Published in Circ Res on May 12, 2000
Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Nat Rev Mol Cell Biol (2009) 5.55
Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis. J Cell Biol (2005) 2.75
Signaling and functions of angiopoietin-1 in vascular protection. Circ Res (2006) 2.34
Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis. Adv Drug Deliv Rev (2010) 2.21
Strategies to promote donor cell survival: combining preconditioning approach with stem cell transplantation. J Mol Cell Cardiol (2008) 2.16
COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity. Proc Natl Acad Sci U S A (2004) 1.85
VE-statin, an endothelial repressor of smooth muscle cell migration. EMBO J (2003) 1.84
Angiogenetic signaling through hypoxia: HMGB1: an angiogenetic switch molecule. Am J Pathol (2005) 1.75
Mechanism and its regulation of tumor-induced angiogenesis. World J Gastroenterol (2003) 1.55
Angiogenic actions of angiopoietin-1 require endothelium-derived nitric oxide. Am J Pathol (2003) 1.48
Bench-to-bedside review: Angiopoietin signalling in critical illness - a future target? Crit Care (2009) 1.45
Designed angiopoietin-1 variant, COMP-Ang1, protects against radiation-induced endothelial cell apoptosis. Proc Natl Acad Sci U S A (2004) 1.34
Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues. Arthritis Res Ther (2007) 1.25
Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium. Mol Cell Biol (2001) 1.15
Regulation of angiogenesis by vascular endothelial growth factor and angiopoietin-1 in the rat aorta model: distinct temporal patterns of intracellular signaling correlate with induction of angiogenic sprouting. Am J Pathol (2002) 1.09
The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis. Mol Cell Biol (2002) 1.06
A cyclosporine-sensitive psoriasis-like disease produced in Tie2 transgenic mice. Am J Pathol (2005) 1.04
FADD negatively regulates lipopolysaccharide signaling by impairing interleukin-1 receptor-associated kinase 1-MyD88 interaction. Mol Cell Biol (2007) 1.04
Intra and extravascular transmembrane signalling of angiopoietin-1-Tie2 receptor in health and disease. J Cell Mol Med (2008) 0.97
Preeclampsia and small-for-gestational age are associated with decreased concentrations of a factor involved in angiogenesis: soluble Tie-2. J Matern Fetal Neonatal Med (2008) 0.92
Emerging roles of focal adhesion kinase in cancer. Biomed Res Int (2015) 0.90
Angiopoietin-1 causes reversible degradation of the portal microcirculation in mice: implications for treatment of liver disease. Am J Pathol (2004) 0.90
Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke. Neurobiol Dis (2014) 0.90
Activated protein C enhances human keratinocyte barrier integrity via sequential activation of epidermal growth factor receptor and Tie2. J Biol Chem (2010) 0.86
Ligustrazine monomer against cerebral ischemia/reperfusion injury. Neural Regen Res (2015) 0.84
Vascular disruption and the role of angiogenic proteins after spinal cord injury. Transl Stroke Res (2011) 0.84
Optimizing stem cell function for the treatment of ischemic heart disease. J Surg Res (2010) 0.83
Molecular and cellular basis of viable dysfunctional myocardium. Circ Heart Fail (2014) 0.83
Antisense angiopoietin-1 inhibits tumorigenesis and angiogenesis of gastric cancer. World J Gastroenterol (2006) 0.82
Plasma vascular endothelial growth factor and serum soluble angiopoietin receptor sTIE-2 in patients with dural arteriovenous fistulas: a pilot study. Neuroradiology (2005) 0.81
Human iPSC-derived endothelial cell sprouting assay in synthetic hydrogel arrays. Acta Biomater (2016) 0.79
Down-regulation of angiopoietin-1 expression in menorrhagia. Am J Pathol (2002) 0.79
Optimizing stem cells for cardiac repair: Current status and new frontiers in regenerative cardiology. World J Stem Cells (2017) 0.78
The Angiopoietin-1 Variant COMP-Ang1 Enhances BMP2-Induced Bone Regeneration with Recruiting Pericytes in Critical Sized Calvarial Defects. PLoS One (2015) 0.77
