Published in Am J Pathol on December 01, 1999
The Wnt signaling pathway and its role in tumor development. J Cancer Res Clin Oncol (2003) 3.06
Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma. Am J Pathol (2003) 2.42
Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes. Proc Natl Acad Sci U S A (2004) 2.30
Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis. Am J Pathol (2000) 2.18
The links between axin and carcinogenesis. J Clin Pathol (2005) 2.07
Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: frequent allelic loss on chromosome 11p and alterations in the APC/beta-catenin pathway. Am J Pathol (2002) 1.96
Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad. Semin Cancer Biol (2010) 1.91
Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration. Hepatology (2001) 1.71
Genetics of hepatocellular carcinoma. World J Gastroenterol (2007) 1.64
Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver. Gastroenterology (2005) 1.58
Role of Wnt/β-catenin signaling in liver metabolism and cancer. Int J Biochem Cell Biol (2009) 1.55
Targeted therapy for hepatocellular carcinoma: novel agents on the horizon. Oncotarget (2012) 1.55
Increased activation of the Wnt/β-catenin pathway in spontaneous hepatocellular carcinoma observed in farnesoid X receptor knockout mice. J Pharmacol Exp Ther (2011) 1.36
Wnt signaling in liver cancer. Curr Drug Targets (2008) 1.34
Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma. J Gastroenterol (2008) 1.25
β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis. Gastroenterology (2015) 1.20
The role of Hedgehog signaling in fibrogenic liver repair. Int J Biochem Cell Biol (2010) 1.18
Frizzled7 as an emerging target for cancer therapy. Cell Signal (2011) 1.16
Enhancement of canonical Wnt/β-catenin signaling activity by HCV core protein promotes cell growth of hepatocellular carcinoma cells. PLoS One (2011) 1.16
Hepatitis C virus NS5A-mediated activation of phosphoinositide 3-kinase results in stabilization of cellular beta-catenin and stimulation of beta-catenin-responsive transcription. J Virol (2005) 1.13
Loss of Wnt5a and Ror2 protein in hepatocellular carcinoma associated with poor prognosis. World J Gastroenterol (2012) 1.10
Alcoholic liver disease and hepatitis C: a frequently underestimated combination. World J Gastroenterol (2009) 1.08
Hepatitis C-associated hepatocellular carcinomas in non-cirrhotic livers. Mod Pathol (2009) 0.99
Histopathology of hepatocellular carcinoma. World J Gastroenterol (2014) 0.98
HCV tumor promoting effect is dependent on host genetic background. PLoS One (2009) 0.95
Dickkopfs and Wnt/β-catenin signalling in liver cancer. World J Clin Oncol (2011) 0.94
Expression of beta-catenin in hepatocellular carcinoma. World J Gastroenterol (2005) 0.94
Upregulation of the Wnt co-receptor LRP6 promotes hepatocarcinogenesis and enhances cell invasion. PLoS One (2012) 0.92
Frequent beta-catenin mutations in juvenile nasopharyngeal angiofibromas. Am J Pathol (2001) 0.92
Pegylated interferon alpha targets Wnt signaling by inducing nuclear export of β-catenin. J Hepatol (2010) 0.90
Methylation status of c-fms oncogene in HCC and its relationship with clinical pathology. World J Gastroenterol (2001) 0.90
The Wnt/β-catenin signaling pathway in liver biology and disease. Expert Rev Gastroenterol Hepatol (2010) 0.90
Molecular alterations in hepatocellular carcinoma associated with hepatitis B and hepatitis C infections. Oncotarget (2016) 0.88
Molecular mechanisms underlying hepatocellular carcinoma. Viruses (2009) 0.87
Profiling of exome mutations associated with progression of HBV-related hepatocellular carcinoma. PLoS One (2014) 0.86
Cytoplasmic and/or nuclear expression of β-catenin correlate with poor prognosis and unfavorable clinicopathological factors in hepatocellular carcinoma: a meta-analysis. PLoS One (2014) 0.85
Immunobiology of hepatocellular carcinoma. Langenbecks Arch Surg (2011) 0.84
Molecular signalling in hepatocellular carcinoma: Role of and crosstalk among WNT/ß-catenin, Sonic Hedgehog, Notch and Dickkopf-1. Can J Gastroenterol Hepatol (2015) 0.82
Targeting protein arginine methyltransferase 5 inhibits human hepatocellular carcinoma growth via the downregulation of beta-catenin. J Transl Med (2015) 0.81
Hepatitis C virus-related hepatocellular carcinoma: An insight into molecular mechanisms and therapeutic strategies. World J Hepatol (2012) 0.81
Molecular mechanism of iron metabolism and overload in chronic hepatitis C. J Gastroenterol (2007) 0.81
