Published in Eur J Biochem on February 01, 2000
The applications of the novel polymeric fluoropyrimidine F10 in cancer treatment: current evidence. Future Oncol (2016) 0.79
A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations. Nat Biotechnol (2001) 4.66
Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistry. Eur J Biochem (2000) 3.33
Quantification of the contribution of various steps to the control of mitochondrial respiration. J Biol Chem (1982) 2.92
The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump. Proc Natl Acad Sci U S A (1994) 2.71
The danger of metabolic pathways with turbo design. Trends Biochem Sci (1998) 2.66
Quantification of information transfer via cellular signal transduction pathways. FEBS Lett (1997) 2.33
Why cytoplasmic signalling proteins should be recruited to cell membranes. Trends Cell Biol (2000) 2.03
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein. Proc Natl Acad Sci U S A (1995) 2.00
An alternative PII protein in the regulation of glutamine synthetase in Escherichia coli. Mol Microbiol (1996) 1.97
Transcriptome meets metabolome: hierarchical and metabolic regulation of the glycolytic pathway. FEBS Lett (2001) 1.91
How enzymes can capture and transmit free energy from an oscillating electric field. Proc Natl Acad Sci U S A (1986) 1.78
Monoclonal antibody JSB-1 detects a highly conserved epitope on the P-glycoprotein associated with multi-drug-resistance. Int J Cancer (1988) 1.78
GlnK, a PII-homologue: structure reveals ATP binding site and indicates how the T-loops may be involved in molecular recognition. J Mol Biol (1998) 1.75
Modern theories of metabolic control and their applications (review). Biosci Rep (1984) 1.75
A minimal hypothesis for membrane-linked free-energy transduction. The role of independent, small coupling units. Biochim Biophys Acta (1984) 1.74
Glycolysis in bloodstream form Trypanosoma brucei can be understood in terms of the kinetics of the glycolytic enzymes. J Biol Chem (1997) 1.59
The use of lac-type promoters in control analysis. Eur J Biochem (1993) 1.56
The macroworld versus the microworld of biochemical regulation and control. Trends Biochem Sci (1995) 1.54
Movement of fatty acids, fatty acid analogues, and bile acids across phospholipid bilayers. Biochemistry (1993) 1.53
Acetaldehyde mediates the synchronization of sustained glycolytic oscillations in populations of yeast cells. Eur J Biochem (1996) 1.50
Structure and partitioning of bacterial DNA: determined by a balance of compaction and expansion forces? FEMS Microbiol Lett (1995) 1.48
Understanding glucose transport by the bacterial phosphoenolpyruvate:glycose phosphotransferase system on the basis of kinetic measurements in vitro. J Biol Chem (2000) 1.46
Sustained oscillations in free-energy state and hexose phosphates in yeast. Yeast (1996) 1.45
FnrP and NNR of Paracoccus denitrificans are both members of the FNR family of transcriptional activators but have distinct roles in respiratory adaptation in response to oxygen limitation. Mol Microbiol (1997) 1.44
Do P-glycoprotein and major vault protein (MVP/LRP) expression correlate with in vitro daunorubicin resistance in acute myeloid leukemia? Leukemia (1999) 1.44
The signal transduction function for oxidative phosphorylation is at least second order in ADP. J Biol Chem (1996) 1.43
Mutational analysis of the nor gene cluster which encodes nitric-oxide reductase from Paracoccus denitrificans. Eur J Biochem (1996) 1.39
Nitrite and nitric oxide reduction in Paracoccus denitrificans is under the control of NNR, a regulatory protein that belongs to the FNR family of transcriptional activators. FEBS Lett (1995) 1.37
Quantifying heterogeneity: flow cytometry of bacterial cultures. Antonie Van Leeuwenhoek (1992) 1.37
Can free energy be transduced from electric noise? Proc Natl Acad Sci U S A (1987) 1.36
What controls glycolysis in bloodstream form Trypanosoma brucei? J Biol Chem (1999) 1.35
The two opposing activities of adenylyl transferase reside in distinct homologous domains, with intramolecular signal transduction. EMBO J (1997) 1.35
Compartmentation protects trypanosomes from the dangerous design of glycolysis. Proc Natl Acad Sci U S A (2000) 1.34
