| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease.
|
Nature
|
2001
|
33.12
|
|
2
|
Mapping of a susceptibility locus for Crohn's disease on chromosome 16.
|
Nature
|
1996
|
5.44
|
|
3
|
Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study.
|
Br J Cancer
|
2001
|
5.36
|
|
4
|
Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients.
|
Cell
|
1993
|
2.31
|
|
5
|
Association of p53 mutations with short survival in colorectal cancer.
|
Gastroenterology
|
1994
|
2.19
|
|
6
|
Hepatitis C virus genotyping by means of 5'-UR/core line probe assays and molecular analysis of untypeable samples.
|
Virus Res
|
1995
|
2.14
|
|
7
|
BRCA1 sequence variations in 160 individuals referred to a breast/ovarian family cancer clinic. Institut Curie Breast Cancer Group.
|
Am J Hum Genet
|
1997
|
1.91
|
|
8
|
Alternative genetic pathways in colorectal carcinogenesis.
|
Proc Natl Acad Sci U S A
|
1997
|
1.68
|
|
9
|
The prevalence of colonic polyps in acromegaly: a colonoscopic and pathological study in 103 patients.
|
J Clin Endocrinol Metab
|
1995
|
1.68
|
|
10
|
Detection of plasma tumor DNA in head and neck squamous cell carcinoma by microsatellite typing and p53 mutation analysis.
|
Cancer Res
|
2000
|
1.63
|
|
11
|
Germ-line mutations in the first 14 exons of the adenomatous polyposis coli (APC) gene.
|
Am J Hum Genet
|
1993
|
1.53
|
|
12
|
TP53 gene mutations and p53 protein immunoreactivity in malignant and premalignant Barrett's esophagus.
|
Gastroenterology
|
1994
|
1.50
|
|
13
|
Oncogenic mutations as predictive factors in colorectal cancer.
|
Oncogene
|
2010
|
1.45
|
|
14
|
Performance of office hysteroscopy and endometrial biopsy for detecting endometrial disease in women at risk of human non-polyposis colon cancer: a prospective study.
|
Int J Gynecol Cancer
|
2008
|
1.43
|
|
15
|
Analysis of p53 antibodies in patients with various cancers define B-cell epitopes of human p53: distribution on primary structure and exposure on protein surface.
|
Cancer Res
|
1993
|
1.41
|
|
16
|
p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series.
|
J Clin Oncol
|
2000
|
1.39
|
|
17
|
Screening for germ-line mutations in the NF2 gene.
|
Genes Chromosomes Cancer
|
1995
|
1.35
|
|
18
|
Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status.
|
Br J Cancer
|
2000
|
1.32
|
|
19
|
Influence of epidermal growth factor receptor (EGFR), p53 and intrinsic MAP kinase pathway status of tumour cells on the antiproliferative effect of ZD1839 ("Iressa").
|
Br J Cancer
|
2002
|
1.29
|
|
20
|
Beta-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity.
|
Oncogene
|
1999
|
1.22
|
|
21
|
Polymerase chain reaction assay for the detection of Helicobacter pylori in gastric biopsy specimens: comparison with culture, rapid urease test, and histopathological tests.
|
Gut
|
1994
|
1.19
|
|
22
|
Determination of microsatellite instability, p53 and K-RAS mutations in hepatic metastases from patients with colorectal cancer: relationship with response to 5-fluorouracil and survival.
|
Int J Cancer
|
2001
|
1.18
|
|
23
|
Evidence of linkage of the inflammatory bowel disease susceptibility locus on chromosome 16 (IBD1) to ulcerative colitis.
|
J Med Genet
|
1998
|
1.17
|
|
24
|
Panitumumab combined with irinotecan for patients with KRAS wild-type metastatic colorectal cancer refractory to standard chemotherapy: a GERCOR efficacy, tolerance, and translational molecular study.
|
Ann Oncol
|
2012
|
1.14
|
|
25
|
Increased p53 protein content of colorectal tumours correlates with poor survival.
|
Br J Cancer
|
1992
|
1.13
|
|
26
|
Polymorphisms and probable lack of mutation in the WAF1-CIP1 gene in colorectal cancer.
|
Oncogene
|
1995
|
1.12
|
|
27
|
Mutational analysis of the PTEN gene in gliomas: molecular and pathological correlations.
|
Int J Cancer
|
1999
|
1.09
|
|
28
|
Serological determination of hepatitis C virus genotype: comparison with a standardized genotyping assay.
|
J Clin Microbiol
|
1997
|
1.07
|
|
29
|
Efficient screening of p53 mutations by denaturing gradient gel electrophoresis in colorectal tumors.