DNA markers in molecular diagnostics for hepatocellular carcinoma. Expert Rev Mol Diagn (2014) 0.80
Molecularly targeted therapy for advanced hepatocellular carcinoma - a drug development crisis? World J Gastrointest Oncol (2016) 0.80
Effect of mutant β-catenin on liver growth homeostasis and hepatocarcinogenesis in transgenic mice. Liver Int (2011) 0.79
A peculiar mutation spectrum emerging from young peruvian patients with hepatocellular carcinoma. PLoS One (2014) 0.78
Correlation of exon 3 β-catenin mutations with glutamine synthetase staining patterns in hepatocellular adenoma and hepatocellular carcinoma. Mod Pathol (2016) 0.77
B cells in chronically hepatitis C virus-infected individuals lack a virus-induced mutation signature in the TP53, CTNNB1, and BCL6 genes. J Virol (2012) 0.76
Aberrant regulation of Wnt signaling in hepatocellular carcinoma. World J Gastroenterol (2016) 0.76
Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma. Oncotarget (2016) 0.76
Pathway Analyses Identify Novel Variants in the WNT Signaling Pathway Associated with Tuberculosis in Chinese Population. Sci Rep (2016) 0.76
c-Myc and transforming growth factor α enhance the development of hepatic lesions due to mutant β-catenin in transgenic mice. Comp Med (2014) 0.75
Liver cancer with concomitant TP53 and CTNNB1 mutations: a case report. BMC Clin Pathol (2016) 0.75
Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma. J Gastroenterol (2016) 0.75
Identification of the β-catenin/JNK/prothymosin-alpha axis as a novel target of sorafenib in hepatocellular carcinoma cells. Oncotarget (2015) 0.75
Wnt-/-β-catenin pathway signaling in human hepatocellular carcinoma. World J Hepatol (2015) 0.75
Frequent somatic TERT promoter mutations and CTNNB1 mutations in hepatocellular carcinoma. Oncotarget (2016) 0.75
Selective Retention of an Inactive Allele of the DKK2 Tumor Suppressor Gene in Hepatocellular Carcinoma. PLoS Genet (2016) 0.75
The Recent Advances on Liver Cancer Stem Cells: Biomarkers, Separation, and Therapy. Anal Cell Pathol (Amst) (2017) 0.75
Lessons from hereditary colorectal cancer. Cell (1996) 25.73
Functional interaction of beta-catenin with the transcription factor LEF-1. Nature (1996) 15.88
beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J (1997) 12.97
Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly. Science (1996) 9.12
Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc Natl Acad Sci U S A (1995) 7.31
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. Cancer Res (1998) 5.80
Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum Mol Genet (1992) 5.14
Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci U S A (1998) 4.99
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC. Nat Genet (1997) 4.86
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med (1998) 4.48
Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. Am J Pathol (1998) 4.43
Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin. J Biol Chem (1997) 4.28
Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol (1996) 4.18
Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients. Proc Natl Acad Sci U S A (1992) 4.13
A common human skin tumour is caused by activating mutations in beta-catenin. Nat Genet (1999) 3.93
The oncogenic activation of beta-catenin. Curr Opin Genet Dev (1999) 3.87
Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. Proc Natl Acad Sci U S A (1994) 3.76
Beta-catenin: a key mediator of Wnt signaling. Curr Opin Genet Dev (1998) 3.65
Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways. Curr Opin Cell Biol (1997) 3.52
Hepatitis C and hepatocellular carcinoma. Hepatology (1997) 2.83
Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors. Cancer Res (1994) 2.61
Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res (1998) 2.42
Beta-catenin mutations in human prostate cancer. Cancer Res (1998) 2.37
Sporadic medulloblastomas contain oncogenic beta-catenin mutations. Cancer Res (1998) 2.33
Beta-catenin mutation in carcinoma of the uterine endometrium. Cancer Res (1998) 2.27
Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. Cancer Res (1999) 2.18
Beta-catenin mutations are more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas. Cancer Res (1999) 2.09
Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. J Virol (1996) 2.02
Activation of the beta-catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without adenomatous polyposis coli mutations. Cancer Res (1998) 2.02
Mutations in the beta-catenin gene (CTNNB1) in endometrioid ovarian carcinomas. Cancer Res (1998) 2.01
