Published in J Epidemiol Community Health on November 01, 1999
Coffee, pancreatic cancer and the question of causation. J Epidemiol Community Health (2000) 2.92
Cigarette smoking accelerates progression of alcoholic chronic pancreatitis. Gut (2005) 2.38
The Pine River statement: human health consequences of DDT use. Environ Health Perspect (2009) 2.15
ras Mutations and a cup of coffee: cause, confounder, effect modifier, or what else? J Epidemiol Community Health (1999) 2.04
Frequency of K-ras mutations in pancreatic intraductal neoplasias associated with pancreatic ductal adenocarcinoma and chronic pancreatitis: a meta-analysis. Neoplasia (2005) 2.03
Clinical relevance of KRAS in human cancers. J Biomed Biotechnol (2010) 1.34
K-ras mutation and p16 and preproenkephalin promoter hypermethylation in plasma DNA of pancreatic cancer patients: in relation to cigarette smoking. Pancreas (2007) 1.10
Food and nutrient intakes and K-ras mutations in exocrine pancreatic cancer. J Epidemiol Community Health (2007) 0.86
Validity of the hospital discharge diagnosis in epidemiologic studies of biliopancreatic pathology. PANKRAS II Study Group. Eur J Epidemiol (2000) 0.83
Family history of cancer and germline BRCA2 mutations in sporadic exocrine pancreatic cancer. Gut (2002) 0.83
Exposures, mutations and the history of causality. J Epidemiol Community Health (2001) 0.82
Timing of blood extraction in epidemiologic and proteomic studies: results and proposals from the PANKRAS II Study. Eur J Epidemiol (2007) 0.81
Estimating dietary intakes from a brief questionnaire: A simulation study of reliability in a molecular epidemiologic study of pancreatic and biliary diseases. Eur J Epidemiol (2006) 0.76
Coffee, K-ras mutations and pancreatic cancer: a heterogeneous aetiology or an artefact? J Epidemiol Community Health (2000) 0.76
CYP1B1 polymorphisms and k-ras mutations in patients with pancreatic ductal adenocarcinoma. Dig Dis Sci (2008) 0.76
Non-hierarchical logistic models and case-only designs for assessing susceptibility in population-based case-control studies. Stat Med (1994) 6.50
Tumor-suppressive pathways in pancreatic carcinoma. Cancer Res (1997) 4.54
p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma. Cancer Res (1997) 2.88
Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease. Gastroenterology (1996) 2.59
Tests for trend and dose response: misinterpretations and alternatives. Am J Epidemiol (1992) 2.51
Statistical analysis of molecular epidemiology studies employing case-series. Cancer Epidemiol Biomarkers Prev (1994) 2.26
Dietary and nutritional factors and pancreatic cancer: a case-control study based on direct interviews. J Natl Cancer Inst (1998) 1.91
Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer. Int J Cancer (1994) 1.82
Oncogenes and their applications in epidemiologic studies. Am J Epidemiol (1989) 1.68
p53-null cells are more sensitive to ultraviolet light only in the presence of caffeine. Cancer Res (1996) 1.54
Life-style risk factors for pancreatic cancer in Louisiana: a case-control study. Am J Epidemiol (1988) 1.54
Reliability of information on cigarette smoking and beverage consumption provided by hospital controls. Epidemiology (1996) 1.46
Incorporating biomarkers into cancer epidemiology: a matrix of biomarker and study design categories. Cancer Epidemiol Biomarkers Prev (1995) 1.41
Occurrence, trends and environment etiology of pancreatic cancer. Scand J Work Environ Health (1998) 1.38
A prospective study of K-ras mutations in the plasma of pancreatic cancer patients. Clin Cancer Res (1998) 1.36
K-ras mutation and pancreatic adenocarcinoma. Int J Pancreatol (1995) 1.35
Caffeine intake and delayed conception: a European multicenter study on infertility and subfecundity. European Study Group on Infertility Subfecundity. Am J Epidemiol (1997) 1.33
Cell cycle regulation in response to DNA damage in mammalian cells: a historical perspective. Cancer Metastasis Rev (1995) 1.26
Vitamin D receptors and anti-proliferative effects of vitamin D derivatives in human pancreatic carcinoma cells in vivo and in vitro. Br J Cancer (1997) 1.25
Smoking, alcohol, coffee, and tea intake and incidence of cancer of the exocrine pancreas: the Iowa Women's Health Study. Cancer Epidemiol Biomarkers Prev (1997) 1.22
