investig (2015) 0.75
Retinoic acid-independent expression of Meis2 during autopod patterning in the developing bat and mouse limb. Evodevo (2015) 0.75
Chromosomal binding sites of the homeotic cofactor Homothorax. Mol Genet Genomics (2008) 0.75
Deep phylogenomics of a tandem-repeat galectin regulating appendicular skeletal pattern formation. BMC Evol Biol (2016) 0.75
Depletion of MEIS2 inhibits osteogenic differentiation potential of human dental stem cells. Int J Clin Exp Med (2015) 0.75
MEIS homeodomain proteins facilitate PARP1/ARTD1-mediated eviction of histone H1. J Cell Biol (2017) 0.75
Transcriptional changes in chick wing bud polarization induced by retinoic acid. Dev Dyn (2017) 0.75
Rapid diversification of homothorax expression patterns after gene duplication in spiders. BMC Evol Biol (2017) 0.75
Meis1 effects on motor phenotypes and the sensorimotor system in mice. Dis Model Mech (2017) 0.75
The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev (1996) 7.78
Minutes: mutants of drosophila autonomously affecting cell division rate. Dev Biol (1975) 5.76
The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature (1997) 4.69
Developmental compartmentalisation of the wing disk of Drosophila. Nat New Biol (1973) 4.36
Genetic organization of Drosophila bithorax complex. Nature (1985) 4.30
WNTs modulate cell fate and behavior during vertebrate development. Trends Genet (1997) 3.44
Racism and the physical and mental health status of African Americans: a thirteen year national panel study. Ethn Dis (1996) 3.34
Liver dysfunction related to hepatitis B and C in patients with inflammatory bowel disease treated with immunosuppressive therapy. Gut (2010) 2.98
The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing. Mol Cell (2000) 2.97
Visualization of gene expression in living adult Drosophila. Science (1996) 2.92
Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG. Nature (1999) 2.87
Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in beta-catenin that are modulated by the Wnt signaling pathway. J Cell Biol (1997) 2.42
Sequential functions of the bithorax complex of Drosophila. Nature (1981) 2.31
Dysgenesis of cephalic neural crest derivatives in Pax7-/- mutant mice. Development (1996) 2.31
Colinearity and functional hierarchy among genes of the homeotic complexes. Trends Genet (1994) 2.17
Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase. EMBO J (1998) 2.13
Redox signaling in macrophages. Mol Aspects Med (2001) 2.10
Detection of lipoarabinomannan as a diagnostic test for tuberculosis. J Clin Microbiol (1992) 2.09
Vertebral endplate changes are not associated with chronic low back pain among Southern European subjects: a case control study. AJNR Am J Neuroradiol (2012) 2.06
Developmental compartmentalization in the dorsal mesothoracic disc of Drosophila. Dev Biol (1976) 2.06
[Factors associated with the accumulation of abdominal fat estimated with anthropometric indexes]. Med Clin (Barc) (2000) 2.02
[Nodular subependymal heterotopia and epilepsy]. Neurologia (1995) 2.02
Control of compartment development by the engrailed gene in Drosophila. Nature (1975) 2.00
Compartments in the wing of Drosophila: a study of the engrailed gene. Dev Biol (1976) 1.96
Intermittent hypoxia enhances cancer progression in a mouse model of sleep apnoea. Eur Respir J (2012) 1.94
Role of the PI3K regulatory subunit in the control of actin organization and cell migration. J Cell Biol (2000) 1.94
The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential. EMBO J (1995) 1.93
Developmental effects of some newly induced Ultrabithorax alleles of Drosophila. J Embryol Exp Morphol (1982) 1.93
Evaluation of lipoarabinomannan for the serological diagnosis of tuberculosis. J Clin Microbiol (1990) 1.89
Development of the eye-antenna imaginal disc of Drosophila. Dev Biol (1979) 1.84