The role of angiopoietin-1 in kidney disease. Electrolyte Blood Press (2008) 0.77
Measurement of angiogenic phenotype by use of two-dimensional mesenteric angiogenesis assay. Methods Mol Biol (2009) 0.77
Designed angiopoietin-1 variant, COMP-angiopoietin-1, rescues erectile function through healthy cavernous angiogenesis in a hypercholesterolemic mouse. Sci Rep (2015) 0.76
Coculturing Human Islets with Proangiogenic Support Cells to Improve Islet Revascularization at the Subcutaneous Transplantation Site. Tissue Eng Part A (2016) 0.75
Effects of CASP5 gene overexpression on angiogenesis of HMEC-1 cells. Int J Clin Exp Pathol (2015) 0.75
Behaviour of endothelial cells in a tridimensional in vitro environment. Biomed Res Int (2015) 0.75
Pharmacological Tie2 activation in kidney transplantation. World J Transplant (2016) 0.75
Regulation of Angiogenic Functions by Angiopoietins through Calcium-Dependent Signaling Pathways. Biomed Res Int (2015) 0.75
A novel cyclin encoded by a bcl1-linked candidate oncogene. Nature (1991) 7.98
Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3'-Kinase/Akt signal transduction pathway. Circ Res (2000) 4.97
Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts. J Clin Invest (1996) 3.87
Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells. J Biol Chem (2000) 3.45
Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium. Science (1994) 3.24
Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Oncogene (2000) 2.32
Adding posterior lumbar interbody fusion to pedicle screw fixation and posterolateral fusion after decompression in spondylolytic spondylolisthesis. Spine (Phila Pa 1976) (1997) 2.26
Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis. Biochem J (2000) 2.09
Cyclin D1 overexpression promotes cardiomyocyte DNA synthesis and multinucleation in transgenic mice. J Clin Invest (1997) 2.00
Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression. Circ Res (2001) 1.99
Clinical outcomes and risk factors of post-polypectomy coagulation syndrome: a multicenter, retrospective, case-control study. Endoscopy (2013) 1.91
Coadministration of angiopoietin-1 and vascular endothelial growth factor enhances collateral vascularization. Arterioscler Thromb Vasc Biol (2000) 1.71
Molecular cloning, expression, and characterization of angiopoietin-related protein. angiopoietin-related protein induces endothelial cell sprouting. J Biol Chem (1999) 1.69
Molecular cloning and chromosomal mapping of DNA rearranged with the parathyroid hormone gene in a parathyroid adenoma. J Clin Invest (1989) 1.64
Angiopoietin-1 is an apoptosis survival factor for endothelial cells. FEBS Lett (1999) 1.62
Prognostic implications of type and density of tumour-infiltrating lymphocytes in gastric cancer. Br J Cancer (2008) 1.62
Monoclonality and abnormal parathyroid hormone genes in parathyroid adenomas. N Engl J Med (1988) 1.61
Combined modality therapy of A431 human epidermoid cancer using anti-EGFr antibody C225 and radiation. Cancer Biother Radiopharm (1999) 1.49
Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors. Oncogene (1991) 1.44
Molecular mechanism of staurosporine-induced apoptosis in osteoblasts. Pharmacol Res (2000) 1.32
Hypogonadotropic hypogonadism and cleft lip and palate caused by a balanced translocation producing haploinsufficiency for FGFR1. J Med Genet (2005) 1.32
Peripheral ossifying fibroma in the oral cavity: CT and MR findings. Dentomaxillofac Radiol (2007) 1.32
Negative regulation of Sp1 trans-activation is correlated with the binding of cellular proteins to the amino terminus of the Sp1 trans-activation domain. J Biol Chem (1994) 1.29
The mouse Pdgfc gene: dynamic expression in embryonic tissues during organogenesis. Mech Dev (2000) 1.29
Hybrid natural orifice transluminal endoscopic surgery: endoscopic full-thickness resection of early gastric cancer and laparoscopic regional lymph node dissection--14 human cases. Endoscopy (2010) 1.27