Hepatocellular carcinoma: from gene to public health. J Natl Cancer Inst (1997) 1.86
Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma. Cancer Res (1999) 1.86
The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas. Int J Cancer (1997) 1.64
Amplification and overexpression of the cyclin D1 gene in aggressive human hepatocellular carcinoma. Cancer Res (1994) 1.63
Hepatitis B viruses and hepatocellular carcinoma. Adv Cancer Res (1992) 1.62
Allelotype study of primary hepatocellular carcinoma. Cancer Res (1991) 1.61
APC gene: database of germline and somatic mutations in human tumors and cell lines. Nucleic Acids Res (1998) 1.57
Frequent somatic mutations of the APC gene in human pancreatic cancer. Cancer Res (1992) 1.55
Transcriptional repression of p53 promoter by hepatitis C virus core protein. J Biol Chem (1997) 1.54
Suppression of apoptotic cell death by hepatitis C virus core protein. Virology (1996) 1.46
Amplification of the c-myc gene in human hepatocellular carcinoma: biologic significance. J Formos Med Assoc (1993) 1.15
Pathogenesis of hepatitis B and C-induced hepatocellular carcinoma. J Viral Hepat (1998) 1.10
Loss of constitutional heterozygosity on chromosome 5q in hepatocellular carcinoma without cirrhosis. Br J Cancer (1991) 1.10
Hepatitis C virus infection as a major risk factor for hepatocellular carcinoma. J Hepatol (1996) 1.08
Clonal analysis of regenerative nodules in hepatitis C virus-induced liver cirrhosis. Gastroenterology (1994) 0.96
p53 gene mutation spectrum in hepatocellular carcinomas in Hong Kong Chinese. Oncogene (1994) 0.95
Frequent beta-catenin abnormalities in bone and soft-tissue tumors. Jpn J Cancer Res (1999) 0.93
Multiple hepatocellular carcinomas at the early stage have different clonality. Gastroenterology (1993) 0.91
Molecular mechanism of hepatocarcinogenesis. J Gastroenterol Hepatol (1997) 0.91
Hepatitis B and C viruses and primary liver cancer. Baillieres Clin Gastroenterol (1996) 0.87
The putative tumor suppressor gene on chromosome 5q for hepatocellular carcinoma is distinct from the MCC and APC genes. Cancer Detect Prev (1993) 0.84
Excess risk of colon cancer associated with a polymorphism of the APC gene? Cancer Res (1998) 0.82
Clonality in hepatocellular carcinoma: analysis of methylation pattern of polymorphic X-chromosome-linked phosphoglycerate kinase gene in females. Hepatology (1995) 0.81
Hepatocellular carcinoma and hepatitis B virus infection: molecular evidence for monoclonal origin and expansion of malignantly transformed hepatocytes. J Cancer Res Clin Oncol (1987) 0.79
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol (2000) 9.85
A family of cAMP-binding proteins that directly activate Rap1. Science (1998) 6.12
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Mol Cell (2000) 5.92
PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes (2001) 5.18
Spatio-temporal images of growth-factor-induced activation of Ras and Rap1. Nature (2001) 4.83
Primary and secondary glioblastomas: from concept to clinical diagnosis. Neuro Oncol (1999) 4.25
Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol (1996) 4.18
Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos. Nature (1996) 3.79
Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box. Nature (1989) 3.74
The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas. Cancer (1999) 3.47
Transmission of human herpesvirus 8 infection from renal-transplant donors to recipients. N Engl J Med (1998) 3.21
Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression. J Biol Chem (2000) 2.97
Specificity of DNase I. Estimation of nucleosides present at the 5'-phosphate terminus of a limit digest of DNA by DNase I. J Biochem (1966) 2.96
Helicobacter pylori and symptomatic relapse of gastro-oesophageal reflux disease: a randomised controlled trial. Lancet (2001) 2.88
Phospholipase C assay using p-nitrophenylphosphoryl-choline together with sorbitol and its application to studying the metal and detergent requirement of the enzyme. Anal Biochem (1976) 2.87
Activation of Rac1 by a Crk SH3-binding protein, DOCK180. Genes Dev (1998) 2.82
Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study. Diabetologia (2003) 2.80
Human immunodeficiency virus vpr gene encodes a virion-associated protein. AIDS Res Hum Retroviruses (1990) 2.67
Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits. Science (1994) 2.65
Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein. J Virol (1990) 2.60
