The three-dimensional structures of nicotinate mononucleotide:5,6- dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella typhimurium complexed with 5,6-dimethybenzimidazole and its reaction products determined to 1.9 A resolution.

PubWeight™: 0.87‹?›

🔗 View Article (PMID 10587435)

Published in Biochemistry on December 07, 1999

Authors

C G Cheong1, J C Escalante-Semerena, I Rayment

Author Affiliations

1: Institute for Enzyme Research, Department of Biochemistry, University of Wisconsin, Madison 53705, USA.

Articles by these authors

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc Natl Acad Sci U S A (2000) 6.49

X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-. Biochemistry (1995) 4.64

Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine. Science (2002) 4.61

X-ray structure of the magnesium(II).ADP.vanadate complex of the Dictyostelium discoideum myosin motor domain to 1.9 A resolution. Biochemistry (1996) 4.32

Polyoma virus capsid structure at 22.5 A resolution. Nature (1982) 4.19

Three-dimensional structure of the Tn5 synaptic complex transposition intermediate. Science (2000) 4.00

Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle. Nat Genet (1996) 3.02

Regulation of cobalamin biosynthetic operons in Salmonella typhimurium. J Bacteriol (1987) 2.74

Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1. Nature (1993) 2.44

CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis in Salmonella typhimurium LT2. J Biol Chem (1998) 2.37

The enolase superfamily: a general strategy for enzyme-catalyzed abstraction of the alpha-protons of carboxylic acids. Biochemistry (1996) 2.15

Structure of carbamoyl phosphate synthetase: a journey of 96 A from substrate to product. Biochemistry (1997) 2.14

X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain. Biochemistry (1997) 2.08

Inside polyomavirus at 25-A resolution. Nature (1992) 2.04

Is myosin a "back door" enzyme? Biophys J (1995) 1.96

The poc locus is required for 1,2-propanediol-dependent transcription of the cobalamin biosynthetic (cob) and propanediol utilization (pdu) genes of Salmonella typhimurium. J Bacteriol (1992) 1.96

Propionate catabolism in Salmonella typhimurium LT2: two divergently transcribed units comprise the prp locus at 8.5 centisomes, prpR encodes a member of the sigma-54 family of activators, and the prpBCDE genes constitute an operon. J Bacteriol (1997) 1.94

Tetrahydromethanopterin, a carbon carrier in methanogenesis. J Biol Chem (1984) 1.94

Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase. Biochemistry (1994) 1.90

Acetyl-coenzyme A synthetase (AMP forming). Cell Mol Life Sci (2004) 1.88

Active site comparisons highlight structural similarities between myosin and other P-loop proteins. Biophys J (1996) 1.80

Structure of southern bean mosaic virus at 2.8 A resolution. Nature (1980) 1.78

Conservation within the myosin motor domain: implications for structure and function. Structure (1996) 1.73

Salmonella typhimurium LT2 catabolizes propionate via the 2-methylcitric acid cycle. J Bacteriol (1999) 1.72

Construction and use of new cloning vectors for the rapid isolation of recombinant proteins from Escherichia coli. Plasmid (2008) 1.71

X-ray structure determination of telokin, the C-terminal domain of myosin light chain kinase, at 2.8 A resolution. J Mol Biol (1992) 1.69

Purification and initial characterization of the ATP:corrinoid adenosyltransferase encoded by the cobA gene of Salmonella typhimurium. J Bacteriol (1995) 1.66

Structural consequences of reductive methylation of lysine residues in hen egg white lysozyme: an X-ray analysis at 1.8-A resolution. Biochemistry (1993) 1.65

Molecular structure of an apolipoprotein determined at 2.5-A resolution. Biochemistry (1991) 1.64

X-ray structures of the apo and MgATP-bound states of Dictyostelium discoideum myosin motor domain. J Biol Chem (2000) 1.59

Structural studies of myosin:nucleotide complexes: a revised model for the molecular basis of muscle contraction. Biophys J (1995) 1.59

Structure of rabbit muscle pyruvate kinase complexed with Mn2+, K+, and pyruvate. Biochemistry (1994) 1.56

The molecular structure of insecticyanin from the tobacco hornworm Manduca sexta L. at 2.6 A resolution. EMBO J (1987) 1.56

Three-dimensional structure of Escherichia coli asparagine synthetase B: a short journey from substrate to product. Biochemistry (1999) 1.56

Three-dimensional structure of myosin subfragment-1 from electron microscopy of sectioned crystals. J Cell Biol (1991) 1.56

In vitro conversion of propionate to pyruvate by Salmonella enterica enzymes: 2-methylcitrate dehydratase (PrpD) and aconitase Enzymes catalyze the conversion of 2-methylcitrate to 2-methylisocitrate. Biochemistry (2001) 1.42