A role for phospholipase C-gamma-mediated signaling in tumor cell invasion. Clin Cancer Res (1999) 1.25
Tumor necrosis factor-alpha upregulates angiopoietin-2 in human umbilical vein endothelial cells. Biochem Biophys Res Commun (2000) 1.21
Differential and dramatic changes of cyclin-dependent kinase activities in cardiomyocytes during the neonatal period. J Mol Cell Cardiol (1997) 1.16
A novel fibroblast growth factor receptor-5 preferentially expressed in the pancreas(1). Biochim Biophys Acta (2001) 1.16
Angiopoietin-1 inhibits irradiation- and mannitol-induced apoptosis in endothelial cells. Circulation (2000) 1.14
Propofol attenuates ischemia-reperfusion injury in the isolated rat heart. Anesth Analg (1997) 1.08
Gene therapy for gastric ulcers with single local injection of naked DNA encoding VEGF and angiopoietin-1. Gastroenterology (2001) 1.04
Tumor suppressor gene expression during normal and pathologic myocardial growth. J Biol Chem (1994) 1.04
Endoscopic submucosal dissection with sentinel node navigation surgery for early gastric cancer. Endoscopy (2012) 1.04
A multicenter, phase II trial of everolimus in locally advanced or metastatic thyroid cancer of all histologic subtypes. Ann Oncol (2013) 1.03
Inhibition of cytosolic phospholipase A2 by annexin I. Specific interaction model and mapping of the interaction site. J Biol Chem (2001) 0.99
PLC gamma contributes to metastasis of in situ-occurring mammary and prostate tumors. Oncogene (2006) 0.99
Role of aiNa in positive force-frequency staircase in guinea pig papillary muscle. Am J Physiol (1988) 0.99
Functional hemizygosity of PAFAH1B3 due to a PAFAH1B3-CLK2 fusion gene in a female with mental retardation, ataxia and atrophy of the brain. Hum Mol Genet (2001) 0.99
High-resolution impedance manometry facilitates assessment of pharyngeal residue and oropharyngeal dysphagic mechanisms. Dis Esophagus (2013) 0.98
Systematic Numbering of Vegetative Compatibility Groups in the Plant Pathogenic Fungus Fusarium oxysporum. Phytopathology (1998) 0.98
A case of torsade de pointes associated with hypopituitarism due to hemorrhagic fever with renal syndrome. J Korean Med Sci (2001) 0.98
Phorbol esters potentiate tyrosine phosphorylation of epidermal growth factor receptors in A431 membranes by a calcium-independent mechanism. Proc Natl Acad Sci U S A (1984) 0.98
Presence and biological activity of C-type natriuretic peptide-dependent guanylate cyclase-coupled receptor in the penile corpus cavernosum. J Urol (1998) 0.97
The angiopoietin-tie2 system in coronary artery endothelium prevents oxidized low-density lipoprotein-induced apoptosis. Cardiovasc Res (2001) 0.96
Comparing the accuracy of ThinPrep Pap tests and conventional Papanicolaou smears on the basis of the histologic diagnosis: a clinical study of women with cervical abnormalities. Acta Cytol (2001) 0.95
Detection of a novel cell cycle-regulated kinase activity that associates with the amino terminus of the retinoblastoma protein in G2/M phases. J Biol Chem (1995) 0.95
Factors affecting the long-term patency of crossover femorofemoral bypass graft. Eur J Vasc Endovasc Surg (2005) 0.95
Characterization and expression of a novel alternatively spliced human angiopoietin-2. J Biol Chem (2000) 0.93
A phase II trial of S-1 and cisplatin in patients with metastatic or relapsed biliary tract cancer. Ann Oncol (2007) 0.92
Dexamethasone suppresses tumor necrosis factor-alpha-induced apoptosis in osteoblasts: possible role for ceramide. Endocrinology (2000) 0.92
Characterization of endonucleolytic activity of HIV-1 integrase using a fluorogenic substrate. Anal Biochem (1995) 0.92
A murine model of toluene diisocyanate-induced asthma can be treated with matrix metalloproteinase inhibitor. J Allergy Clin Immunol (2001) 0.91
Efficacy of terbinafine compared to lanoconazole and luliconazole in the topical treatment of dermatophytosis in a guinea pig model. Med Mycol (2010) 0.91
Coriandrum sativum L. protects human keratinocytes from oxidative stress by regulating oxidative defense systems. Skin Pharmacol Physiol (2012) 0.91
