Published in Mamm Genome on March 01, 2000
Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice. Proc Natl Acad Sci U S A (2004) 2.87
Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation. Epigenetics (2007) 2.30
Protein interactions targeting the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus to cell chromosomes. J Virol (2002) 2.28
Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome. Genome Res (2002) 1.80
The major form of MeCP2 has a novel N-terminus generated by alternative splicing. Nucleic Acids Res (2004) 1.79
Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription. Nucleic Acids Res (2001) 1.64
Rett syndrome and MeCP2: linking epigenetics and neuronal function. Am J Hum Genet (2002) 1.42
Complexities of Rett syndrome and MeCP2. J Neurosci (2011) 1.35
Experimental models of Rett syndrome based on Mecp2 dysfunction. Exp Biol Med (Maywood) (2011) 1.27
Diagnostic testing for Rett syndrome by DHPLC and direct sequencing analysis of the MECP2 gene: identification of several novel mutations and polymorphisms. Am J Hum Genet (2000) 1.23
X chromosome choice occurs independently of asynchronous replication timing. J Cell Biol (2005) 1.14
MeCP2 mutation results in compartment-specific reductions in dendritic branching and spine density in layer 5 motor cortical neurons of YFP-H mice. PLoS One (2012) 0.97
Capturing microRNA targets using an RNA-induced silencing complex (RISC)-trap approach. Proc Natl Acad Sci U S A (2012) 0.96
MECP2 genomic structure and function: insights from ENCODE. Nucleic Acids Res (2008) 0.93
Child and adolescent psychiatric genetics. Eur Child Adolesc Psychiatry (2010) 0.86
In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system. Eur J Neurosci (2011) 0.86
MeCP2 expression and promoter methylation of cyclin D1 gene are associated with cyclin D1 expression in developing rat epididymal duct. Acta Histochem Cytochem (2008) 0.83
MECP2, a gene associated with Rett syndrome in humans, shows conserved coding regions, independent Alu insertions, and a novel transcript across primate evolution. BMC Genet (2015) 0.78
Regulatory functions and pathological relevance of the MECP2 3'UTR in the central nervous system. Cell Regen (Lond) (2015) 0.76
Mitochondrial Dysfunction in the Pathogenesis of Rett Syndrome: Implications for Mitochondria-Targeted Therapies. Front Cell Neurosci (2017) 0.75
MeCP2-Related Diseases and Animal Models. Diseases (2014) 0.75
First case report of Rett syndrome in the Azeri Turkish population and brief review of the literature. Epilepsy Behav Case Rep (2015) 0.75
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
A physical map of the human genome. Nature (2001) 12.39
The DNA sequence of human chromosome 21. Nature (2000) 10.66
The genome of the social amoeba Dictyostelium discoideum. Nature (2005) 9.18
Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature (1998) 7.43
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron (2000) 6.92
Molecular basis of symbiosis between Rhizobium and legumes. Nature (1997) 6.66
Bisulfite genomic sequencing: systematic investigation of critical experimental parameters. Nucleic Acids Res (2001) 5.89
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature (1996) 5.69
Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters. Nature (1993) 5.05
Pseudoautosomal deletions encompassing a novel homeobox gene cause growth failure in idiopathic short stature and Turner syndrome. Nat Genet (1997) 4.95
Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell (1998) 4.72
DNA sequences required for regulated expression of beta-globin genes in murine erythroleukemia cells. Cell (1984) 4.42
DNA sequence and comparative analysis of chimpanzee chromosome 22. Nature (2004) 4.12
Renal and neuronal abnormalities in mice lacking GDNF. Nature (1996) 4.06
Positional cloning of the gene for X-linked retinitis pigmentosa 2. Nat Genet (1998) 4.01
A nuclear DNA attachment element mediates elevated and position-independent gene activity. Nature (1989) 3.80
A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast. Nat Genet (1996) 3.67
GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science (1994) 3.63
Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium. Nature (2000) 3.61
FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell (1998) 3.33
Sequence requirements for the transcription of the rabbit beta-globin gene in vivo: the -80 region. Nucleic Acids Res (1982) 3.11
Topical ketorolac tromethamine 0.5% ophthalmic solution in ocular inflammation after cataract surgery. Ophthalmology (2001) 3.01
Post-processing long pairwise alignments. Bioinformatics (1999) 3.00
Characterization of a multicomponent receptor for GDNF. Nature (1996) 2.92
Drinks like a fish: zebra fish (Danio rerio) as a behavior genetic model to study alcohol effects. Pharmacol Biochem Behav (2000) 2.83
Genetic hitch-hiking in a subdivided population. Genet Res (1998) 2.73
The matrix attachment regions of the chicken lysozyme gene co-map with the boundaries of the chromatin domain. EMBO J (1988) 2.66
THE FILTRATION RATE, EFFECTIVE RENAL BLOOD FLOW, TUBULAR EXCRETORY MASS AND PHENOL RED CLEARANCE IN SPECIFIC TOXEMIA OF PREGANANCY. J Clin Invest (1942) 2.65
X-linked spastic paraplegia (SPG1), MASA syndrome and X-linked hydrocephalus result from mutations in the L1 gene. Nat Genet (1994) 2.53
An L-type calcium-channel gene mutated in incomplete X-linked congenital stationary night blindness. Nat Genet (1998) 2.48
N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom. Am J Hum Genet (2000) 2.47
Expression in rat fibroblasts of a human transforming growth factor-alpha cDNA results in transformation. Cell (1986) 2.41
Noninvasive tests in the initial evaluation of heart murmurs in children. N Engl J Med (1983) 2.39
Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mech Dev (1999) 2.36
GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney. Neuron (1998) 2.34
Continuous subcutaenous administration of deferoxamine in patients with iron overload. N Engl J Med (1977) 2.31
Simian immunodeficiency virus disease course is predicted by the extent of virus replication during primary infection. J Virol (1999) 2.29
Interrupted aortic arch: surgical treatment. Am J Cardiol (1971) 2.24
Mutations in a new gene, encoding a zinc-finger protein, cause tricho-rhino-phalangeal syndrome type I. Nat Genet (2000) 2.23
Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site. Proc Natl Acad Sci U S A (1998) 2.16
A matrix/scaffold attachment region binding protein: identification, purification, and mode of binding. Cell (1991) 2.11
Discovery of new human beta-defensins using a genomics-based approach. Gene (2001) 2.08
Induction of midbrain dopaminergic neurons by Sonic hedgehog. Neuron (1995) 2.08
A genome-wide survey of RAS transformation targets. Nat Genet (2000) 2.06
Neurotrophin-5: a novel neurotrophic factor that activates trk and trkB. Neuron (1991) 2.03
Large-scale methylation analysis of human genomic DNA reveals tissue-specific differences between the methylation profiles of genes and pseudogenes. Hum Mol Genet (2000) 2.02
Multiple pathogenic and benign genomic rearrangements occur at a 35 kb duplication involving the NEMO and LAGE2 genes. Hum Mol Genet (2001) 2.00
The chicken lysozyme 5' matrix attachment region increases transcription from a heterologous promoter in heterologous cells and dampens position effects on the expression of transfected genes. Mol Cell Biol (1990) 1.98
Comparative analysis of the Borrelia garinii genome. Nucleic Acids Res (2004) 1.96
Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32). Nat Genet (1999) 1.96
Sepsis and congenital asplenia. J Pediatr (1977) 1.93
Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. Genomics (2000) 1.88
A regulator of transcriptional elongation controls vertebrate neuronal development. Nature (2000) 1.87
Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex. J Biol Chem (1995) 1.83
Up-regulation of monocytic IL-10 by tumor necrosis factor-alpha and cAMP elevating drugs. Int Immunol (1995) 1.81
Sonic hedgehog signaling by the patched-smoothened receptor complex. Curr Biol (1999) 1.79
Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature (1995) 1.79
Activation of expression of hedgehog target genes in basal cell carcinomas. J Invest Dermatol (2001) 1.77
Lorist6, a cosmid vector with BamHI, NotI, ScaI and HindIII cloning sites and altered neomycin phosphotransferase gene expression. Gene (1987) 1.75
