Published in J Clin Invest on March 01, 1988
Microarrays reveal distinct gene signatures in the thymus of seropositive and seronegative myasthenia gravis patients and the role of CC chemokine ligand 21 in thymic hyperplasia. J Immunol (2006) 1.47
A juxta-membrane epitope on the human acetylcholine receptor recognized by T cells in myasthenia gravis. J Clin Invest (1988) 1.19
Ocular myasthenia gravis: response to long-term immunosuppressive treatment. J Neurol Neurosurg Psychiatry (1997) 1.11
Autoimmune T lymphocytes in myasthenia gravis. Determination of target epitopes using T lines and recombinant products of the mouse nicotinic acetylcholine receptor gene. J Clin Invest (1989) 1.04
Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis. J Clin Invest (2003) 1.04
Immunodominant regions for T helper-cell sensitization on the human nicotinic receptor alpha subunit in myasthenia gravis. Proc Natl Acad Sci U S A (1990) 1.00
Muscle autoantibodies in myasthenia gravis: beyond diagnosis? Expert Rev Clin Immunol (2012) 0.98
Oral administration of a dual analog of two myasthenogenic T cell epitopes down-regulates experimental autoimmune myasthenia gravis in mice. Proc Natl Acad Sci U S A (2000) 0.92
Transplantation of thymic autoimmune microenvironment to severe combined immunodeficiency mice. A new model of myasthenia gravis. J Clin Invest (1992) 0.89
T helper cell recognition of muscle acetylcholine receptor in myasthenia gravis. Epitopes on the gamma and delta subunits. J Clin Invest (1993) 0.89
Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis. Oncotarget (2016) 0.81
Circulating regulatory anti-T cell receptor antibodies in patients with myasthenia gravis. J Clin Invest (2003) 0.80
Phenotypic and functional characterization of T cells from patients with myasthenia gravis. J Clin Invest (1990) 0.80
Acetylcholine receptor alpha-subunit isoforms are differentially expressed in thymuses from myasthenic patients. Am J Pathol (1997) 0.78
Thymectomy and azathioprine have no effect on the phenotype of CD4 T lymphocyte subsets in myasthenia gravis. J Neurol Neurosurg Psychiatry (1993) 0.78
Overexpression of select T cell receptor V beta gene families within CD4+ and CD8+ T cell subsets of myasthenia gravis patients: a role for superantigen(s)? Mol Med (1996) 0.77
Thymoma-associated myasthenia gravis. Transplantation of thymoma and extrathymomal thymic tissue into SCID mice. Am J Pathol (1996) 0.76
Vaccines against myasthenia gravis. Expert Opin Biol Ther (2005) 0.76
Animal models of myasthenia gravis: utility and limitations. Int J Gen Med (2016) 0.75
Schwann cells and myasthenia gravis. Preferential uptake of soluble and membrane-bound AChR by normal and immortalized Schwann cells, and immunogenic presentation to AChR-specific T line lymphocytes. Am J Pathol (1990) 0.75
Autoimmune disease and the nervous system. West J Med (1992) 0.75
Antibodies to acetylcholine receptors in myasthenia gravis. In vitro synthesis by peripheral blood lymphocytes before and after thymectomy. Clin Exp Immunol (1992) 0.75
Use of Toll-Like Receptor Agonists to Induce Ectopic Lymphoid Structures in Myasthenia Gravis Mouse Models. Front Immunol (2017) 0.75
Antigen presentation: comments on its regulation and mechanism. J Immunol (1984) 3.68
Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication. J Exp Med (1983) 3.20
Identification of Hodgkin and Sternberg-reed cells as a unique cell type derived from a newly-detected small-cell population. Int J Cancer (1982) 2.51
A simple assay for the study of solubilized acetylcholine receptors. Anal Biochem (1973) 2.44
Clinical, pathological, HLA antigen and immunological evidence for disease heterogeneity in myasthenia gravis. Brain (1980) 2.36
Myasthenia gravis. Study of humoral immune mechanisms by passive transfer to mice. N Engl J Med (1977) 2.23
The pathology of the thymus gland in myasthenia gravis. Ann N Y Acad Sci (1966) 1.80
Thymic cytotoxic T lymphocytes are primed in vivo to minor histocompatibility antigens. J Exp Med (1984) 1.63
Autoimmune human T lymphocytes specific for acetylcholine receptor. Nature (1984) 1.63
