PubRank

H Ohgaki

Author PubWeight™ 106.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Primary and secondary glioblastomas: from concept to clinical diagnosis. Neuro Oncol 1999 4.25
2 Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol 1996 4.18
3 Tumors associated with p53 germline mutations: a synopsis of 91 families. Am J Pathol 1997 2.40
4 Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C --> A:T mutations of the TP53 tumor suppressor gene. Carcinogenesis 2001 1.71
5 Incidence and timing of p53 mutations during astrocytoma progression in patients with multiple biopsies. Clin Cancer Res 1997 1.71
6 Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection. Am J Pathol 1999 1.66
7 Loss of heterozygosity on chromosome 10 is more extensive in primary (de novo) than in secondary glioblastomas. Lab Invest 2000 1.59
8 Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis. Cancer Res 2001 1.58
9 Genetic profile of gliosarcomas. Am J Pathol 2000 1.57
10 Promoter hypermethylation of the RB1 gene in glioblastomas. Lab Invest 2001 1.54
11 Identification in human brain tumors of DNA sequences specific for SV40 large T antigen. Brain Pathol 1999 1.54
12 PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas. J Neuropathol Exp Neurol 1998 1.52
13 p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma. Cancer Res 1992 1.48
14 APC mutations in sporadic medulloblastomas. Am J Pathol 2000 1.40
15 Comparative study of p53 gene and protein alterations in human astrocytic tumors. J Neuropathol Exp Neurol 1993 1.39
16 More about: cell and molecular biology of simian virus 40: implications for human infections and disease. J Natl Cancer Inst 2000 1.39
17 Gene expression profiling of low-grade diffuse astrocytomas by cDNA arrays. Cancer Res 2000 1.35
18 Up-regulation of Fas (APO-1/CD95) ligand and down-regulation of Fas expression in human esophageal cancer. Cancer Res 1998 1.29
19 p14ARF deletion and methylation in genetic pathways to glioblastomas. Brain Pathol 2001 1.27
20 Demonstration of carcinogenicity in F344 rats of 2-amino-3-methyl-imidazo[4,5-f]quinoline from broiled sardine, fried beef and beef extract. Gan 1984 1.26
21 CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death. Oncogene 2003 1.26
22 Carcinogenicity in mice of a mutagenic compound, 2-amino-3-methylimidazo[4,5-f]quinoline, from broiled sardine, cooked beef and beef extract. Carcinogenesis 1984 1.24
23 Induction of lymphoma in CDF1 mice by the food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Jpn J Cancer Res 1989 1.23
24 Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas. Acta Neuropathol 1997 1.19
25 Determination of p53 mutations, EGFR overexpression, and loss of p16 expression in pediatric glioblastomas. J Neuropathol Exp Neurol 1997 1.19
26 Amplification and overexpression of MDM2 in primary (de novo) glioblastomas. J Neuropathol Exp Neurol 1997 1.14
27 Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qter. Am J Pathol 1999 1.11
28 Carcinogenicity in mice and rats of heterocyclic amines in cooked foods. Environ Health Perspect 1986 1.07
29 Carcinogenicity in mice of mutagenic compounds from a tryptophan pyrolyzate. Science 1981 1.06
30 Reduced expression of the Aalpha subunit of protein phosphatase 2A in human gliomas in the absence of mutations in the Aalpha and Abeta subunit genes. Int J Cancer 2001 1.06
31 Loss of heterozygosity on chromosome 19 in secondary glioblastomas. J Neuropathol Exp Neurol 2000 1.04
32 Carcinogenicity in rats of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline. Carcinogenesis 1988 1.04
