Identification and characterization of immunoglobulin G in blood as a major inhibitor of diagnostic PCR.

PubWeight™: 3.02‹?› | Rank: Top 1%

🔗 View Article (PMC 88721)

Published in J Clin Microbiol on January 01, 2000

Authors

W A Al-Soud1, L J Jönsson, P Râdström

Author Affiliations

1: Applied Microbiology, Center for Chemistry, Lund Institute of Technology, Lund University, SE-221 00 Lund, Sweden.

Articles citing this

Pitfalls of quantitative real-time reverse-transcription polymerase chain reaction. J Biomol Tech (2004) 5.97

Purification and characterization of PCR-inhibitory components in blood cells. J Clin Microbiol (2001) 5.78

Loop-mediated isothermal amplification for detection of African trypanosomes. J Clin Microbiol (2003) 3.23

Plasma components affect accuracy of circulating cancer-related microRNA quantitation. J Mol Diagn (2011) 2.57

New tests for syphilis: rational design of a PCR method for detection of Treponema pallidum in clinical specimens using unique regions of the DNA polymerase I gene. J Clin Microbiol (2001) 2.50

Effects of amplification facilitators on diagnostic PCR in the presence of blood, feces, and meat. J Clin Microbiol (2000) 2.37

Laboratory diagnostics of botulism. Clin Microbiol Rev (2006) 2.32

Microarray-based analysis of subnanogram quantities of microbial community DNAs by using whole-community genome amplification. Appl Environ Microbiol (2006) 2.31

Rapid detection of methicillin-resistant staphylococci from blood culture bottles by using a multiplex PCR assay. J Clin Microbiol (2002) 2.19

Molecular dipstick test for diagnosis of sleeping sickness. J Clin Microbiol (2006) 1.84

Molecular detection of Coxiella burnetii in the sera of patients with Q fever endocarditis or vascular infection. J Clin Microbiol (2004) 1.74

Genomic variation of Bartonella henselae strains detected in lymph nodes of patients with cat scratch disease. J Clin Microbiol (2002) 1.73

Identification of serotype in culture negative pneumococcal meningitis using sequential multiplex PCR: implication for surveillance and vaccine design. PLoS One (2008) 1.72

Mutants of Taq DNA polymerase resistant to PCR inhibitors allow DNA amplification from whole blood and crude soil samples. Nucleic Acids Res (2009) 1.72

Microfluidic isolation and transcriptome analysis of serum microvesicles. Lab Chip (2009) 1.61

Quantitation of human immunodeficiency virus type 1 in breast milk. J Clin Microbiol (2003) 1.42

Removal of PCR inhibitors by silica membranes: evaluating the Amplicor Mycobacterium tuberculosis kit. J Clin Microbiol (2001) 1.41

Direct DNA amplification from crude clinical samples using a PCR enhancer cocktail and novel mutants of Taq. J Mol Diagn (2010) 1.13

Quantitative detection of Staphylococcus aureus and Enterococcus faecalis DNA in blood to diagnose bacteremia in patients in the intensive care unit. J Clin Microbiol (2007) 1.13

Preparation of bacterial DNA template by boiling and effect of immunoglobulin G as an inhibitor in real-time PCR for serum samples from patients with brucellosis. Clin Vaccine Immunol (2007) 1.08

Automated extraction improves multiplex molecular detection of infection in septic patients. PLoS One (2010) 1.06

Development of a combined selection and enrichment PCR procedure for Clostridium botulinum Types B, E, and F and its use to determine prevalence in fecal samples from slaughtered pigs. Appl Environ Microbiol (2001) 1.05

Detection of Mycobacterium tuberculosis in blood by use of the Xpert MTB/RIF assay. J Clin Microbiol (2013) 1.03

Selective enrichment and detection of mycobacterial DNA in paucibacillary specimens. J Microbiol Methods (2006) 1.01

Rapid detection of blaKPC carbapenemase genes by internally controlled real-time PCR assay using bactec blood culture bottles. J Clin Microbiol (2011) 0.99

Highly sensitive detection of Staphylococcus aureus directly from patient blood. PLoS One (2012) 0.98

Phage-based platforms for the clinical detection of human bacterial pathogens. Bacteriophage (2012) 0.98

