Published in Int J Obes Relat Metab Disord on April 01, 2000
FAM-MDR: a flexible family-based multifactor dimensionality reduction technique to detect epistasis using related individuals. PLoS One (2010) 1.34
Associations between UCP1 -3826A/G, UCP2 -866G/A, Ala55Val and Ins/Del, and UCP3 -55C/T polymorphisms and susceptibility to type 2 diabetes mellitus: case-control study and meta-analysis. PLoS One (2013) 0.90
Trp64Arg polymorphism in beta3-adrenergic receptor gene is associated with decreased fat oxidation both in resting and aerobic exercise in the Japanese male. Exp Diabetes Res (2009) 0.80
Genetic Background, Adipocytokines, and Metabolic Disorders in Postmenopausal Overweight and Obese Women. Biochem Genet (2016) 0.75
Role of UCP1 Gene Variants in Interethnic Differences in the Development of Cardio-Metabolic Diseases. Front Genet (2017) 0.75
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med (2001) 56.11
Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med (1998) 25.66
Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. Lancet (2006) 15.32
Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet (2005) 13.18
A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet (1998) 8.02
Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. Eur Heart J (2005) 5.40
Medial artery calcification. A neglected harbinger of cardiovascular complications in non-insulin-dependent diabetes mellitus. Arterioscler Thromb Vasc Biol (1996) 3.77
Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study. Diabetologia (2001) 3.73
Diabetes and atherosclerosis: an epidemiologic view. Diabetes Metab Rev (1987) 2.88
Evidence-based nutritional approaches to the treatment and prevention of diabetes mellitus. Nutr Metab Cardiovasc Dis (2004) 2.77
NIDDM and its metabolic control predict coronary heart disease in elderly subjects. Diabetes (1994) 2.67
Link between plasma ceramides, inflammation and insulin resistance: association with serum IL-6 concentration in patients with coronary heart disease. Diabetologia (2009) 2.63
Prevention of Type II diabetes in subjects with impaired glucose tolerance: the Diabetes Prevention Study (DPS) in Finland. Study design and 1-year interim report on the feasibility of the lifestyle intervention programme. Diabetologia (1999) 2.51
Prevalence of age-associated memory impairment in a randomly selected population from eastern Finland. Neurology (1995) 2.44
Natural history of peripheral neuropathy in patients with non-insulin-dependent diabetes mellitus. N Engl J Med (1995) 2.29
Ten year mortality and causes of death in patients with rheumatoid arthritis. Br Med J (Clin Res Ed) (1985) 2.10
Comparison of insulin regimens in patients with non-insulin-dependent diabetes mellitus. N Engl J Med (1992) 2.09
Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide. Int J Obes (Lond) (2011) 2.08
Improved lifestyle and decreased diabetes risk over 13 years: long-term follow-up of the randomised Finnish Diabetes Prevention Study (DPS). Diabetologia (2012) 1.99
Hyperinsulinemia predicts coronary heart disease risk in healthy middle-aged men: the 22-year follow-up results of the Helsinki Policemen Study. Circulation (1998) 1.98
Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1. J Clin Invest (2000) 1.97
Predictors of stroke in middle-aged patients with non-insulin-dependent diabetes. Stroke (1996) 1.97
Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion. Diabetologia (2007) 1.97
Poor glycemic control predicts coronary heart disease events in patients with type 1 diabetes without nephropathy. Arterioscler Thromb Vasc Biol (1999) 1.95
Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland. Am J Hum Genet (2000) 1.93
Serum uric acid is a strong predictor of stroke in patients with non-insulin-dependent diabetes mellitus. Stroke (1998) 1.88
C-reactive protein and the development of the metabolic syndrome and diabetes in middle-aged men. Diabetologia (2004) 1.85
Association of Chlamydia pneumoniae and acute coronary heart disease events in non-insulin dependent diabetic and non-diabetic subjects in Finland. Eur Heart J (1996) 1.82
Randomised, placebo-controlled multicentre trial of clodronate in multiple myeloma. Finnish Leukaemia Group. Lancet (1992) 1.80
Risk factors predicting lower extremity amputations in patients with NIDDM. Diabetes Care (1996) 1.78
Impaired beta cell glucose sensitivity rather than inadequate compensation for insulin resistance is the dominant defect in glucose intolerance. Diabetologia (2010) 1.64
Dyslipidemia and hyperglycemia predict coronary heart disease events in middle-aged patients with NIDDM. Diabetes (1997) 1.64
Insulin resistance syndrome predicts coronary heart disease events in elderly nondiabetic men. Circulation (1999) 1.64
Synergistic effect of polymorphisms in uncoupling protein 1 and beta3-adrenergic receptor genes on basal metabolic rate in obese Finns. Diabetologia (1998) 1.63
Insulin resistance syndrome predicts the risk of coronary heart disease and stroke in healthy middle-aged men: the 22-year follow-up results of the Helsinki Policemen Study. Arterioscler Thromb Vasc Biol (2000) 1.62
European stroke prevention study: effectiveness of antiplatelet therapy in diabetic patients in secondary prevention of stroke. Stroke (1992) 1.59
Acarbose for the prevention of Type 2 diabetes, hypertension and cardiovascular disease in subjects with impaired glucose tolerance: facts and interpretations concerning the critical analysis of the STOP-NIDDM Trial data. Diabetologia (2004) 1.57
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. Diabetologia (2012) 1.55
Long-term effect of betaine on risk factors associated with the metabolic syndrome in healthy subjects. Eur J Clin Nutr (2010) 1.54
