Published in Hypertension on July 01, 2001
Human cytomegalovirus infection of endothelial cells triggers platelet adhesion and aggregation. J Virol (2005) 1.19
Tropism-modification strategies for targeted gene delivery using adenoviral vectors. Viruses (2010) 1.17
Transcriptional targeting of tumor endothelial cells for gene therapy. Adv Drug Deliv Rev (2009) 0.91
Spinal cord injury reduces the efficacy of pseudorabies virus labeling of sympathetic preganglionic neurons. J Neuropathol Exp Neurol (2009) 0.89
New vectors and strategies for cardiovascular gene therapy. Curr Gene Ther (2007) 0.87
Construction of a novel expression cassette for increasing transgene expression in vivo in endothelial cells of large blood vessels. Gene Ther (2010) 0.84
CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma. Cancer Gene Ther (2009) 0.84
In vivo transcriptional targeting into the retinal vasculature using recombinant baculovirus carrying the human flt-1 promoter. Virol J (2007) 0.82
Specific micro RNA-regulated TetR-KRAB transcriptional control of transgene expression in viral vector-transduced cells. PLoS One (2012) 0.78
In vitro and in vivo analysis of expression cassettes designed for vascular gene transfer. Gene Ther (2007) 0.77
Allocation of patients to treatment groups in a controlled clinical study. Br J Cancer (1978) 5.25
Effect of renal-artery stenting on progression of renovascular renal failure. Lancet (1997) 3.89
On the use of Pocock and Simon's method for balancing treatment numbers over prognostic factors in the controlled clinical trial. Biometrics (1976) 3.82
Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells. Nat Med (2001) 3.81
An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism. J Virol (1998) 3.32
Glomerular hyperfiltration: a new marker of metabolic risk. Kidney Int (2007) 3.17
Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group. Oncogene (1990) 2.97
Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism. J Virol (1996) 2.52
Adenovirus type 5 fiber knob binds to MHC class I alpha2 domain at the surface of human epithelial and B lymphoblastoid cells. EMBO J (1997) 2.43
Statistical errors in papers in the British Journal of Psychiatry. Br J Psychiatry (1979) 2.38
Blood clearance rates of adenovirus type 5 in mice. J Gen Virol (2000) 2.36
Rapid, nonradioactive detection of mutations in the human genome by allele-specific amplification. J Lab Clin Med (1989) 2.22
Impaired macrophage phagocytosis in non-eosinophilic asthma. Clin Exp Allergy (2013) 2.21
Better blood pressure control: how to combine drugs. J Hum Hypertens (2003) 2.19
Targeted gene delivery by tropism-modified adenoviral vectors. Nat Biotechnol (1996) 2.14
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. Proc Natl Acad Sci U S A (1998) 2.11
Inadvertent esophageal intubation in the field: reliance on a fool's "gold standard". Acad Emerg Med (1997) 2.07
Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-kappa B. FEBS Lett (1998) 2.05
Localization of iodine-125-mIP-Des-Met14-bombesin (7-13)NH2 in ovarian carcinoma induced to express the gastrin releasing peptide receptor by adenoviral vector-mediated gene transfer. J Nucl Med (1997) 2.05
Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. Hypertension (2001) 1.97
Nine unknown rearrangements in 16p13.3 and 11p15.4 causing alpha- and beta-thalassaemia characterised by high resolution multiplex ligation-dependent probe amplification. J Med Genet (2005) 1.96
Inhibition of late vein graft neointima formation in human and porcine models by adenovirus-mediated overexpression of tissue inhibitor of metalloproteinase-3. Circulation (2000) 1.94
CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors. Gene Ther (2001) 1.92
High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles. Proc Natl Acad Sci U S A (1992) 1.90
Replicative adenoviruses for cancer therapy. Nat Biotechnol (2000) 1.89
Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob. J Virol (1998) 1.88
Targeted gene delivery of BMPR2 attenuates pulmonary hypertension. Eur Respir J (2011) 1.84
Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo. Nat Biotechnol (2001) 1.83
Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells. Cancer Res (1998) 1.83
Increased airway epithelial and T-cell apoptosis in COPD remains despite smoking cessation. Eur Respir J (2005) 1.72
Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. Proc Natl Acad Sci U S A (1992) 1.72
Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector. Nat Biotechnol (1997) 1.66
Families of patients with premature coronary heart disease: an obvious but neglected target for primary prevention. BMJ (2007) 1.63
Inhibition of transcription factor NF-kappaB reduces matrix metalloproteinase-1, -3 and -9 production by vascular smooth muscle cells. Cardiovasc Res (2001) 1.62
Characterization of infectivity of knob-modified adenoviral vectors in glioma. Cancer Biol Ther (2008) 1.61
Differential susceptibility of primary and established human glioma cells to adenovirus infection: targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer. Cancer Res (1998) 1.59
Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen presenting cells. Nat Biotechnol (1998) 1.59
Lesional overexpression of matrix metalloproteinase-9 promotes intraplaque hemorrhage in advanced lesions but not at earlier stages of atherogenesis. Arterioscler Thromb Vasc Biol (2005) 1.56
Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries. Circulation (2000) 1.54
The alpha 1-antitrypsin gene and its mutations. Clinical consequences and strategies for therapy. Chest (1989) 1.51
In vitro antibacterial properties of BRL 36650, a novel 6 alpha-substituted penicillin. Antimicrob Agents Chemother (1984) 1.50
MR of the brain using fluid-attenuated inversion recovery (FLAIR) pulse sequences. AJNR Am J Neuroradiol (1992) 1.49
Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells. Mol Ther (2001) 1.47
Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody. Gynecol Oncol (1995) 1.47
NMR detection of creatine kinase expressed in liver of transgenic mice: determination of free ADP levels. Proc Natl Acad Sci U S A (1990) 1.45
Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium. Hypertension (1999) 1.44
A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency. Clin Cancer Res (2001) 1.43
Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin. J Virol (2001) 1.43
Addition of a short peptide ligand to the adenovirus fiber protein. Gene Ther (1995) 1.42
Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide. Am J Physiol Heart Circ Physiol (2001) 1.41
The need for evaluation of gastroesophageal reflux in brain-damaged children referred for feeding gastrostomy. J Pediatr Surg (1981) 1.39
A system for the propagation of adenoviral vectors with genetically modified receptor specificities. Nat Biotechnol (1999) 1.39
RAS and FMS mutations following cytotoxic therapy for childhood acute lymphoblastic leukaemia. Leukemia (1995) 1.39
Adenoviral vector infection of the human exocrine pancreas. Arch Surg (1997) 1.38
Increased intracellular T helper 1 proinflammatory cytokine production in peripheral blood, bronchoalveolar lavage and intraepithelial T cells of COPD subjects. Clin Exp Immunol (2007) 1.38
The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily. Proc Natl Acad Sci U S A (1997) 1.36
Transductional targeting of adenovirus vectors for gene therapy. Cancer Gene Ther (2006) 1.34
Endothelial function in hypertension: the role of superoxide anion. Hypertension (1999) 1.33
Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells. J Virol (2000) 1.33
Characterization of a messenger RNA polynucleotide vaccine vector. Cancer Res (1995) 1.30
Promoters and control elements: designing expression cassettes for gene therapy. Curr Gene Ther (2004) 1.30
The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells. Eur J Cancer (2002) 1.29
Anticonvulsant drugs and cancer. A cohort study in patients with severe epilepsy. Lancet (1979) 1.27
Maturation of dendritic cells accompanies high-efficiency gene transfer by a CD40-targeted adenoviral vector. J Immunol (1999) 1.26
Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene. Ann Surg (1999) 1.25
Localization of the death domain of tissue inhibitor of metalloproteinase-3 to the N terminus. Metalloproteinase inhibition is associated with proapoptotic activity. J Biol Chem (2000) 1.25
Treatment of colorectal liver metastases by adenoviral transfer of tissue inhibitor of metalloproteinases-2 into the liver tissue. Cancer Res (2000) 1.23
Efficient oncolysis by a replicating adenovirus (ad) in vivo is critically dependent on tumor expression of primary ad receptors. Cancer Res (2001) 1.20
A Sindbis virus mRNA polynucleotide vector achieves prolonged and high level heterologous gene expression in vivo. Nucleic Acids Res (1995) 1.20
Adenovirus-mediated gene transfer of the human TIMP-1 gene inhibits smooth muscle cell migration and neointimal formation in human saphenous vein. Hum Gene Ther (1998) 1.20
Increased production of TGF-beta and apoptosis of T lymphocytes isolated from peripheral blood in COPD. Am J Physiol Lung Cell Mol Physiol (2003) 1.20
Copy number variation and mosaicism. Cytogenet Genome Res (2009) 1.20
Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus. Nat Genet (1997) 1.18
Decreased EXT expression and intracellular accumulation of heparan sulphate proteoglycan in osteochondromas and peripheral chondrosarcomas. J Pathol (2007) 1.17
Role of superoxide in the depressed nitric oxide production by the endothelium of genetically hypertensive rats. Hypertension (1995) 1.17
Characterization of mouse A33 antigen, a definitive marker for basolateral surfaces of intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol (2000) 1.17
A targetable, injectable adenoviral vector for selective gene delivery to pulmonary endothelium in vivo. Mol Ther (2000) 1.17
Azithromycin increases phagocytosis of apoptotic bronchial epithelial cells by alveolar macrophages. Eur Respir J (2006) 1.17
A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial. Clin Cancer Res (2000) 1.14
Imaging and tissue biodistribution of 99mTc-labeled adenovirus knob (serotype 5). Gene Ther (1998) 1.14
Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol (2000) 1.13
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells. Cancer Gene Ther (2010) 1.13
An automatic registration method for frameless stereotaxy, image guided surgery, and enhanced reality visualization. IEEE Trans Med Imaging (1996) 1.11
Fiber knob modifications overcome low, heterogeneous expression of the coxsackievirus-adenovirus receptor that limits adenovirus gene transfer and oncolysis for human rhabdomyosarcoma cells. Cancer Res (2001) 1.11
Bcl-2 and Bcl-XL serve an anti-inflammatory function in endothelial cells through inhibition of NF-kappaB. J Clin Invest (1999) 1.11
Predictive diagnosis of myotonic dystrophy with flanking microsatellite markers. J Med Genet (1991) 1.10
CTX, a Xenopus thymocyte receptor, defines a molecular family conserved throughout vertebrates. Eur J Immunol (1998) 1.10
Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapy. Gene Ther (2005) 1.10
An adenovirus with enhanced infectivity mediates molecular chemotherapy of ovarian cancer cells and allows imaging of gene expression. Mol Ther (2001) 1.10
Divergent regulation by growth factors and cytokines of 95 kDa and 72 kDa gelatinases and tissue inhibitors or metalloproteinases-1, -2, and -3 in rabbit aortic smooth muscle cells. Biochem J (1996) 1.10
Imaging ROMK1 inwardly rectifying ATP-sensitive K+ channel protein using atomic force microscopy. Proc Natl Acad Sci U S A (1996) 1.09
Serial brain MRI at 3-6 month intervals as a surrogate marker for Alzheimer's disease. Br J Radiol (2002) 1.09