Chromosome changes caused by alterations of p53 expression. Mutat Res (1996) 1.22
K-ras mutation in focal proliferative lesions of human pancreas. Cancer Epidemiol Biomarkers Prev (1998) 1.16
Self-report reliability and symptomatology of habitual caffeine consumption. Br J Clin Pharmacol (1989) 1.08
Epidemiology of and risk factors for pancreatic cancer. Surg Clin North Am (1995) 1.08
Nutrition and pancreatic cancer. Cancer Causes Control (1996) 1.03
Ki-ras mutations in exocrine pancreatic cancer: association with clinico-pathological characteristics and with tobacco and alcohol consumption. PANK-ras I Project Investigators. Int J Cancer (1997) 1.02
Measurement of coffee and caffeine intake: implications for epidemiologic research. Prev Med (1988) 1.01
Confounders contributing to the reported associations of coffee or caffeine with disease. Prev Med (1988) 0.99
Dose-response relationship between coffee and the risk of pancreas cancer. Jpn J Clin Oncol (1996) 0.96
Learning from case reports: diagnostic issues in an epidemiologic study of pancreatic cancer. J Clin Epidemiol (1998) 0.95
Causal thinking, biomarkers, and mechanisms of carcinogenesis. J Clin Epidemiol (1996) 0.94
Validity of self-reports of caffeine use. J Clin Pharmacol (1991) 0.91
Consumption of methylxanthine-containing beverages and risk of pancreatic cancer. Cancer Lett (1990) 0.91
Coffee and cancer of the pancreas: an Italian multicenter study. Pancreas (1995) 0.90
Caffeine inhibits gene-specific repair of UV-induced DNA damage in hamster cells and in human xeroderma pigmentosum group C cells. Carcinogenesis (1995) 0.90
Coffee consumption and the risk of cancer of the exocrine pancreas: a case-control study in a low-risk population. Epidemiology (1992) 0.89
Expression of apoptosis-related oncoproteins and modulation of apoptosis by caffeine in human leukemic cells. J Cancer Res Clin Oncol (1995) 0.89
Human cancer, carcinogenic exposures and mutation spectra. Mutat Res (1999) 0.89
Tobacco smoke inhalation pattern, tobacco type, and bladder cancer in Spain. Am J Epidemiol (1991) 0.89
Ki-ras mutations as a prognostic factor in extrahepatic bile system cancer. PANK-ras I Project Investigators. J Clin Oncol (1995) 0.87
Comet assay studies indicate that caffeine-mediated increase in radiation risk of embryos is due to inhibition of DNA repair. Mutagenesis (1996) 0.86
DDT and pancreatic cancer. J Natl Cancer Inst (1993) 0.85
Bladder cancer and coffee consumption in smokers and non-smokers in Spain. Int J Epidemiol (1993) 0.85
Re: Detection of c-Ki-ras mutation by PCR/RFLP analysis and diagnosis of pancreatic adenocarcinomas. J Natl Cancer Inst (1994) 0.84
Liver dysfunction related to hepatitis B and C in patients with inflammatory bowel disease treated with immunosuppressive therapy. Gut (2010) 2.98
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4. Virchows Arch (2001) 2.73
Vectorial targeting of apical and basolateral plasma membrane proteins in a human adenocarcinoma epithelial cell line. Proc Natl Acad Sci U S A (1989) 2.36
Incidence of collagenous and lymphocytic colitis: a 5-year population-based study. Am J Gastroenterol (1999) 2.32
Comparison of heparin and steroids in the treatment of moderate and severe ulcerative colitis. Gastroenterology (2000) 2.22
Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma. J Natl Cancer Inst (1991) 2.19
Anti-Hu antibodies in patients with small-cell lung cancer: association with complete response to therapy and improved survival. J Clin Oncol (1997) 2.19
Terminal cancer. duration and prediction of survival time. Eur J Cancer (2000) 2.13
Incomplete overlapping of biological, clinical, and environmental information in molecular epidemiological studies: a variety of causes and a cascade of consequences. J Epidemiol Community Health (2002) 2.13
[The use of human gamma globulin in the treatment of common variable immunodeficiency]. Med Clin (Barc) (1995) 2.04
Inferring ancestral origin using a single multiplex assay of ancestry-informative marker SNPs. Forensic Sci Int Genet (2007) 2.03
Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancer. Gut (2005) 1.87
Improving strategies for detecting genetic patterns of disease susceptibility in association studies. Stat Med (2008) 1.86
Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer. Int J Cancer (1994) 1.82