Sensitive PCR-based quantitation of cell-free circulating microRNAs. Methods (2012) 0.98

Prevalence of Trypanosoma sp. in cattle from Tanzania estimated by conventional PCR and loop-mediated isothermal amplification (LAMP). Parasitol Res (2011) 0.97

Identification of human pathogens isolated from blood using microarray hybridisation and signal pattern recognition. BMC Microbiol (2007) 0.96

Andes virus antigens are shed in urine of patients with acute hantavirus cardiopulmonary syndrome. J Virol (2009) 0.94

Molecular breeding of polymerases for resistance to environmental inhibitors. Nucleic Acids Res (2011) 0.93

Application of loop-mediated isothermal amplification for malaria diagnosis during a follow-up study in São Tomé. Malar J (2012) 0.92

An inexpensive and rapid diagnostic method of Koi Herpesvirus (KHV) infection by loop-mediated isothermal amplification. Virol J (2005) 0.92

External quality assurance of malaria nucleic acid testing for clinical trials and eradication surveillance. PLoS One (2014) 0.92

Evaluation of four different systems for extraction of RNA from stool suspensions using MS-2 coliphage as an exogenous control for RT-PCR inhibition. PLoS One (2012) 0.91

Occurrence of false positives during testing for antibodies to hepatitis C virus among volunteer blood donors in India. J Clin Microbiol (2003) 0.90

Comparison of two real-time quantitative assays for detection of severe acute respiratory syndrome coronavirus. J Clin Microbiol (2004) 0.90

Loop-mediated isothermal amplification assay for rapid diagnosis of malaria infections in an area of endemicity in Thailand. J Clin Microbiol (2014) 0.90

New detection modality for label-free quantification of DNA in biological samples via superparamagnetic bead aggregation. J Am Chem Soc (2012) 0.87

Rapid and specific detection of Salmonella spp. in animal feed samples by PCR after culture enrichment. Appl Environ Microbiol (2004) 0.85

Rapid detection of hepatitis B virus in blood plasma by a specific and sensitive loop-mediated isothermal amplification assay. Clin Infect Dis (2014) 0.84

1,2-propanediol-trehalose mixture as a potent quantitative real-time PCR enhancer. BMC Biotechnol (2011) 0.82

Development and validation of a quantitative PCR assay using multiplexed hydrolysis probes for detection and quantification of Theileria orientalis isolates and differentiation of clinically relevant subtypes. J Clin Microbiol (2015) 0.81

Circulating miRNA signatures of early pregnancy in cattle. BMC Genomics (2016) 0.81

Compartmentalized self-replication under fast PCR cycling conditions yields Taq DNA polymerase mutants with increased DNA-binding affinity and blood resistance. Front Microbiol (2014) 0.79

Shortcut method for extraction of Staphylococcus aureus DNA from blood cultures and conventional cultures for use in real-time PCR assays. J Clin Microbiol (2005) 0.78

Cerebrospinal fluid can be used for HIV genotyping when it fails in blood. Arq Neuropsiquiatr (2014) 0.78

Degradation of intestinal mRNA: a matter of treatment. World J Gastroenterol (2015) 0.78

Evaluation of PCR-reverse blot hybridization assay, REBA Sepsis-ID test, for simultaneous identification of bacterial pathogens and mecA and van genes from blood culture bottles. Ann Lab Med (2014) 0.77

Assessment of a semi-automated protocol for multiplex analysis of sepsis-causing bacteria with spiked whole blood samples. Microbiologyopen (2013) 0.76

Bacterial communities associated with apical periodontitis and dental implant failure. Microb Ecol Health Dis (2016) 0.75

Establishment of two quantitative nested qPCR assays targeting the human EPO transgene. Gene Ther (2016) 0.75

Direct polymerase chain reaction from blood and tissue samples for rapid diagnosis of bovine leukemia virus infection. J Vet Med Sci (2016) 0.75

Loop Mediated Isothermal Amplification for Detection of Trypanosoma brucei gambiense in Urine and Saliva Samples in Nonhuman Primate Model. Biomed Res Int (2015) 0.75

PCR Inhibition of a Quantitative PCR for Detection of Mycobacterium avium Subspecies Paratuberculosis DNA in Feces: Diagnostic Implications and Potential Solutions. Front Microbiol (2017) 0.75