|
Oncogene
|
1993
|
1.07
|
|
30
|
Simultaneous monitoring of P53 protein and DNA content of colorectal adenocarcinomas by flow cytometry.
|
Int J Cancer
|
1990
|
1.07
|
|
31
|
Concerted nonsyntenic allelic losses in hyperploid hepatocellular carcinoma as determined by a high-resolution allelotype.
|
Cancer Res
|
1997
|
1.07
|
|
32
|
Human fibulin-4: analysis of its biosynthetic processing and mRNA expression in normal and tumour tissues.
|
FEBS Lett
|
2001
|
1.07
|
|
33
|
Germline mutation profile of the VHL gene in von Hippel-Lindau disease and in sporadic hemangioblastoma.
|
Hum Mutat
|
1998
|
1.07
|
|
34
|
Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity.
|
Br J Cancer
|
2004
|
1.06
|
|
35
|
Chronic endogenous hypergastrinemia in humans: evidence for a mitogenic effect on the colonic mucosa.
|
Gastroenterology
|
1993
|
1.04
|
|
36
|
Expression and mutational status of treatment-relevant targets and key oncogenes in 123 malignant salivary gland tumours.
|
Ann Oncol
|
2013
|
1.03
|
|
37
|
Linkage analyses of chromosome 6 loci, including HLA, in familial aggregations of Crohn disease. G.E.T.A.I.D.
|
Am J Med Genet
|
1994
|
1.02
|
|
38
|
Glutathione-associated enzymes in head and neck squamous cell carcinoma and response to cisplatin-based neoadjuvant chemotherapy.
|
Int J Cancer
|
2001
|
1.01
|
|
39
|
Circulating free tumor DNA and colorectal cancer.
|
Gastroenterol Clin Biol
|
2010
|
0.98
|
|
40
|
Frequent allelic loss at chromosome 3p distinct from genetic alterations of the 8-oxoguanine DNA glycosylase 1 gene in head and neck cancer.
|
Mol Carcinog
|
1999
|
0.93
|
|
41
|
Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study.
|
Br J Cancer
|
2013
|
0.92
|
|
42
|
An alternative to prophylactic colectomy for colon cancer prevention in HNPCC syndrome.
|
Gut
|
2005
|
0.91
|
|
43
|
[Semi-automated quantitative method for detecting the loss of heterozygosity at the long arm of chromosome 4 in hepatocellular carcinoma].
|
Gastroenterol Clin Biol
|
1999
|
0.90
|
|
44
|
Clinicopathological significance of mitochondrial D-Loop mutations in head and neck carcinoma.
|
Br J Cancer
|
2006
|
0.89
|
|
45
|
Enhanced detection of antibodies to hepatitis C virus by use of a third-generation recombinant immunoblot assay.
|
J Med Virol
|
1994
|
0.89
|
|
46
|
Prognostic influence of clinicopathologic features, DNA-ploidy, CD44H and p53 expression in a large series of resected hepatocellular carcinoma in France.
|
Int J Cancer
|
1997
|
0.88
|
|
47
|
Hepatitis C virus infection in pediatric liver transplantation.
|
Transplantation
|
1993
|
0.86
|
|
48
|
Is the multiple endocrine neoplasia type 1 gene a suppressor for fundic argyrophil tumors in the Zollinger-Ellison syndrome?
|
Gastroenterology
|
1993
|
0.84
|
|
49
|
Qualitative gene profiling: a novel tool in genomics and in pharmacogenomics that deciphers messenger RNA isoforms diversity.
|
Pharmacogenomics
|
2000
|
0.83
|
|
50
|
[Technical considerations for KRAS testing in colorectal cancer. The biologist's point of view].
|
Bull Cancer
|
2009
|
0.82
|
|
51
|
Indeterminate third-generation recombinant immunoblot assay in hepatitis C virus infection. Group d'Etudes Moléculaires des Hépatites (GEMHEP).
|
J Hepatol
|
1994
|
0.82
|
|
52
|
Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population.
|
Hum Genet
|
1991
|
0.81
|
|
53
|
Somatically acquired genetic alterations in flat colorectal neoplasias.
|
Int J Cancer
|
1998
|
0.81
|
|
54
|
Frequent polymorphism in the 13th exon of the adenomatous polyposis coli gene.
|
Hum Genet
|
1992
|
0.81
|
|
55
|
UDP-glucuronosyltransferase UGT1A7 genetic polymorphisms in hepatocellular carcinoma: a differential impact according to seropositivity of HBV or HCV markers?
|
BMC Cancer
|
2007
|
0.80
|
|
56
|
Polymorphisms of human aryl hydrocarbon receptor (AhR) gene in a French population: relationship with CYP1A1 inducibility and lung cancer.
