Published in Am J Physiol Heart Circ Physiol on January 01, 2000
Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol. Proc Natl Acad Sci U S A (2003) 1.87
Pathways to ischemic neuronal cell death: are sex differences relevant? J Transl Med (2008) 1.71
Changes in experimental stroke outcome across the life span. J Cereb Blood Flow Metab (2009) 1.58
Sex, sex steroids, and brain injury. Semin Reprod Med (2009) 1.35
Mechanisms of gender-linked ischemic brain injury. Restor Neurol Neurosci (2009) 1.24
Alterations in EDHF-mediated hyperpolarization and relaxation in mesenteric arteries of female rats in long-term deficiency of oestrogen and during oestrus cycle. Br J Pharmacol (2001) 1.20
Rodent models of focal cerebral ischemia: procedural pitfalls and translational problems. Exp Transl Stroke Med (2009) 1.11
Differential effects of aging and sex on stroke induced inflammation across the lifespan. Exp Neurol (2013) 1.03
Central and peripheral neuroimmune responses: hyporesponsiveness during pregnancy. J Physiol (2007) 1.02
Sexual dimorphism in ischemic stroke: lessons from the laboratory. Womens Health (Lond Engl) (2011) 1.00
Neuroprotection of sex steroids. Minerva Endocrinol (2010) 0.99
Mild hypothermia attenuates mitochondrial oxidative stress by protecting respiratory enzymes and upregulating MnSOD in a pig model of cardiac arrest. PLoS One (2012) 0.98
Sex differences in ischemic stroke sensitivity are influenced by gonadal hormones, not by sex chromosome complement. J Cereb Blood Flow Metab (2014) 0.97
Substrain differences, gender, and age of spontaneously hypertensive rats critically determine infarct size produced by distal middle cerebral artery occlusion. Cell Mol Neurobiol (2004) 0.89
The assessment of non-feminizing estrogens for use in neuroprotection. Brain Res (2010) 0.87
Lack of correlation of vaginal impedance measurements with hormone levels in the rat. Contemp Top Lab Anim Sci (2005) 0.87
The potential for estrogens in preventing Alzheimer's disease and vascular dementia. Ther Adv Neurol Disord (2009) 0.87
Intact female stroke-prone hypertensive rats lack responsiveness to mineralocorticoid receptor antagonists. Am J Physiol Regul Integr Comp Physiol (2007) 0.87
A high soy diet enhances neurotropin receptor and Bcl-XL gene expression in the brains of ovariectomized female rats. Brain Res (2007) 0.85
Oestrogen signalling and neuroprotection in cerebral ischaemia. J Neuroendocrinol (2012) 0.83
X chromosome dosage and the response to cerebral ischemia. J Neurosci (2011) 0.83
Effects of global cerebral ischemia in the pregnant rat. Stroke (2008) 0.82
Neuroprotection with non-feminizing estrogen analogues: an overlooked possible therapeutic strategy. Horm Behav (2012) 0.80
The effects of soy extract on spatial learning and memory damage induced by global ischemia in ovariectomised rats. Malays J Med Sci (2014) 0.80
The Importance of Considering Sex Differences in Translational Stroke Research. Transl Stroke Res (2016) 0.78
rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. Biol Sex Differ (2014) 0.76
Effects of sex steroid hormones on neuromedin S and neuromedin U2 receptor expression following experimental traumatic brain injury. Iran J Basic Med Sci (2016) 0.75
Strain and sex based characterization of behavioral expressions in non-induced compulsive-like mice. Physiol Behav (2016) 0.75
A novel mechanism of non-feminizing estrogens in neuroprotection. Exp Gerontol (2016) 0.75
Menopause and Ischemic Stroke: A Brief Review. MOJ Toxicol (2017) 0.75
Effect of renal-artery stenting on progression of renovascular renal failure. Lancet (1997) 3.89
Glomerular hyperfiltration: a new marker of metabolic risk. Kidney Int (2007) 3.17
Better blood pressure control: how to combine drugs. J Hum Hypertens (2003) 2.19
Estrogen as a neuroprotectant in stroke. J Cereb Blood Flow Metab (2000) 2.03
Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. Hypertension (2001) 1.97
Families of patients with premature coronary heart disease: an obvious but neglected target for primary prevention. BMJ (2007) 1.63
Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries. Circulation (2000) 1.54
Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium. Hypertension (1999) 1.44
Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide. Am J Physiol Heart Circ Physiol (2001) 1.41
Endothelial function in hypertension: the role of superoxide anion. Hypertension (1999) 1.33
Neuroprotection by a selective estrogen receptor beta agonist in a mouse model of global ischemia. Am J Physiol Heart Circ Physiol (2004) 1.24
Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia. Stroke (2001) 1.24
Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus. Nat Genet (1997) 1.18
Role of superoxide in the depressed nitric oxide production by the endothelium of genetically hypertensive rats. Hypertension (1995) 1.17
Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus. Mol Ther (2001) 1.08