Control theory of regulatory cascades. J Theor Biol (1991) 1.34
Sensitivity of human, murine, and rat cells to 5-fluorouracil and 5'-deoxy-5-fluorouridine in relation to drug-metabolizing enzymes. Cancer Res (1986) 1.33
The genes of the glutamine synthetase adenylylation cascade are not regulated by nitrogen in Escherichia coli. Mol Microbiol (1993) 1.32
Transduction of intracellular and intercellular dynamics in yeast glycolytic oscillations. Biophys J (2000) 1.29
How yeast cells synchronize their glycolytic oscillations: a perturbation analytic treatment. Biophys J (2000) 1.29
Magainin 2 amide and analogues. Antimicrobial activity, membrane depolarization and susceptibility to proteolysis. FEBS Lett (1989) 1.28
Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma. Cancer Chemother Pharmacol (1993) 1.27
Nitric oxide is a signal for NNR-mediated transcription activation in Paracoccus denitrificans. J Bacteriol (1999) 1.26
DNA supercoiling depends on the phosphorylation potential in Escherichia coli. Mol Microbiol (1996) 1.25
How do enzyme activities control metabolite concentrations? An additional theorem in the theory of metabolic control. Eur J Biochem (1984) 1.22
Correlation of multidrug resistance with decreased drug accumulation, altered subcellular drug distribution, and increased P-glycoprotein expression in cultured SW-1573 human lung tumor cells. Cancer Res (1989) 1.22
Autoamplification of a two-component regulatory system results in "learning" behavior. J Bacteriol (2001) 1.21
Energy-dependent processes involved in reduced drug accumulation in multidrug-resistant human lung cancer cell lines without P-glycoprotein expression. Cancer Res (1992) 1.21
An additional PII in Escherichia coli: a new regulatory protein in the glutamine synthetase cascade. FEMS Microbiol Lett (1995) 1.20
Excess capacity of H(+)-ATPase and inverse respiratory control in Escherichia coli. EMBO J (1993) 1.20
Around the growth phase transition S. cerevisiae's make-up favours sustained oscillations of intracellular metabolites. FEBS Lett (1993) 1.19
Intracellular glucose concentration in derepressed yeast cells consuming glucose is high enough to reduce the glucose transport rate by 50%. J Bacteriol (1998) 1.18
A metabolic control analysis of kinetic controls in ATP free energy metabolism in contracting skeletal muscle. Am J Physiol Cell Physiol (2000) 1.18
Induction by verapamil of a rapid increase in ATP consumption in multidrug-resistant tumor cells. FASEB J (1988) 1.16
Control of glycolytic dynamics by hexose transport in Saccharomyces cerevisiae. Biophys J (2001) 1.16
Bacteriorhodopsin in liposomes. II. Experimental evidence in support of a theoretical model. Biochim Biophys Acta (1979) 1.16
Kinetics of daunorubicin transport by P-glycoprotein of intact cancer cells. Eur J Biochem (1992) 1.15
Functional detection of MDR1/P170 and MRP/P190-mediated multidrug resistance in tumour cells by flow cytometry. Br J Cancer (1995) 1.14
Cytosolic triglycerides and oxidative stress in central obesity: the missing link between excessive atherosclerosis, endothelial dysfunction, and beta-cell failure? Atherosclerosis (2000) 1.12
Thermodynamic efficiency of microbial growth is low but optimal for maximal growth rate. Proc Natl Acad Sci U S A (1983) 1.12
The multidrug-resistance-reverser verapamil interferes with cellular P-glycoprotein-mediated pumping of daunorubicin as a non-competing substrate. Eur J Biochem (1994) 1.11
Thermodynamics of growth. Non-equilibrium thermodynamics of bacterial growth. The phenomenological and the mosaic approach. Biochim Biophys Acta (1982) 1.09
Quantitative determination of factors contributing to doxorubicin resistance in multidrug-resistant cells. J Natl Cancer Inst (1989) 1.09
Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells. Br J Cancer (1993) 1.08
Immunohistochemical detection of P-glycoprotein in human tumor cells with a low degree of drug resistance. Int J Cancer (1989) 1.08
Quality control of multidrug resistance assays in adult acute leukemia: correlation between assays for P-glycoprotein expression and activity. Blood (1996) 1.06
Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export. Br J Cancer (2000) 1.06