33 Carcinogenicity in mice of mutagenic compounds from glutamic acid and soybean globulin pyrolysates. Carcinogenesis 1984 1.03
34 Necrogenesis and Fas/APO-1 (CD95) expression in primary (de novo) and secondary glioblastomas. J Neuropathol Exp Neurol 1998 1.03
35 Carcinogenicity in mice of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) from cooked foods. Carcinogenesis 1987 1.02
36 Genetic profile of the giant cell glioblastoma. Lab Invest 1999 1.02
37 PHF3-specific antibody responses in over 60% of patients with glioblastoma multiforme. Oncogene 2001 1.02
38 p53 mutations in primary human lung tumors and their metastases. Mol Carcinog 1994 1.02
39 Loss of DCC expression and glioma progression. Cancer Res 1997 1.01
40 Phenotype vs genotype in the evolution of astrocytic brain tumors. Toxicol Pathol 2000 1.00
41 Human astrocytic brain tumors express AP02L/TRAIL. Acta Neuropathol 1999 0.99
42 Carcinogenicity test of quercetin and rutin in golden hamsters by oral administration. Carcinogenesis 1982 0.98
43 Fas ligand expression in glioblastoma cell lines and primary astrocytic brain tumors. Brain Pathol 1997 0.98
44 Heterocyclic amines produced in cooked food: unavoidable xenobiotics. Princess Takamatsu Symp 1990 0.96
45 Induction of cancers in the intestine, liver and various other organs of rats by feeding mutagens from glutamic acid pyrolysate. Gan 1984 0.94
46 Concurrent inactivation of RB1 and TP53 pathways in anaplastic oligodendrogliomas. J Neuropathol Exp Neurol 2001 0.94
47 Astrocytomas and choroid plexus tumors in two families with identical p53 germline mutations. J Neuropathol Exp Neurol 1998 0.94
48 Expression of Fas/APO-1 during the progression of astrocytomas. Cancer Res 1995 0.94
49 Carcinomas of the renal pelvis associated with smoking and phenacetin abuse: p53 mutations and polymorphism of carcinogen-metabolising enzymes. Int J Cancer 1998 0.93
50 Infrequent alterations of the p15, p16, CDK4 and cyclin D1 genes in non-astrocytic human brain tumors. Int J Cancer 1996 0.93
51 p53 mutations versus EGF receptor expression in giant cell glioblastomas. J Neuropathol Exp Neurol 1997 0.92
52 Extracapsular spread of squamous cell carcinoma in neck lymph nodes: prognostic factor of laryngeal cancer. Laryngoscope 1991 0.91
53 Carcinogenicity in rats of the mutagenic compounds 1-nitropyrene and 3-nitrofluoranthene. Cancer Lett 1982 0.91
54 Induction of sarcomas in rats by subcutaneous injection of dinitropyrenes. Carcinogenesis 1984 0.91
55 BCL-xL: time-dependent dissociation between modulation of apoptosis and invasiveness in human malignant glioma cells. Cell Death Differ 2005 0.91
56 Promoter hypermethylation and homozygous deletion of the p14ARF and p16INK4a genes in oligodendrogliomas. Acta Neuropathol 2001 0.91
57 p53 and PTEN gene mutations in gemistocytic astrocytomas. Acta Neuropathol 1998 0.91
58 Activation of K-ras and oncogenes other than ras family in rat fibrosarcomas induced by 1,8-dinitropyrene. Cancer Lett 1985 0.89
59 Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity. Neuropathol Appl Neurobiol 2014 0.89
60 p53 protein accumulation and gene mutations in human glioma cell lines. Int J Cancer 1993 0.89
61 Demonstration by in situ hybridization of ret proto-oncogene mRNA in developing placenta during mid-term of rat gestation. Oncogene 1990 0.87
62 Role of gemistocytes in astrocytoma progression. Lab Invest 1997 0.87
63 p53 mutations in phenacetin-associated human urothelial carcinomas. Carcinogenesis 1993 0.86