Histological course of alcoholic hepatitis. Influence of abstinence, sex and extent of hepatic damage. J Hepatol (1986) 1.84
A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families. JAMA (2001) 1.82
Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial. J Hepatol (1998) 1.76
The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism. EMBO Rep (2001) 1.76
A new Drosophila homeo box gene is expressed in mesodermal precursor cells of distinct muscles during embryogenesis. Genes Dev (1990) 1.76
LAGE-1, a new gene with tumor specificity. Int J Cancer (1998) 1.76
Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. Development (2000) 1.73
Randomized comparative study of therapeutic paracentesis with and without intravenous albumin in cirrhosis. Gastroenterology (1988) 1.73
Differential mitotic rates and patterns of growth in compartments in the Drosophila wing. Dev Biol (1981) 1.72
CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses. J Clin Invest (2001) 1.69
Intravitreal ranibizumab for choroidal neovascularization secondary to pathologic myopia: 12-month results. Eye (Lond) (2009) 1.68
Development and evaluation of a rapid, simple, sensitive, monoclonal antibody-based co-agglutination test for direct detection of Vibrio cholerae 01. FEMS Microbiol Lett (1992) 1.67
Radio imaging of the very-high-energy gamma-ray emission region in the central engine of a radio galaxy. Science (2009) 1.66
[Cerebral infarction as the initial manifestation of mediterranean spotted fever]. Med Clin (Barc) (1992) 1.65
Very-high-energy gamma rays from a distant quasar: how transparent is the universe? Science (2008) 1.65
Evolution of the nucleotide sequence of influenza virus RNA segment 7 during drift of the H3N2 subtype. Gene (1983) 1.64
Epidermal growth factor receptor overexpression correlates with a poor prognosis in completely resected non-small-cell lung cancer. Ann Oncol (2004) 1.62
Control of Drosophila adult pattern by extradenticle. Development (1995) 1.61
Restriction-modification system differences in Helicobacter pylori are a barrier to interstrain plasmid transfer. Mol Microbiol (2000) 1.60
Identification and characterization of a parasegment specific regulatory element of the abdominal-B gene of Drosophila. Cell (1986) 1.59
Mycobacterium tuberculosis (MTB)-stimulated production of nitric oxide by human alveolar macrophages and relationship of nitric oxide production to growth inhibition of MTB. Tuber Lung Dis (1997) 1.58
Beryllium presentation to CD4+ T cells underlies disease-susceptibility HLA-DP alleles in chronic beryllium disease. Proc Natl Acad Sci U S A (2000) 1.57
Pharmacological inhibition of programmed lymphocyte death. Immunol Today (1994) 1.56
Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death. Development (1995) 1.55
Cis-regulation of achaete and scute: shared enhancer-like elements drive their coexpression in proneural clusters of the imaginal discs. Genes Dev (1995) 1.55
[Intraparenchymatous hematoma simulating a transitory ischemic stroke]. Med Clin (Barc) (1995) 1.54
Assembly of vault-like particles in insect cells expressing only the major vault protein. J Biol Chem (2001) 1.54
Anti-inflammatory effects of high-dose inhaled fluticasone versus oral prednisone in asthma exacerbations. Eur Respir J (2007) 1.53
Derivation of the uncontrolled donation after circulatory determination of death protocol for New York city. Am J Transplant (2011) 1.53
Homeobox genes: their function in Drosophila segmentation and pattern formation. Cell (1994) 1.52
Engraftment syndrome after auto-SCT: analysis of diagnostic criteria and risk factors in a large series from a single center. Bone Marrow Transplant (2010) 1.52
Neoadjuvant radiation and chemotherapy in rectal cancer does not increase postoperative complications. Int J Colorectal Dis (2003) 1.52
The development of wingless, a homeotic mutation of Drosophila. Dev Biol (1977) 1.51