Cellular immune response to acetylcholine receptor-rich fraction, in patients with myasthenia gravis. Clin Exp Immunol (1975) 1.59
The thymus in myasthenia gravis. Evidence for altered cell populations. N Engl J Med (1974) 1.50
Functional activities of autoantibodies to acetylcholine receptors and the clinical severity of myasthenia gravis. N Engl J Med (1982) 1.45
Effector T lymphocyte line cells migrate to the thymus and persist there. Nature (1982) 1.44
Thymic muscle cells bear acetylcholine receptors: possible relation to myasthenia gravis. Science (1977) 1.36
Monoclonal antibody Ki-M4 specifically recognizes human dendritic reticulum cells (follicular dendritic cells) and their possible precursor in blood. Blood (1983) 1.32
Intrathymic pathogenesis and dual genetic control of myasthenia gravis. Lancet (1977) 1.27
A histologic reappraisal of the thymus in myasthenia gravis. A correlative study of thymic pathology and response to thymectomy. Arch Pathol (1971) 1.27
Monocyte/macrophage-specific monoclonal antibody Ki-M1 recognizes interdigitating reticulum cells. Am J Pathol (1984) 1.24
Spontaneous remission and acquired resistance to autoimmune encephalomyelitis (EAE) are associated with suppression of T cell reactivity: suppressed EAE effector T cells recovered as T cell lines. J Immunol (1982) 1.24
Intrathymic presentation of circulating non-major histocompatibility complex antigens. Nature (1984) 1.22
Thymic myogenesis, T-lymphocytes and the pathogenesis of myasthenia gravis. Ann N Y Acad Sci (1981) 1.14
In-vitro synthesis of anti-acetylcholine-receptor antibody by thymic lymphocytes in myasthenia gravis. Lancet (1978) 1.12
Microenvironments in the normal thymus and the thymus in myasthenia gravis. Am J Pathol (1985) 1.12
Combined immunohistochemical staining for surface IgD and T-lymphocyte subsets with monoclonal antibodies in human tonsils. Histochem J (1983) 1.07
Interdigitating reticulum cells in the human thymus. Cell Tissue Res (1974) 1.05
Myasthenia gravis: stimulation of antireceptor autoantibodies by autoreactive T cell lines. Neurology (1986) 1.04
Thymus cells in myasthenia gravis selectively enhance production of anti-acetylcholine-receptor antibody by autologous blood lymphocytes. N Engl J Med (1981) 1.02
Striated muscle fibres differentiate in monolayer cultures of adult thymus reticulum. Nature (1975) 1.02
A prospective study of thymectomy and serum acetylcholine receptor antibodies in myasthenia gravis. Ann Surg (1982) 0.99
Cellular immune response against acetylcholine receptor in myasthenia gravis: I. Relevance to clinical course and pathogenesis. Neurology (1979) 0.97
Immunohistological patterns of non-neoplastic changes in the thymus in Myasthenia gravis. Virchows Arch B Cell Pathol Incl Mol Pathol (1986) 0.93
Intrathymic pathogenesis of myasthenia gravis: transient expression of acetylcholine receptors on thymus-derived myogenic cells. Eur J Immunol (1978) 0.91
Cellular immunity to acetylcholine receptor in myasthenia gravis: relationship to histocompatibility type and antigenic site. Neurology (1979) 0.89
Myasthenia gravis with thymoma: analysis of and postoperative prognosis for 65 patients with thymomatous myasthenia gravis. Ann Thorac Surg (1984) 0.88
Monoclonal antibody to acetylcholine receptor: cell line established from thymus of patient with Myasthenia gravis. Science (1982) 0.88
Genetic restriction of autoreactive acetylcholine receptor-specific T lymphocytes in myasthenia gravis. J Immunol (1985) 0.88
Effects of preoperative duration of symptoms on patients with myasthenia gravis. Ann Thorac Surg (1984) 0.86
Autoreactivity between lymphocytes and thymus cells in myasthenia gravis. Arch Neurol (1978) 0.86
Thymic abnormalities: antigen or antibody? Response to thymectomy in myasthenia gravis. Ann N Y Acad Sci (1981) 0.85
Molecular forms and hydrodynamic properties of acetylcholine receptor from electric tissue. Eur J Biochem (1981) 0.84
Acetylcholine receptor antibody-producing cells in thymus and lymph nodes in myasthenia gravis. Clin Immunol Immunopathol (1985) 0.83