64 Primitive neuroectodermal tumors after prophylactic central nervous system irradiation in children. Association with an activated K-ras gene. Cancer 1992 0.86
65 Absence of carcinogenicity of 1-nitropyrene, correction of previous results, and new demonstration of carcinogenicity of 1,6-dinitropyrene in rats. Cancer Lett 1985 0.85
66 Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma. Oncogene 2011 0.84
67 p53 knockout mice (-/-) are more susceptible than (+/-) or (+/+) mice to N-methyl-N-nitrosourea stomach carcinogenesis. Carcinogenesis 2000 0.84
68 Invasiveness in vitro and biological markers in human primary glioblastomas. J Neurooncol 2001 0.84
69 Combination effects of forty carcinogens administered at low doses to male rats. Jpn J Cancer Res 1989 0.84
70 Germline SDHD mutation in paraganglioma of the spinal cord. Oncogene 2001 0.84
71 Altered expression of hepatic carcinogen metabolizing enzymes with liver injury in HBV transgenic mouse lineages expressing various amounts of hepatitis B surface antigen. Liver 1999 0.83
72 APO2L/TRAIL expression in human brain tumors. Acta Neuropathol 2000 0.83
73 Molecular analysis of glioma and skin-tumour alterations in a xeroderma-pigmentosum child. Int J Cancer 1999 0.82
74 CD95 ligand: lethal weapon against malignant glioma? Brain Pathol 1998 0.82
75 Induction of hepatocellular carcinoma and highly metastatic squamous cell carcinomas in the forestomach of mice by feeding 2-amino-3,4-dimethylimidazo[4,5-f]quinoline. Carcinogenesis 1986 0.82
76 p53 gene mutations in oropharyngeal carcinomas: a comparison of solitary and multiple primary tumours and lymph-node metastases. Int J Cancer 1994 0.82
77 Induction of gastric carcinomas in nonhuman primates by N-ethyl-N'-nitro-N-nitrosoguanidine. J Natl Cancer Inst 1986 0.82
78 Absence of a synergistic effect between fumonisin B1 and N-nitrosomethylbenzylamine in the induction of oesophageal papillomas in the rat. Nat Toxins 1997 0.82
79 Induction of tumors in the Zymbal gland, oral cavity, colon, skin and mammary gland of F344 rats by a mutagenic compound, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline. Carcinogenesis 1989 0.82
80 p53 mutations in sweat gland carcinomas. Int J Cancer 1998 0.82
81 Genetic control of susceptibility of rats to gastric carcinoma. Cancer Res 1983 0.81
82 Preferential expression of Fas/APO1 (CD95) and apoptotic cell death in perinecrotic cells of glioblastoma multiforme. Acta Neuropathol 1996 0.81
83 Second primary glioblastoma. J Neuropathol Exp Neurol 2001 0.80
84 Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx. Princess Takamatsu Symp 1985 0.80
85 Laryngeal epithelial changes on effects of smoking and drinking. Auris Nasus Larynx 1990 0.80
86 Mutation analysis of hBUB1, hBUBR1 and hBUB3 genes in glioblastomas. Acta Neuropathol 2001 0.79
87 Genetic evidence of the neoplastic nature of gemistocytes in astrocytomas. Acta Neuropathol 2001 0.79
88 Aspects of intracranial and spinal tumors in patients with Down syndrome and report of a rapidly progressing Grade 2 astrocytoma. Cancer 2001 0.79
89 Mutagens and carcinogens in cooked food. Prog Clin Biol Res 1986 0.78
90 Genetic study of host factors in gastrocarcinogenesis in rats. IARC Sci Publ 1982 0.78
91 PCTAIRE3: a putative mediator of growth arrest and death induced by CTS-1, a dominant-positive p53-derived synthetic tumor suppressor, in human malignant glioma cells. Cancer Gene Ther 2006 0.78
92 Reduced expression of the P2 form of the gap junction protein connexin43 in malignant meningiomas. J Neuropathol Exp Neurol 1997 0.77
