P Laurent-Puig

Author PubWeight™ 121.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001 33.12
2 Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 1996 5.44
3 Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study. Br J Cancer 2001 5.36
4 Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients. Cell 1993 2.31
5 Association of p53 mutations with short survival in colorectal cancer. Gastroenterology 1994 2.19
6 Hepatitis C virus genotyping by means of 5'-UR/core line probe assays and molecular analysis of untypeable samples. Virus Res 1995 2.14
7 BRCA1 sequence variations in 160 individuals referred to a breast/ovarian family cancer clinic. Institut Curie Breast Cancer Group. Am J Hum Genet 1997 1.91
8 Alternative genetic pathways in colorectal carcinogenesis. Proc Natl Acad Sci U S A 1997 1.68
9 The prevalence of colonic polyps in acromegaly: a colonoscopic and pathological study in 103 patients. J Clin Endocrinol Metab 1995 1.68
10 Detection of plasma tumor DNA in head and neck squamous cell carcinoma by microsatellite typing and p53 mutation analysis. Cancer Res 2000 1.63
11 Germ-line mutations in the first 14 exons of the adenomatous polyposis coli (APC) gene. Am J Hum Genet 1993 1.53
12 TP53 gene mutations and p53 protein immunoreactivity in malignant and premalignant Barrett's esophagus. Gastroenterology 1994 1.50
13 Oncogenic mutations as predictive factors in colorectal cancer. Oncogene 2010 1.45
14 Performance of office hysteroscopy and endometrial biopsy for detecting endometrial disease in women at risk of human non-polyposis colon cancer: a prospective study. Int J Gynecol Cancer 2008 1.43
15 Analysis of p53 antibodies in patients with various cancers define B-cell epitopes of human p53: distribution on primary structure and exposure on protein surface. Cancer Res 1993 1.41
16 p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series. J Clin Oncol 2000 1.39
17 Screening for germ-line mutations in the NF2 gene. Genes Chromosomes Cancer 1995 1.35
18 Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status. Br J Cancer 2000 1.32
19 Influence of epidermal growth factor receptor (EGFR), p53 and intrinsic MAP kinase pathway status of tumour cells on the antiproliferative effect of ZD1839 ("Iressa"). Br J Cancer 2002 1.29
20 Beta-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity. Oncogene 1999 1.22
21 Polymerase chain reaction assay for the detection of Helicobacter pylori in gastric biopsy specimens: comparison with culture, rapid urease test, and histopathological tests. Gut 1994 1.19
22 Determination of microsatellite instability, p53 and K-RAS mutations in hepatic metastases from patients with colorectal cancer: relationship with response to 5-fluorouracil and survival. Int J Cancer 2001 1.18
23 Evidence of linkage of the inflammatory bowel disease susceptibility locus on chromosome 16 (IBD1) to ulcerative colitis. J Med Genet 1998 1.17
24 Panitumumab combined with irinotecan for patients with KRAS wild-type metastatic colorectal cancer refractory to standard chemotherapy: a GERCOR efficacy, tolerance, and translational molecular study. Ann Oncol 2012 1.14
25 Increased p53 protein content of colorectal tumours correlates with poor survival. Br J Cancer 1992 1.13
26 Polymorphisms and probable lack of mutation in the WAF1-CIP1 gene in colorectal cancer. Oncogene 1995 1.12
27 Mutational analysis of the PTEN gene in gliomas: molecular and pathological correlations. Int J Cancer 1999 1.09
28 Serological determination of hepatitis C virus genotype: comparison with a standardized genotyping assay. J Clin Microbiol 1997 1.07
29 Efficient screening of p53 mutations by denaturing gradient gel electrophoresis in colorectal tumors. Oncogene 1993 1.07
30 Simultaneous monitoring of P53 protein and DNA content of colorectal adenocarcinomas by flow cytometry. Int J Cancer 1990 1.07
31 Concerted nonsyntenic allelic losses in hyperploid hepatocellular carcinoma as determined by a high-resolution allelotype. Cancer Res 1997 1.07
32 Human fibulin-4: analysis of its biosynthetic processing and mRNA expression in normal and tumour tissues. FEBS Lett 2001 1.07
33 Germline mutation profile of the VHL gene in von Hippel-Lindau disease and in sporadic hemangioblastoma. Hum Mutat 1998 1.07
34 Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity. Br J Cancer 2004 1.06
35 Chronic endogenous hypergastrinemia in humans: evidence for a mitogenic effect on the colonic mucosa. Gastroenterology 1993 1.04