MethTools--a toolbox to visualize and analyze DNA methylation data. Nucleic Acids Res (2000) 1.74
Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli. J Cell Sci (1999) 1.74
Extracardiac abnormalities in infants with congenital heart disease. Pediatrics (1975) 1.73
Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons. Science (1990) 1.71
Ketorolac tromethamine 0.5% ophthalmic solution in the treatment of moderate to severe ocular inflammation after cataract surgery: a randomized, vehicle-controlled clinical trial. Am J Ophthalmol (1999) 1.70
Chicken MAR-binding protein ARBP is homologous to rat methyl-CpG-binding protein MeCP2. Mol Cell Biol (1997) 1.68
Characterization of ATM gene mutations in 66 ataxia telangiectasia families. Hum Mol Genet (1999) 1.66
Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein soulless/Phox2a. Neuron (1999) 1.65
Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1. Neuron (1997) 1.65
Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription. Nucleic Acids Res (2001) 1.64
The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells. Neuron (1993) 1.61
A forty-year review of bacterial endocarditis in infancy and childhood. Circulation (1975) 1.60
Consecutive, prospective case series of a new method for ultrasound-guided supraclavicular approach to the brachiocephalic vein in children. Br J Anaesth (2011) 1.59
Variations in DNA methylation during mouse cell differentiation in vivo and in vitro. Proc Natl Acad Sci U S A (1984) 1.59
Selection for genes encoding secreted proteins and receptors. Proc Natl Acad Sci U S A (1996) 1.58
Vaccine protection of rhesus macaques against simian immunodeficiency virus infection. AIDS Res Hum Retroviruses (1990) 1.56
Comparison of the ocular hypotensive lipid AGN 192024 with timolol: dosing, efficacy, and safety evaluation of a novel compound for glaucoma management. Arch Ophthalmol (2001) 1.56
Mechanism of Theiler's virus-induced demyelination in nude mice. Lab Invest (1986) 1.53
Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3. Proc Natl Acad Sci U S A (1991) 1.52
Percutaneous balloon valvuloplasty for treatment of congenital pulmonary valvular stenosis in children. J Am Coll Cardiol (1984) 1.52
Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1. Gene (2001) 1.51
THE FILTRATION RATE, EFFECTIVE RENAL BLOOD FLOW, TUBULAR EXCRETORY MASS AND PHENOL RED CLEARANCE IN NORMAL PREGNANCY. J Clin Invest (1942) 1.50
Acute hemodynamic effects of captopril in children with a congestive or restrictive cardiomyopathy. Circulation (1991) 1.47
Rapid progression of prostate cancer in men with a BRCA2 mutation. Br J Cancer (2008) 1.45
Solid-phase methods for sequencing of nucleic acids I. Simultaneous sequencing of different oligodeoxyribonucleotides using a new, mechanically stable anion-exchange paper. Nucleic Acids Res (1985) 1.44
A translocation breakpoint cluster disrupts the newly defined 3' end of the SNURF-SNRPN transcription unit on chromosome 15. Hum Mol Genet (2001) 1.44
Genome sequence of bovine herpesvirus 4, a bovine Rhadinovirus, and identification of an origin of DNA replication. J Virol (2001) 1.44
Specification of dopaminergic and serotonergic neurons in the vertebrate CNS. Curr Opin Neurobiol (1999) 1.43
Increased MHC H-2K gene transcription in cultured mouse embryo cells after adenovirus infection. Nature (1985) 1.41
Gli regulation by the opposing activities of fused and suppressor of fused. Nat Cell Biol (2000) 1.41
Deletions of fetal and adult muscle cDNA in Duchenne and Becker muscular dystrophy patients. EMBO J (1987) 1.40
Interaction of EcoRII restriction and modification enzymes with synthetic DNA fragments. VI. The binding and cleavage of substrates containing nucleotide analogs. Nucleic Acids Res (1985) 1.40
Isolation of Plasmodium berghei (malaria) parasites by ammonium chloride lysis of infected erythrocytes. Nat New Biol (1971) 1.38
Characterization of two patched receptors for the vertebrate hedgehog protein family. Proc Natl Acad Sci U S A (1998) 1.38
Transient atrioventricular block resulting from left ventricular angiography in infants with ventricular septal defect. Am J Cardiol (1989) 1.37