R Woodgate

Author PubWeight™ 117.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Y-family of DNA polymerases. Mol Cell 2001 6.49
2 Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Cell 2001 5.93
3 Identification of additional genes belonging to the LexA regulon in Escherichia coli. Mol Microbiol 2000 5.08
4 UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V. Proc Natl Acad Sci U S A 1999 4.24
5 The Saccharomyces cerevisiae RAD30 gene, a homologue of Escherichia coli dinB and umuC, is DNA damage inducible and functions in a novel error-free postreplication repair mechanism. Genetics 1997 4.04
6 Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis. Nature 2000 3.95
7 UmuD mutagenesis protein of Escherichia coli: overproduction, purification, and cleavage by RecA. Proc Natl Acad Sci U S A 1988 3.85
8 Molecular analysis of antibiotic resistance gene clusters in vibrio cholerae O139 and O1 SXT constins. Antimicrob Agents Chemother 2001 3.10
9 poliota, a remarkably error-prone human DNA polymerase. Genes Dev 2000 3.08
10 Mutagenic repair in Escherichia coli: products of the recA gene and of the umuD and umuC genes act at different steps in UV-induced mutagenesis. Proc Natl Acad Sci U S A 1985 2.54
11 Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic poleta. Nucleic Acids Res 2001 2.29
12 Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein. Proc Natl Acad Sci U S A 1998 2.22
13 Eukaryotic DNA polymerases: proposal for a revised nomenclature. J Biol Chem 2001 2.15
14 Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta. Genomics 1999 2.06
15 Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Proc Natl Acad Sci U S A 1992 2.03
16 Regulation of SOS mutagenesis by proteolysis. Proc Natl Acad Sci U S A 1996 1.84
17 A rapid method for cloning mutagenic DNA repair genes: isolation of umu-complementing genes from multidrug resistance plasmids R391, R446b, and R471a. J Bacteriol 1993 1.75
18 Targeting of the UmuD, UmuD', and MucA' mutagenesis proteins to DNA by RecA protein. Proc Natl Acad Sci U S A 1993 1.75
19 Lon-mediated proteolysis of the Escherichia coli UmuD mutagenesis protein: in vitro degradation and identification of residues required for proteolysis. Genes Dev 1998 1.73
20 A phenotype for enigmatic DNA polymerase II: a pivotal role for pol II in replication restart in UV-irradiated Escherichia coli. Proc Natl Acad Sci U S A 1999 1.69
21 Structure of the UmuD' protein and its regulation in response to DNA damage. Nature 1996 1.66
22 Purification of a soluble UmuD'C complex from Escherichia coli. Cooperative binding of UmuD'C to single-stranded DNA. J Biol Chem 1996 1.64
23 Subunit-specific degradation of the UmuD/D' heterodimer by the ClpXP protease: the role of trans recognition in UmuD' stability. EMBO J 2000 1.64
24 Mutagenic repair in Escherichia coli. X. The umuC gene product may be required for replication past pyrimidine dimers but not for the coding error in UV-mutagenesis. Mol Gen Genet 1984 1.62
25 Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricus. Mutat Res 1996 1.61
26 The Bacillus subtilis DinR binding site: redefinition of the consensus sequence. J Bacteriol 1998 1.61
27 Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iota. EMBO J 2000 1.56
28 5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro. Science 2001 1.55
29 Formation of chromosomal tandem arrays of the SXT element and R391, two conjugative chromosomally integrating elements that share an attachment site. J Bacteriol 2001 1.55
30 A model for SOS-lesion-targeted mutations in Escherichia coli. Nature 2001 1.41
31 Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines. EMBO J 2001 1.36
32 Substitution of mucAB or rumAB for umuDC alters the relative frequencies of the two classes of mutations induced by a site-specific T-T cyclobutane dimer and the efficiency of translesion DNA synthesis. J Bacteriol 1996 1.29
33 Roles of DNA polymerases V and II in SOS-induced error-prone and error-free repair in Escherichia coli. Proc Natl Acad Sci U S A 2001 1.27
34 The two-step model of bacterial UV mutagenesis. Mutat Res 1985 1.25
35 In vivo stability of the Umu mutagenesis proteins: a major role for RecA. J Bacteriol 1996 1.25
36 Characterization of the umu-complementing operon from R391. J Bacteriol 1995 1.22
37 Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template. EMBO J 2001 1.22
38 Intermolecular cleavage by UmuD-like mutagenesis proteins. Proc Natl Acad Sci U S A 1998 1.21
39 Characterization of DinR, the Bacillus subtilis SOS repressor. J Bacteriol 1997 1.18
