Hypernatremia.

The epidemiology of intensive care unit-acquired hyponatraemia and hypernatraemia in medical-surgical intensive care units. Crit Care (2008) 2.17

Thrombin. Mol Aspects Med (2008) 1.80

Medical costs of abnormal serum sodium levels. J Am Soc Nephrol (2008) 1.56

Are patients admitted to hospitals from care homes dehydrated? A retrospective analysis of hypernatraemia and in-hospital mortality. J R Soc Med (2015) 1.44

Simplified treatment strategies to fluid therapy in diarrhea. Pediatr Nephrol (2003) 1.42

Prognostic consequences of borderline dysnatremia: pay attention to minimal serum sodium change. Crit Care (2013) 1.20

Disturbances of sodium in critically ill adult neurologic patients: a clinical review. J Neurosurg Anesthesiol (2006) 1.18

Tonicity-independent regulation of the osmosensitive transcription factor TonEBP (NFAT5). Am J Physiol Cell Physiol (2011) 1.15

Management of sodium disorders during continuous haemofiltration. Crit Care (2010) 1.00

Electrolytes in the aging. Adv Chronic Kidney Dis (2010) 0.98

Clinical review: Critical care management of spontaneous intracerebral hemorrhage. Crit Care (2008) 0.96

Continuous controlled-infusion of hypertonic saline solution in traumatic brain-injured patients: a 9-year retrospective study. Crit Care (2011) 0.95

A review of drug-induced hypernatraemia. NDT Plus (2009) 0.93

'Wine Glass' sign in recurrent postpartum hypernatremic osmotic cerebral demyelination. Ann Indian Acad Neurol (2013) 0.90

Mixed acid-base disorders, hydroelectrolyte imbalance and lactate production in hypercapnic respiratory failure: the role of noninvasive ventilation. PLoS One (2012) 0.89

A Case of Osmotic Demyelination Presenting with Severe Hypernatremia. Electrolyte Blood Press (2015) 0.89

Predictors and outcome of hypoxemia in severely malnourished children under five with pneumonia: a case control design. PLoS One (2013) 0.89

Microworm optode sensors limit particle diffusion to enable in vivo measurements. Proc Natl Acad Sci U S A (2011) 0.88

Outcome analysis and outcome predictors of traumatic head injury in childhood: Analysis of 454 observations. J Emerg Trauma Shock (2011) 0.87

Hypernatremia in the elderly. J Natl Med Assoc (2002) 0.87

Long-term changes in dysnatremia incidence in the ICU: a shift from hyponatremia to hypernatremia. Ann Intensive Care (2016) 0.85

Secretion of von Willebrand factor by endothelial cells links sodium to hypercoagulability and thrombosis. Proc Natl Acad Sci U S A (2014) 0.85

Central pontine myelinolysis in a patient with persistent mild hypernatremia following cadaver donor liver transplantation. Korean J Anesthesiol (2013) 0.83

Use of only oral rehydration salt solution for successful management of a young infant with serum sodium of 201 mmol/L in an urban diarrhoeal diseases hospital, Bangladesh. J Health Popul Nutr (2012) 0.83

Best practice in primary care pathology: review 8. J Clin Pathol (2006) 0.83

Pediatric fluid and electrolyte therapy. J Pediatr Pharmacol Ther (2009) 0.83

Prognostic value of ICU-acquired hypernatremia in patients with neurological dysfunction. Medicine (Baltimore) (2016) 0.82

Body fluids and salt metabolism - part II. Ital J Pediatr (2010) 0.82

The frequency, cost, and clinical outcomes of hypernatremia in patients hospitalized to a comprehensive cancer center. Support Care Cancer (2013) 0.82

Undercorrection of hypernatremia is frequent and associated with mortality. BMC Nephrol (2014) 0.81

Volume depletion versus dehydration: how understanding the difference can guide therapy. Am J Kidney Dis (2011) 0.81

Hypernatremia in the geriatric population. Clin Interv Aging (2014) 0.81

Acute Symptomatic Seizures Caused by Electrolyte Disturbances. J Clin Neurol (2016) 0.80

Hypernatremia: correction rate and hemodialysis. Case Rep Med (2014) 0.80

Paranoid Adipsia-induced Severe Hypernatremia and Uremia treated with Hemodialysis. Electrolyte Blood Press (2013) 0.80

Dysnatraemias in the emergency room: Undetected, untreated, unknown? Wien Klin Wochenschr (2011) 0.80

Elevated sodium and dehydration stimulate inflammatory signaling in endothelial cells and promote atherosclerosis. PLoS One (2015) 0.80

Severity of community acquired hypernatremia is an independent predictor of mortality. Intern Emerg Med (2017) 0.79

Hypernatremia. N Engl J Med (2000) 0.79

New trends in hyperosmolar therapy? Curr Opin Crit Care (2013) 0.79

Transdermal fluid loss in severely burned patients. Ger Med Sci (2010) 0.79

Hypernatremia in patients with severe traumatic brain injury: a systematic review. Ann Intensive Care (2013) 0.78

The McGill Geriatric Lithium-Induced Diabetes Insipidus Clinical Study (McGLIDICS). Can J Psychiatry (2014) 0.78

Are the Dysnatremias a Permanent Threat to the Critically Ill Patients? J Clin Med Res (2015) 0.78

Electrolyte disorders and in-hospital mortality during prolonged heat periods: a cross-sectional analysis. PLoS One (2014) 0.78