93 Modulation of N-nitrosomethylbenzylamine bioactivation by diallyl sulfide in vivo. Carcinogenesis 1992 0.77
94 Squamous cell carcinoma found in the cardiac region of the stomach of an aged orangoutang. Gan 1984 0.77
95 Direct DNA sequencing following SSCP analysis. Anal Biochem 1994 0.77
96 Active H-ras and N-ras in rat fibrosarcomas induced by 1,6-dinitropyrene. Cancer Lett 1987 0.77
97 DNA methylation in rat stomach and duodenum following chronic exposure to N-methyl-N'-nitro-N-nitrosoguanidine and the effect of dietary taurocholate. Carcinogenesis 1988 0.76
98 Carcinogenicity in rats of a mutagenic compound, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole, from tryptophan pyrolysate. Jpn J Cancer Res 1985 0.76
99 Genetic and environmental factors in the etiology of human brain tumors. Toxicol Lett 1995 0.76
100 Genetic alterations associated with glioma progression. Verh Dtsch Ges Pathol 1994 0.76
101 Early gastric cancer induced by N-ethyl-N'-nitro-N-nitrosoguanidine in a cynomolgus monkey six years after initial diagnosis of the lesion. Jpn J Cancer Res 1990 0.75
102 DNA adducts formed by the comutagens harman and norharman in various tissues of mice. Cancer Lett 1988 0.75
103 p53 mutations in oropharyngeal carcinomas: a comparison of solitary and multiple primary tumours and lymph node metastases. Verh Dtsch Ges Pathol 1994 0.75
104 [p53 mutation in phenacetin-induced urothelial carcinomas]. Verh Dtsch Ges Pathol 1993 0.75
105 Genetic control of sensitivity of rats to gastrocarcinogenesis by N-methyl-N'-nitro-N-nitrosoguanidine. IARC Sci Publ 1982 0.75
106 Liver cancer and precancerous changes in rats induced by the basic fraction of tryptophan pyrolysate. Cancer Lett 1981 0.75
107 Detoxifying potential of thioproline against N-nitroso compounds, N-nitrosodimethylamine and N-nitrosocimetidine. Cancer Lett 1990 0.75
108 Recently identified nitrite-reactive compounds in food: occurrence and biological properties of the nitrosated products. IARC Sci Publ 1987 0.75
109 Derivation of a murine monoclonal antibody useful for immunohistochemical diagnosis of human adenoid cystic carcinoma and stomach cancer. Jpn J Cancer Res 1987 0.75
110 Lung fibre burden in lung cancer cases employed in the rock and slag wool industry. Ann Occup Hyg 2005 0.75
111 Genetic polymorphisms and susceptibility to cancer development. Pharmacogenetics 1995 0.75
112 Entrapment by magnetic microcapsules of the protein pyrolysates IQ, PhIP and Glu-P-1, and alteration of IQ metabolite exposure within the rat gastrointestinal tract by risk-modulating components of the human diet. Carcinogenesis 1992 0.75
113 Type and frequency of p53 mutations in tumors of the nervous system and its coverings. Recent Results Cancer Res 1994 0.75
114 The inhibitory effect of thioproline on carcinogenesis induced by N-benzylmethylamine and nitrite. Food Chem Toxicol 1988 0.75
115 Fibrosarcoma of the neck in an adult female. Auris Nasus Larynx 1989 0.75
116 The operation of a superconducting wiggler at TERAS. J Synchrotron Radiat 1998 0.75
117 Carcinogenicity of dinitropyrenes in rats and hamsters. Dev Toxicol Environ Sci 1986 0.75
118 [Genetic factors in gastric carcinogenesis]. Gan To Kagaku Ryoho 1983 0.75
119 Study of the promoting effect of sodium chloride on gastric carcinogenesis by N-methyl-N'-nitro-N-nitrosoguanidine in inbred Wistar rats. Gan 1984 0.75
120 Sequential histologic changes during gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in susceptible ACI and resistant BUF rats. J Natl Cancer Inst 1986 0.75