40 Mutagenic DNA repair in Escherichia coli. XIII. Proofreading exonuclease of DNA polymerase III holoenzyme is not operational during UV mutagenesis. Mutat Res 1987 1.16
41 Analysis of recA mutants with altered SOS functions. Mutat Res 1995 1.11
42 Human DNA polymerase iota promiscuous mismatch extension. J Biol Chem 2001 1.10
43 Intermolecular cleavage by UmuD-like enzymes: identification of residues required for cleavage and substrate specificity. J Mol Biol 1999 1.09
44 Escherichia coli umuDC mutants: DNA sequence alterations and UmuD cleavage. Mol Gen Genet 1992 1.09
45 Genetic analysis of the mobilization and leading regions of the IncN plasmids pKM101 and pCU1. J Bacteriol 1999 1.09
46 DNA polymerase iota and related rad30-like enzymes. Philos Trans R Soc Lond B Biol Sci 2001 1.08
47 The enhanced mutagenic potential of the MucAB proteins correlates with the highly efficient processing of the MucA protein. J Bacteriol 1992 1.06
48 Mutagenic DNA repair in enterobacteria. J Bacteriol 1991 1.04
49 Efficient translesion replication in the absence of Escherichia coli Umu proteins and 3'-5' exonuclease proofreading function. Proc Natl Acad Sci U S A 1998 1.02
50 The UmuD' protein filament and its potential role in damage induced mutagenesis. Structure 1996 1.01
51 Modulation of RecA nucleoprotein function by the mutagenic UmuD'C protein complex. J Biol Chem 1998 1.01
52 Mutagenic DNA repair in Escherichia coli, XX. Overproduction of UmuD' protein results in suppression of the umuC36 mutation in excision defective bacteria. Mutat Res 1991 0.99
53 Unusual insertion element polymorphisms in the promoter and terminator regions of the mucAB-like genes of R471a and R446b. Mutat Res 1998 0.96
54 Visualization of two binding sites for the Escherichia coli UmuD'(2)C complex (DNA pol V) on RecA-ssDNA filaments. J Mol Biol 2000 0.95
55 New role for photoreversible pyrimidine dimers in induction of prototrophic mutations in excision-deficient Escherichia coli by UV light. J Bacteriol 1986 0.94
56 Analysis of the mutagenic properties of the UmuDC, MucAB and RumAB proteins, using a site-specific abasic lesion. Mol Gen Genet 1996 0.92
57 Novel Escherichia coli umuD' mutants: structure-function insights into SOS mutagenesis. J Bacteriol 1998 0.89
58 Enhanced generation of A:T-->T:A transversions in a recA730 lexA51(Def) mutant of Escherichia coli. Mutat Res 1997 0.89
59 The biochemical basis and in vivo regulation of SOS-induced mutagenesis promoted by Escherichia coli DNA polymerase V (UmuD'2C). Cold Spring Harb Symp Quant Biol 2000 0.88
60 The bacteriophage P1 HumD protein is a functional homolog of the prokaryotic UmuD'-like proteins and facilitates SOS mutagenesis in Escherichia coli. J Bacteriol 1999 0.87
61 Arrested DNA replication in Xenopus and release by Escherichia coli mutagenesis proteins. Science 1996 0.85
62 Regulation of UmuD cleavage: role of the amino-terminal tail. J Mol Biol 1998 0.85
63 Intrinsic polymerase activities of UmuD'(2)C and MucA'(2)B are responsible for their different mutagenic properties during bypass of a T-T cis-syn cyclobutane dimer. J Bacteriol 2000 0.85
64 Effects of the absence of protozoa from birth or from weaning on the growth and methane production of lambs. Br J Nutr 2008 0.85
65 Structural insights into the regulation of SOS mutagenesis. Acta Biochim Pol 1998 0.84
66 Biochemical characterization of human DNA polymerase iota provides clues to its biological function. Biochem Soc Trans 2001 0.83
67 Identification of mucAB-like homologs on two IncT plasmids, R394 and Rts-1. Mutat Res 2000 0.82
68 Current understanding of UV-induced base pair substitution mutation in E. coli with particular reference to the DNA polymerase III complex. Mutat Res 1987 0.82
69 Analysis of chimeric UmuC proteins: identification of regions in Salmonella typhimurium UmuC important for mutagenic activity. Mol Gen Genet 1996 0.78
70 Selective inhibition of RecA functions by the Hc1 nucleoid condensation protein from Chlamydia trachomatis. FEMS Microbiol Lett 2000 0.76
71 Perceptions of the role of the school in providing information and support to adolescent children of women with breast cancer. J Adv Nurs 2000 0.75
72 [Pain management in children]. Pflege Aktuell 2000 0.75
73 Haemolytic anaemia associated with Theileria sp. in an orphaned platypus. Aust Vet J 2014 0.75
74 Production and crystallization of a selenomethionyl variant of UmuD', an Escherichia coli SOS response protein. Proteins 1996 0.75