|
Carcinogenesis
|
2001
|
0.80
|
|
57
|
Genetic characterization of the APC locus involved in familial adenomatous polyposis.
|
Gastroenterology
|
1991
|
0.80
|
|
58
|
[Localization of a tumor suppressor gene distal to D22S270 in colorectal cancers].
|
Gastroenterol Clin Biol
|
1997
|
0.80
|
|
59
|
Deletion mapping of the tumor suppressor locus involved in colorectal cancer on chromosome band 8p21.
|
Genes Chromosomes Cancer
|
1999
|
0.80
|
|
60
|
Topoisomerase I-DNA covalent complexes in human colorectal cancer xenografts with different p53 and microsatellite instability status: relation with their sensitivity to CTP-11.
|
Anticancer Res
|
2001
|
0.80
|
|
61
|
Detection by DGGE of a new polymorphism closely linked to the adenomatous polyposis coli region.
|
Hum Genet
|
1992
|
0.79
|
|
62
|
Segregation of two BRCA1 mutations in a single family.
|
Am J Hum Genet
|
1996
|
0.79
|
|
63
|
PCR-based genotyping can generate artifacts in LOH analyses.
|
Biotechniques
|
1999
|
0.78
|
|
64
|
A high hepatitis E virus seroprevalence among renal transplantation and haemophilia patient populations.
|
J Hepatol
|
1996
|
0.78
|
|
65
|
[Cellular and neoplastic otorhinolaryngologic changes, molecular markers and therapeutic potential].
|
Ann Otolaryngol Chir Cervicofac
|
2003
|
0.78
|
|
66
|
High resolution genetic map of the adenomatous polyposis coli gene (APC) region.
|
Am J Med Genet
|
1995
|
0.78
|
|
67
|
Microsatellite analysis and response to chemotherapy in head-and-neck squamous-cell carcinoma.
|
Int J Cancer
|
1999
|
0.77
|
|
68
|
Prevalence of hepatitis C virus RNA in suspected drug induced liver diseases.
|
J Hepatol
|
1993
|
0.77
|
|
69
|
Influence of cirrhosis on lamotrigine pharmacokinetics.
|
Br J Clin Pharmacol
|
2001
|
0.77
|
|
70
|
[Molecular biology in clinical cancer research: the example of digestive cancers].
|
Rev Epidemiol Sante Publique
|
2005
|
0.77
|
|
71
|
Transcription of SST2 somatostatin receptor gene in human pancreatic cancer cells is altered by single nucleotide promoter polymorphism.
|
Gastroenterology
|
2001
|
0.77
|
|
72
|
Prevalence of anti-hepatitis C virus antibodies among patients with alcoholic liver disease, supplemented by 4-RIBA.
|
Dig Dis Sci
|
1992
|
0.77
|
|
73
|
Analysis of sera indeterminate by Ortho-HCV RIBA-2 by using three confirmatory assays for anti-hepatitis C virus antibody.
|
J Clin Microbiol
|
1994
|
0.77
|
|
74
|
No evidence for germline PTEN mutations in families with breast and brain tumours.
|
Int J Cancer
|
1999
|
0.77
|
|
75
|
[APC protein: protein interactions and cellular functions].
|
Gastroenterol Clin Biol
|
1998
|
0.76
|
|
76
|
Association of a duodenal follicular lymphoma and hereditary nonpolyposis colorectal cancer.
|
Mod Pathol
|
2000
|
0.76
|
|
77
|
Mitochondrial aspartate aminotransferase in nonalcoholic cirrhosis.
|
Gastroenterology
|
1989
|
0.76
|
|
78
|
Lipase/amylase ratio in pancreatitis: an etiologic index?
|
Gastroenterology
|
1992
|
0.75
|
|
79
|
Thymidylate synthase promoter polymorphism.
|
J Clin Oncol
|
2001
|
0.75
|
|
80
|
[Genetic heterogeneity of certain sporadic colorectal cancers].
|
Gastroenterol Clin Biol
|
1993
|
0.75
|
|
81
|
[Strategy of screening for patients at high risk of colorectal neoplasm].
|
Gastroenterol Clin Biol
|
1998
|
0.75
|
|
82
|
[To study protein p53. Why, how?].
|
Ann Pathol
|
1995
|
0.75
|
|
83
|
Chromosome 12 alterations and c-Ki-ras mutations in colorectal tumors.
|
Cancer Genet Cytogenet
|
1993
|
0.75
|
|
84
|
[Bullous pemphigoid secondary corticoresistant. Inhibitory role of omeprazole on corticosteroid metabolism?].