Thymic B-cell activation in myasthenia gravis. Neurology (1984) 0.80
The predominant lymphocyte in most thymomas and in nonneoplastic thymus from patients with myasthenia gravis is the cortical thymocyte. Clin Immunol Immunopathol (1985) 0.80
The thymus in myasthenia gravis. Curr Top Pathol (1986) 0.79
Thymus in myasthenia gravis: a light and electron microscopic study of a case with thymic follicular hyperplasia. Pathol Res Pract (1984) 0.77
The Vienna classification of gastrointestinal epithelial neoplasia. Gut (2000) 9.39
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc Natl Acad Sci U S A (2001) 7.99
Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis. Gastroenterology (1992) 4.19
The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. Eur J Immunol (1981) 3.96
Astrocytes present myelin basic protein to encephalitogenic T-cell lines. Nature (1984) 3.71
Recombinant outer surface protein a from Borrelia burgdorferi induces antibodies protective against spirochetal infection in mice. J Infect Dis (1991) 3.58
beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am J Pathol (1999) 3.47
Quality assurance in immunohistochemistry: results of an interlaboratory trial involving 172 pathologists. Am J Surg Pathol (2002) 3.05
Induction of MHC class I genes in neurons. Science (1995) 2.84
Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? J Exp Med (1999) 2.84
KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program. Virchows Arch (2008) 2.78
Migratory activity and functional changes of green fluorescent effector cells before and during experimental autoimmune encephalomyelitis. Immunity (2001) 2.77
Primary gastric B-cell lymphoma: results of a prospective multicenter study. The German-Austrian Gastrointestinal Lymphoma Study Group. Gastroenterology (2000) 2.65
Nuclear overexpression of the oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front. Pathol Res Pract (1998) 2.63
Vaccination against autoimmune encephalomyelitis with T-lymphocyte line cells reactive against myelin basic protein. Nature (1981) 2.44
The involution of the ageing human thymic epithelium is independent of puberty. A morphometric study. Scand J Immunol (1985) 2.40
Peripheral T-cell lymphoma (excluding anaplastic large-cell lymphoma): results from the Non-Hodgkin's Lymphoma Classification Project. Ann Oncol (2002) 2.28
Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice. J Immunol (2001) 2.27
MALT-type lymphoma of the stomach is associated with Helicobacter pylori strains expressing the CagA protein. Gastroenterology (1997) 2.25
CD133 expression is an independent prognostic marker for low survival in colorectal cancer. Br J Cancer (2008) 2.23
Thymic nurse cells. Lymphoepithelial cell complexes in murine thymuses: morphological and serological characterization. J Exp Med (1980) 2.23
Admission criteria for immunogerontological studies in man: the SENIEUR protocol. Mech Ageing Dev (1984) 2.22
Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis. Neurology (2011) 2.07
Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma. Leukemia (2007) 2.03
Constitutive NF-kappa B activity in neurons. Mol Cell Biol (1994) 1.96
Myelin autoreactivity in multiple sclerosis: recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple-sclerosis patients and healthy donors. Proc Natl Acad Sci U S A (1990) 1.93
Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation. J Immunol (1985) 1.88
B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice. J Exp Med (1998) 1.85
Expression of the invasion factor laminin gamma2 in colorectal carcinomas is regulated by beta-catenin. Cancer Res (2001) 1.83
Thymic nurse cells--Ia-bearing epithelium involved in T-lymphocyte differentiation? Nature (1980) 1.83
Is sclerosing angiomatoid nodular transformation (SANT) of the splenic red pulp identical to inflammatory pseudotumour? Report of 16 cases. Histopathology (2008) 1.82
Capillary deposition of C4d complement fragment and early renal graft loss. Kidney Int (1993) 1.80
The distribution of Ia antigen in the lesions of rat acute experimental allergic encephalomyelitis. Acta Neuropathol (1986) 1.77
