Published in Am J Pathol on March 01, 2000
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc Natl Acad Sci U S A (2001) 7.99
Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis. Am J Pathol (2003) 4.31
Beta-catenin--a linchpin in colorectal carcinogenesis? Am J Pathol (2002) 2.18
Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation. J Cell Biol (2001) 2.09
Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: frequent allelic loss on chromosome 11p and alterations in the APC/beta-catenin pathway. Am J Pathol (2002) 1.96
The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation. Am J Pathol (2001) 1.73
Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration. Hepatology (2001) 1.71
Patterning and nuclear beta-catenin expression in the colonic adenoma-carcinoma sequence. Analogies with embryonic gastrulation. Am J Pathol (2000) 1.56
β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis. Gut (2011) 1.40
Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells. Nat Commun (2013) 1.34
Beta-catenin dysregulation in thyroid neoplasms: down-regulation, aberrant nuclear expression, and CTNNB1 exon 3 mutations are markers for aggressive tumor phenotypes and poor prognosis. Am J Pathol (2001) 1.28
In vivo selection for metastasis promoting genes in the mouse. Proc Natl Acad Sci U S A (2007) 1.20
Crosstalk between tumor cells and microenvironment via Wnt pathway in colorectal cancer dissemination. World J Gastroenterol (2008) 1.18
Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas. Am J Pathol (2002) 1.14
Differential diagnosis of gastrointestinal stromal tumor and other spindle cell tumors in the gastrointestinal tract based on immunohistochemical analysis. Virchows Arch (2004) 1.13
The role of MUC1 and MUC3 in the biology and prognosis of colorectal cancer. World J Surg Oncol (2007) 1.11
Loss of myeloid cell-derived vascular endothelial growth factor accelerates fibrosis. Proc Natl Acad Sci U S A (2010) 1.03
MicroRNA-200a suppresses the Wnt/β-catenin signaling pathway by interacting with β-catenin. Int J Oncol (2011) 0.98
OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer. Mol Cancer (2014) 0.94
Somatic acquisition of TGFBR1*6A by epithelial and stromal cells during head and neck and colon cancer development. Hum Mol Genet (2007) 0.92
No major tumorigenic role for beta-catenin in serrated as opposed to conventional colorectal adenomas. Br J Cancer (2003) 0.85
Nuclear beta-catenin expression is closely related to ulcerative growth of colorectal carcinoma. Br J Cancer (2002) 0.83
Chemoprevention by white currant is mediated by the reduction of nuclear beta-catenin and NF-kappaB levels in Min mice adenomas. Eur J Nutr (2008) 0.82
Disordered beta-catenin expression and E-cadherin/CDH1 promoter methylation in gastric carcinoma. World J Gastroenterol (2006) 0.82
Effects of gastrin 17 on beta-catenin/Tcf-4 pathway in Colo320WT colon cancer cells. World J Gastroenterol (2006) 0.81
Detection of β-catenin, gastrokine-2 and embryonic stem cell expressed ras in gastric cancers. Int J Clin Exp Pathol (2010) 0.79
The elements of human cyclin D1 promoter and regulation involved. Clin Epigenetics (2011) 0.79
Modulation of human telomerase reverse transcriptase in hepatocellular carcinoma. World J Gastroenterol (2004) 0.79
Long non-coding RNA UCA1 contributes to the progression of oral squamous cell carcinoma by regulating the WNT/β-catenin signaling pathway. Cancer Sci (2016) 0.77
Frizzled10 mediates WNT1 and WNT3A signaling in the dorsal spinal cord of the developing chick embryo. Dev Dyn (2014) 0.77
Therapeutic aspects of c-MYC signaling in inflammatory and cancerous colonic diseases. World J Gastroenterol (2016) 0.77
Biotin-rich intranuclear inclusions in morule-lacking adenocarcinoma of the gallbladder: a new category of "neoplastic/non-morular" lesions. Virchows Arch (2005) 0.76
Gene expression profiling in familial adenomatous polyposis adenomas and desmoid disease. Hered Cancer Clin Pract (2007) 0.76