36 Expression and mutational status of treatment-relevant targets and key oncogenes in 123 malignant salivary gland tumours. Ann Oncol 2013 1.03
37 Linkage analyses of chromosome 6 loci, including HLA, in familial aggregations of Crohn disease. G.E.T.A.I.D. Am J Med Genet 1994 1.02
38 Glutathione-associated enzymes in head and neck squamous cell carcinoma and response to cisplatin-based neoadjuvant chemotherapy. Int J Cancer 2001 1.01
39 Circulating free tumor DNA and colorectal cancer. Gastroenterol Clin Biol 2010 0.98
40 Frequent allelic loss at chromosome 3p distinct from genetic alterations of the 8-oxoguanine DNA glycosylase 1 gene in head and neck cancer. Mol Carcinog 1999 0.93
41 Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study. Br J Cancer 2013 0.92
42 An alternative to prophylactic colectomy for colon cancer prevention in HNPCC syndrome. Gut 2005 0.91
43 [Semi-automated quantitative method for detecting the loss of heterozygosity at the long arm of chromosome 4 in hepatocellular carcinoma]. Gastroenterol Clin Biol 1999 0.90
44 Clinicopathological significance of mitochondrial D-Loop mutations in head and neck carcinoma. Br J Cancer 2006 0.89
45 Enhanced detection of antibodies to hepatitis C virus by use of a third-generation recombinant immunoblot assay. J Med Virol 1994 0.89
46 Prognostic influence of clinicopathologic features, DNA-ploidy, CD44H and p53 expression in a large series of resected hepatocellular carcinoma in France. Int J Cancer 1997 0.88
47 Hepatitis C virus infection in pediatric liver transplantation. Transplantation 1993 0.86
48 Is the multiple endocrine neoplasia type 1 gene a suppressor for fundic argyrophil tumors in the Zollinger-Ellison syndrome? Gastroenterology 1993 0.84
49 Qualitative gene profiling: a novel tool in genomics and in pharmacogenomics that deciphers messenger RNA isoforms diversity. Pharmacogenomics 2000 0.83
50 [Technical considerations for KRAS testing in colorectal cancer. The biologist's point of view]. Bull Cancer 2009 0.82
51 Indeterminate third-generation recombinant immunoblot assay in hepatitis C virus infection. Group d'Etudes Moléculaires des Hépatites (GEMHEP). J Hepatol 1994 0.82
52 Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population. Hum Genet 1991 0.81
53 Somatically acquired genetic alterations in flat colorectal neoplasias. Int J Cancer 1998 0.81
54 Frequent polymorphism in the 13th exon of the adenomatous polyposis coli gene. Hum Genet 1992 0.81
55 UDP-glucuronosyltransferase UGT1A7 genetic polymorphisms in hepatocellular carcinoma: a differential impact according to seropositivity of HBV or HCV markers? BMC Cancer 2007 0.80
56 Polymorphisms of human aryl hydrocarbon receptor (AhR) gene in a French population: relationship with CYP1A1 inducibility and lung cancer. Carcinogenesis 2001 0.80
57 Genetic characterization of the APC locus involved in familial adenomatous polyposis. Gastroenterology 1991 0.80
58 [Localization of a tumor suppressor gene distal to D22S270 in colorectal cancers]. Gastroenterol Clin Biol 1997 0.80
59 Deletion mapping of the tumor suppressor locus involved in colorectal cancer on chromosome band 8p21. Genes Chromosomes Cancer 1999 0.80
60 Topoisomerase I-DNA covalent complexes in human colorectal cancer xenografts with different p53 and microsatellite instability status: relation with their sensitivity to CTP-11. Anticancer Res 2001 0.80
61 Detection by DGGE of a new polymorphism closely linked to the adenomatous polyposis coli region. Hum Genet 1992 0.79
62 Segregation of two BRCA1 mutations in a single family. Am J Hum Genet 1996 0.79
63 PCR-based genotyping can generate artifacts in LOH analyses. Biotechniques 1999 0.78
64 A high hepatitis E virus seroprevalence among renal transplantation and haemophilia patient populations. J Hepatol 1996 0.78
65 [Cellular and neoplastic otorhinolaryngologic changes, molecular markers and therapeutic potential]. Ann Otolaryngol Chir Cervicofac 2003 0.78
66 High resolution genetic map of the adenomatous polyposis coli gene (APC) region. Am J Med Genet 1995 0.78
67 Microsatellite analysis and response to chemotherapy in head-and-neck squamous-cell carcinoma. Int J Cancer 1999 0.77
68 Prevalence of hepatitis C virus RNA in suspected drug induced liver diseases. J Hepatol 1993 0.77
69 Influence of cirrhosis on lamotrigine pharmacokinetics. Br J Clin Pharmacol 2001 0.77
70 [Molecular biology in clinical cancer research: the example of digestive cancers]. Rev Epidemiol Sante Publique 2005 0.77