Self-assembled B19 parvovirus capsids, produced in a baculovirus system, are antigenically and immunogenically similar to native virions. Proc Natl Acad Sci U S A (1991) 2.55
A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia. Proc Natl Acad Sci U S A (1998) 2.47
DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol Cell Biol (1996) 2.44
A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors. Cell (1992) 2.43
cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt). Mol Cell Biol (1996) 2.42
Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 gene. Cancer Res (2001) 2.41
Tumors associated with p53 germline mutations: a synopsis of 91 families. Am J Pathol (1997) 2.40
Preoperative identification of meningiomas that are highly likely to recur. J Neurosurg (1999) 2.38
Tumor necrosis factor-alpha (TNF-alpha) plays a protective role in acute viralmyocarditis in mice: A study using mice lacking TNF-alpha. Circulation (2001) 2.36
Molecular cloning and functional characterization of the receptor for Clostridium perfringens enterotoxin. J Cell Biol (1997) 2.25
Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i) Nature (1999) 2.23
Human immunodeficiency virus type 1 has an additional coding sequence in the central region of the genome. Proc Natl Acad Sci U S A (1988) 2.20
Induction of coronary artery spasm by acetylcholine in patients with variant angina: possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm. Circulation (1986) 2.17
Acute Wernicke's encephalopathy: comparison of magnetic resonance images and autopsy findings. Intern Med (1996) 2.14
The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse. Genes Dev (1995) 2.11
The long-term effects of polymethylmethacrylate contact lens wear on the corneal endothelium. Ophthalmology (1994) 2.05
The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo. Genes Dev (2001) 2.04
Radio-guided sentinel node detection for gastric cancer. Br J Surg (2002) 1.97
Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma. Cancer Res (1993) 1.95
Corneal endothelial changes in type I and type II diabetes mellitus. Am J Ophthalmol (1984) 1.94
Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia. Cancer Res (2001) 1.93
Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo. J Biol Chem (1997) 1.91
Magnetic resonance imaging of biological specimens by electron paramagnetic resonance of nitroxide spin labels. Science (1985) 1.85
CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis. Cancer Res (1999) 1.82
Abnormal plasminogen. A hereditary molecular abnormality found in a patient with recurrent thrombosis. J Clin Invest (1978) 1.79
Enhanced expression of vascular endothelial growth factor in human pancreatic cancer correlates with local disease progression. Clin Cancer Res (1997) 1.74
Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis. EMBO J (2001) 1.74
Isolation and purification of two antigenically active, "complimentary" polypeptide fragments of tetanus neurotoxin. Infect Immun (1975) 1.74
Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity. J Biol Chem (2000) 1.73
Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man. Diabetologia (1994) 1.73
Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex. J Biol Chem (1998) 1.72
Fatal hepatoxicity secondary to nimesulide. Eur J Clin Pharmacol (2001) 1.72
Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C --> A:T mutations of the TP53 tumor suppressor gene. Carcinogenesis (2001) 1.71
Incidence and timing of p53 mutations during astrocytoma progression in patients with multiple biopsies. Clin Cancer Res (1997) 1.71
Purification of a yeast TATA box-binding protein that exhibits human transcription factor IID activity. Proc Natl Acad Sci U S A (1989) 1.70
Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis. Mol Cell Biol (1996) 1.69
Recent dioxin contamination from Agent Orange in residents of a southern Vietnam city. J Occup Environ Med (2001) 1.68
Noncontact, two-dimensional measurement of retinal microcirculation using laser speckle phenomenon. Invest Ophthalmol Vis Sci (1994) 1.67
Efficient enzymatic hydrolysis of polyprenyl pyrophosphates. Biochim Biophys Acta (1982) 1.65
Targeted and highly efficient gene transfer into CD4+ cells by a recombinant human immunodeficiency virus retroviral vector. J Clin Invest (1991) 1.64
Prenatal diagnosis of fetal cytomegalovirus infection. Am J Obstet Gynecol (1991) 1.62
Nonrandom distribution of gp120 N-linked glycosylation sites important for infectivity of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1992) 1.61