Role of neutral ceramidase in colon cancer. FASEB J (2016) 0.76
[Morphogenetic aspects of colorectal cancer]. Pathologe (2003) 0.75
Genetic alterations during colorectal-tumor development. N Engl J Med (1988) 26.82
Lessons from hereditary colorectal cancer. Cell (1996) 25.73
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science (1997) 24.61
Identification of c-MYC as a target of the APC pathway. Science (1998) 24.25
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science (1997) 22.80
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature (1999) 20.34
The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors. Nature (1998) 5.16
Drosophila Tcf and Groucho interact to repress Wingless signalling activity. Nature (1998) 4.50
Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas. Proc Natl Acad Sci U S A (1999) 4.35
Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway. Am J Pathol (1999) 4.04
The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors. Oncogene (1999) 3.95
beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am J Pathol (1999) 3.47
Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways. Proc Natl Acad Sci U S A (1998) 3.35
Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature (1998) 2.98
Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly. Mol Biol Cell (1998) 2.71
The Wnt/Wg signal transducer beta-catenin controls fibronectin expression. Mol Cell Biol (1999) 2.68
Nuclear overexpression of the oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front. Pathol Res Pract (1998) 2.63
Beta-catenin mutations are more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas. Cancer Res (1999) 2.09
C-myc overexpression and p53 loss cooperate to promote genomic instability. Oncogene (1999) 1.34
Reciprocity between membranous and nuclear expression of beta-catenin in colorectal tumours. Virchows Arch (1997) 1.28
Cadherin-catenin expression in primary colorectal cancer: a survival analysis. Br J Cancer (1999) 1.26
Microvascular structure of benign and malignant tumors of the colon in humans. Dig Dis Sci (1995) 0.98
The Vienna classification of gastrointestinal epithelial neoplasia. Gut (2000) 9.39
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc Natl Acad Sci U S A (2001) 7.99
Nucleotide sequence of an RNA polymerase binding site from the DNA of bacteriophage fd. Proc Natl Acad Sci U S A (1975) 7.14
Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis. Gastroenterology (1992) 4.19
Exons encode functional and structural units of chicken lysozyme. Proc Natl Acad Sci U S A (1980) 4.01
Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11. Hum Mol Genet (1996) 3.78
beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am J Pathol (1999) 3.47
A gene (RPGR) with homology to the RCC1 guanine nucleotide exchange factor is mutated in X-linked retinitis pigmentosa (RP3). Nat Genet (1996) 3.31
Central nervous system lesions and cervical disc herniations in amateur divers. Lancet (1995) 2.84
KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program. Virchows Arch (2008) 2.78
Imported lassa fever in Germany: molecular characterization of a new lassa virus strain. Emerg Infect Dis (2000) 2.69
Nuclear overexpression of the oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front. Pathol Res Pract (1998) 2.63
Multiple mRNAs are generated from the chicken lysozyme gene. Cell (1981) 2.46
CD133 expression is an independent prognostic marker for low survival in colorectal cancer. Br J Cancer (2008) 2.23
Genetic and functional characterization of the alpAB gene locus essential for the adhesion of Helicobacter pylori to human gastric tissue. Mol Microbiol (1999) 2.06
Role of virus strain in conventional and enhanced measles plaque neutralization test. J Virol Methods (1981) 1.96
Expression of the invasion factor laminin gamma2 in colorectal carcinomas is regulated by beta-catenin. Cancer Res (2001) 1.83
The binding of pyrophosphate and two diphosphonates by hydroxyapatite crystals. Calcif Tissue Res (1973) 1.77
