Is there a relationship between rheumatoid arthritis and periodontal disease?

Periodontitis in systemic rheumatic diseases. Nat Rev Rheumatol (2009) 2.14

Hypothesis: the humoral immune response to oral bacteria provides a stimulus for the development of rheumatoid arthritis. Inflammation (2004) 1.97

Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis. Int Immunopharmacol (2008) 1.79

Novel host response therapeutic approaches to treat periodontal diseases. Periodontol 2000 (2007) 1.44

Periodontal therapy reduces the severity of active rheumatoid arthritis in patients treated with or without tumor necrosis factor inhibitors. J Periodontol (2009) 1.44

The association between periodontal disease and joint destruction in rheumatoid arthritis extends the link between the HLA-DR shared epitope and severity of bone destruction. Ann Rheum Dis (2005) 1.38

Oral health in women during preconception and pregnancy: implications for birth outcomes and infant oral health. Matern Child Health J (2006) 1.37

Periodontitis in established rheumatoid arthritis patients: a cross-sectional clinical, microbiological and serological study. Arthritis Res Ther (2012) 1.23

Rothia aeria as a cause of sepsis in a native joint. J Clin Microbiol (2010) 1.10

A prospective study of periodontal disease and risk of rheumatoid arthritis. J Rheumatol (2010) 1.05

Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis? Arthritis Res Ther (2010) 1.03

Th1 immune response promotes severe bone resorption caused by Porphyromonas gingivalis. Am J Pathol (2007) 1.00

Rheumatoid arthritis and salivary biomarkers of periodontal disease. J Clin Periodontol (2010) 0.98

Immunoglobulin G and A antibody responses to Bacteroides forsythus and Prevotella intermedia in sera and synovial fluids of arthritis patients. Clin Diagn Lab Immunol (2003) 0.95

Identification of oral bacterial DNA in synovial fluid of patients with arthritis with native and failed prosthetic joints. J Clin Rheumatol (2012) 0.92

Oral bisphosphonate-related osteonecrosis of the jaws in rheumatoid arthritis patients: a critical discussion and two case reports. Head Face Med (2011) 0.89

Periodontal therapy in chronic periodontitis lowers gingival crevicular fluid interleukin-1beta and DAS28 in rheumatoid arthritis patients. Rheumatol Int (2013) 0.88

Effect of periodontal treatment on the clinical parameters of patients with rheumatoid arthritis: study protocol of the randomized, controlled ESPERA trial. Trials (2013) 0.87

Rheumatoid arthritis and the role of oral bacteria. J Oral Microbiol (2010) 0.87

Antibodies to Porphyromonas gingivalis Indicate Interaction Between Oral Infection, Smoking, and Risk Genes in Rheumatoid Arthritis Etiology. Arthritis Rheumatol (2016) 0.86

Effect of anti-rheumatic agents on periodontal parameters and biomarkers of inflammation: a systematic review and meta-analysis. J Periodontal Implant Sci (2012) 0.86

Influence of musculoskeletal conditions on oral health among older adults. Am J Public Health (2008) 0.84

Periodontitis treatment improves systemic lupus erythematosus response to immunosuppressive therapy. Clin Rheumatol (2014) 0.84

Is there a relationship between periodontitis and rheumatoid arthritis? J Indian Soc Periodontol (2012) 0.83

Host Responses in the Link Between Periodontitis and Rheumatoid Arthritis. Curr Oral Health Rep (2015) 0.83

Effect of rheumatoid arthritis on periodontitis: a historical cohort study. J Periodontal Implant Sci (2012) 0.82

Porphyromonas gingivalis Stimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-κB Ligand) through Activation of Toll-like Receptor 2 in Osteoblasts. J Biol Chem (2015) 0.82

Autoreactivity of serum immunoglobulin to periodontal tissue components: a pilot study. J Periodontol (2009) 0.81

Rheumatoid Arthritis Risk Associated with Periodontitis Exposure: A Nationwide, Population-Based Cohort Study. PLoS One (2015) 0.80

Association of levels of antibodies against citrullinated cyclic peptides and citrullinated α-enolase in chronic and aggressive periodontitis as a risk factor of Rheumatoid arthritis: a case control study. J Transl Med (2015) 0.79

Association between anti-Porphyromonas gingivalis or anti-α-enolase antibody and severity of periodontitis or rheumatoid arthritis (RA) disease activity in RA. BMC Musculoskelet Disord (2015) 0.79