Surgical treatment of post-traumatic stiffness of the elbow. J Bone Joint Surg Br (2004) 0.90
Cytoplasmic localization of cyclin D3 in seminiferous tubules during testicular development. Exp Cell Res (1997) 0.90
Localization of the cyclic ADP-ribose-dependent calcium signaling pathway in hepatocyte nucleus. J Biol Chem (2000) 0.90
Prevention of bone loss in ovariectomized rats: the effect of Salvia miltiorrhiza extracts. Immunopharmacol Immunotoxicol (2004) 0.90
Persistent and heterogenous expression of the cyclin-dependent kinase inhibitor, p27KIP1, in rat hearts during development. J Mol Cell Cardiol (1998) 0.89
Molecular cloning and characterization of mouse cardiac junctate isoforms. Biochem Biophys Res Commun (2001) 0.89
Carbon monoxide and nitric oxide protect against tumor necrosis factor-alpha-induced apoptosis in osteoblasts: HO-1 is necessary to mediate the protection. Clin Chim Acta (2005) 0.89
Follicular dendritic cell sarcoma presenting as a submucosal tumor of the stomach. Arch Pathol Lab Med (2000) 0.89
Placenta hominis protects osteoporosis in ovariectomized rats. Immunopharmacol Immunotoxicol (2006) 0.88
The amino terminus of the retinoblastoma (Rb) protein associates with a cyclin-dependent kinase-like kinase via Rb amino acids required for growth suppression. Cell Growth Differ (1996) 0.87
Renal tubule regeneration after ischemic injury is coupled to the up-regulation and activation of cyclins and cyclin dependent kinases. Kidney Int (1997) 0.87
The seventh Korea-Japan joint symposium on cancer and ageing research: molecular targets in cancer and ageing research. J Cancer Res Clin Oncol (2006) 0.87
Diagnostic application of serum proteomic patterns in gastric cancer patients by ProteinChip surface-enhanced laser desorption/ionization time-of-flight mass spectrometry. Int J Biol Markers (2007) 0.86
Mercury inhalation poisoning and acute lung injury. Korean J Intern Med (1998) 0.86
Temporal expressions of cyclins and cyclin dependent kinases during renal development and compensatory growth. Kidney Int (1997) 0.86
Knowledge and attitudes of Korean parents towards their son's circumcision: a nationwide questionnaire study. BJU Int (2002) 0.86
Manganese: a transition metal protects nigrostriatal neurons from oxidative stress in the iron-induced animal model of parkinsonism. Neuroscience (1998) 0.86
Hypoxia induces apoptosis by caspase activation accompanying cytochrome C release from mitochondria in MC3T3E1 osteoblasts. p38 MAPK is related in hypoxia-induced apoptosis. Immunopharmacol Immunotoxicol (2001) 0.85
Blockade of myocardial ATP-sensitive potassium channels by ketamine. Anesthesiology (1997) 0.85
Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin-3. FEBS Lett (1999) 0.85
Intraoral mandibular distraction osteogenesis in facial asymmetry patients with unilateral temporomandibular joint bony ankylosis. Int J Oral Maxillofac Surg (2002) 0.85
A case of flutamide-induced acute cholestatic hepatitis--a case report. Yonsei Med J (1996) 0.84
The putative oncogene PRAD1 encodes a novel cyclin. Cold Spring Harb Symp Quant Biol (1991) 0.84
Substrate-length-dependent activities of human immunodeficiency virus type 1 integrase in vitro: differential DNA binding affinities associated with different lengths of substrates. Biochemistry (1995) 0.84
Correlation between the in vitro ATP-based chemosensitivity assay and HER2/neu expression in women with breast cancer. J Int Med Res (2007) 0.84
Inhibition of nitric oxide synthesis by butanol fraction of the methanol extract of Ulmus davidiana in murine macrophages. J Ethnopharmacol (1998) 0.84
Clearance receptor and neutral endopeptidase-mediated metabolism of atrial natriuretic factor. Am J Physiol (1992) 0.83
Clonal loss of one chromosome 11 in a parathyroid adenoma. J Clin Endocrinol Metab (1989) 0.83
Clinical analysis of extranodal non-Hodgkin's lymphoma in the sinonasal tract. Eur Arch Otorhinolaryngol (2003) 0.83