Association between infection with Helicobacter pylori and Chlamydia pneumoniae and risk of ischemic stroke subtypes: Results from a population-based case-control study. Stroke (2001) 1.76
The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation. Am J Pathol (2001) 1.73
Antrum- and corpus mucosa-infiltrating CD4(+) lymphocytes in Helicobacter pylori gastritis display a Th1 phenotype. Infect Immun (1998) 1.67
Lack of association of nonautoimmune hyperfunctioning thyroid disorders and a germline polymorphism of codon 727 of the human thyrotropin receptor in a European Caucasian population. J Clin Endocrinol Metab (2000) 1.62
Rapid and specific detection of Helicobacter pylori macrolide resistance in gastric tissue by fluorescent in situ hybridisation. Gut (2000) 1.62
Characterization of a protein with an acetylcholine receptor epitope from myasthenia gravis-associated thymomas. Lab Invest (1990) 1.60
Growth and symptoms in Silver-Russell syndrome: review on the basis of 386 patients. Eur J Pediatr (1995) 1.59
Development of a standard set of microsatellite reference alleles for identification of grape cultivars. Theor Appl Genet (2004) 1.52
Risk of congenital abnormality after inadvertent rubella vaccination of pregnant women. N Engl J Med (1976) 1.50
Systemic scleroderma. Multicenter trial of 1 year of treatment with recombinant interferon gamma. Arch Dermatol (1997) 1.49
The detection rate of [11C]choline-PET/CT depends on the serum PSA-value in patients with biochemical recurrence of prostate cancer. Eur J Nucl Med Mol Imaging (2007) 1.46
Overexpression of Dicer predicts poor survival in colorectal cancer. Eur J Cancer (2011) 1.46
Lack of evidence for an involvement of Epstein-Barr virus infection of synovial membranes in the pathogenesis of rheumatoid arthritis. Arthritis Rheum (2000) 1.40
Innate immunity in cystic fibrosis lung disease. J Cyst Fibros (2012) 1.38
[Comparison of a high-end ultrasound system with a spiral CT scanner in screening for liver metastases]. Ultraschall Med (1998) 1.38
Balanitis xerotica obliterans in monozygotic twins. Br J Urol (1997) 1.38
An updated systematic review of Health State Utility Values for osteoporosis related conditions. Osteoporos Int (2009) 1.31
Heterogeneity among Whipple's-disease-associated bacteria. Lancet (1994) 1.28
Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. Arthritis Rheum (2000) 1.27
Mechanisms of sulfadoxine resistance in Plasmodium falciparum. Mol Biochem Parasitol (1986) 1.27
The gastric H+,K+-ATPase is a major autoantigen in chronic Helicobacter pylori gastritis with body mucosa atrophy. Gastroenterology (1998) 1.26
Negative regulation of CD4 expression in T cells by the transcriptional repressor ZEB. Int Immunol (1999) 1.24
Lewis X structures in the O antigen side-chain promote adhesion of Helicobacter pylori to the gastric epithelium. Mol Microbiol (2000) 1.23
Stage-dependent inhibition of chloroquine on Plasmodium falciparum in vitro. J Parasitol (1986) 1.21
Thymus in myasthenia gravis. Isolation of T-lymphocyte lines specific for the nicotinic acetylcholine receptor from thymuses of myasthenic patients. J Clin Invest (1988) 1.21
After shrinkage apoptotic cells expose internal membrane-derived epitopes on their plasma membranes. Cell Death Differ (2006) 1.21
Predictive value of nuclear beta-catenin expression for the occurrence of distant metastases in rectal cancer. Dis Colon Rectum (1998) 1.20
Late pulmonary metastasis in uterine PEComa. J Clin Pathol (2003) 1.20
Rat monoclonal antibodies differentiating between the Epstein-Barr virus nuclear antigens 2A (EBNA2A) and 2B (EBNA2B). Virology (1995) 1.18
Epidemiology of Whipple's disease in Germany. Analysis of 110 patients diagnosed in 1965-95. Scand J Gastroenterol (1997) 1.16
Chondroblastoma is an osteoid-forming, but not cartilage-forming neoplasm. J Pathol (1999) 1.14
Expression of the extracellular matrix signaling molecule Cyr61 is downregulated in prostate cancer. Prostate (1998) 1.14