A localized PCR inhibitor in a porcelain crab suggests a protective role. PeerJ (2014) 0.75

Reliability of molecular host-identification methods for ticks: an experimental in vitro study with Ixodes ricinus. Parasit Vectors (2015) 0.75

Recovery of small DNA fragments from serum using compaction precipitation. PLoS One (2012) 0.75

Evaluation of four molecular methods for the diagnosis of tuberculosis in pulmonary and blood samples from immunocompromised patients. Mem Inst Oswaldo Cruz (2014) 0.75

Molecular survey of Coxiella burnetii in wildlife and ticks at wildlife-livestock interfaces in Kenya. Exp Appl Acarol (2017) 0.75

Comparative evaluation of two Rickettsia typhi-specific quantitative real-time PCRs for research and diagnostic purposes. Med Microbiol Immunol (2016) 0.75

Is the detection of aquatic environmental DNA influenced by substrate type? PLoS One (2017) 0.75

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

Inhibition and facilitation of nucleic acid amplification. Appl Environ Microbiol (1997) 9.00

Inhibition of PCR by components of food samples, microbial diagnostic assays and DNA-extraction solutions. Int J Food Microbiol (1992) 4.44

PCR based diagnosis in the presence of 8% (v/v) blood. Nucleic Acids Res (1991) 4.06

Identification of the heme compound copurified with deoxyribonucleic acid (DNA) from bloodstains, a major inhibitor of polymerase chain reaction (PCR) amplification. J Forensic Sci (1994) 4.02

High resolution two-dimensional electrophoresis of human plasma proteins. Proc Natl Acad Sci U S A (1977) 2.97

Capacity of nine thermostable DNA polymerases To mediate DNA amplification in the presence of PCR-inhibiting samples. Appl Environ Microbiol (1998) 2.93

Detection of bacterial DNA in cerebrospinal fluid by an assay for simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and streptococci using a seminested PCR strategy. J Clin Microbiol (1994) 2.69

Inhibition of PCR by aqueous and vitreous fluids. J Clin Microbiol (1995) 2.35

A potent inhibitor of Taq polymerase copurifies with human genomic DNA. Nucleic Acids Res (1988) 2.26

Detection of Streptococcus pneumoniae in whole blood by PCR. J Clin Microbiol (1995) 2.24

DNA enzyme immunoassay: general method for detecting products of polymerase chain reaction. Clin Chem (1991) 2.12

Reverse transcriptase (RT) inhibition of PCR at low concentrations of template and its implications for quantitative RT-PCR. Appl Environ Microbiol (1998) 1.77

Novel vectors for the expression of antibody molecules using variable regions generated by polymerase chain reaction. J Immunol Methods (1992) 1.74

Detection of Streptococcus pneumoniae DNA in blood cultures by PCR. J Clin Microbiol (1994) 1.69

TaqStart Antibody: "hot start" PCR facilitated by a neutralizing monoclonal antibody directed against Taq DNA polymerase. Biotechniques (1994) 1.54

Enhanced sensitivity in PCR detection of Listeria monocytogenes in soft cheese through use of an aqueous two-phase system as a sample preparation method. Appl Environ Microbiol (1994) 1.48

A distinctive property of Tth DNA polymerase: enzymatic amplification in the presence of phenol. Biotechniques (1994) 1.45

Comparison of methods for extraction of nucleic acid from hemolytic serum for PCR amplification of hepatitis B virus DNA sequences. J Clin Microbiol (1997) 1.39

Detection of gene expression by PCR amplification of RNA derived from frozen heparinized whole blood. Nucleic Acids Res (1991) 1.33

Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies. J Virol (1993) 1.32

Reverse transcriptase inhibits Taq polymerase activity. Nucleic Acids Res (1992) 1.18

Continuous RT-PCR using AMV-RT and Taq DNA polymerase: characterization and comparison to uncoupled procedures. Biotechniques (1995) 1.14

Light chain shuffling of a high affinity antibody results in a drift in epitope recognition. Mol Immunol (1996) 1.14

A two-dimensional gel database of human plasma proteins. Electrophoresis (1991) 1.05

Evaluation of novel control elements by construction of eukaryotic expression vectors. Gene (1997) 0.85