Periodontal status of rheumatoid arthritis patients in khartoum state. BMC Res Notes (2011) 0.79

Significance of circulating and crevicular matrix metalloproteinase-9 in rheumatoid arthritis-chronic periodontitis association. J Immunol Res (2015) 0.77

GM-CSF and uPA are required for Porphyromonas gingivalis-induced alveolar bone loss in a mouse periodontitis model. Immunol Cell Biol (2015) 0.77

Rheumatoid Arthritis among Periodontitis Patients in Baddi Industrial Estate of Himachal Pradesh, India: A Cross Sectional Study. J Clin Diagn Res (2013) 0.76

Periodontitis increases rheumatic factor serum levels and citrullinated proteins in gingival tissues and alter cytokine balance in arthritic rats. PLoS One (2017) 0.75

Major involvement of bacterial components in rheumatoid arthritis and its accompanying oxidative stress, systemic inflammation and hypercoagulability. Exp Biol Med (Maywood) (2016) 0.75

General health screening as part of a periodontal examination. J Oral Microbiol (2010) 0.75

Tissue specific CD4+ T cell priming determines the requirement for interleukin-23 in experimental arthritis. Arthritis Res Ther (2014) 0.75

Effects by periodontitis on pristane-induced arthritis in rats. J Transl Med (2016) 0.75

Regenerative effect of hOPG gene-modified autologous PDLs in combination with cell transplantation on periodontal defection in beagle dogs. Cytotechnology (2016) 0.75

An Evaluation of Non-Surgical Periodontal Therapy in Patients with Rheumatoid Arthritis. Open Dent J (2015) 0.75

Influence of periodontitis on the experience of oral mucositis in cancer patients undergoing head and neck radiotherapy: a pilot study. Support Care Cancer (2014) 0.75

The efficacy of mesenchymal stem cells to regenerate and repair dental structures. Orthod Craniofac Res (2005) 1.97

Relationship between rheumatoid arthritis and periodontitis. J Periodontol (2001) 1.70

Periodontitis and rheumatoid arthritis: a review. J Periodontol (2005) 1.54

A clinical review of drug-induced gingival overgrowths. Aust Dent J (1999) 1.54

Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease. Periodontol 2000 (1997) 1.51

Inter-relationships between rheumatoid arthritis and periodontal disease. A review. J Clin Periodontol (2003) 1.48

Location of putative stem cells in human periodontal ligament. J Periodontal Res (2006) 1.42

Group C. Initiator paper. Periodontal regeneration--fact or fiction? J Int Acad Periodontol (2015) 1.39

Oral health report. Aust Dent J (2001) 1.38

Difficult decisions in the intensive care unit: an illustrative case. Anaesth Intensive Care (2007) 1.38

Stem cells in the periodontal ligament. Oral Dis (2006) 1.36

Ovine periodontal ligament stem cells: isolation, characterization, and differentiation potential. Calcif Tissue Int (2006) 1.26

Periodontal disease and rheumatoid arthritis: a systematic review. J Dent Res (2013) 1.18

Stem cells and periodontal regeneration. Aust Dent J (2008) 1.09

The effect of oxygen-derived free radicals on gingival proteoglycans and hyaluronic acid. J Periodontal Res (1984) 1.06

Genetic disorders of the gingivae and periodontium. Periodontol 2000 (1998) 1.03

Expression of peptidylarginine deiminase-2 and -4, citrullinated proteins and anti-citrullinated protein antibodies in human gingiva. J Periodontal Res (2012) 1.01

Induced pluripotent stem cell lines derived from human gingival fibroblasts and periodontal ligament fibroblasts. J Periodontal Res (2011) 1.01

Expression of transforming growth factor-beta 1 (TGF-beta1) in the developing periodontium of rats. J Dent Res (1998) 1.01

The epithelial cell rests of Malassez--a role in periodontal regeneration? J Periodontal Res (2006) 1.00

Is there a role for triclosan/copolymer toothpaste in the management of periodontal disease? Br Dent J (2009) 1.00

Genetic aspects of dental disorders. Aust Dent J (1998) 1.00

Prevalence of systemic diseases in Brisbane general and periodontal practice patients. Aust Dent J (2004) 0.99

Medication induced gingival overgrowth. Oral Dis (1998) 0.98

Treatment of xerostomia: a double-blind trial in 108 patients with Sjögren's syndrome. Oral Surg Oral Med Oral Pathol (1981) 0.96