CTLA4Ig inhibits airway eosinophilia and hyperresponsiveness by regulating the development of Th1/Th2 subsets in a murine model of asthma. Am J Respir Cell Mol Biol (1998) 1.14
Antigastric autoantibodies in Helicobacter pylori infection: implications of histological and clinical parameters of gastritis. Gut (1997) 1.13
The monoclonal antibody AS02 recognizes a protein on human fibroblasts being highly homologous to Thy-1. Arch Dermatol Res (1998) 1.12
Neutrophil priming by cytokines and vitamin D binding protein (Gc-globulin): impact on C5a-mediated chemotaxis, degranulation and respiratory burst. Mol Immunol (2000) 1.12
TRFK-5 reverses established airway eosinophilia but not established hyperresponsiveness in a murine model of chronic asthma. Am J Respir Crit Care Med (1999) 1.11
Antigastric autoantibodies in Helicobacter pylori gastritis: prevalence, in-situ binding sites and clues for clinical relevance. Virchows Arch (1996) 1.10
Helicobacter pylori induces apoptosis in gastric mucosa through an upregulation of Bax expression in humans. Scand J Gastroenterol (1999) 1.10
Silica-induced scleroderma. J Am Acad Dermatol (1990) 1.09
Characterization of lymphocytic infiltrates in Helicobacter pylori-associated gastritis. Scand J Gastroenterol (1996) 1.09
Fate of intravenously injected pyrophosphate-32P in dogs. Am J Physiol (1970) 1.07
Novel fibroblast-specific monoclonal antibodies: properties and specificities. J Invest Dermatol (1996) 1.07
Immunohistological evidences of cortical and medullary differentiation in thymoma. Virchows Arch A Pathol Anat Histopathol (1985) 1.07
EGFR pathway biomarkers in erlotinib-treated patients with advanced pancreatic cancer: translational results from the randomised, crossover phase 3 trial AIO-PK0104. Br J Cancer (2012) 1.07
Left-sided primary tumors are associated with favorable prognosis in patients with KRAS codon 12/13 wild-type metastatic colorectal cancer treated with cetuximab plus chemotherapy: an analysis of the AIO KRK-0104 trial. J Cancer Res Clin Oncol (2014) 1.07
[The phenolics of fruits. VIII. Changes in flavonol concentrations during fruit development (authors transl)]. Z Lebensm Unters Forsch (1976) 1.06
ANT1, an aromatic and neutral amino acid transporter in Arabidopsis. Plant Physiol (2001) 1.06
Plasmodium vinckei: suppression of mouse infections with desferrioxamine B. Exp Parasitol (1985) 1.05
Efficacy of surgical measures in preventing port-site recurrences in a porcine model. Surg Endosc (2001) 1.04
Bugs on trial: the case of Helicobacter pylori and autoimmunity. Immunol Today (1998) 1.04
ANCA-associated vasculitis is linked to carriage of the Z allele of α₁ antitrypsin and its polymers. Ann Rheum Dis (2011) 1.04
Inorganic pyrophosphate pool size and turnover rate in arthritic joints. J Clin Invest (1975) 1.03
Correlation of serum level of high mobility group box 1 with the burden of granulomatous inflammation in granulomatosis with polyangiitis (Wegener's). Ann Rheum Dis (2011) 1.03
Monoclonal Epstein-Barr virus genomes but lack of EBV-related protein expression in different types of gastric carcinoma. Histopathology (1994) 1.03
Nodal CT density and total tumor volume as prognostic factors after radiation therapy of stage III/IV head and neck cancer. Radiother Oncol (1998) 1.02
Pseudoappendicitis caused by Plesiomonas shigelloides. J Clin Microbiol (1988) 1.01
Cell differentiation and matrix gene expression in mesenchymal chondrosarcomas. Am J Pathol (2000) 1.00
Developmental changes revealed by immunohistochemical markers in human cerebral cortex. Cereb Cortex (1997) 1.00
CD28 interactions with either CD80 or CD86 are sufficient to induce allergic airway inflammation in mice. Am J Respir Cell Mol Biol (1999) 1.00
Bone and renal components in hypercalcemia of malignancy and responses to a single infusion of clodronate. Bone (1988) 1.00
Crohn disease of the small bowel proximal to the terminal ileum: detection by MR-enteroclysis. Scand J Gastroenterol (2004) 1.00