O Landt

Author PubWeight™ 65.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reaction. Euro Surveill 2012 7.96
2 Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections. Euro Surveill 2012 4.95
3 Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet 2000 4.83
4 Improved strategies for sequence-independent amplification and sequencing of viral double-stranded RNA genomes. J Gen Virol 2009 2.58
5 Preexistence and evolution of imatinib mesylate-resistant clones in chronic myelogenous leukemia detected by a PNA-based PCR clamping technique. Ann Hematol 2003 2.01
6 Different real-time PCR formats compared for the quantitative detection of human cytomegalovirus DNA. Clin Chem 1999 1.77
7 Molecular diagnosis of a familial nonhemolytic hyperbilirubinemia (Gilbert's syndrome) in healthy subjects. Hepatology 2000 1.74
8 Apoptotic cells overexpress vinculin and induce vinculin-specific cytotoxic T-cell cross-priming. Nat Med 2001 1.66
9 Detection of influenza A(H1N1)v virus by real-time RT-PCR. Euro Surveill 2009 1.50
10 Peptide nucleic acid-mediated PCR clamping as a useful supplement in the determination of microbial diversity. Appl Environ Microbiol 2000 1.47
11 Keratin 8 Y54H and G62C mutations are not associated with inflammatory bowel disease. Dig Liver Dis 2004 1.45
12 Specific detection by real-time reverse-transcription PCR assays of a novel avian influenza A(H7N9) strain associated with human spillover infections in China. Euro Surveill 2013 1.44
13 Highly sensitive and specific fluorescence reverse transcription-PCR assay for the pseudogene-free detection of beta-actin transcripts as quantitative reference. Clin Chem 1999 1.35
14 Human herpesvirus 6A DNA Is detected frequently in plasma but rarely in peripheral blood leukocytes of patients after bone marrow transplantation. J Infect Dis 2000 1.34
15 LightCycler technology for the quantitation of bcr/abl fusion transcripts. Cancer Res 1999 1.27
16 Detection of human cytomegalovirus DNA by real-time quantitative PCR. J Clin Microbiol 2000 1.24
17 Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal. Nat Biotechnol 2000 1.10
18 Quantification of human cells in NOD/SCID mice by duplex real-time polymerase-chain reaction. Haematologica 2001 1.08
19 Two-round rapid-cycle RT-PCR in single closed capillaries increases the sensitivity of HCV RNA detection and avoids amplicon carry-over. J Clin Virol 2002 1.02
20 Rapid and sensitive typing of NPM1 mutations using LNA-mediated PCR clamping. Leukemia 2006 1.01
21 Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis. Aliment Pharmacol Ther 2007 1.00
22 Secondary structure and temperature-induced unfolding and refolding of ribonuclease T1 in aqueous solution. A Fourier transform infrared spectroscopic study. J Mol Biol 1993 0.95
23 LightCycler PCR assay for simultaneous detection of the H63D and S65C mutations in the HFE hemochromatosis gene based on opposite melting temperature shifts. Clin Chem 1999 0.95
24 Rapid screening and sensitive detection of NPM1 (nucleophosmin) exon 12 mutations in acute myeloid leukaemia. Leuk Res 2007 0.95
25 Relation of an interleukin-23 receptor gene polymorphism to graft-versus-host disease after hematopoietic-cell transplantation. Bone Marrow Transplant 2008 0.94
26 The importance of gene dosage studies: mutational analysis of the parkin gene in early-onset parkinsonism. Hum Mol Genet 2001 0.93
27 Stability and folding kinetics of ribonuclease T1 are strongly altered by the replacement of cis-proline 39 with alanine. J Mol Biol 1993 0.92
28 Identification of N-acetyltransferase 2 genotypes by continuous monitoring of fluorogenic hybridization probes. Anal Biochem 1999 0.89
29 Rapid quantification and differentiation of human polyomavirus DNA in undiluted urine from patients after bone marrow transplantation. J Clin Microbiol 2000 0.88
30 Two types of aggression are differentially related to serotonergic activity and the A779C TPH polymorphism. Behav Neurosci 2005 0.88
31 Exon deletions in the GCHI gene in two of four Turkish families with dopa-responsive dystonia. Neurology 2002 0.87
32 Polymorphisms of UDP-glucuronosyltransferase 1A7 are not involved in pancreatic diseases. J Med Genet 2005 0.86
33 Potential of LightCycler technology for quantification of minimal residual disease in childhood acute lymphoblastic leukemia. Leukemia 2000 0.86
34 Three alternatively spliced variants of the gene coding for the human bone morphogenetic protein-1. J Mol Med (Berl) 1998 0.83
35 Indicator plates for rapid detection of ribonuclease T1 secreting Escherichia coli clones. Nucleic Acids Res 1989 0.82
36 Peptide nucleic acid-mediated polymerase chain reaction clamping allows allelic allocation of CYP1A1 mutations. Anal Biochem 1997 0.82
37 Genotyping of the PXR A11156C polymorphism with locked nucleic acid containing fluorogenic probes. Pharmacogenomics J 2005 0.82
38 Role of the Cys 2-Cys 10 disulfide bond for the structure, stability, and folding kinetics of ribonuclease T1. Protein Sci 1994 0.81
39 Absence of association between SPINK1 trypsin inhibitor mutations and Type 1 or 2 diabetes mellitus in India and Germany. Diabetologia 2003 0.81
40 The significance of C3435T point mutation of the MDR1 gene in endometrial cancer. Int J Gynecol Cancer 2007 0.81
41 Keratin 8 Y54H and G62C mutations are not associated with liver disease. J Med Genet 2004 0.81
42 Rapid identification of minor histocompatibility antigen HA-1 subtypes H and R using fluorescence-labeled oligonucleotides. Tissue Antigens 2000 0.80
43 Peptide design aided by neural networks: biological activity of artificial signal peptidase I cleavage sites. Biochemistry 1998 0.79
44 The role of a trans-proline in the folding mechanism of ribonuclease T1. Eur J Biochem 1996 0.78
45 Trp59 to Tyr substitution enhances the catalytic activity of RNase T1 and of the Tyr to Trp variants in positions 24, 42 and 45. Protein Eng 1993 0.78
46 DNA microarray-chip based diagnosis of Q-fever (Coxiella burnetii). Clin Microbiol Infect 2009 0.77
47 Rapid detection of the Wilson's disease H1069Q mutation by melting curve analysis with the LightCycler. Clin Chem Lab Med 2001 0.77
48 Crystal structure of the Tyr45Trp mutant of ribonuclease T1 in a complex with 2'-adenylic acid. Eur J Biochem 1991 0.77
49 Fluorogenic probes to detect the A(-444)C transversion in the leukotriene C4 synthase promoter. Clin Chem 2000 0.75
50 UGT1A7 polymorphisms in chronic pancreatitis: an example of genotyping pitfalls. Pharmacogenomics J 2007 0.75
51 Extended kinetic analysis of ribonuclease T1 variants leads to an improved scheme for the reaction mechanism. Biochem Biophys Res Commun 1994 0.75
52 RNase T1 mutant Glu46Gln binds the inhibitors 2'GMP and 2'AMP at the 3' subsite. J Mol Biol 1992 0.75
53 Inhibition of neomycin phosphorotransferase expression in Entamoeba histolytica with antisense peptide nucleic acid (PNA) oligomers. Arch Med Res 2000 0.75