|
Ann Dermatol Venereol
|
1991
|
0.75
|
|
85
|
Fatal reactivation of hepatitis B virus mutant following cytotoxic treatment.
|
J Hepatol
|
1994
|
0.75
|
|
86
|
A case of cholestasis: benign and recurrent and not due to measles.
|
JAMA
|
1989
|
0.75
|
|
87
|
[p53 and colorectal cancer].
|
Pathol Biol (Paris)
|
1997
|
0.75
|
|
88
|
[Inflammatory bowel diseases: genetic hypothesis].
|
Acta Gastroenterol Belg
|
1995
|
0.75
|
|
89
|
[Lynch syndrome: towards a multidisciplinary management of tumour screening].
|
Gynecol Obstet Fertil
|
2011
|
0.75
|
|
90
|
[Genetics of inflammatory bowel diseases].
|
Gastroenterol Clin Biol
|
1995
|
0.75
|
|
91
|
[Colonic angiodysplasia. An apple of medicosurgical discord].
|
Presse Med
|
1987
|
0.75
|
|
92
|
[Toxoplasmosis and mediastinal adenopathies. A reality?].
|
Presse Med
|
1987
|
0.75
|
|
93
|
[Genetic alterations in hepatocellular carcinomas: associations with clinical parameters].
|
Gastroenterol Clin Biol
|
2001
|
0.75
|
|
94
|
[Hepatic lipogranulomatosis and lipoid pneumopathy].
|
Gastroenterol Clin Biol
|
1989
|
0.75
|
|
95
|
[Genetic alterations associated with hepatocellular carcinoma].
|
Gastroenterol Clin Biol
|
1997
|
0.75
|
|
96
|
[HNPCC syndrome (hereditary non polyposis colon cancer): identification and management].
|
Rev Med Interne
|
2005
|
0.75
|
|
97
|
[Tumor suppressor genes in cancers of colon and rectum].
|
Rev Prat
|
1991
|
0.75
|
|
98
|
[Psoriatic arthritis in a patient treated with interferon alpha].
|
Rev Rhum Ed Fr
|
1993
|
0.75
|
|
99
|
Association of serum antibodies against p53 protein with poor survival in patients with Zollinger-Ellison syndrome.
|
Gastroenterology
|
1998
|
0.75
|
|
100
|
[Analysis of genetic disorders of cancer of the rectum: differences in relation to cancer of the colon].
|
Gastroenterol Clin Biol
|
1998
|
0.75
|
|
101
|
[Familial adenomatous polyposis: early diagnosis by genetic mapping].
|
Gastroenterol Clin Biol
|
1992
|
0.75
|
|
102
|
[Diffusion of cefpirome in ascitic fluid].
|
Gastroenterol Clin Biol
|
1993
|
0.75
|
|
103
|
[Genetic transmission of colorectal adenomas].
|
Presse Med
|
1991
|
0.75
|
|
104
|
[P53 protein: a new tool for the clinician?].
|
Gastroenterol Clin Biol
|
1995
|
0.75
|
|
105
|
[Contributions of genetics in gastroenterology. Has genetic progress changed the therapeutic management of colorectal neoplasms? "Colon" Group of the Curie Institute].
|
Chirurgie
|
1998
|
0.75
|
|
106
|
[Malnutrition in chronic radiation enteritis. Study of 100 patients].
|
Ann Gastroenterol Hepatol (Paris)
|
1988
|
0.75
|
|
107
|
[Identification and management of HNPCC syndrome (hereditary non polyposis colon cancer), hereditary predisposition to colorectal and endometrial adenocarcinomas].
|
Pathol Biol (Paris)
|
2006
|
0.75
|
|
108
|
[Endometrial cancer in HNPCC syndrome].
|
J Gynecol Obstet Biol Reprod (Paris)
|
2008
|
0.75
|
|
109
|
[Caustic esophago-gastric and liver lesions caused by ingestion of a plastic resin hardener].
|
Gastroenterol Clin Biol
|
1991
|
0.75
|
|
110
|
[Gene TP53 and digestive cancers].
|
Gastroenterol Clin Biol
|
1993
|
0.75
|
|
111
|
[Pseudohyperchloremia disclosing bromide poisoning].
|
Presse Med
|
1986
|
0.75
|
|
112
|
[Biological diagnosis of hepatitis C virus infection. Role of serological and molecular tests].
|
Gastroenterol Clin Biol
|
1996
|
0.75
|
|
113
|
[Molecular techniques in the detection of colorectal cancer].
|
Gastroenterol Clin Biol
|
1997
|
0.75
|