T cells specific for the myelin oligodendrocyte glycoprotein mediate an unusual autoimmune inflammatory response in the central nervous system. Eur J Immunol (1993) 1.74
The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation. Am J Pathol (2001) 1.73
Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T-T cell interactions. Nature (1988) 1.71
Differential expression of CD44 splice variants in intestinal- and diffuse-type human gastric carcinomas and normal gastric mucosa. Cancer Res (1993) 1.68
Antrum- and corpus mucosa-infiltrating CD4(+) lymphocytes in Helicobacter pylori gastritis display a Th1 phenotype. Infect Immun (1998) 1.67
Expression of nuclear beta-catenin and c-myc is correlated with tumor size but not with proliferative activity of colorectal adenomas. Am J Pathol (2000) 1.66
Rapid and specific detection of Helicobacter pylori macrolide resistance in gastric tissue by fluorescent in situ hybridisation. Gut (2000) 1.62
Myelin basic protein-specific T lymphocyte lines from MS patients and healthy individuals. Neurology (1990) 1.61
Characterization of a protein with an acetylcholine receptor epitope from myasthenia gravis-associated thymomas. Lab Invest (1990) 1.60
Growth and symptoms in Silver-Russell syndrome: review on the basis of 386 patients. Eur J Pediatr (1995) 1.59
The t(11;18)(q21;q21) chromosome translocation is a frequent and specific aberration in low-grade but not high-grade malignant non-Hodgkin's lymphomas of the mucosa-associated lymphoid tissue (MALT-) type. Cancer Res (1997) 1.59
Idiotype identity in a MALT-type lymphoma and B cells in Helicobacter pylori associated chronic gastritis. Lab Invest (1994) 1.58
Recurrent genetic aberrations in thymoma and thymic carcinoma. Am J Pathol (2000) 1.53
Multiple sclerosis: comparison of copolymer-1- reactive T cell lines from treated and untreated subjects reveals cytokine shift from T helper 1 to T helper 2 cells. Proc Natl Acad Sci U S A (2000) 1.53
Thymoma and thymic carcinoma. Relation of thymoma epithelial cells to the cortical and medullary differentiation of thymus. Virchows Arch A Pathol Anat Histopathol (1985) 1.51
[Pathology--availability and utilization]. Pathologe (1993) 1.51
Genetic control of multiple sclerosis: increased production of lymphotoxin and tumor necrosis factor-alpha by HLA-DR2+ T cells. Ann Neurol (1995) 1.50
Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain. Am J Pathol (1993) 1.50
Chronic non-bacterial osteomyelitis in children. Ann Rheum Dis (2005) 1.49
Gain of chromosome arm 9p is characteristic of primary mediastinal B-cell lymphoma (MBL): comprehensive molecular cytogenetic analysis and presentation of a novel MBL cell line. Genes Chromosomes Cancer (2001) 1.49
Chronic recurrent multifocal osteomyelitis in children: diagnostic value of histopathology and microbial testing. Hum Pathol (1999) 1.49
Experimental autoimmune encephalomyelitis: the antigen specificity of T lymphocytes determines the topography of lesions in the central and peripheral nervous system. Lab Invest (1997) 1.47
Neurotrophins inhibit major histocompatibility class II inducibility of microglia: involvement of the p75 neurotrophin receptor. Proc Natl Acad Sci U S A (1998) 1.47
Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: epitope spreading versus clonal persistence. Brain (2000) 1.47
Overexpression of Dicer predicts poor survival in colorectal cancer. Eur J Cancer (2011) 1.46
Detection of DNA fragmentation in apoptosis: application of in situ nick translation to cell culture systems and tissue sections. J Histochem Cytochem (1993) 1.44
[Detection of DNA of human papillomaviruses (HPV) in an "aggressively" growing cholesteatoma. Is cholesteatoma a virus-induced tumor?]. HNO (1995) 1.43
Gene transfer into CD4+ T lymphocytes: green fluorescent protein-engineered, encephalitogenic T cells illuminate brain autoimmune responses. Nat Med (1999) 1.42
Vascular deposition of complement-split products in kidney allografts with cell-mediated rejection. Clin Exp Immunol (1991) 1.42
