Published in Int J Obes Relat Metab Disord on December 01, 1999
PPARs in the Control of Uncoupling Proteins Gene Expression. PPAR Res (2007) 1.34
Genetic predisposition in NAFLD and NASH: impact on severity of liver disease and response to treatment. Curr Pharm Des (2013) 1.16
Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation. Cancer Chemother Pharmacol (2010) 1.10
The combined impact of metabolic gene polymorphisms on elite endurance athlete status and related phenotypes. Hum Genet (2009) 1.06
Mitochondrial uncoupling proteins and energy metabolism. Front Physiol (2015) 1.00
Population genetic analysis of the uncoupling proteins supports a role for UCP3 in human cold resistance. Mol Biol Evol (2010) 0.99
Variation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: the Finnish Diabetes Prevention Study. BMC Med Genet (2009) 0.96
Further support to the uncoupling-to-survive theory: the genetic variation of human UCP genes is associated with longevity. PLoS One (2011) 0.93
Associations between UCP1 -3826A/G, UCP2 -866G/A, Ala55Val and Ins/Del, and UCP3 -55C/T polymorphisms and susceptibility to type 2 diabetes mellitus: case-control study and meta-analysis. PLoS One (2013) 0.90
Four novel UCP3 gene variants associated with childhood obesity: effect on fatty acid oxidation and on prevention of triglyceride storage. Int J Obes (Lond) (2011) 0.82
UCP2 -866G/A, Ala55Val and UCP3 -55C/T polymorphisms in association with obesity susceptibility - a meta-analysis study. PLoS One (2013) 0.82
Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians. Biogerontology (2016) 0.80
The energy intake modulates the association of the -55CT polymorphism of UCP3 with body weight in type 2 diabetic patients. Int J Obes (Lond) (2013) 0.77
Association between UCP3 gene polymorphisms and nonalcoholic fatty liver disease in Chinese children. World J Gastroenterol (2013) 0.77
The genetic association study between polymorphisms in uncoupling protein 2 and uncoupling protein 3 and metabolic data in dogs. BMC Res Notes (2014) 0.77
Short report: Tissue-specific expression profiles of the uncoupling protein family in normal control mice and genetically ob/ob mice. J Bioenerg Biomembr (2010) 0.77
Examining for an association between candidate gene polymorphisms in the metabolic syndrome components on excess weight and adiposity measures in youth: a cross-sectional study. Genes Nutr (2017) 0.75
Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med (1995) 8.51
Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians. N Engl J Med (1993) 6.89
Atom transfer radical polymerization. Chem Rev (2001) 6.31
Determinants of 24-hour energy expenditure in man. Methods and results using a respiratory chamber. J Clin Invest (1986) 5.18
Circulating ghrelin levels are decreased in human obesity. Diabetes (2001) 4.28
Interaction of the N-ethylmaleimide-sensitive factor with AMPA receptors. Neuron (1998) 3.90
Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins. J Neurosci (2000) 3.44
Energy expenditure by doubly labeled water: validation in humans and proposed calculation. Am J Physiol (1986) 3.35
Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ. Am J Physiol (1990) 3.01
Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest (1990) 2.63
Neuroanatomical correlates of hunger and satiation in humans using positron emission tomography. Proc Natl Acad Sci U S A (1999) 2.55
Body mass index as a measure of adiposity in children and adolescents: relationship to adiposity by dual energy x-ray absorptiometry and to cardiovascular risk factors. J Clin Endocrinol Metab (2001) 2.52
Regulation of the B cell response to T-dependent antigens by classical pathway complement. J Immunol (1996) 2.51
Is a low leptin concentration, a low resting metabolic rate, or both the expression of the "thrifty genotype"? Results from Mexican Pima Indians. Am J Clin Nutr (1998) 2.42
Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus. Int J Obes Relat Metab Disord (2004) 2.40
Twenty-four-hour energy expenditure and resting metabolic rate in obese, moderately obese, and control subjects. Am J Clin Nutr (1982) 2.37
Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen. Immunity (1996) 2.29
Effect of satiation on brain activity in obese and lean women. Obes Res (2001) 2.25
An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians. J Clin Invest (1998) 2.18
Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules. J Biol Chem (2000) 2.18