Blood pressure in genetically hypertensive rats. Influence of the Y chromosome. Hypertension (1995) 1.05
Oxidative stress and vascular damage in hypertension. Curr Opin Nephrol Hypertens (2001) 1.04
Cellular aspects of vascular remodeling in hypertension revealed by confocal microscopy. Hypertension (1997) 1.04
Influence of ischemia and reperfusion on the course of brain tissue swelling and blood-brain barrier permeability in a rodent model of transient focal cerebral ischemia. Exp Neurol (1997) 1.03
Release of noradrenaline and dopamine by nerve stimulation in the guinea-pig and rat vas deferens. Br J Pharmacol (1984) 1.02
Distribution of subgroups of noradrenaline neurons in the coeliac ganglion of the guinea-pig. Cell Tissue Res (1986) 1.02
Brain aromatase expression after experimental stroke: topography and time course. J Steroid Biochem Mol Biol (2005) 1.01
Quantitative trait loci in genetically hypertensive rats. Possible sex specificity. Hypertension (1996) 1.01
Characterization of the microglial response to cerebral ischemia in the stroke-prone spontaneously hypertensive rat. Hypertension (2001) 0.98
Genetic and gender influences on sensitivity to focal cerebral ischemia in the stroke-prone spontaneously hypertensive rat. Hypertension (1999) 0.98
Inhibition of nitric oxide synthesis does not reduce infarct volume in a rat model of focal cerebral ischaemia. Neurosci Lett (1992) 0.98
Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of hypertension. Gene Ther (2002) 0.95
Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat. Diabetes (2000) 0.94
Plasma angiotensin II, predisposition to hypertension, and left ventricular size in healthy young adults. Circulation (1996) 0.94
Cellular changes induced by chronic nitric oxide inhibition in intact rat basilar arteries revealed by confocal microscopy. J Hypertens (1997) 0.93
Cerebral small vessel endothelial structural changes predate hypertension in stroke-prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5- to 21-week-old rats. Neuropathol Appl Neurobiol (2011) 0.92
Pathophysiology of the vasculature in hypertension. Hypertension (1991) 0.92
Renal, cardiovascular and hormonal characteristics of young adults with autosomal dominant polycystic kidney disease. Kidney Int (1991) 0.92
Specific expression of the cell cycle regulation proteins, GADD34 and PCNA, in the peri-infarct zone after focal cerebral ischaemia in the rat. Eur J Neurosci (2002) 0.92
Applicability of a "speed" congenic strategy to dissect blood pressure quantitative trait loci on rat chromosome 2. Hypertension (2000) 0.92
Confocal microscopic characterization of a lesion in a cerebral vessel of the stroke-prone spontaneously hypertensive rat. Stroke (1996) 0.91
Reduction of local cerebral blood flow to pathological levels by endothelin-1 applied to the middle cerebral artery in the rat. Neurosci Lett (1990) 0.91
Analysis of cell-specific promoters for viral gene therapy targeted at the vascular endothelium. Hypertension (2001) 0.90
Susceptibility to cerebral infarction in the stroke-prone spontaneously hypertensive rat is inherited as a dominant trait. Stroke (1998) 0.90
Investigation of estrogen status and increased stroke sensitivity on cerebral blood flow after a focal ischemic insult. J Cereb Blood Flow Metab (2000) 0.90
Impaired functional recovery after stroke in the stroke-prone spontaneously hypertensive rat. Stroke (2004) 0.90
Heritability of chronic pain in 2195 extended families. Eur J Pain (2012) 0.90
The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat. Neurosci Lett (1995) 0.89
Effects of nitric oxide and superoxide on relaxation in human artery and vein. Atherosclerosis (1997) 0.88
Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion. Br J Pharmacol (1997) 0.88
The cardiovascular actions of clonidine and neuropeptide-Y in the ventrolateral medulla of the rat. Br J Pharmacol (1989) 0.88
Vascular function in patients with end-stage renal disease and/or coronary artery disease: a cardiac magnetic resonance imaging study. Kidney Int (2006) 0.87
Sex differences in the abundance of endothelial nitric oxide in a model of genetic hypertension. Hypertension (1997) 0.87
Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study. Clin Endocrinol (Oxf) (2007) 0.87
Telemetry for cardiovascular monitoring in a pharmacological study: new approaches to data analysis. Hypertension (1999) 0.86
Reciprocal consomic strains to evaluate y chromosome effects. Hypertension (2001) 0.86
Endothelial FOS expression and pre-eclampsia. BJOG (2012) 0.86
Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo. Am J Physiol (1998) 0.85
Sex hormones induce insulin resistance in 3T3-L1 adipocytes by reducing cellular content of IRS proteins. Diabetologia (2000) 0.85
Anti-ischaemic efficacy of a nitric oxide synthase inhibitor and a N-methyl-D-aspartate receptor antagonist in models of transient and permanent focal cerebral ischaemia. Br J Pharmacol (1994) 0.84
