Published in Proc Natl Acad Sci U S A on September 12, 2000
Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury. BMC Neurosci (2002) 3.21
Genetic analysis of the cytoplasmic dynein subunit families. PLoS Genet (2006) 2.35
The function of activity-regulated genes in the nervous system. Physiol Rev (2009) 1.54
Profile of the genes expressed in the human peripheral retina, macula, and retinal pigment epithelium determined through serial analysis of gene expression (SAGE). Proc Natl Acad Sci U S A (2001) 1.49
Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells. Mol Biol Cell (2005) 1.48
The transcription factor ATF5: role in neurodevelopment and neural tumors. J Neurochem (2008) 1.20
Mst3b, a purine-sensitive Ste20-like protein kinase, regulates axon outgrowth. Proc Natl Acad Sci U S A (2006) 1.19
Neuronal differentiation is regulated by leucine-rich acidic nuclear protein (LANP), a member of the inhibitor of histone acetyltransferase complex. J Biol Chem (2009) 1.03
Human ribosomal protein S13 regulates expression of its own gene at the splicing step by a feedback mechanism. Nucleic Acids Res (2007) 1.01
SH2B1beta (SH2-Bbeta) enhances expression of a subset of nerve growth factor-regulated genes important for neuronal differentiation including genes encoding urokinase plasminogen activator receptor and matrix metalloproteinase 3/10. Mol Endocrinol (2007) 0.98
Increasing the efficiency of SAGE adaptor ligation by directed ligation chemistry. Nucleic Acids Res (2004) 0.94
Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins. BMC Neurosci (2002) 0.94
An integrated approach of differential mass spectrometry and gene ontology analysis identified novel proteins regulating neuronal differentiation and survival. Mol Cell Proteomics (2009) 0.93
Normalization with genes encoding ribosomal proteins but not GAPDH provides an accurate quantification of gene expressions in neuronal differentiation of PC12 cells. BMC Genomics (2010) 0.93
NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation. BMC Genomics (2007) 0.93
A neuroinductive biomaterial based on dopamine. Proc Natl Acad Sci U S A (2006) 0.90
NeuroD6 genomic signature bridging neuronal differentiation to survival via the molecular chaperone network. J Neurosci Res (2010) 0.88
The neurogenic basic helix-loop-helix transcription factor NeuroD6 concomitantly increases mitochondrial mass and regulates cytoskeletal organization in the early stages of neuronal differentiation. ASN Neuro (2009) 0.87
Expression profiling and Ingenuity biological function analyses of interleukin-6- versus nerve growth factor-stimulated PC12 cells. BMC Genomics (2009) 0.84
Impaired regulation of pH homeostasis by oxidative stress in rat brain capillary endothelial cells. Cell Mol Neurobiol (2005) 0.83
Overexpression of 14-3-3z promotes tau phosphorylation at Ser262 and accelerates proteosomal degradation of synaptophysin in rat primary hippocampal neurons. PLoS One (2013) 0.83
Identification of neuronal target genes for CCAAT/enhancer binding proteins. Mol Cell Neurosci (2008) 0.83
Poly(dimethylsiloxane) (PDMS) affects gene expression in PC12 cells differentiating into neuronal-like cells. PLoS One (2013) 0.81
The identification of functional motifs in temporal gene expression analysis. Evol Bioinform Online (2007) 0.79
NGF-induced cell differentiation and gene activation is mediated by integrative nuclear FGFR1 signaling (INFS). PLoS One (2013) 0.78
Trib3 is developmentally and nutritionally regulated in the brain but is dispensable for spatial memory, fear conditioning and sensing of amino acid-imbalanced diet. PLoS One (2014) 0.76
Boolean Modeling Reveals the Necessity of Transcriptional Regulation for Bistability in PC12 Cell Differentiation. Front Genet (2016) 0.75
Induction of serpinb1a by PACAP or NGF is required for PC12 cells survival after serum withdrawal. J Neurochem (2014) 0.75
Serial analysis of gene expression. Science (1995) 60.15
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A (1976) 21.06
