E Gherardi

Author PubWeight™ 66.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 1987 6.26
2 Scatter factor/hepatocyte growth factor is essential for liver development. Nature 1995 5.91
3 An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues. J Mol Biol 1996 3.15
4 Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase. Trends Cell Biol 1998 3.05
5 Structural repertoire of the human VH segments. J Mol Biol 1992 2.06
6 The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 beta-lactamase. J Mol Biol 1999 2.00
7 Original and artificial antibodies. Nature 1992 1.97
8 Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros. J Cell Biol 1995 1.79
9 Hepatocytes and scatter factor. Nature 1990 1.77
10 Heparan sulfate-modified CD44 promotes hepatocyte growth factor/scatter factor-induced signal transduction through the receptor tyrosine kinase c-Met. J Biol Chem 1999 1.58
11 Regulation of cell movement: the motogenic cytokines. Biochim Biophys Acta 1991 1.53
12 Mutation and selection during the secondary response to 2-phenyloxazolone. Proc Natl Acad Sci U S A 1991 1.35
13 Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP). Protein Sci 1994 1.29
14 Epithelial scatter factor and development of the chick embryonic axis. Development 1990 1.28
15 Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor. EMBO J 2001 1.28
16 The structural repertoire of the human V kappa domain. EMBO J 1995 1.26
17 Involvement of hepatocyte growth factor/scatter factor and met receptor signaling in hair follicle morphogenesis and cycling. FASEB J 2000 1.26
18 A role for HGF/SF in neural induction and its expression in Hensen's node during gastrulation. Development 1995 1.25
19 Non-random features of the repertoire expressed by the members of one V kappa gene family and of the V-J recombination. Eur J Immunol 1992 1.15
20 Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding. Nat Struct Biol 1999 1.14
21 Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains. J Mol Biol 2007 1.12
22 Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo. Curr Biol 1998 1.10
23 Co-expression of the HGF/SF and c-met genes during early mouse embryogenesis precedes reciprocal expression in adjacent tissues during organogenesis. Dev Genet 1996 1.07
24 Patients' perception of public, voluntary and private dispensaries in rural areas of Tanzania. East Afr Med J 1996 1.04
25 Characterization of the scatter factor/hepatocyte growth factor gene promoter. Positive and negative regulatory elements direct gene expression to mesenchymal cells. J Biol Chem 1995 0.96
26 Expression of HGF/SF, HGF1/MSP, and c-met suggests new functions during early chick development. Dev Genet 1995 0.92
27 Factors affecting epithelial interactions. Ciba Found Symp 1987 0.90
28 Colony assays for antibody fragments expressed in bacteria. J Immunol Methods 1991 0.87
29 Scatter factor and other regulators of cell mobility. Br Med Bull 1989 0.87
30 Signalling by HGF/SF and Met: the role of heparan sulphate co-receptors. Biochem Soc Trans 2006 0.87
31 Universal cloning and direct sequencing of rearranged antibody V genes using C region primers, biotin-captured cDNA and one-side PCR. J Immunol Methods 1995 0.85
32 Expression of a Cx43 deletion mutant in 3T3 A31 fibroblasts prevents PDGF-induced inhibition of cell communication and suppresses cell growth. Exp Cell Res 1999 0.83
33 HGF/SF inhibits junctional communication. Exp Cell Res 1995 0.81
34 Topography of apolipoprotein B in subcellular fractions of rabbit liver probed with a panel of monoclonal antibodies. J Lipid Res 1993 0.80
35 Insights into the structure of hepatocyte growth factor/scatter factor (HGF/SF) and implications for receptor activation. FEBS Lett 1998 0.80
36 Determination of the intracellular distribution and pool sizes of apolipoprotein B in rabbit liver. Biochem J 1992 0.80
37 Relationship among the concentrations of serum lipoproteins and changes in their chemical composition in patients with untreated nephrotic syndrome. Eur J Clin Invest 1977 0.79
38 Experimental nephrotic syndrome induced in the rat by puromycin aminonucleoside: hepatic synthesis of neutral lipids and phospholipids from 3H-water and 3H-palmitate. Lipids 1980 0.79
39 Chemical and morphological changes of rat plasma lipoproteins after a prolonged administration of diets containing olive oil and cholesterol. Atherosclerosis 1977 0.79
40 A sensitive RNase protection assay for the quantitation of the mRNAs for the LDL receptor and HMG-CoA reductase in human total RNA. Effects of treatments on cells in culture designed to up- and down-regulate expression of the LDL receptor. Atherosclerosis 1991 0.78
41 Experimental nephrotic syndrome in the rat induced by puromycin aminonucleoside: hepatic synthesis of lipoproteins and apolipoproteins. Lipids 1980 0.78
42 Down-regulation of scatter factor in MRC 5 fibroblasts by epithelial-derived cells. A model for scatter factor modulation. J Cell Sci 1992 0.78
43 Plasma and urine lipoproteins during the development of nephrotic syndrome induced in the rat by adriamycin. Exp Mol Pathol 1983 0.77
44 Transforming growth factor-beta 1 and interleukin-1 beta stimulate LDL receptor activity in Hep G2 cells. Atherosclerosis 1992 0.77
45 Dimerization of Fab fragments enables ready screening of phage antibodies that affect hepatocyte growth factor/scatter factor activity on target cells. Eur J Immunol 1997 0.77
46 Non-random features of the repertoire expressed by the members of one V kappa gene family and of the V-J recombination. Eur J Immunol 1992 0.77
47 Plasma and urinary lipids and lipoproteins during the development of nephrotic syndrome induced in the rat by puromycin aminonucleoside. Biochim Biophys Acta 1982 0.76
48 Membrane-bound apolipoprotein B is exposed at the cytosolic surface of liver microsomes. FEBS Lett 1992 0.76
49 Measurement of the absolute number of functioning low-density lipoprotein receptors in vivo using a monoclonal antibody. Biochem J 1995 0.75
50 Experimental nephrotic syndrome in the rat induced by puromycin aminonucleoside. Plasma and urinary lipoproteins. Exp Mol Pathol 1980 0.75
51 Capabilities of public, voluntary and private dispensaries in basic health service provision. World Health Forum 1996 0.75
52 Microcirculation and hemorheology in NIDDM patients. Angiology 1990 0.75
53 Topography of apolipoprotein B in subcellular fractions from rabbit liver. Biochem Soc Trans 1993 0.75
54 Secretion of lipoproteins, apolipoprotein A-I and apolipoprotein E by isolated and perfused liver of rat with experimental nephrotic syndrome. Biochim Biophys Acta 1981 0.75
55 The distribution of apolipoprotein B in endoplasmic reticulum and Golgi subfractions of rabbit liver. Biochem Soc Trans 1990 0.75
56 Porcine smooth muscle cell-conditioned medium stimulates LDL receptor activity in Hep G2 cells. J Cell Sci 1992 0.75