Published in Annu Rev Cell Dev Biol on January 01, 1999
Mechanism of filopodia initiation by reorganization of a dendritic network. J Cell Biol (2003) 5.47
Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta (2006) 4.27
ADF/cofilin: a functional node in cell biology. Trends Cell Biol (2010) 3.95
Actin depolymerizing factor stabilizes an existing state of F-actin and can change the tilt of F-actin subunits. J Cell Biol (2001) 2.63
Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge. Cell (2007) 2.59
Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion. J Cell Biol (2000) 2.56
The yeast actin cytoskeleton: from cellular function to biochemical mechanism. Microbiol Mol Biol Rev (2006) 2.55
Spatial and temporal relationships between actin-filament nucleation, capping, and disassembly. Curr Biol (2007) 2.44
Cortactin branches out: roles in regulating protrusive actin dynamics. Cell Motil Cytoskeleton (2008) 2.26
Actin cytoskeletal dynamics in smooth muscle: a new paradigm for the regulation of smooth muscle contraction. Am J Physiol Cell Physiol (2008) 2.24
Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis. J Cell Biol (2009) 2.21
Tropomyosin inhibits ADF/cofilin-dependent actin filament dynamics. J Cell Biol (2002) 2.15
Phosphorylation of ADF/cofilin abolishes EGF-induced actin nucleation at the leading edge and subsequent lamellipod extension. J Cell Biol (2000) 2.10
Rapid actin monomer-insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1. J Cell Biol (2006) 2.07
Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration. J Cell Biol (2005) 2.05
Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex. Mol Biol Cell (2004) 2.05
Integrins control motile strategy through a Rho-cofilin pathway. J Cell Biol (2005) 2.04
Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts. Proc Natl Acad Sci U S A (2002) 1.97
Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks. Dev Cell (2007) 1.96
Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension. J Cell Sci (2004) 1.89
The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics. Mol Biol Cell (2002) 1.85
Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity. J Neurosci (2009) 1.83
The ADF/cofilin family: actin-remodeling proteins. Genome Biol (2002) 1.83
Structure of the actin-depolymerizing factor homology domain in complex with actin. J Cell Biol (2008) 1.75
Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension. J Cell Biol (2002) 1.72
Signal-mediated depolymerization of actin in pollen during the self-incompatibility response. Plant Cell (2002) 1.71
ADF proteins are involved in the control of flowering and regulate F-actin organization, cell expansion, and organ growth in Arabidopsis. Plant Cell (2001) 1.71
iTRAQ protein profile analysis of Arabidopsis roots reveals new aspects critical for iron homeostasis. Plant Physiol (2010) 1.71
Actin turnover-dependent fast dissociation of capping protein in the dendritic nucleation actin network: evidence of frequent filament severing. J Cell Biol (2006) 1.70
Coronin switches roles in actin disassembly depending on the nucleotide state of actin. Mol Cell (2009) 1.69
Effect of destrin mutations on the gene expression profile in vivo. Physiol Genomics (2008) 1.68
ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments. J Cell Biol (2003) 1.68
The regulation of actin organization by actin-depolymerizing factor in elongating pollen tubes. Plant Cell (2002) 1.67
BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin. J Cell Biol (2007) 1.66
Aip1 and cofilin promote rapid turnover of yeast actin patches and cables: a coordinated mechanism for severing and capping filaments. Mol Biol Cell (2006) 1.62
Rapid loss of dendritic spines after stress involves derangement of spine dynamics by corticotropin-releasing hormone. J Neurosci (2008) 1.60
Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms. Mol Cell Biol (2008) 1.57
Reactive oxygen species regulate a slingshot-cofilin activation pathway. Mol Biol Cell (2009) 1.56
Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament. J Cell Biol (2011) 1.54
The Caenorhabditis elegans unc-78 gene encodes a homologue of actin-interacting protein 1 required for organized assembly of muscle actin filaments. J Cell Biol (2001) 1.52
Specification of actin filament function and molecular composition by tropomyosin isoforms. Mol Biol Cell (2003) 1.51
Actin remodeling by ADF/cofilin is required for cargo sorting at the trans-Golgi network. J Cell Biol (2009) 1.51
The origins of phagocytosis and eukaryogenesis. Biol Direct (2009) 1.49
Dual role of SnoN in mammalian tumorigenesis. Mol Cell Biol (2006) 1.47
Regulation of actin cytoskeleton dynamics in cells. Mol Cells (2010) 1.46
Gene family encoding the major toxins of lethal Amanita mushrooms. Proc Natl Acad Sci U S A (2007) 1.45
A common cofilin activity cycle in invasive tumor cells and inflammatory cells. J Cell Sci (2009) 1.45
Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture. J Biol Chem (2010) 1.43
Actin-depolymerizing factor mediates Rac/Rop GTPase-regulated pollen tube growth. Plant Cell (2003) 1.43
Cofilin-2 phosphorylation and sequestration in myocardial aggregates: novel pathogenetic mechanisms for idiopathic dilated cardiomyopathy. J Am Coll Cardiol (2015) 1.42
LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505. Biochem J (2001) 1.40