The developmental and molecular biology of genes that subdivide the body of Drosophila. Annu Rev Cell Dev Biol (2000) 1.51
Pain in clinical oncology: patient satisfaction with management of cancer pain. Eur J Pain (2011) 1.51
Ectopic expression of homeotic genes caused by the elimination of the Polycomb gene in Drosophila imaginal epidermis. Development (1988) 1.50
Molecular cloning and sequencing of influenza virus A/Victoria/3/75 polymerase genes: sequence evolution and prediction of possible functional domains. Virus Res (1989) 1.49
Double and triple mutant combinations of bithorax complex of Drosophila. EMBO J (1987) 1.49
Anisakis simplex allergy after eating chicken meat. J Investig Allergol Clin Immunol (2006) 1.48
Control of retinal ganglion cell axon growth: a new role for Sonic hedgehog. Development (2001) 1.47
Assertive community treatment and medication compliance in the homeless mentally ill. Am J Psychiatry (1997) 1.47
Homoeotic genes, compartments and cell determination in Drosophila. Nature (1977) 1.47
The developmental effect of overexpressing a Ubx product in Drosophila embryos is dependent on its interactions with other homeotic products. Cell (1990) 1.44
Selective expansion of T cells bearing the gamma/delta receptor and expressing an unusual repertoire in the synovial membrane of patients with rheumatoid arthritis. Arthritis Rheum (1991) 1.43
Di(1,N6-ethenoadenosine)5', 5'''-P1,P4-tetraphosphate, a fluorescent enzymatically active derivative of Ap4A. FEBS Lett (1991) 1.43
[Necrotizing infections of the soft tissues]. Enferm Infecc Microbiol Clin (1996) 1.42
Concurrent hypnogenic and reflex paroxysmal dystonia. Mov Disord (1988) 1.41
Expression and regulation of the abd-A gene of Drosophila. Development (1990) 1.41
ED management of acute congestive heart failure in renal dialysis patients. Am J Emerg Med (1993) 1.40
Apoptosis, Fas and systemic autoimmunity: the MRL-lpr/lpr model. Curr Opin Immunol (1994) 1.40
[Occupational risk of hepatitis C virus infection after accidental exposure. Catalonia Group for the Study of the Occupational Risk of HCV Infection at Hospitals]. Med Clin (Barc) (1998) 1.40
Pickled onion-induced asthma: a model of sulfite-sensitive asthma? Clin Exp Allergy (1995) 1.40
Complications of central venous catheterization in critically ill children. Pediatr Crit Care Med (2001) 1.39
The elements of the bithorax complex. Cell (1983) 1.39
[Preliminary results of DERMATEL: prospective randomized study comparing synchronous and asynchronous modalities of teledermatology]. Actas Dermosifiliogr (2006) 1.39
[Difficult to manage diabetes mellitus associated with generalized congenital lipodystrophy. Report of two cases]. An Pediatr (Barc) (2010) 1.39
[Intravesical BCG and arthritis]. Med Clin (Barc) (1993) 1.39
Theory for tailoring sonic devices: diffraction dominates over refraction. Phys Rev E Stat Nonlin Soft Matter Phys (2003) 1.39
Are cross-regulatory interactions between homoeotic genes functionally significant? Nature (1990) 1.38
[Oro-esophageal candidiasis resistant to fluconazole in patients with AIDS]. Enferm Infecc Microbiol Clin (1993) 1.38
Haemothorax in the course of chickenpox. Thorax (1986) 1.38
Brain death and evoked potentials in pediatric patients. Crit Care Med (1999) 1.38
Technical pitfalls potentially affecting diagnoses in immunohistochemistry. J Clin Pathol (2008) 1.36
The role of the NK-homeobox gene slouch (S59) in somatic muscle patterning. Development (1999) 1.35
Evidence for substrate-specific requirement of the splicing factor U2AF(35) and for its function after polypyrimidine tract recognition by U2AF(65). Mol Cell Biol (1999) 1.35
Enhanced responses to Mycobacterium tuberculosis antigens by human alveolar lymphocytes during active pulmonary tuberculosis. J Infect Dis (1998) 1.34
Programmed cell death by bcl-2-dependent and independent mechanisms in B lymphoma cells. EMBO J (1993) 1.34