Actin-targeting natural products: structures, properties and mechanisms of action. Cell Mol Life Sci (2006) 1.41

Analysis of mutants of Salmonella typhimurium defective in the synthesis of the nucleotide loop of cobalamin. J Bacteriol (1993) 1.38

Coenzyme F420 dependence of the methylenetetrahydromethanopterin dehydrogenase of Methanobacterium thermoautotrophicum. Biochem Biophys Res Commun (1985) 1.37

Glutathione is required for maximal transcription of the cobalamin biosynthetic and 1,2-propanediol utilization (cob/pdu) regulon and for the catabolism of ethanolamine, 1,2-propanediol, and propionate in Salmonella typhimurium LT2. J Bacteriol (1995) 1.36

X-ray crystal structure of the yeast Kar3 motor domain complexed with Mg.ADP to 2.3 A resolution. Biochemistry (1998) 1.35

The cobT gene of Salmonella typhimurium encodes the NaMN: 5,6-dimethylbenzimidazole phosphoribosyltransferase responsible for the synthesis of N1-(5-phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole, an intermediate in the synthesis of the nucleotide loop of cobalamin. J Bacteriol (1994) 1.35

Three-dimensional structure of ATP:corrinoid adenosyltransferase from Salmonella typhimurium in its free state, complexed with MgATP, or complexed with hydroxycobalamin and MgATP. Biochemistry (2001) 1.34

Structure of the bis(Mg2+)-ATP-oxalate complex of the rabbit muscle pyruvate kinase at 2.1 A resolution: ATP binding over a barrel. Biochemistry (1998) 1.30

The prpE gene of Salmonella typhimurium LT2 encodes propionyl-CoA synthetase. Microbiology (1999) 1.29

An in vitro reducing system for the enzymic conversion of cobalamin to adenosylcobalamin. J Biol Chem (2001) 1.28

Component A2 of the methylcoenzyme M methylreductase system from Methanobacterium thermoautotrophicum. J Bacteriol (1985) 1.28

The three-dimensional structure of a Tn5 transposase-related protein determined to 2.9-A resolution. J Biol Chem (1999) 1.26

Three-dimensional structure of galactose-1-phosphate uridylyltransferase from Escherichia coli at 1.8 A resolution. Biochemistry (1995) 1.26

Studies of regulation of expression of the propionate (prpBCDE) operon provide insights into how Salmonella typhimurium LT2 integrates its 1,2-propanediol and propionate catabolic pathways. J Bacteriol (1998) 1.23

In vitro synthesis of the nucleotide loop of cobalamin by Salmonella typhimurium enzymes. Proc Natl Acad Sci U S A (1999) 1.23

Cloning, sequencing and overexpression of cobA which encodes ATP:corrinoid adenosyltransferase in Salmonella typhimurium. Gene (1993) 1.22

Crystallization and structure determination to 2.5-A resolution of the oxidized [2Fe-2S] ferredoxin isolated from Anabaena 7120. Biochemistry (1991) 1.22

Tn5: A molecular window on transposition. Biochem Biophys Res Commun (1999) 1.21

The structure of southern bean mosaic virus at 22.5 a resolution. Virology (1976) 1.20

The molecular structure of UDP-galactose 4-epimerase from Escherichia coli determined at 2.5 A resolution. Proteins (1992) 1.20

The cobY gene of the archaeon Halobacterium sp. strain NRC-1 is required for de novo cobamide synthesis. J Bacteriol (2003) 1.20

Purification and characterization of the bifunctional CobU enzyme of Salmonella typhimurium LT2. Evidence for a CobU-GMP intermediate. J Biol Chem (1995) 1.19

Studies of propionate toxicity in Salmonella enterica identify 2-methylcitrate as a potent inhibitor of cell growth. J Biol Chem (2001) 1.18

Three-dimensional structure of bacterial luciferase from Vibrio harveyi at 2.4 A resolution. Biochemistry (1995) 1.18

CobD, a novel enzyme with L-threonine-O-3-phosphate decarboxylase activity, is responsible for the synthesis of (R)-1-amino-2-propanol O-2-phosphate, a proposed new intermediate in cobalamin biosynthesis in Salmonella typhimurium LT2. J Biol Chem (1998) 1.18

Purification and characterization of CobT, the nicotinate-mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase enzyme from Salmonella typhimurium LT2. J Biol Chem (1997) 1.17

Packing analysis of crystalline myosin subfragment-1. Implications for the size and shape of the myosin head. J Mol Biol (1985) 1.17

X-ray structure of the magnesium(II)-pyrophosphate complex of the truncated head of Dictyostelium discoideum myosin to 2.7 A resolution. Biochemistry (1995) 1.17

DNA polymerase I function is required for the utilization of ethanolamine, 1,2-propanediol, and propionate by Salmonella typhimurium LT2. J Bacteriol (1995) 1.15