MUC6 apomucin shows a distinct normal tissue distribution that correlates with Lewis antigen expression in the human stomach. Gastroenterology (1995) 1.75
Randomized phase III study of gemcitabine-cisplatin versus etoposide-cisplatin in the treatment of locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol (1999) 1.74
Visceral leishmaniasis: another HIV-associated opportunistic infection? Report of eight cases and review of the literature. AIDS (1991) 1.74
Myofibroblast proliferation, fibrosis, and defective pancreatic repair induced by cyclosporin in rats. Gut (1999) 1.66
Phenotypic heterogeneity of melanoma. Relation to the differentiation program of melanoma cells. J Exp Med (1987) 1.65
Basic molecular genetics for epidemiologists. J Epidemiol Community Health (2003) 1.62
Late Crohn's disease patients present an increase in peripheral Th17 cells and cytokine production compared with early patients. Aliment Pharmacol Ther (2009) 1.62
Expression of epidermal growth factor receptor in human cultured cells and tissues: relationship to cell lineage and stage of differentiation. Cancer Res (1986) 1.60
Derangement of mucosal barrier function by bacteria colonizing the rat colonic mucosa. Eur J Clin Invest (1998) 1.60
Risk of a first community-acquired spontaneous bacterial peritonitis in cirrhotics with low ascitic fluid protein levels. Gastroenterology (1999) 1.59
Induction of chronic pancreatic disease by trinitrobenzene sulfonic acid infusion into rat pancreatic ducts. Pancreas (1996) 1.59
Patients with achalasia lack nitric oxide synthase in the gastro-oesophageal junction. Eur J Clin Invest (1993) 1.57
VCAM-1, but not ICAM-1 or MAdCAM-1, immunoblockade ameliorates DSS-induced colitis in mice. Lab Invest (2000) 1.54
A brief dementia screener suitable for use by non-specialists in resource poor settings--the cross-cultural derivation and validation of the brief Community Screening Instrument for Dementia. Int J Geriatr Psychiatry (2010) 1.53
Typing of mitochondrial DNA coding region SNPs of forensic and anthropological interest using SNaPshot minisequencing. Forensic Sci Int (2004) 1.52
Diagnostic certainty and potential for misclassification in exocrine pancreatic cancer. PANKRAS I Project Investigations. J Clin Epidemiol (1994) 1.50
Class 1 (unique) tumor antigens of human melanoma. Identification of a 90,000 dalton cell surface glycoprotein by autologous antibody. J Exp Med (1984) 1.48
Role of Helicobacter pylori in stomach cancer after partial gastrectomy for benign ulcer disease. Rev Esp Enferm Dig (2005) 1.47
Role of intestinal microflora in chronic inflammation and ulceration of the rat colon. Gut (1994) 1.47
Influence of dose-rate on inflammatory damage and adhesion molecule expression after abdominal radiation in the rat. Int J Radiat Oncol Biol Phys (1999) 1.46
Parosteal osteoma of the iliac bone. Skeletal Radiol (1998) 1.44
[CD4+ lymphocytes in patients with a Leishmania-HIV coinfection]. Med Clin (Barc) (1995) 1.41
Influence of "diagnostic delay" upon cancer survival: an analysis of five tumour sites. J Epidemiol Community Health (1991) 1.41
Differential expression of the human mucin genes MUC1 to MUC5 in relation to growth and differentiation of different mucus-secreting HT-29 cell subpopulations. J Cell Sci (1993) 1.40
Pseudomitochondrial genome haunts disease studies. J Med Genet (2008) 1.40
A multicenter, randomized, double-blind study comparing once-daily bedtime administration of famotidine and ranitidine in the short-term treatment of active duodenal ulcer. Hepatogastroenterology (1989) 1.39
[Extrabronchial small-cell carcinoma: apropos 6 cases]. Med Clin (Barc) (1993) 1.39
[Thrombocytopenia onset in acute episodes of pancreatitis]. Med Clin (Barc) (1995) 1.38
Occurrence, trends and environment etiology of pancreatic cancer. Scand J Work Environ Health (1998) 1.38
A multicenter, randomized, double-blind study comparing a daily bedtime administration of famotidine and ranitidine in short-term treatment of active duodenal ulcer. Digestion (1989) 1.38
Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer. Proc Natl Acad Sci U S A (2006) 1.36
Differentiation antigens of melanocytes and melanoma: analysis of melanosome and cell surface markers of human pigmented cells with monoclonal antibodies. J Invest Dermatol (1988) 1.34