Hormone-induced morphogenesis and growth: role of mesenchymal-epithelial interactions. Recent Prog Horm Res (1983) 1.60
International prognostic scoring system and TP53 mutations are independent prognostic indicators for patients with myelodysplastic syndrome. Br J Haematol (2001) 1.59
Loss of heterozygosity on chromosome 10 is more extensive in primary (de novo) than in secondary glioblastomas. Lab Invest (2000) 1.59
Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters. Mol Cell Biol (1990) 1.58
Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis. Cancer Res (2001) 1.58
Genetic profile of gliosarcomas. Am J Pathol (2000) 1.57
Mast cells promote lung vascular remodelling in pulmonary hypertension. Eur Respir J (2010) 1.57
Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects treated with pioglitazone. Diabetes Care (2001) 1.56
Gene expression profiling of exercise-induced cardiac hypertrophy in rats. Acta Physiol Scand (2005) 1.55
Bromocriptine: a novel approach to the treatment of type 2 diabetes. Diabetes Care (2000) 1.55
Promoter hypermethylation of the RB1 gene in glioblastomas. Lab Invest (2001) 1.54
Identification in human brain tumors of DNA sequences specific for SV40 large T antigen. Brain Pathol (1999) 1.54
Non-invasive assessment of cardiac output during exercise in healthy young humans: comparison between Modelflow method and Doppler echocardiography method. Acta Physiol Scand (2003) 1.54
Characterization of neutrophil NADPH oxidase factors p47-phox and p67-phox from recombinant baculoviruses. J Biol Chem (1991) 1.54
TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP. Oncogene (2011) 1.53
European consensus on the histopathology of inflammatory bowel disease. J Crohns Colitis (2013) 1.53
Genetic progression and divergence in pancreatic carcinoma. Am J Pathol (2000) 1.53
PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas. J Neuropathol Exp Neurol (1998) 1.52
Role of aminopeptidase N (CD13) in tumor-cell invasion and extracellular matrix degradation. Int J Cancer (1993) 1.52
Lipopolysaccharide induction of indoleamine 2,3-dioxygenase is mediated dominantly by an IFN-gamma-independent mechanism. Eur J Immunol (2001) 1.51
Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene. Involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer. J Biol Chem (1999) 1.50
Cytomegalovirus infection and graft rejection in renal transplantation. Transplantation (2001) 1.50
Human biliary epithelial cells secrete and respond to cytokines and hepatocyte growth factors in vitro: interleukin-6, hepatocyte growth factor and epidermal growth factor promote DNA synthesis in vitro. Hepatology (1994) 1.49
In vivo evaluation of NM441, a new thiazeto-quinoline derivative. Antimicrob Agents Chemother (1991) 1.49
System for the investigation of the bacteriophage-directed synthesis of diphtherial toxin. J Bacteriol (1967) 1.49
18F-FDG PET detection of colonic adenomas. J Nucl Med (2001) 1.49
Sjögren's syndrome complicated with autoimmune hepatitis and antiphospholipid antibody syndrome. Intern Med (2000) 1.49
Effect of rosiglitazone on glucose and non-esterified fatty acid metabolism in Type II diabetic patients. Diabetologia (2001) 1.48
p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma. Cancer Res (1992) 1.48
Intestinal fatty acid-binding protein is a useful diagnostic marker for mesenteric infarction in humans. Gastroenterology (1996) 1.48
Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide. Immunol Lett (1994) 1.47
Progressive and sufficient decrease of hepatitis B core antibody can predict the disappearance of hepatitis B virus DNA in Japanese patients with hepatitis B surface antigen clearance. J Gastroenterol (2000) 1.47
Real-time measurement of human optic nerve head and choroid circulation, using the laser speckle phenomenon. Jpn J Ophthalmol (1997) 1.47
Heritable artificial sex chromosomes in the medaka, Oryzias latipes. Heredity (Edinb) (2009) 1.46
Swine influenza virus strains recognize sialylsugar chains containing the molecular species of sialic acid predominantly present in the swine tracheal epithelium. FEBS Lett (1997) 1.46
Molecular study of eight Japanese cases of glucose-6-phosphate dehydrogenase deficiency by nonradioisotopic single-strand conformation polymorphism analysis. Blood (1994) 1.46
Colonic mast cells in controls and slow transit constipation patients. Aliment Pharmacol Ther (2011) 1.46
The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway. Proc Natl Acad Sci U S A (1998) 1.46