X-ray crystal structure and solution fluorescence characterization of Mg.2'(3')-O-(N-methylanthraniloyl) nucleotides bound to the Dictyostelium discoideum myosin motor domain. J Mol Biol (1997) 1.15

Ligand-induced domain movement in pyruvate kinase: structure of the enzyme from rabbit muscle with Mg2+, K+, and L-phospholactate at 2.7 A resolution. Arch Biochem Biophys (1997) 1.14

The cobC gene of Salmonella typhimurium codes for a novel phosphatase involved in the assembly of the nucleotide loop of cobalamin. J Biol Chem (1994) 1.14

Tetrahydromethanopterin-dependent methanogenesis from non-physiological C1 donors in Methanobacterium thermoautotrophicum. J Bacteriol (1985) 1.13

Identification of an alternative nucleoside triphosphate: 5'-deoxyadenosylcobinamide phosphate nucleotidyltransferase in Methanobacterium thermoautotrophicum delta H. J Bacteriol (2000) 1.11

Molecular structure of kanamycin nucleotidyltransferase determined to 3.0-A resolution. Biochemistry (1993) 1.10

A carboxylate oxygen of the substrate bridges the magnesium ions at the active site of enolase: structure of the yeast enzyme complexed with the equilibrium mixture of 2-phosphoglycerate and phosphoenolpyruvate at 1.8 A resolution. Biochemistry (1996) 1.10

Identification of 5,6-dimethylbenzimidazole as the Co alpha ligand of the cobamide synthesized by Salmonella typhimurium. Nutritional characterization of mutants defective in biosynthesis of the imidazole ring. J Biol Chem (1992) 1.10

The 1.5-A resolution crystal structure of bacterial luciferase in low salt conditions. J Biol Chem (1996) 1.10

Reduction of Cob(III)alamin to Cob(II)alamin in Salmonella enterica serovar typhimurium LT2. J Bacteriol (2000) 1.10

Metal-free southern bean mosaic virus crystals. J Biol Chem (1979) 1.09

prpR, ntrA, and ihf functions are required for expression of the prpBCDE operon, encoding enzymes that catabolize propionate in Salmonella enterica serovar typhimurium LT2. J Bacteriol (2000) 1.06

The structure of nucleotidylated histidine-166 of galactose-1-phosphate uridylyltransferase provides insight into phosphoryl group transfer. Biochemistry (1996) 1.06

Structural studies on myosin II: communication between distant protein domains. Bioessays (1997) 1.06

In vitro analysis of the interactions between the PocR regulatory protein and the promoter region of the cobalamin biosynthetic (cob) operon of Salmonella typhimurium LT2. J Bacteriol (1996) 1.05

The structure of carbamoyl phosphate synthetase determined to 2.1 A resolution. Acta Crystallogr D Biol Crystallogr (1999) 1.05

Evolution of enzymatic activity in the enolase superfamily: structure of o-succinylbenzoate synthase from Escherichia coli in complex with Mg2+ and o-succinylbenzoate. Biochemistry (2000) 1.05

Identification of a new prp locus required for propionate catabolism in Salmonella typhimurium LT2. FEMS Microbiol Lett (1996) 1.04

Molecular structure of cytochrome c2 isolated from Rhodobacter capsulatus determined at 2.5 A resolution. J Mol Biol (1991) 1.04

X-ray structures of the Dictyostelium discoideum myosin motor domain with six non-nucleotide analogs. J Biol Chem (2000) 1.03

Kinetic characterization of reductively methylated myosin subfragment 1. Biochemistry (1993) 1.03

Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli. Biochemistry (2000) 1.03

Molecular structure of the oxidized high-potential iron-sulfur protein isolated from Ectothiorhodospira vacuolata. Biochemistry (1994) 1.02

Methenyl-tetrahydromethanopterin cyclohydrolase in cell extracts of Methanobacterium. Arch Biochem Biophys (1985) 1.02

Biochemistry and molecular genetics of cobalamin biosynthesis. Prog Nucleic Acid Res Mol Biol (1997) 1.02

Chelation of serine 39 to Mg2+ latches a gate at the active site of enolase: structure of the bis(Mg2+) complex of yeast enolase and the intermediate analog phosphonoacetohydroxamate at 2.1-A resolution. Biochemistry (1994) 1.01

Channel gate! Tension, leak and disclosure. Structure (1999) 1.01

Structural and mechanistic studies of enolase. Curr Opin Struct Biol (1996) 1.01

Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase from Salmonella typhimurium determined to 2.3 A resolution,. Biochemistry (1998) 1.00

Crystallization of myosin subfragment 1. Proc Natl Acad Sci U S A (1984) 1.00

Evolution of enzymatic activities in the enolase superfamily: crystal structures of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis. Biochemistry (2001) 1.00

Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli. Biochemistry (2001) 0.98