71 Transcription of SST2 somatostatin receptor gene in human pancreatic cancer cells is altered by single nucleotide promoter polymorphism. Gastroenterology 2001 0.77
72 Prevalence of anti-hepatitis C virus antibodies among patients with alcoholic liver disease, supplemented by 4-RIBA. Dig Dis Sci 1992 0.77
73 Analysis of sera indeterminate by Ortho-HCV RIBA-2 by using three confirmatory assays for anti-hepatitis C virus antibody. J Clin Microbiol 1994 0.77
74 No evidence for germline PTEN mutations in families with breast and brain tumours. Int J Cancer 1999 0.77
75 [APC protein: protein interactions and cellular functions]. Gastroenterol Clin Biol 1998 0.76
76 Association of a duodenal follicular lymphoma and hereditary nonpolyposis colorectal cancer. Mod Pathol 2000 0.76
77 Mitochondrial aspartate aminotransferase in nonalcoholic cirrhosis. Gastroenterology 1989 0.76
78 Lipase/amylase ratio in pancreatitis: an etiologic index? Gastroenterology 1992 0.75
79 Thymidylate synthase promoter polymorphism. J Clin Oncol 2001 0.75
80 [Genetic heterogeneity of certain sporadic colorectal cancers]. Gastroenterol Clin Biol 1993 0.75
81 [Strategy of screening for patients at high risk of colorectal neoplasm]. Gastroenterol Clin Biol 1998 0.75
82 [To study protein p53. Why, how?]. Ann Pathol 1995 0.75
83 Chromosome 12 alterations and c-Ki-ras mutations in colorectal tumors. Cancer Genet Cytogenet 1993 0.75
84 [Bullous pemphigoid secondary corticoresistant. Inhibitory role of omeprazole on corticosteroid metabolism?]. Ann Dermatol Venereol 1991 0.75
85 Fatal reactivation of hepatitis B virus mutant following cytotoxic treatment. J Hepatol 1994 0.75
86 A case of cholestasis: benign and recurrent and not due to measles. JAMA 1989 0.75
87 [p53 and colorectal cancer]. Pathol Biol (Paris) 1997 0.75
88 [Inflammatory bowel diseases: genetic hypothesis]. Acta Gastroenterol Belg 1995 0.75
89 [Lynch syndrome: towards a multidisciplinary management of tumour screening]. Gynecol Obstet Fertil 2011 0.75
90 [Genetics of inflammatory bowel diseases]. Gastroenterol Clin Biol 1995 0.75
91 [Colonic angiodysplasia. An apple of medicosurgical discord]. Presse Med 1987 0.75
92 [Toxoplasmosis and mediastinal adenopathies. A reality?]. Presse Med 1987 0.75
93 [Genetic alterations in hepatocellular carcinomas: associations with clinical parameters]. Gastroenterol Clin Biol 2001 0.75
94 [Hepatic lipogranulomatosis and lipoid pneumopathy]. Gastroenterol Clin Biol 1989 0.75
95 [Genetic alterations associated with hepatocellular carcinoma]. Gastroenterol Clin Biol 1997 0.75
96 [HNPCC syndrome (hereditary non polyposis colon cancer): identification and management]. Rev Med Interne 2005 0.75
97 [Tumor suppressor genes in cancers of colon and rectum]. Rev Prat 1991 0.75
98 [Psoriatic arthritis in a patient treated with interferon alpha]. Rev Rhum Ed Fr 1993 0.75
99 Association of serum antibodies against p53 protein with poor survival in patients with Zollinger-Ellison syndrome. Gastroenterology 1998 0.75
100 [Analysis of genetic disorders of cancer of the rectum: differences in relation to cancer of the colon]. Gastroenterol Clin Biol 1998 0.75
101 [Familial adenomatous polyposis: early diagnosis by genetic mapping]. Gastroenterol Clin Biol 1992 0.75
102 [Diffusion of cefpirome in ascitic fluid]. Gastroenterol Clin Biol 1993 0.75
103 [Genetic transmission of colorectal adenomas]. Presse Med 1991 0.75
104 [P53 protein: a new tool for the clinician?]. Gastroenterol Clin Biol 1995 0.75
105 [Contributions of genetics in gastroenterology. Has genetic progress changed the therapeutic management of colorectal neoplasms? "Colon" Group of the Curie Institute]. Chirurgie 1998 0.75
106 [Malnutrition in chronic radiation enteritis. Study of 100 patients]. Ann Gastroenterol Hepatol (Paris) 1988 0.75
107 [Identification and management of HNPCC syndrome (hereditary non polyposis colon cancer), hereditary predisposition to colorectal and endometrial adenocarcinomas]. Pathol Biol (Paris) 2006 0.75
108 [Endometrial cancer in HNPCC syndrome]. J Gynecol Obstet Biol Reprod (Paris) 2008 0.75
109 [Caustic esophago-gastric and liver lesions caused by ingestion of a plastic resin hardener]. Gastroenterol Clin Biol 1991 0.75
110 [Gene TP53 and digestive cancers]. Gastroenterol Clin Biol 1993 0.75
111 [Pseudohyperchloremia disclosing bromide poisoning]. Presse Med 1986 0.75
112 [Biological diagnosis of hepatitis C virus infection. Role of serological and molecular tests]. Gastroenterol Clin Biol 1996 0.75
113 [Molecular techniques in the detection of colorectal cancer]. Gastroenterol Clin Biol 1997 0.75