Ginsenoside-Rd improves outcome of acute ischaemic stroke - a randomized, double-blind, placebo-controlled, multicenter trial. Eur J Neurol (2012) 2.18
Retracted CCR5 blockade in combination with rapamycin prolongs cardiac allograft survival in mice. Clin Exp Immunol (2009) 2.06
Energy metabolism in African Americans: potential risk factors for obesity. Am J Clin Nutr (1999) 2.03
Use of dual-energy X-ray absorptiometry in obese individuals. Am J Clin Nutr (1995) 2.02
Insulin resistance associated with lower rates of weight gain in Pima Indians. J Clin Invest (1991) 2.02
Familial dependence of the resting metabolic rate. N Engl J Med (1986) 1.94
Effects of glucocorticoids on energy metabolism and food intake in humans. Am J Physiol (1996) 1.86
Higher sedentary energy expenditure in patients with Huntington's disease. Ann Neurol (2000) 1.86
Differential brain responses to satiation in obese and lean men. Diabetes (2000) 1.81
Body weight gain in free-living Pima Indians: effect of energy intake vs expenditure. Int J Obes Relat Metab Disord (2003) 1.79
Autosomal genomic scan for loci linked to obesity and energy metabolism in Pima Indians. Am J Hum Genet (1998) 1.78
Dye tracers define differential endothelial and smooth muscle coupling patterns within the arteriolar wall. Circ Res (1995) 1.73
A high concentration of fasting plasma non-esterified fatty acids is a risk factor for the development of NIDDM. Diabetologia (1995) 1.70
Racial differences in the relation between blood pressure and insulin resistance. N Engl J Med (1991) 1.68
MinK-KvLQT1 fusion proteins, evidence for multiple stoichiometries of the assembled IsK channel. J Biol Chem (1998) 1.64
Relationship between serum resistin concentrations and insulin resistance in nonobese, obese, and obese diabetic subjects. J Clin Endocrinol Metab (2004) 1.63
Energy intake and physical activity in Pima Indians: comparison with energy expenditure measured by doubly-labeled water. Obes Res (1994) 1.58
Daily energy expenditure in Mexican and USA Pima indians: low physical activity as a possible cause of obesity. Int J Obes Relat Metab Disord (2000) 1.55
A comparative study of different means of assessing long-term energy expenditure in humans. Am J Physiol (1996) 1.52
Determinants of energy expenditure and fuel utilization in man: effects of body composition, age, sex, ethnicity and glucose tolerance in 916 subjects. Int J Obes Relat Metab Disord (1999) 1.51
Energy metabolism after 2 y of energy restriction: the biosphere 2 experiment. Am J Clin Nutr (2000) 1.50
Early markers for protective mechanisms during rush venom immunotherapy. Allergy (2010) 1.50
Energy expenditure, fat oxidation, and body weight regulation: a study of metabolic adaptation to long-term weight change. J Clin Endocrinol Metab (2000) 1.49
Energy cost of physical activity on a metabolic ward in relationship to obesity. Am J Clin Nutr (1991) 1.48
Formation of C7F15COOH (PFOA) and other perfluorocarboxylic acids during the atmospheric oxidation of 8:2 fluorotelomer alcohol. Environ Sci Technol (2006) 1.46
Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes. Diabetologia (2004) 1.43
Energy expenditure before and during energy restriction in obese patients. Am J Clin Nutr (1985) 1.42
Cloning and characterization of PDK4 on 7q21.3 encoding a fourth pyruvate dehydrogenase kinase isoenzyme in human. J Biol Chem (1996) 1.41
Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians. Hum Mol Genet (1998) 1.40
Presynaptic clustering of mGluR7a requires the PICK1 PDZ domain binding site. Neuron (2000) 1.39
Energy metabolism, fuel selection and body weight regulation. Int J Obes (Lond) (2008) 1.39
Drug delivery systems: water soluble taxol 2'-poly(ethylene glycol) ester prodrugs-design and in vivo effectiveness. J Med Chem (1996) 1.38
Decreased expression of apM1 in omental and subcutaneous adipose tissue of humans with type 2 diabetes. Int J Exp Diabetes Res (2000) 1.36
Effect of muscle glycogen depletion on in vivo insulin action in man. J Clin Invest (1983) 1.35
Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. A potential mechanism for insulin resistance in the polycystic ovary syndrome. J Clin Invest (1995) 1.32
Determinants of total daily energy expenditure: variability in physical activity. Am J Clin Nutr (1994) 1.29
Fasting hyperinsulinemia is a predictor of increased body weight gain and obesity in Pima Indian children. Diabetes (1997) 1.26