Characterization of the yeast transcriptome. Cell (1997) 11.33
Gene expression profiles in normal and cancer cells. Science (1997) 9.65
Analysis of human transcriptomes. Nat Genet (1999) 6.14
Proteins of the ADF/cofilin family: essential regulators of actin dynamics. Annu Rev Cell Dev Biol (1999) 5.76
Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells. J Biol Chem (1985) 4.87
Replication protein A (RPA): the eukaryotic SSB. Crit Rev Biochem Mol Biol (1999) 3.85
Endophilin/SH3p4 is required for the transition from early to late stages in clathrin-mediated synaptic vesicle endocytosis. Neuron (1999) 3.64
A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome. J Cell Biol (2000) 2.98
Intracellular signaling pathways activated by neurotrophic factors. Annu Rev Neurosci (1996) 2.98
Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors. Nature (1990) 2.60
Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues. J Biol Chem (1993) 2.42
Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme. EMBO J (1999) 2.00
Evidence for RNA synthesis-dependent and -independent pathways in stimulation of neurite outgrowth by nerve growth factor. Proc Natl Acad Sci U S A (1978) 2.00
Actin depolymerizing factor and cofilin phosphorylation dynamics: response to signals that regulate neurite extension. Cell Motil Cytoskeleton (1998) 1.96
Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells. Genes Dev (1991) 1.90
The world according to Arp: regulation of actin nucleation by the Arp2/3 complex. Trends Cell Biol (1999) 1.85
Neurotrophin signaling via Trks and p75. Exp Cell Res (1999) 1.65
Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment. Proc Natl Acad Sci U S A (1995) 1.64
Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons. J Neurosci (1997) 1.54
Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development (1998) 1.48
ADP ribosylation factor 1 is required for synaptic vesicle budding in PC12 cells. J Cell Biol (1997) 1.45
Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells. Mol Cell Biol (1987) 1.42
Isolation of a gene encoding a putative leucine zipper structure that is induced by transforming growth factor beta 1 and other growth factors. J Biol Chem (1992) 1.41
Pleiotropic functions of neurotrophins in development. Cytokine Growth Factor Rev (1998) 1.37
14-3-3 proteins in neuronal development and function. Mol Neurobiol (1998) 1.35
Nerve growth factor: two receptors, multiple functions. Bioessays (1998) 1.27
Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies. J Neurochem (1994) 1.21
The DNA polymerase alpha-primase complex couples DNA replication, cell-cycle progression and DNA-damage response. Trends Biochem Sci (1997) 1.17
Molecular analysis of a cytoplasmic dynein light intermediate chain reveals homology to a family of ATPases. J Cell Sci (1995) 1.13
Isolation and characterization of cortactin isoforms and a novel cortactin-binding protein, CBP90. Genes Cells (1998) 1.11
Progression into and out of mitosis. Curr Opin Cell Biol (1999) 1.11
Shortsighted acts in the decapentaplegic pathway in Drosophila eye development and has homology to a mouse TGF-beta-responsive gene. Development (1995) 1.08
Cloning, mapping, expression, function, and mutation analyses of the human ortholog of the hamster putative tumor suppressor gene Doc-1. J Biol Chem (1998) 1.07
Neuroprotection mediated via neurotrophic factors and induction of neurotrophic factors. Brain Res Brain Res Rev (1999) 1.04
The roles of microfilament-associated proteins, drebrins, in brain morphogenesis: a review. J Biochem (1995) 1.03
Transfection with trk restores "slow" NGF binding, efficient NGF uptake, and multiple NGF responses to NGF-nonresponsive PC12 cell mutants. J Neurosci (1993) 1.03
Improved NlaIII digestion of PAGE-purified 102 bp ditags by addition of a single purification step in both the SAGE and microSAGE protocols. Nucleic Acids Res (2000) 1.02