Yeast cells with a specific cellular make-up and an environment that removes acetaldehyde are prone to sustained glycolytic oscillations. FEBS Lett (1994) 1.06
Implications of macromolecular crowding for signal transduction and metabolite channeling. Proc Natl Acad Sci U S A (1998) 1.06
Simvastatin improves disturbed endothelial barrier function. Circulation (2000) 1.06
Energy buffering of DNA structure fails when Escherichia coli runs out of substrate. J Bacteriol (1995) 1.04
Cortisol is transported by the multidrug resistance gene product P-glycoprotein. Br J Cancer (1993) 1.03
Electric potentiation, cooperativity, and synergism of magainin peptides in protein-free liposomes. Biochemistry (1993) 1.02
The Escherichia coli signal transducers PII (GlnB) and GlnK form heterotrimers in vivo: fine tuning the nitrogen signal cascade. Proc Natl Acad Sci U S A (2000) 1.02
Control analysis of glycolytic oscillations. Biophys Chem (1996) 1.01
Branched-chain alpha-keto acid catabolism via the gene products of the bkd operon in Enterococcus faecalis: a new, secreted metabolite serving as a temporary redox sink. J Bacteriol (2000) 1.00
Contribution of glucose transport to the control of the glycolytic flux in Trypanosoma brucei. Proc Natl Acad Sci U S A (1999) 1.00
Control of frequency and amplitudes is shared by all enzymes in three models for yeast glycolytic oscillations. Biochim Biophys Acta (1996) 1.00
Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells. Biochem Pharmacol (1994) 1.00
Regulation of oxidative phosphorylation: the flexible respiratory network of Paracoccus denitrificans. J Bioenerg Biomembr (1995) 1.00
The role of 7-hydroxymethotrexate during methotrexate anti-cancer therapy. Cancer Lett (1980) 0.99
Mosaic protonic coupling hypothesis for free energy transduction. FEBS Lett (1984) 0.99
Phase I and pharmacokinetic studies of high-dose uridine intended for rescue from 5-fluorouracil toxicity. Cancer Res (1984) 0.99
Metabolic channelling and control of the flux. FEBS Lett (1993) 0.98
Glycolysis in P-glycoprotein-overexpressing human tumor cell lines. Effects of resistance-modifying agents. FEBS Lett (1989) 0.97
The polyoxyethylene castor oil Cremophor EL modifies multidrug resistance. Br J Cancer (1990) 0.97
Metabolic design: how to engineer a living cell to desired metabolite concentrations and fluxes. Biotechnol Bioeng (1998) 0.97
Transcription regulation of the nir gene cluster encoding nitrite reductase of Paracoccus denitrificans involves NNR and NirI, a novel type of membrane protein. Mol Microbiol (1999) 0.97
Metabolic control by pump slippage and proton leakage in 'delocalized' and more localized chemiosmotic energy-coupling schemes. Biochem Soc Trans (1983) 0.96
Pharmacokinetics of 5-fluorouracil assessed with a sensitive mass spectrometric method in patients on a dose escalation schedule. Cancer Res (1988) 0.95
Probing daunorubicin accumulation defects in non-P-glycoprotein expressing multidrug-resistant cell lines using digitonin. Int J Cancer (1992) 0.95
Increase of daunorubicin and vincristine accumulation in multidrug resistant human ovarian carcinoma cells by a monoclonal antibody reacting with P-glycoprotein. Biochem Pharmacol (1988) 0.94
Control by enzymes, coenzymes and conserved moieties. A generalisation of the connectivity theorem of metabolic control analysis. Eur J Biochem (1994) 0.94
Metabolic control analysis of glycolysis in trypanosomes as an approach to improve selectivity and effectiveness of drugs. Mol Biochem Parasitol (2000) 0.94
Redox interactions in cytochrome c oxidase: from the "neoclassical" toward "modern" models. Biophys J (1992) 0.94
Glucose and the ATP paradox in yeast. Biochem J (2000) 0.93
The sum of the control coefficients of all enzymes on the flux through a group-transfer pathway can be as high as two. Eur J Biochem (1993) 0.93
P-glycoprotein drug efflux pump involved in the mechanisms of intrinsic drug resistance in various colon cancer cell lines. Evidence for a saturation of active daunorubicin transport. Biochem Pharmacol (1991) 0.93
A critical appraisal of evidence for localized energy coupling. Kinetic studies on liposomes containing bacteriorhodopsin and ATP synthase. Biochem J (1985) 0.92