Hereditary gingival fibromatosis associated with hearing loss and supernumerary teeth--a new syndrome. J Periodontol (1995) 0.95

Nitric oxide and tissue destruction. Oral Dis (2001) 0.94

Mesenchymal stem cells from iPS cells facilitate periodontal regeneration. J Dent Res (2013) 0.93

Effect of dietary omega-3 polyunsaturated fatty acids on experimental periodontitis in the mouse. J Periodontal Res (2009) 0.91

Nitric oxide synthase type-II is synthesized by human gingival tissue and cultured human gingival fibroblasts. J Periodontal Res (2000) 0.90

Expression of bone associated macromolecules by gingival and periodontal ligament fibroblasts. J Periodontal Res (2001) 0.89

Enamel matrix derivative induces matrix synthesis by cultured human periodontal fibroblast cells. J Periodontol (2001) 0.89

Effect of Emdogain on human periodontal fibroblasts in an in vitro wound-healing model. J Periodontal Res (2003) 0.89

Tissue engineering for bone regeneration using differentiated alveolar bone cells in collagen scaffolds. Tissue Eng (2003) 0.88

Growth factor modulation of mitogenic responses and proteoglycan synthesis by human periodontal fibroblasts. J Cell Physiol (1998) 0.88

Putative stem cells in regenerating human periodontium. J Periodontal Res (2008) 0.88

Emotional distress induced rhabdomyolysis in an individual with carnitine palmitoly-transferase deficiency. Clin Exp Rheumatol (2001) 0.88

Biochemistry of periodontal connective tissues and their regeneration: a current perspective. Connect Tissue Res (1996) 0.88

Detection of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 2(PAI-2) in gingival crevicular fluid from healthy, gingivitis and periodontitis patients. J Clin Periodontol (2000) 0.88

The effect of platelet-rich plasma on osteoblast and periodontal ligament cell migration, proliferation and differentiation. J Periodontal Res (2009) 0.87

Is there a role for the use of volumetric cone beam computed tomography in periodontics? Aust Dent J (2012) 0.87

Immunohistochemical localization of fibromodulin in the periodontium during cementogenesis and root formation in the rat molar. J Periodontal Res (2003) 0.86

Growth factors and cytokines modulate gene expression of cell-surface proteoglycans in human periodontal ligament cells. J Cell Physiol (2001) 0.86

Periodontal ligament-derived cells for periodontal regeneration in animal models: a systematic review. J Periodontal Res (2014) 0.86

Behavior of hyaluronic acid from gingival epithelium and connective tissue on the analytical ultracentrifuge. Connect Tissue Res (1984) 0.86

High antibody levels to P. gingivalis in cardiovascular disease. J Dent Res (2010) 0.85

Growth hormone and insulin-like growth factor I induce bone morphogenetic proteins 2 and 4: a mediator role in bone and tooth formation? Endocrinology (1998) 0.84

Stem cells, tissue engineering and periodontal regeneration. Aust Dent J (2013) 0.84

The effect of chronic inflammation on gingival connective tissue proteoglycans and hyaluronic acid. J Oral Pathol (1986) 0.84

Molecular weight estimation of sulfated glycosaminoglycans in human gingivae. Connect Tissue Res (1982) 0.84

Expression of bone matrix protein mRNAs by primary and cloned cultures of the regenerative phenotype of human periodontal fibroblasts. J Dent Res (2001) 0.84

Moving into a new era of periodontal genetic studies: relevance of large case-control samples using severe phenotypes for genome-wide association studies. J Periodontal Res (2014) 0.84

Periodontal-derived cells attach to cementum attachment protein via alpha 5 beta 1 integrin. J Periodontal Res (1999) 0.83

Prevalence, extent and severity of severe periodontal destruction in an urban Aboriginal and Torres Strait Islander population. Aust Dent J (2014) 0.83

Assessment of the regenerative potential of allogeneic periodontal ligament stem cells in a rodent periodontal defect model. J Periodontal Res (2013) 0.83

Inhibitors of histone deacetylases in class I and class II suppress human osteoclasts in vitro. J Cell Physiol (2011) 0.82

Inhibition of apoptosis in periodontitis. J Dent Res (2010) 0.82

Use of the Vector scaling unit in supportive periodontal therapy: a subjective patient evaluation. J Clin Periodontol (2005) 0.82

Growth hormone induces bone morphogenetic proteins and bone-related proteins in the developing rat periodontium. J Bone Miner Res (2001) 0.81