The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study. Diabetologia (2008) 1.53
Insulin action and age. European Group for the Study of Insulin Resistance (EGIR). Diabetes (1996) 1.52
Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23. Nat Genet (1998) 1.52
Does lactose intolerance predispose to low bone density? A population-based study of perimenopausal Finnish women. Bone (1996) 1.51
Increased serum levels of advanced glycation endproducts predict total, cardiovascular and coronary mortality in women with type 2 diabetes: a population-based 18 year follow-up study. Diabetologia (2007) 1.50
Low levels of sex hormone-binding globulin and testosterone are associated with smaller, denser low density lipoprotein in normoglycemic men. J Clin Endocrinol Metab (1996) 1.49
Association of angiotensin converting enzyme and plasminogen activator inhibitor-1 promoter gene polymorphisms with features of the insulin resistance syndrome in patients with premature coronary heart disease. Atherosclerosis (2001) 1.49
Leptin concentrations, sex hormones, and cortisol in nondiabetic men. J Clin Endocrinol Metab (1997) 1.49
Oxidised LDL and progression of atherosclerosis. Lancet (1992) 1.49
Effect of apolipoprotein E polymorphism on serum lipid response to the separate modification of dietary fat and dietary cholesterol. Am J Clin Nutr (1998) 1.47
Impairment of diastolic function in middle-aged type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetic patients free of cardiovascular disease. Diabetologia (1988) 1.46
Glucose regulation and chronic pain at multiple sites. Rheumatology (Oxford) (2008) 1.45
Association of metabolic syndrome with Alzheimer disease: a population-based study. Neurology (2006) 1.45
Adenovirus-mediated gene transfer to lower limb artery of patients with chronic critical leg ischemia. Hum Gene Ther (1998) 1.45
Apolipoprotein E phenotype and blood pressure. Lancet (1994) 1.45
Is there a sex difference in the association of plasma insulin level and insulin sensitivity with serum lipids and lipoproteins? Metabolism (1994) 1.42
Osteoporosis in adult patients with celiac disease. Bone (1999) 1.41
Cognitive load and detection thresholds in car following situations: safety implications for using mobile (cellular) telephones while driving. Accid Anal Prev (1999) 1.40
Cognitive function in an elderly population with persistent impaired glucose tolerance. Diabetes Care (1998) 1.39
Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects. Metabolism (2003) 1.38
Prevention strategies for type 2 diabetes should be based on evidence-based medical nutrition data. Diabetologia (2010) 1.38
Independent influence of age on basal insulin secretion in nondiabetic humans. European Group for the Study of Insulin Resistance. J Clin Endocrinol Metab (1999) 1.37
Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk. Carcinogenesis (2001) 1.37
Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial. Diabetologia (2004) 1.33
Verbal fluency activates the left medial temporal lobe: a functional magnetic resonance imaging study. Ann Neurol (2000) 1.32
High-fibre, low-fat diet predicts long-term weight loss and decreased type 2 diabetes risk: the Finnish Diabetes Prevention Study. Diabetologia (2006) 1.32
Evidence of a state of increased insulin resistance in preeclampsia. Metabolism (1999) 1.31
Anti-inflammatory effect of lifestyle changes in the Finnish Diabetes Prevention Study. Diabetologia (2009) 1.30
Proteinuria predicts stroke and other atherosclerotic vascular disease events in nondiabetic and non-insulin-dependent diabetic subjects. Stroke (1996) 1.29
Prevalence of retinopathy in people with diabetes, impaired glucose tolerance, and normal glucose tolerance. Diabetes Care (1998) 1.26
Weight reduction modulates expression of genes involved in extracellular matrix and cell death: the GENOBIN study. Int J Obes (Lond) (2007) 1.26
Cardiovascular disease risk factors as predictors of type 2 (non-insulin-dependent) diabetes mellitus in elderly subjects. Diabetologia (1993) 1.26
Shift in the incidence of rheumatoid arthritis toward elderly patients in Finland during 1975-1990. Clin Exp Rheumatol (1997) 1.24
Conjugated bile acids associate with altered rates of glucose and lipid oxidation after Roux-en-Y gastric bypass. Obes Surg (2012) 1.24
Polymorphic catechol-O-methyltransferase gene and breast cancer risk. Cancer Epidemiol Biomarkers Prev (2001) 1.23
A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference. Int J Obes Relat Metab Disord (2002) 1.21
Genomewide scan for familial combined hyperlipidemia genes in finnish families, suggesting multiple susceptibility loci influencing triglyceride, cholesterol, and apolipoprotein B levels. Am J Hum Genet (1999) 1.21
Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels. Nat Med (1998) 1.20
Prolongation of the Q-T interval caused by sotalol--possible association with ventricular tachyarrhythmias. Eur Heart J (1981) 1.20
Immunoreactive interleukin-6 and acute phase proteins as prognostic factors in multiple myeloma. Finnish Leukemia Group. Blood (1995) 1.20
Glycemic responses of oat bran products in type 2 diabetic patients. Nutr Metab Cardiovasc Dis (2005) 1.20
Age and gender dependency of baroreflex sensitivity in healthy subjects. J Appl Physiol (1985) (1998) 1.19
Mechanism of insulin resistance in insulin-dependent diabetes mellitus: a major role for reduced skeletal muscle blood flow. J Clin Endocrinol Metab (1991) 1.19
Insulin resistance, body fat distribution, and sex hormones in men. Diabetes (1994) 1.19
Subjective memory complaints and personality traits in normal elderly subjects. J Am Geriatr Soc (1994) 1.19