Published in Mol Endocrinol on May 01, 2000
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta. Nat Struct Mol Biol (2007) 4.10
The NR4A subgroup: immediate early response genes with pleiotropic physiological roles. Nucl Recept Signal (2006) 2.35
Determinants of CoRNR-dependent repression complex assembly on nuclear hormone receptors. Mol Cell Biol (2001) 1.50
The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker. J Mol Endocrinol (2004) 1.50
The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta. PLoS Biol (2009) 1.31
X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation. EMBO J (2001) 1.27
Nuclear receptors homo sapiens Rev-erbbeta and Drosophila melanogaster E75 are thiolate-ligated heme proteins which undergo redox-mediated ligand switching and bind CO and NO. Biochemistry (2009) 1.13
The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation? Nucl Recept Signal (2006) 1.08
A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor. Nat Struct Mol Biol (2010) 0.99
Adopting new orphans into the family of metabolic regulators. Mol Endocrinol (2008) 0.95
The orphan nuclear receptors at their 25-year reunion. J Mol Endocrinol (2013) 0.80
Structure of REV-ERBβ ligand-binding domain bound to a porphyrin antagonist. J Biol Chem (2014) 0.78
The loss of transcriptional inhibition by the photoreceptor-cell specific nuclear receptor (NR2E3) is not a necessary cause of enhanced S-cone syndrome. Mol Vis (2007) 0.78
Altered Sleep Homeostasis in Rev-erbα Knockout Mice. Sleep (2016) 0.77
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes Dev (1998) 4.78
Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. Genes Dev (2000) 4.00
SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev Biol (1997) 3.84
Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature (2000) 3.41
Chemistry for peptide and protein PEGylation. Adv Drug Deliv Rev (2002) 3.35
Preseason strength and flexibility imbalances associated with athletic injuries in female collegiate athletes. Am J Sports Med (1991) 2.94
Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis. Mol Cell (2001) 2.69
Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. Genes Dev (2001) 2.68
Carbon dioxide starvation, the development of C4 ecosystems, and mammalian evolution. Philos Trans R Soc Lond B Biol Sci (1998) 2.66
Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function. AIDS (2001) 2.47
Guidance of locomotion on foot uses perceived target location rather than optic flow. Curr Biol (1998) 2.14
Technical efficiencies of Turkish hospitals: DEA approach. J Med Syst (1997) 2.14
Unique forms of human and mouse nuclear receptor corepressor SMRT. Proc Natl Acad Sci U S A (1999) 2.10
A Wnt signaling pathway controls hox gene expression and neuroblast migration in C. elegans. Development (1999) 2.03
Adenovirus E1A products suppress myogenic differentiation and inhibit transcription from muscle-specific promoters. Nature (1988) 1.95
Postendocytotic sorting of the ligand for the polymeric immunoglobulin receptor in Madin-Darby canine kidney cells. J Cell Biol (1989) 1.94
Septic arthritis of the shoulder in adults. J Bone Joint Surg Am (1989) 1.88
Expression and analysis of the polymeric immunoglobulin receptor in Madin-Darby canine kidney cells using retroviral vectors. Methods Cell Biol (1989) 1.75
Transcriptional repression by the insulator protein CTCF involves histone deacetylases. Nucleic Acids Res (2000) 1.74
Control of protein-ligand recognition using a stimuli-responsive polymer. Nature (1995) 1.73
Direct evidence for thymic function in adult humans. J Exp Med (1999) 1.70
A dynamic role for HDAC7 in MEF2-mediated muscle differentiation. J Biol Chem (2001) 1.68
The effects of lebrikizumab in patients with mild asthma following whole lung allergen challenge. Clin Exp Allergy (2014) 1.65
The steroid receptor coactivator, GRIP-1, is necessary for MEF-2C-dependent gene expression and skeletal muscle differentiation. Genes Dev (2000) 1.59
Intrinsic risk factors for exercise-related injuries among male and female army trainees. Am J Sports Med (1993) 1.53
Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits. Structure (1996) 1.46
Placental transfer of tubocurarine. Case report. Br J Anaesth (1968) 1.44