Isolation and characterization of fibroblasts derived from regenerating human periodontal defects. Arch Oral Biol (2001) 0.81

Proteoglycans synthesized by gingival fibroblasts derived from human donors of different ages. J Cell Physiol (1986) 0.81

Histone deacetylase inhibitors and periodontal bone loss. J Periodontal Res (2011) 0.81

The behaviour and proliferation of human dental pulp cell strains in vitro, and their response to the application of platelet-derived growth factor-BB and insulin-like growth factor-1. Int Endod J (1998) 0.81

Glycosaminoglycans in gingival crevicular fluid of patients with periodontal class II furcation involvement before and after guided tissue regeneration. A pilot study. J Periodontol (2000) 0.81

Proteoglycans of the periodontium: structure, role and function. J Periodontal Res (1987) 0.81

Thrombocytopenia corrected by warfarin in antiphospholipid syndrome. J Rheumatol (1996) 0.81

Establishing and managing a periodontal biobank for research: the sharing of experience. Oral Dis (2014) 0.81

Distribution and synthesis of elastin in porcine gingiva and alveolar mucosa. J Periodontal Res (2000) 0.81

Regulation of human gingival fibroblast growth and synthetic activity by cyclosporine-A in vitro. J Periodontal Res (1989) 0.81

Cell-surface proteoglycan expression by lymphocytes from peripheral blood and gingiva in health and periodontal disease. J Dent Res (2001) 0.81

An immunohistochemical study of matrix molecules associated with barrier membrane-mediated periodontal wound healing. J Periodontal Res (2000) 0.81

Tooth discoloration by blood: an in vitro histochemical study. Endod Dent Traumatol (1997) 0.80

Expression of extracellular matrix macromolecules around demineralized freeze-dried bone allografts. J Periodontol (1996) 0.80

Azithromycin suppresses P. gingivalis LPS-induced pro-inflammatory cytokine and chemokine production by human gingival fibroblasts in vitro. Clin Oral Investig (2014) 0.80

A microdetermination method for assaying glycosaminoglycans and proteoglycans. Anal Biochem (1985) 0.80

Proteoglycans from adult human gingival epithelium. Biochem J (1979) 0.80

Differential expression and distribution of syndecan-1 and -2 in periodontal wound healing of the rat. J Periodontal Res (2002) 0.80

Australian dentists' views on toothbrush wear and renewal. Aust Dent J (2000) 0.79

The expression of plasminogen activator system in a rat model of periodontal wound healing. J Periodontol (2001) 0.79

Hyaluronic acid synthesized by fibroblasts cultured from normal and chronically inflamed human gingivae. Coll Relat Res (1986) 0.79

Cytokine regulation of syndecan-1 and -2 gene expression in human periodontal fibroblasts and osteoblasts. J Periodontal Res (2002) 0.79

Proteomic identification of proteinase inhibitors in the porcine enamel matrix derivative, EMD(®). J Periodontal Res (2010) 0.79

Periodontal disease and dental caries among Indigenous Australians living in the Northern Territory, Australia. Aust Dent J (2014) 0.79

Glycosaminoglycans of human gingival epithelium and connective tissue. Connect Tissue Res (1981) 0.78

Isolation and characterization of proteoglycans synthesized by adult human gingival fibroblasts in vitro. Arch Biochem Biophys (1987) 0.78

Immunohistochemical localization and expression of fibromodulin in adult rat periodontium and inflamed human gingiva. Oral Dis (2004) 0.78

Proteoglycans in human gingiva: molecular size distribution in epithelium and in connective tissue. Arch Oral Biol (1982) 0.78

A scanning electron microscopic evaluation of root surfaces and the gutta-percha interface following root-end resection in vitro. Int Endod J (1999) 0.78

Continuing dental education in osseointegrated implants. A survey. Aust Dent J (2000) 0.78

The effect of interleukin-1 beta on hyaluronic acid synthesized by adult human gingival fibroblasts in vitro. J Periodontal Res (1988) 0.78

Expression of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor, fibroblast growth factor-inducible 14 protein (Fn14), in healthy tissues and in tissues affected by periodontitis. J Periodontal Res (2010) 0.78

Biomarkers of periodontal inflammation in the Australian adult population. Aust Dent J (2009) 0.78

A comparison of the effects of two kinds of glass-ionomer cement on human gingival fibroblast attachment, proliferation and morphology in vitro. J Int Acad Periodontol (2000) 0.78