Cloning and sequencing of cDNAs encoding the actin cross-linking protein transgelin defines a new family of actin-associated proteins. Cell Motil Cytoskeleton (1994) 1.01
cDNA clones encoding leucine-zipper proteins which interact with G-CSF gene promoter element 1-binding protein. FEBS Lett (1992) 1.00
HMGI family proteins: architectural transcription factors in mammalian development and cancer. Keio J Med (1998) 1.00
Two antigens recognized by autologous cytolytic T lymphocytes on a melanoma result from a single point mutation in an essential housekeeping gene. Cancer Res (1999) 0.98
The Ras-related GTP-binding protein, Rab1B, regulates early steps in exocytic transport and processing of beta-amyloid precursor protein. J Biol Chem (1995) 0.97
Membrane topology of the 12- and the 25-kDa subunits of the mammalian signal peptidase complex. J Biol Chem (1996) 0.95
Molecular cloning of rat cDNAs for beta and gamma subtypes of 14-3-3 protein and developmental changes in expression of their mRNAs in the nervous system. Brain Res Mol Brain Res (1993) 0.94
Application of a rapid method (targeted display) for the identification of differentially expressed mRNAs following NGF-induced neuronal differentiation in PC12 cells. Mol Cell Neurosci (1999) 0.91
Reduction of ischemic damage in NGF-transgenic mice: correlation with enhancement of antioxidant enzyme activities. Neurobiol Dis (1999) 0.87
The PITSLRE protein kinase family. Prog Cell Cycle Res (1995) 0.84
A novel 39-kDa phosphoribosylpyrophosphate synthetase-associated protein of rat liver. Cloning, high sequence similarity to the catalytic subunits, and a negative regulatory role. J Biol Chem (1994) 0.84
Primary structure of mouse secretogranin III and its absence from deficient mice. J Mol Neurosci (1993) 0.81
Improved restriction landmark cDNA scanning and its application to global analysis of genes regulated by nerve growth factor in PC12 cells. Biochim Biophys Acta (1998) 0.81
Dynamic expression of TSC-22 at sites of epithelial-mesenchymal interactions during mouse development. Mech Dev (1999) 0.80
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A (1976) 21.06
Microtubule assembly in the absence of added nucleotides. Proc Natl Acad Sci U S A (1973) 18.46
Primary care outcomes in patients treated by nurse practitioners or physicians: a randomized trial. JAMA (2000) 9.55
Neurons derived from radial glial cells establish radial units in neocortex. Nature (2001) 7.95
Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene (2006) 5.86
Isolation of a protein subunit from microtubules. J Cell Biol (1967) 5.37
Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules. J Mol Biol (1974) 5.00
Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells. J Biol Chem (1985) 4.87
Effects of mitotic spindle inhibitors on neurotubules and neurofilaments in anterior horn cells. J Cell Biol (1968) 4.65
Intermediate filaments in nervous tissues. J Cell Biol (1978) 3.51
Cytoplasmic filaments and tubules. Fed Proc (1968) 3.22
Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death. J Neurosci (2001) 3.10
An outbreak of waterborne cryptosporidiosis caused by post-treatment contamination. Epidemiol Infect (1989) 3.06
Biochemistry of the filaments of brain. Proc Natl Acad Sci U S A (1976) 3.03
Properties of the protein subunit of central-pair and outer-doublet microtubules of sea urchin flagella. J Cell Biol (1968) 2.91
The mind's scalpel in surgical education: a randomised controlled trial of mental imagery. BJOG (2012) 2.71
The nerve growth factor: biochemistry, synthesis, and mechanism of action. Annu Rev Neurosci (1980) 2.61
Microtubule protein. Identification in and transport to nerve endings. J Cell Biol (1971) 2.58
Interactions of tubulin with vinblastine and guanosine triphosphate. J Mol Biol (1972) 2.49
Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses. Neuron (1994) 2.44
Stimulation of neuronal acetylcholine receptors induces rapid gene transcription. Science (1986) 2.43
Nerve growth factor-induced increase in electrical excitability and acetylcholine sensitivity of a rat pheochromocytoma cell line. Nature (1977) 2.39