Contrast nephrotoxicity and iso-osmolar contrast agents: implications of NEPHRIC. Clin Radiol (2003) 1.39
The corepressor N-CoR and its variants RIP13a and RIP13Delta1 directly interact with the basal transcription factors TFIIB, TAFII32 and TAFII70. Nucleic Acids Res (1998) 1.39
Nucleotide sequence and expression of the human skeletal alpha-actin gene: evolution of functional regulatory domains. Genomics (1988) 1.37
Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function. Mol Endocrinol (2001) 1.35
Acute infective exacerbations of chronic bronchitis. QJM (1995) 1.33
Dietary and environmental reconstruction with stable isotope analyses of herbivore tooth enamel from the Miocene locality of Fort Ternan, Kenya. J Hum Evol (1997) 1.32
Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript. Hum Genet (2011) 1.32
Angiotensin II regulates nephrogenesis and renal vascular development. Am J Physiol (1995) 1.29
An anchor-minus form of the polymeric immunoglobulin receptor is secreted predominantly apically in Madin-Darby canine kidney cells. J Cell Biol (1987) 1.29
Two receptor interaction domains in the corepressor, N-CoR/RIP13, are required for an efficient interaction with Rev-erbA alpha and RVR: physical association is dependent on the E region of the orphan receptors. Nucleic Acids Res (1996) 1.28
Holmium:YAG percutaneous nephrolithotomy: the laser incident angle matters. J Urol (1998) 1.28
Interleukin-2-induced production of interferon-gamma by resting human T cells and large granular lymphocytes: requirement for accessory cell factors, including interleukin-1. Cell Immunol (1988) 1.27
The human glutathione S-transferase supergene family, its polymorphism, and its effects on susceptibility to lung cancer. Environ Health Perspect (1992) 1.26
Corepressors and nuclear hormone receptor function. Curr Top Microbiol Immunol (2001) 1.24
Cell salvage auto transfusion in total knee replacement surgery. Transfus Med (1997) 1.21
Prevention of lower extremity stress fractures: a controlled trial of a shock absorbent insole. Am J Public Health (1988) 1.19
Design variability in web geometry of an orb-weaving spider. Physiol Behav (1997) 1.17
Collocation of androgen receptor gene mutations in prostate cancer. Clin Cancer Res (2001) 1.17
Active repression of RAR signaling is required for head formation. Genes Dev (2001) 1.16
The transcriptional factor LBP-1c/CP2/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease. Hum Mol Genet (2000) 1.16
Contribution of APOE promoter polymorphisms to Alzheimer's disease risk. Neurology (2002) 1.14
Subcellular localization of the steroid receptor coactivators (SRCs) and MEF2 in muscle and rhabdomyosarcoma cells. Mol Endocrinol (2001) 1.14
An outbreak of asthma in a modern detergent factory. Lancet (2000) 1.14
Constitutive expression of the orphan receptor, Rev-erbA alpha, inhibits muscle differentiation and abrogates the expression of the myoD gene family. Mol Endocrinol (1995) 1.13
Strength, flexibility and athletic injuries. Sports Med (1992) 1.12
Exercise-induced stress fractures and stress reactions of bone: epidemiology, etiology, and classification. Exerc Sport Sci Rev (1989) 1.12
Improvements in protein PEGylation: pegylated interferons for treatment of hepatitis C. J Control Release (2001) 1.11
Holmium:yttrium-aluminum-garnet laser cystolithotripsy of large bladder calculi. Urology (1997) 1.10
Virus-directed, enzyme prodrug therapy with nitroimidazole reductase: a phase I and pharmacokinetic study of its prodrug, CB1954. Clin Cancer Res (2001) 1.09
Protein-rejecting ability of surface-bound dextran in end-on and side-on configurations: comparison to PEG. J Biomed Mater Res (1995) 1.09
Lateral diffusion of molecules partitioned into C-18 ligands on silica surfaces. Anal Chem (1995) 1.08
A branched monomethoxypoly(ethylene glycol) for protein modification. Bioconjug Chem (1995) 1.08
The nuclear receptor corepressor N-CoR regulates differentiation: N-CoR directly interacts with MyoD. Mol Endocrinol (1999) 1.08
Identification of a thyroid hormone response element in the mouse myogenin gene: characterization of the thyroid hormone and retinoid X receptor heterodimeric binding site. Cell Growth Differ (1993) 1.07
Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer. J Biol Chem (2000) 1.07
Evidence for a microviscosity increase in the Escherichia coli cell envelope caused by colicin E1. Biochemistry (1974) 1.06
Cautionary note on the use of dUMP-containing PCR primers with Pfu and VentR DNA polymerases. Biotechniques (1996) 1.06
Preparation of characterization of poly(ethylene glycol) vinyl sulfone. Bioconjug Chem (1996) 1.06
Hox gene expression in a single Caenorhabditis elegans cell is regulated by a caudal homolog and intercellular signals that inhibit wnt signaling. Development (1999) 1.06
Partitioning effects during terminal carbon and electron flow in sediments of a low-salinity meltwater pond near Bratina Island, McMurdo Ice Shelf, Antarctica. Appl Environ Microbiol (1999) 1.05
Multiwavelength fluorescence detection for DNA sequencing using capillary electrophoresis. Nucleic Acids Res (1991) 1.04
Regulation of vertebrate muscle differentiation by thyroid hormone: the role of the myoD gene family. Bioessays (1995) 1.04
Comparison of models describing the thermal lens effect. Appl Opt (1984) 1.04
Transcriptional repression by the orphan steroid receptor RVR/Rev-erb beta is dependent on the signature motif and helix 5 in the E region: functional evidence for a biological role of RVR in myogenesis. Nucleic Acids Res (1996) 1.04
Exogenous expression of a dominant negative RORalpha1 vector in muscle cells impairs differentiation: RORalpha1 directly interacts with p300 and myoD. Nucleic Acids Res (1999) 1.02
Early responses of trans-activating factors to growth hormone in preadipocytes: differential regulation of CCAAT enhancer-binding protein-beta (C/EBP beta) and C/EBP delta. Mol Endocrinol (1995) 1.02
Development of pegylated interferons for the treatment of chronic hepatitis C. BioDrugs (2001) 1.02
Ureteroscopic management of ureteral calculi: electrohydraulic versus holmium:YAG lithotripsy. J Urol (1997) 1.02
Activation of myoD gene transcription by 3,5,3'-triiodo-L-thyronine: a direct role for the thyroid hormone and retinoid X receptors. Nucleic Acids Res (1994) 1.01
Reduction of fibrinogen adsorption on PEG-coated polystyrene surfaces. J Biomed Mater Res (1992) 1.01
Interaction of HLA phenotype and exposure intensity in sensitization to complex platinum salts. Am J Respir Crit Care Med (1999) 1.00
Trans-activation and DNA-binding properties of the transcription factor, Sox-18. Nucleic Acids Res (1995) 1.00
The application of urine tests to monitor the regularity of dapsone self-administration. Lepr Rev (1974) 1.00
Early allergen exposure, skin prick responses, and atopic wheeze at age 5 in English children: a cohort study. Thorax (2004) 0.99
Actinomycin inhibition of MS2 replication. J Mol Biol (1966) 0.99
Are the estrogen receptors involved in Alzheimer's disease? Neurosci Lett (2001) 0.98
Sixty years on: the price of assembling military gas masks in 1940. Occup Environ Med (2006) 0.98
A study of hypoallergenic diets and oral sodium cromoglycate in the management of atopic eczema. Br J Dermatol (1984) 0.97
Evidence that amikacin ototoxicity is related to total perilymph area under the concentration-time curve regardless of concentration. Antimicrob Agents Chemother (1991) 0.97
Identification and characterization of a novel corepressor interaction region in RVR and Rev-erbA alpha. Mol Endocrinol (1998) 0.97
Changes in levels of actin and tubulin mRNAs upon the lectin activation of lymphocytes. Mol Cell Biol (1984) 0.96
Prenatal expression of the growth hormone (GH) receptor/binding protein in the rat: a role for GH in embryonic and fetal development? Development (1992) 0.96
The dance of the Hox genes: patterning the anteroposterior body axis of Caenorhabditis elegans. Cold Spring Harb Symp Quant Biol (1997) 0.95
Identification of a regulatory function for an orphan receptor in muscle: COUP-TF II affects the expression of the myoD gene family during myogenesis. Nucleic Acids Res (1995) 0.95
Risk factors for sensitisation and respiratory symptoms among workers exposed to acid anhydrides: a cohort study. Occup Environ Med (1998) 0.95
Can early infection explain the sibling effect in adult atopy? Eur Respir J (2003) 0.95