Increase in insulin action and fat oxidation after treatment with CL 316,243, a highly selective beta3-adrenoceptor agonist in humans. Diabetes (1998) 1.26
Familiality of physical and metabolic characteristics that predict the development of non-insulin-dependent diabetes mellitus in Pima Indians. Am J Hum Genet (1997) 1.25
Lower daily energy expenditure as measured by a respiratory chamber in subjects with spinal cord injury compared with control subjects. Am J Clin Nutr (1998) 1.25
Thermic effect of food in humans: methods and results from use of a respiratory chamber. Am J Clin Nutr (1995) 1.24
Confirmed angiosarcoma: prognostic factors and outcome in 50 prospectively followed patients. Sarcoma (2000) 1.24
Influence of age, sex, and insulin on osteoblast function: osteoblast dysfunction in diabetes mellitus. J Clin Endocrinol Metab (1995) 1.24
Short-term energy balance: relationship with protein, carbohydrate, and fat balances. Am J Physiol (1988) 1.23
Reduced insulin secretion: an independent predictor of body weight gain. J Clin Endocrinol Metab (1995) 1.21
Spontaneous physical activity and obesity: cross-sectional and longitudinal studies in Pima Indians. Am J Physiol (1992) 1.19
Energy expenditure of elite female runners measured by respiratory chamber and doubly labeled water. J Appl Physiol (1985) (1992) 1.17
Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Pima Diabetes Gene Group. Am J Hum Genet (1997) 1.17
Design, synthesis, and evaluation of metabolism-based analogues of haloperidol incapable of forming MPP+-like species. J Med Chem (2004) 1.15
Cephalometric norms for the upper airway in a healthy Hong Kong Chinese population. Hong Kong Med J (2003) 1.15
Thermic effect of infused glucose and insulin in man. Decreased response with increased insulin resistance in obesity and noninsulin-dependent diabetes mellitus. J Clin Invest (1983) 1.15
Lower sedentary metabolic rate in women compared with men. J Clin Invest (1992) 1.14
Aging and energy expenditure. Am J Clin Nutr (1991) 1.14
Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians. J Clin Invest (1995) 1.13
The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcript. J Biol Chem (2000) 1.13
Nutritional influences on lipogenesis and thermogenesis after a carbohydrate meal. Am J Physiol (1984) 1.13
The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetes. Diabetologia (2005) 1.12
Reduced sympathetic nervous activity. A potential mechanism predisposing to body weight gain. J Clin Invest (1993) 1.12
Ubiquitin D is correlated with colon cancer progression and predicts recurrence for stage II-III disease after curative surgery. Br J Cancer (2010) 1.11
Effects of dietary fat on postprandial substrate oxidation and on carbohydrate and fat balances. J Clin Invest (1985) 1.11
Concomitant interindividual variation in body temperature and metabolic rate. Am J Physiol (1992) 1.11
The thermic effect of carbohydrate versus fat feeding in man. Metabolism (1985) 1.10
Endometrial stromal sarcoma: objective response to letrozole. Gynecol Oncol (2001) 1.08
Serine racemase binds to PICK1: potential relevance to schizophrenia. Mol Psychiatry (2006) 1.08
Racial difference in body core temperature between Pima Indian and Caucasian men. Int J Obes Relat Metab Disord (1995) 1.08
Relationship between skeletal muscle lipoprotein lipase activity and 24-hour macronutrient oxidation. J Clin Invest (1993) 1.08
Effects of physical training and diet therapy on carbohydrate metabolism in patients with glucose intolerance and non-insulin-dependent diabetes mellitus. Diabetes (1984) 1.07
The huntingtin N17 domain is a multifunctional CRM1 and Ran-dependent nuclear and cilial export signal. Hum Mol Genet (2013) 1.07
An autosomal genomic scan for loci linked to plasma leptin concentration in Pima Indians. Int J Obes Relat Metab Disord (2000) 1.06
Thermic effect of glucose in man. Obligatory and facultative thermogenesis. J Clin Invest (1984) 1.05
Frequency of SCA1, SCA2, SCA3/MJD, SCA6, SCA7, and DRPLA CAG trinucleotide repeat expansion in patients with hereditary spinocerebellar ataxia from Chinese kindreds. Arch Neurol (2000) 1.05
Characterization of the interaction between the nuclease and reverse transcriptase activity of the yeast telomerase complex. Mol Cell Biol (2000) 1.04
Metabolically healthy and unhealthy obese--the 2013 Stock Conference report. Obes Rev (2014) 1.04
Physical activity, genetic, and nutritional considerations in childhood weight management. Med Sci Sports Exerc (1998) 1.04