Regulation of the pollen-specific actin-depolymerizing factor LlADF1. Plant Cell (2002) 1.40
RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability. J Cell Biol (2003) 1.39
Identification of cofilin and LIM-domain-containing protein kinase 1 as novel interaction partners of 14-3-3 zeta. Biochem J (2003) 1.39
Overlapping and distinct functions for cofilin, coronin and Aip1 in actin dynamics in vivo. J Cell Sci (2010) 1.35
LIMK1 regulates Golgi dynamics, traffic of Golgi-derived vesicles, and process extension in primary cultured neurons. Mol Biol Cell (2004) 1.35
Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation. Mol Cell Biol (2008) 1.35
Calcium-dependent protein kinase isoforms in Petunia have distinct functions in pollen tube growth, including regulating polarity. Plant Cell (2006) 1.35
ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells. J Biol Chem (2008) 1.34
Actin and pollen tube growth. Protoplasma (2001) 1.31
Monitoring actin cortex thickness in live cells. Biophys J (2013) 1.30
Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury. Kidney Int (2013) 1.27
MicroRNA-205 promotes keratinocyte migration via the lipid phosphatase SHIP2. FASEB J (2010) 1.22
Cofilin under control of β-arrestin-2 in NMDA-dependent dendritic spine plasticity, long-term depression (LTD), and learning. Proc Natl Acad Sci U S A (2012) 1.22
Pointed-end capping by tropomodulin3 negatively regulates endothelial cell motility. J Cell Biol (2003) 1.21
Class-specific interaction of profilin and ADF isovariants with actin in the regulation of plant development. Plant Cell (2007) 1.21
A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells. Mol Biol Cell (2004) 1.21
Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans. PLoS One (2010) 1.20
The pericyte: cellular regulator of microvascular blood flow. Microvasc Res (2009) 1.19
A role for cofilin and LIM kinase in Listeria-induced phagocytosis. J Cell Biol (2001) 1.19
The RNA-binding protein SUP-12 controls muscle-specific splicing of the ADF/cofilin pre-mRNA in C. elegans. J Cell Biol (2004) 1.18
ADF/Cofilin-actin rods in neurodegenerative diseases. Curr Alzheimer Res (2010) 1.18
Regulation of acetylcholine receptor clustering by ADF/cofilin-directed vesicular trafficking. Nat Neurosci (2009) 1.18
LIM kinase 1 and cofilin regulate actin filament population required for dynamin-dependent apical carrier fission from the trans-Golgi network. Mol Biol Cell (2008) 1.18
MAP1B regulates axonal development by modulating Rho-GTPase Rac1 activity. Mol Biol Cell (2010) 1.17
Emerging topics in Reelin function. Eur J Neurosci (2010) 1.17
Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly. J Cell Biol (2006) 1.17
A Plasmodium actin-depolymerizing factor that binds exclusively to actin monomers. Mol Biol Cell (2005) 1.16
The two Caenorhabditis elegans actin-depolymerizing factor/cofilin proteins differently enhance actin filament severing and depolymerization. Biochemistry (2005) 1.16
P21-activated kinase 1: convergence point in PDGF- and LPA-stimulated collagen matrix contraction by human fibroblasts. J Cell Biol (2006) 1.16
MicroRNA-related cofilin abnormality in Alzheimer's disease. PLoS One (2010) 1.15
Structural basis and evolutionary origin of actin filament capping by twinfilin. Proc Natl Acad Sci U S A (2007) 1.14
Identification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling. Proc Natl Acad Sci U S A (2000) 1.14
A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory. Mol Cell Neurosci (2009) 1.14
Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilin. EMBO J (2007) 1.14
p116Rip targets myosin phosphatase to the actin cytoskeleton and is essential for RhoA/ROCK-regulated neuritogenesis. Mol Biol Cell (2004) 1.13
Extracellular inhibitors, repellents, and semaphorin/plexin/MICAL-mediated actin filament disassembly. Cytoskeleton (Hoboken) (2011) 1.12
Mutations in the Drosophila orthologs of the F-actin capping protein alpha- and beta-subunits cause actin accumulation and subsequent retinal degeneration. Genetics (2005) 1.12
Growing actin networks form lamellipodium and lamellum by self-assembly. Biophys J (2008) 1.10
Cyclase-associated protein (CAP) acts directly on F-actin to accelerate cofilin-mediated actin severing across the range of physiological pH. J Biol Chem (2012) 1.09
Mapping the cofilin binding site on yeast G-actin by chemical cross-linking. J Mol Biol (2008) 1.09
Targeting of a tropomyosin isoform to short microfilaments associated with the Golgi complex. Mol Biol Cell (2003) 1.08
Arabidopsis Actin-Depolymerizing Factor-4 links pathogen perception, defense activation and transcription to cytoskeletal dynamics. PLoS Pathog (2012) 1.08
Estrogen and aging affect synaptic distribution of phosphorylated LIM kinase (pLIMK) in CA1 region of female rat hippocampus. Neuroscience (2008) 1.08
Does size matter in platelet production? Blood (2012) 1.07
A cellular mechanism for dendritic spine loss in the pilocarpine model of status epilepticus. Epilepsia (2008) 1.07
Toxoplasma gondii actin depolymerizing factor acts primarily to sequester G-actin. J Biol Chem (2009) 1.07
Signaling from the podocyte intercellular junction to the actin cytoskeleton. Semin Nephrol (2012) 1.07
Actin depolymerizing factor controls actin turnover and gliding motility in Toxoplasma gondii. Mol Biol Cell (2011) 1.07
Redox control of vascular smooth muscle migration. Antioxid Redox Signal (2010) 1.06