M A Buendia

Author PubWeight™ 49.19‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci U S A 1998 4.99
2 Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumours. Nature 1990 2.61
3 Transcription of woodchuck hepatitis virus in the chronically infected liver. EMBO J 1985 2.49
4 In vitro and in vivo synthesis of the hepatitis B virus surface antigen and of the receptor for polymerized human serum albumin from recombinant human adenoviruses. EMBO J 1985 2.18
5 Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferation. Am J Pathol 1999 1.87
6 The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice. Oncogene 1997 1.81
7 Activation of c-myc by woodchuck hepatitis virus insertion in hepatocellular carcinoma. Cell 1988 1.58
8 Comprehensive allelotyping of human hepatocellular carcinoma. Oncogene 1997 1.52
9 Hepadnavirus integration: mechanisms of activation of the N-myc2 retrotransposon in woodchuck liver tumors. J Virol 1992 1.34
10 Fused transcripts of c-myc and a new cellular locus, hcr in a primary liver tumor. Oncogene 1989 1.33
11 p53-independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro. Oncogene 1998 1.27
12 A new hepadnavirus endemic in arctic ground squirrels in Alaska. J Virol 1996 1.26
13 Rearrangement and enhanced expression of c-myc in hepatocellular carcinoma of hepatitis virus infected woodchucks. Nature 1987 1.25
14 Evidence for long-range oncogene activation by hepadnavirus insertion. EMBO J 1994 1.13
15 Activation of beta-catenin in epithelial and mesenchymal hepatoblastomas. Oncogene 2000 1.11
16 The HNF1/HNF4-dependent We2 element of woodchuck hepatitis virus controls viral replication and can activate the N-myc2 promoter. J Virol 1996 1.10
17 Hepatitis B virus. Sci Am 1991 1.07
18 Pro-apoptotic effect of the hepatitis B virus X gene. Biomed Pharmacother 1998 1.06
19 Wnt signaling and hepatocarcinogenesis: the hepatoblastoma model. Int J Biochem Cell Biol 2009 1.05
20 Identification of three distinct regions of allelic deletions on the short arm of chromosome 8 in hepatocellular carcinoma. Oncogene 1999 1.04
21 Liver-specific expression and high oncogenic efficiency of a c-myc transgene activated by woodchuck hepatitis virus insertion. Oncogene 1994 1.02
22 Frequent amplification of c-myc in ground squirrel liver tumors associated with past or ongoing infection with a hepadnavirus. Proc Natl Acad Sci U S A 1992 0.99
23 Hepatocellular carcinoma in WHV/N-myc2 transgenic mice: oncogenic mutations of beta-catenin and synergistic effect of p53 null alleles. Oncogene 2000 0.91
24 Woodchuck hepatitis virus enhancer I and enhancer II are both involved in N-myc2 activation in woodchuck liver tumors. J Virol 1998 0.87
25 Expression of the woodchuck N-myc2 retroposon in brain and in liver tumors is driven by a cryptic N-myc promoter. Mol Cell Biol 1992 0.85
26 Structure and expression of hcr, a locus rearranged with c-myc in a woodchuck hepatocellular carcinoma. Oncogene 1989 0.82
27 Nucleotide sequence of the woodchuck N-myc gene (WN-myc1). Nucleic Acids Res 1990 0.82
28 Preliminary results of interferon-alpha therapy on woodchuck hepatitis virus-induced hepatocarcinogenesis: possible benefit in female transgenic mice. J Hepatol 2001 0.81
29 Hepatocarcinogenesis in woodchuck hepatitis virus/c-myc mice: sustained cell proliferation and biphasic activation of insulin-like growth factor II. Hepatology 1997 0.81
30 Hepadna virus integration generates virus-cell cotranscripts carrying 3' truncated X genes in human and woodchuck liver tumors. J Med Virol 1995 0.81
31 Nucleotide sequence of the woodchuck hepatitis virus surface antigen mRNAs and the variability of three overlapping viral genes. Gene 1986 0.80
32 Cellular and viral trans-acting factors modulate N-myc2 promoter activity in woodchuck liver tumors. Oncogene 1997 0.80
33 Characterization of a large genomic size Moloney murine sarcoma virus produced by a transformed rat cell line. J Gen Virol 1982 0.79
34 Integration of hepatitis virus DNA near c-myc in woodchuck hepatocellular carcinoma. Gastroenterol Jpn 1990 0.79
35 Multiple rearrangements and activated expression of c-myc induced by woodchuck hepatitis virus integration in a primary liver tumour. Res Virol 1992 0.78
36 Analysis of integrated ground squirrel hepatitis virus and flanking host DNA in two hepatocellular carcinomas. J Virol 1994 0.77
37 [Hepatitis B virus and hepatocellular carcinoma]. Bull Acad Natl Med 1998 0.77
38 Unusual activation of the integrated preS1 promoter of woodchuck hepatitis virus in a liver tumour. J Gen Virol 1996 0.77
39 Studies of genetic defects in hepatocellular carcinoma: recent outcomes and new challenges. J Hepatol 2000 0.76
40 Functional analysis of ground squirrel hepatitis virus enhancer II. J Virol 1998 0.75
41 Evolutionary conservation of target sequences for cis-acting regulation in c-myc exon 1 and its upstream region. Gene 1990 0.75
42 A functional N-myc2 retroposon in ground squirrels: implications for hepadnavirus-associated carcinogenesis. Oncogene 1996 0.75
43 [Hepatitis B virus and hepatocellular carcinoma]. Ann Gastroenterol Hepatol (Paris) 1991 0.75
44 Infection of WHV/c-myc transgenic mice with Moloney murine leukaemia virus and proviral insertion near the syndecan-4 gene in an early liver tumour. Res Virol 1998 0.75
45 [Hepatitis B virus and hepatocellular carcinoma]. Bull Acad Natl Med 1991 0.75
46 [Efficacy of interferon alpha in primary prevention of preneoplastic lesions in a transgenic murine model of hepatocellular carcinoma related to the interaction between woodchuck hepatitis viruses and c-myc oncogene]. Gastroenterol Clin Biol 1997 0.75