Probing the hydrophobic pocket of farnesyltransferase: aromatic substitution of CAAX peptidomimetics leads to highly potent inhibitors.

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Published in Bioorg Med Chem on December 01, 1999

Authors

Y Qian1, J J Marugan, R D Fossum, A Vogt, S M Sebti, A D Hamilton

Author Affiliations

1: Department of Chemistry, Yale University, New Haven, CT 06511, USA.

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