Optimized protocols for typing 75 microsatellite loci in AS, PVG, F344, and BN rats. Mamm Genome (1995) 0.84
DNA synthesis and apoptosis in smooth muscle cells from a model of genetic hypertension. Hypertension (2000) 0.83
Genes encoding atrial and brain natriuretic peptides as candidates for sensitivity to brain ischemia in stroke-prone hypertensive rats. Hypertension (1999) 0.83
ESC-BRAIN: experimental and clinical stroke research--do they connect?. Meeting report of the ESC-BRAIN joint symposium held in London and Shanghai in May 2013. Cerebrovasc Dis (2013) 0.83
Skeletal muscle of stroke-prone spontaneously hypertensive rats exhibits reduced insulin-stimulated glucose transport and elevated levels of caveolin and flotillin. Diabetes (2001) 0.83
Renin angiotensin system inhibition is associated with reduced free radical concentrations in arteries of patients with coronary heart disease. Heart (2001) 0.83
Gene transfer of endothelial nitric oxide synthase improves nitric oxide-dependent endothelial function in a hypertensive rat model. Cardiovasc Res (1999) 0.83
Is hydrogen peroxide an EDHF in human radial arteries? Am J Physiol Heart Circ Physiol (2001) 0.82
Gene transfer of endothelial nitric oxide synthase but not Cu/Zn superoxide dismutase restores nitric oxide availability in the SHRSP. Cardiovasc Res (2000) 0.82
Endothelin, cerebral ischaemia and infarction. Clin Exp Hypertens (1995) 0.82
Impaired cerebral autoregulation 24 h after induction of transient unilateral focal ischaemia in the rat. Eur J Neurosci (2000) 0.81
Oxidized-LDL induced changes in membrane physico-chemical properties and [Ca2+]i of bovine aortic endothelial cells. Influence of vitamin E. Atherosclerosis (1995) 0.81
Differences in inositol phosphate production in blood vessels of normotensive and spontaneously hypertensive rats. Br J Pharmacol (1991) 0.81
Cell membrane abnormalities and the regulation of intracellular calcium concentration in hypertension. Clin Sci (Lond) (1990) 0.81
Increased Na(+)/H(+) exchanger isoform 1 activity in spontaneously hypertensive rats: lack of mutations within the coding region of NHE1. Biochim Biophys Acta (2000) 0.81
Cobalt contraction of vascular smooth muscle is calcium dependent. J Cardiovasc Pharmacol (1994) 0.80
Altered Na+-K+ pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene. Physiol Genomics (2001) 0.80
Identification of a common low density lipoprotein receptor mutation (C163Y) in the west of Scotland. J Med Genet (1998) 0.80
Inducible L-arginine/nitric oxide pathway in human internal mammary artery and saphenous vein. Am J Physiol (1995) 0.80
Identification of the growth arrest and DNA damage protein GADD34 in the normal human heart and demonstration of alterations in expression following myocardial ischaemia. Int J Cardiol (2006) 0.79
Membrane microviscosity does not correlate with blood pressure: a cosegregation study. J Hypertens (1993) 0.79
Radial artery hypertrophy occurs in coronary atherosclerosis and is independent of blood pressure. Clin Sci (Lond) (2001) 0.79
LB01.03: INCIDENCE AND PROGNOSIS OF CANCER ASSOCIATED WITH DIGOXIN AND COMMON ANTIHYPERTENSIVE DRUGS. J Hypertens (2015) 0.78
Vascular smooth muscle polyploidy in genetic hypertension: the role of angiotensin II. J Hum Hypertens (1995) 0.78
The effects of perindopril on vascular smooth muscle polyploidy in stroke-prone spontaneously hypertensive rats. J Hypertens (1995) 0.78
The selective oestrogen receptor modulator, LY362321, is not neuroprotective in a rat model of transient focal ischaemia. J Neuroendocrinol (2008) 0.78
Genetics of hypertension: from experimental models to clinical applications. J Hum Hypertens (2001) 0.78
Insulin resistance, hypertension and the insulin-responsive glucose transporter, GLUT4. Clin Sci (Lond) (1995) 0.77
Midline B3 serotonin nerves in rat medulla are involved in hypotensive effect of methyldopa. J Cardiovasc Pharmacol (1986) 0.77
Vasorelaxant properties of isolated human internal mammary arteries and saphenous veins: comparative effects of milrinone and sodium nitroprusside. J Cardiovasc Pharmacol (1993) 0.77
Topographic profile of reperfusion into MCA territory following endothelin-1-induced transient focal cerebral ischaemia. Neurosci Lett (1996) 0.77
Pharmacological characterisation of endothelium-dependent relaxation in human radial artery: comparison with internal thoracic artery. Cardiovasc Res (1999) 0.77
Estrogen effects on nitric oxide release. Hypertension (1997) 0.77
A comparison of calcium pentagastrin and TRH tests in screening for medullary carcinoma of the thyroid in MEN IIA. Clin Endocrinol (Oxf) (1990) 0.77
Renal artery stenosis managed by Palmaz stent insertion: technical and clinical outcome. J Hypertens (1995) 0.77
Does potassium channel opening contribute to endothelium-dependent relaxation in human internal thoracic artery? Clin Sci (Lond) (1999) 0.77