Dietary fish oil reduces progression of chronic inflammatory lesions in a rat model of granulomatous colitis. Gut (1990) 1.34
Altered expression of MUC2, MUC4, and MUC5 mucin genes in pancreas tissues and cancer cell lines. Gastroenterology (1994) 1.34
Nuclear PARP-1 protein overexpression is associated with poor overall survival in early breast cancer. Ann Oncol (2011) 1.33
Occupation and bladder cancer in a hospital-based case-control study in Spain. Occup Environ Med (2007) 1.32
Normal human pancreas cultures display functional ductal characteristics. Lab Invest (1994) 1.29
Characterization of a mucin cDNA clone isolated from HT-29 mucus-secreting cells. The 3' end of MUC5AC? J Biol Chem (1995) 1.29
Comparison of predictive models, clinical criteria and molecular tumour screening for the identification of patients with Lynch syndrome in a population-based cohort of colorectal cancer patients. J Med Genet (2008) 1.28
Quantitative analysis of antibody localization in human metastatic colon cancer: a phase I study of monoclonal antibody A33. J Clin Oncol (1990) 1.28
Preliminary observations on the effect of recombinant leukocyte A interferon in homosexual men with Kaposi's sarcoma. N Engl J Med (1983) 1.26
Cancer survival and the duration of symptoms. An analysis of possible forms of the risk function. ISDS II Project Investigators. Eur J Cancer (1994) 1.25
Biomarkers of exposure to polycyclic aromatic hydrocarbons from environmental air pollution. Occup Environ Med (2004) 1.25
Surface antigens of melanomas and melanocytes defined by mouse monoclonal antibodies: specificity analysis and comparison of antigen expression in cultured cells and tissues. Cancer Res (1985) 1.24
Artificial recombination in forensic mtDNA population databases. Int J Legal Med (2004) 1.24
Randomized phase III study of 3-weekly versus weekly docetaxel in pretreated advanced non-small-cell lung cancer: a Spanish Lung Cancer Group trial. Ann Oncol (2005) 1.21
Stimulation of transforming growth factor beta1 by enteric bacteria in the pathogenesis of rat intestinal fibrosis. Gastroenterology (1998) 1.20
Intermediate filaments as differentiation markers of normal pancreas and pancreas cancer. Am J Pathol (1992) 1.20
Kinetic and mechanical basis of rolling through an integrin and novel Ca2+-dependent rolling and Mg2+-dependent firm adhesion modalities for the alpha 4 beta 7-MAdCAM-1 interaction. Biochemistry (2001) 1.20
Incrimination of anaerobic bacteria in the induction of experimental colitis. Am J Physiol (1997) 1.20
Coding region mitochondrial DNA SNPs: targeting East Asian and Native American haplogroups. Forensic Sci Int Genet (2006) 1.19
Differential apomucin expression in normal and neoplastic human gastrointestinal tissues. Gastroenterology (1994) 1.18
A bidirectional corridor in the Sahel-Sudan belt and the distinctive features of the Chad Basin populations: a history revealed by the mitochondrial DNA genome. Ann Hum Genet (2007) 1.18
Immunological variables as predictors of prognosis in patients with Kaposi's sarcoma and the acquired immunodeficiency syndrome. Cancer Res (1986) 1.17
Participation of thromboxane and other eicosanoid synthesis in the course of experimental inflammatory colitis. Gastroenterology (1990) 1.16
Assessment of lifetime exposure to trihalomethanes through different routes. Occup Environ Med (2006) 1.15
Listeria monocytogenes bacteremia in the acquired immunodeficiency syndrome. Ann Intern Med (1984) 1.14
In situ hybridization shows distinct patterns of mucin gene expression in normal, benign, and malignant pancreas tissues. Gastroenterology (1995) 1.13
Cisplatin plus gemcitabine versus a cisplatin-based triplet versus nonplatinum sequential doublets in advanced non-small-cell lung cancer: a Spanish Lung Cancer Group phase III randomized trial. J Clin Oncol (2003) 1.11
Resolving relationship tests that show ambiguous STR results using autosomal SNPs as supplementary markers. Forensic Sci Int Genet (2008) 1.11
Activation of nuclear factor-kappa B is linked to resistance to neoadjuvant chemotherapy in breast cancer patients. Endocr Relat Cancer (2006) 1.11
Serum concentrations of organochlorine compounds and K-ras mutations in exocrine pancreatic cancer. PANKRAS II Study Group. Lancet (2000) 1.11