A dynein-like protein associated with neurotubules. FEBS Lett (1974) 2.38
Nerve growth factor-induced process formation by cultured rat pheochromocytoma cells. Nature (1975) 2.31
Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism. Neuron (1999) 2.16
Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium. J Cell Biol (1978) 2.16
Binding of nerve growth factor receptor in sympathetic ganglia. Proc Natl Acad Sci U S A (1973) 2.14
The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis. Mol Cell Biol (2001) 2.11
Interactions between neurofilaments and microtubule-associated proteins: a possible mechanism for intraorganellar bridging. J Cell Biol (1982) 2.11
Caspase-2 mediates neuronal cell death induced by beta-amyloid. J Neurosci (2000) 2.10
Changing access to health services in urban China: implications for equity. Health Policy Plan (2001) 2.07
Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily. Curr Biol (1994) 2.05
Localization of bovine brain filament antibody on intermediate (100 A) filaments in guinea pig vascular endothelial cells and chick cardiac muscle cells. Proc Natl Acad Sci U S A (1977) 2.04
Isolation of filaments from brain. Science (1971) 2.03
Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells. Neuron (1993) 2.01
Evidence for RNA synthesis-dependent and -independent pathways in stimulation of neurite outgrowth by nerve growth factor. Proc Natl Acad Sci U S A (1978) 2.00
Regulation of a high molecular weight microtubule-associated protein in PC12 cells by nerve growth factor. J Cell Biol (1983) 1.96
Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles. Proc Natl Acad Sci U S A (2000) 1.81
Release, storage and uptake of catecholamines by a clonal cell line of nerve growth factor (NGF) responsive pheo-chromocytoma cells. Brain Res (1977) 1.80
Sector-wide approaches in developing countries. The aid given must make the most impact. BMJ (2000) 1.78
Heterogeneity of tubulin subunits. Proc Natl Acad Sci U S A (1971) 1.77
Empirical evidence for differential organ reductions during trans-oceanic bird flight. Proc Biol Sci (2000) 1.76
Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis. J Neurosci (1999) 1.75
PC12 cell mutants that possess low- but not high-affinity nerve growth factor receptors neither respond to nor internalize nerve growth factor. J Cell Biol (1986) 1.71
Isolation and characterization of amyloid P component from Alzheimer's disease and other types of cerebral amyloidosis. Lab Invest (1988) 1.70
Is long-distance bird flight equivalent to a high-energy fast? Body composition changes in freely migrating and captive fasting great knots. Physiol Biochem Zool (2001) 1.69
Local cytoplasmic calcium gradients in living mitotic cells. Nature (1985) 1.69
Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity. J Cell Biol (1991) 1.68
Alzheimer's neurofibrillary tangles contain unique epitopes and epitopes in common with the heat-stable microtubule associated proteins tau and MAP2. Am J Pathol (1987) 1.66
Protein changes in senile dementia. Brain Res (1974) 1.65
Neurotrophin signaling via Trks and p75. Exp Cell Res (1999) 1.65
Synthesis, storage and release of acetylcholine by a noradrenergic pheochromocytoma cell line. Nature (1977) 1.58
Changes in the colchicine susceptibility of microtubules associated with neurite outgrowth: studies with nerve growth factor-responsive PC12 pheochromocytoma cells. J Cell Biol (1982) 1.56
Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms. J Neurosci (1991) 1.56
Acidic and basic fibroblast growth factors promote stable neurite outgrowth and neuronal differentiation in cultures of PC12 cells. J Neurosci (1987) 1.56
Chemotherapy for human immunodeficiency virus-associated non-Hodgkin's lymphoma in combination with highly active antiretroviral therapy. J Clin Oncol (2001) 1.55
Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents. J Cell Biol (1998) 1.54
Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons. J Neurosci (1997) 1.54
Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family. J Biol Chem (2001) 1.53
cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor. Proc Natl Acad Sci U S A (1988) 1.52
Comparative genomic hybridization in combination with flow cytometry improves results of cytogenetic analysis of spontaneous abortions. Am J Hum Genet (2000) 1.50
Morphologic and cytochemical properties of a clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Lab Invest (1978) 1.49
Comparison of rapid changes in surface morphology and coated pit formation of PC12 cells in response to nerve growth factor, epidermal growth factor, and dibutyryl cyclic AMP. J Cell Biol (1984) 1.48
Rapid, sequential changes in surface morphology of PC12 pheochromocytoma cells in response to nerve growth factor. J Cell Biol (1979) 1.48
The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines. Cell (1991) 1.47
PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation. Methods Enzymol (1987) 1.47
Biochemical studies on the in vitro assembly and disassembly of microtubules. Ann N Y Acad Sci (1975) 1.46
Growth cone configuration and advance: a time-lapse study using video-enhanced differential interference contrast microscopy. J Neurosci (1988) 1.45
A dissociated cell culture bioassay for nerve growth factor. Neurobiology (1974) 1.45
Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells. Mol Cell Biol (1987) 1.42
Cooperative medical schemes in contemporary rural China. Soc Sci Med (1995) 1.42
Fine structure of initial outgrowth of processes induced in a pheochromocytoma cell line (PC12) by nerve growth factor. J Neurocytol (1979) 1.41
Effect of Nasal Continuous Positive Airway Pressure (NCPAP) Cycling and Continuous NCPAP on Successful Weaning: A Randomized Controlled Trial. Indian J Pediatr (2015) 1.41
Suppression by antisense mRNA demonstrates a requirement for the glial fibrillary acidic protein in the formation of stable astrocytic processes in response to neurons. J Cell Biol (1991) 1.41
Transition from metaphase to anaphase is accompanied by local changes in cytoplasmic free calcium in Pt K2 kidney epithelial cells. Proc Natl Acad Sci U S A (1986) 1.40
Stillbirth in twins, exploring the optimal gestational age for delivery: a retrospective cohort study. BJOG (2014) 1.40
Structure of microtubular crystals induced by vinblastine in vitro. J Cell Biol (1970) 1.39
The Src homology domain 3 (SH3) of a yeast type I myosin, Myo5p, binds to verprolin and is required for targeting to sites of actin polarization. J Cell Biol (1998) 1.39
Factors affecting delays in tuberculosis diagnosis in rural China: a case study in four counties in Shandong Province. Trans R Soc Trop Med Hyg (2005) 1.38
Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons. J Biol Chem (1996) 1.37
Microinjection of Ca++-calmodulin causes a localized depolymerization of microtubules. J Cell Biol (1983) 1.37
NGF stimulates incorporation of fucose or glucosamine into an external glycoprotein in cultured rat PC12 pheochromocytoma cells. Cell (1978) 1.37
A decade of change in obesity surgery. National Bariatric Surgery Registry (NBSR) Contributors. Obes Surg (1997) 1.36
Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation. J Neurosci (2001) 1.36
Regulation of microtubule composition and stability during nerve growth factor-promoted neurite outgrowth. J Cell Biol (1986) 1.35
Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage. J Neurosci (2000) 1.33
Myelin-associated glycoprotein inhibits axonal regeneration from a variety of neurons via interaction with a sialoglycoprotein. Mol Cell Neurosci (1996) 1.33
Neuronal apoptosis at the G1/S cell cycle checkpoint. Cell Tissue Res (2001) 1.33
Astroglia in CNS injury. Glia (1991) 1.32
G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis. J Neurosci (1997) 1.31
Neurofilaments. J Neurochem (1979) 1.31
Fast profilometer for the automatic measurement of 3-D object shapes. Appl Opt (1990) 1.31