Diversity of the anti-T-cell receptor immune response and its implications for T-cell vaccination therapy of multiple sclerosis. Brain (1998) 1.41
Lack of evidence for an involvement of Epstein-Barr virus infection of synovial membranes in the pathogenesis of rheumatoid arthritis. Arthritis Rheum (2000) 1.40
Routine molecular genotyping of HLA-B27 in spondyloarthropathies overcomes the obstacles of serological typing and reveals an increased B *2702 frequency in ankylosing spondylitis. J Rheumatol (1997) 1.39
Human myoblasts as antigen-presenting cells. J Immunol (1992) 1.39
Borna disease, a progressive meningoencephalomyelitis as a model for CD4+ T cell-mediated immunopathology in the brain. J Exp Med (1989) 1.39
IDDM2/insulin VNTR modifies risk conferred by IDDM1/HLA for development of Type 1 diabetes and associated autoimmunity. Diabetologia (2003) 1.37
Polymorphous high-grade B cell lymphoma is the predominant type of spontaneous primary cerebral malignant lymphomas. Histological and immunomorphological evaluation of computed tomography-guided stereotactic brain biopsies. Am J Surg Pathol (1994) 1.37
Thymomas alter the T-cell subset composition in the blood: a potential mechanism for thymoma-associated autoimmune disease. Blood (2000) 1.35
Ia-restricted encephalitogenic T lymphocytes mediating EAE lyse autoantigen-presenting astrocytes. Nature (1986) 1.33
Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100 beta molecule, a calcium binding protein of astroglia. J Exp Med (1994) 1.33
An approach to the localization of the susceptibility genes for generalized myasthenia gravis by mapping recombinant ancestral haplotypes. Immunogenetics (1992) 1.32
Characterization of the B-cell and T-cell regions of human lymphatic tissue through enzyme histochemical demonstration of ATPase and 5'-nucleotidase activities. Virchows Arch B Cell Pathol (1974) 1.31
Fractionation of antigen reactive cells on a cellular immunoadsorbent: factors determining recognition of antigens by T-lymphocytes. Proc Natl Acad Sci U S A (1972) 1.31
Mechanisms of action of glatiramer acetate in multiple sclerosis. Neurology (2001) 1.30
Interferon gamma gene expression in sensory neurons: evidence for autocrine gene regulation. J Exp Med (1997) 1.29
A20 deletion is associated with copy number gain at the TNFA/B/C locus and occurs preferentially in translocation-negative MALT lymphoma of the ocular adnexa and salivary glands. J Pathol (2009) 1.29
Immunological update on multiple sclerosis. Curr Opin Neurol (2001) 1.28
Heterogeneity among Whipple's-disease-associated bacteria. Lancet (1994) 1.28
Intrathymic pathogenesis and dual genetic control of myasthenia gravis. Lancet (1977) 1.27
Pathogenesis of myasthenia gravis. Acetylcholine receptor-related antigenic determinants in tumor-free thymuses and thymic epithelial tumors. Am J Pathol (1988) 1.27
Blastoid variants of mantle cell lymphoma: frequent bcl-1 rearrangements at the major translocation cluster region and tetraploid chromosome clones. Blood (1997) 1.27
The gastric H+,K+-ATPase is a major autoantigen in chronic Helicobacter pylori gastritis with body mucosa atrophy. Gastroenterology (1998) 1.26
Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes. Am J Pathol (2001) 1.26
CXC chemokines Gro(alpha)/IL-8 and IP-10/MIG in Helicobacter pylori gastritis. Clin Exp Immunol (2000) 1.25
Differential expression of perforin in muscle-infiltrating T cells in polymyositis and dermatomyositis. J Clin Invest (1996) 1.24
Negative regulation of CD4 expression in T cells by the transcriptional repressor ZEB. Int Immunol (1999) 1.24
Neuronal control of the immune response in the central nervous system: linking brain immunity to neurodegeneration. J Neuropathol Exp Neurol (1998) 1.22
A permanent rat T cell line that mediates experimental allergic neuritis in the Lewis rat in vivo. J Immunol (1984) 1.21
Regulation of autosensitization. The immune activation and specific inhibition of self-recognizing thymus-derived lymphocytes. J Exp Med (1973) 1.20
Predictive value of nuclear beta-catenin expression for the occurrence of distant metastases in rectal cancer. Dis Colon Rectum (1998) 1.20