Hypervolemic hypernatremia in patients recovering from acute kidney injury in the intensive care unit. Clin Exp Nephrol (2011) 0.77

Comparison of the Serum Electrolyte Levels among Patients Died and Survived in the Intensive Care Unit. Tanaffos (2012) 0.77

Hypernatemia : successful treatment. Electrolyte Blood Press (2006) 0.76

Diabetes Insipidus after Traumatic Brain Injury. J Clin Med (2015) 0.76

Wine Glass Sign and Empty Delta Sign: A Rare Imaging Presentation of Postpartum Encephalopathy in Dehydration. J Clin Diagn Res (2016) 0.75

Reversed portal flow: Clinical influence on the long-term outcomes in cirrhosis. World J Gastroenterol (2015) 0.75

The Development of Intensive Care Unit Acquired Hypernatremia Is Not Explained by Sodium Overload or Water Deficit: A Retrospective Cohort Study on Water Balance and Sodium Handling. Crit Care Res Pract (2016) 0.75

Increased mortality in hypernatremic burned patients. Ger Med Sci (2010) 0.75

Hypernatremia secondary to post-stroke hypodipsia: just add water! NDT Plus (2011) 0.75

Care of the stroke patient: routine management to lifesaving treatment options. Neurotherapeutics (2011) 0.75

Hypertonicity: Clinical entities, manifestations and treatment. World J Nephrol (2017) 0.75

Could dysnatremias play a role as independent factors to predict mortality in surgical critically ill patients? Medicine (Baltimore) (2017) 0.75

The Effects of Pre-Existing Hyponatremia and Subsequent-Developing Acute Kidney Injury on In-Hospital Mortality: A Retrospective Cohort Study. PLoS One (2016) 0.75

Severe Hypernatremia Caused by Acute Exogenous Salt Intake Combined with Primary Hypothyroidism. Electrolyte Blood Press (2016) 0.75

Risk factors for hospital-acquired hypernatremia among critically ill medical patients in a setting utilizing a preventive free water protocol: Do we need to do more? Indian J Crit Care Med (2013) 0.75

Cross-Sectional Positive Association of Serum Lipids and Blood Pressure With Serum Sodium Within the Normal Reference Range of 135-145 mmol/L. Arterioscler Thromb Vasc Biol (2016) 0.75

Extreme hypernatremic dehydration due to potential sodium intoxication: consequences and management for an infant with diarrhea at an urban intensive care unit in Bangladesh: a case report. J Med Case Rep (2015) 0.75

Clinical aspects of symptomatic hyponatremia. Endocr Connect (2016) 0.75

Severe hypernatraemia in obstructive uropathy. J R Soc Med (2001) 0.75

Physiological and biochemical changes associated with acute experimental dehydration in the desert adapted mouse, Peromyscus eremicus. Physiol Rep (2017) 0.75

Acquired hypernatremia in a general surgical Intensive Care Unit: Incidence and prognosis. Saudi J Anaesth (2016) 0.75

Does hypernatremia impact mortality in Toxic Epidermal Necrolysis? Ger Med Sci (2010) 0.75

Does lower urine-specific gravity predict decline in renal function and hypernatremia in older adults exposed to psychotropic medications? An exploratory analysis. Clin Kidney J (2015) 0.75

Heterogenous patterns of recovery of thirst in adult patients with adipsic diabetes insipidus. QJM (2015) 0.75

Prolonged hypernatremia triggered by hyperglycemic hyperosmolar state with coma: A case report. World J Nephrol (2015) 0.75

Treatment of hypernatremia in neonatal calves with diarrhea. Can Vet J (2007) 0.75

Hypernatremia secondary to soluble paracetamol use in an elderly man: a case report. Cases J (2009) 0.75

Insights about serum sodium behavior after 24 hours of continuous renal replacement therapy. Rev Bras Ter Intensiva (2016) 0.75

Hypernatremia. N Engl J Med (2000) 0.75

Does hyperglycemia in hypernatremic preterm infants increase the risk of intraventricular hemorrhage? J Perinatol (2016) 0.75

Thermoregulation and fluid balance during a 30-km march in 60- versus 80-year-old subjects. Age (Dordr) (2014) 0.75

Endocrinological disorders affecting neurosurgical patients: An intensivists perspective. Indian J Endocrinol Metab (2014) 0.75

Incidence, severity and prognosis associated with hypernatremia in dogs and cats. J Vet Intern Med (2015) 0.75

A Novel Practical Equation for Treatment of Emergent Hypernatremia and Dehydration Phase in Infants. J Res Pharm Pract (2017) 0.75

[Electrolyte disturbances in geriatric patients with focus on hyponatremia]. Z Gerontol Geriatr (2016) 0.75

Aspartame and Soft Drink-Mediated Neurotoxicity in Rats: Implication of Oxidative Stress, Apoptotic Signaling Pathways, Electrolytes and Hormonal Levels. Metab Brain Dis (2017) 0.75

NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality. J Am Soc Nephrol (2017) 0.75

Hypernatremic myopathy caused by a hypothalamic mixed germ cell tumor mimicking polymyositis. Clin Rheumatol (2006) 0.75

Severity of community acquired hypernatremia is an independent predictor of mortality: a matter of water balance and rate of correction. Intern Emerg Med (2017) 0.75

Emergency Neurological Life Support: Acute Non-traumatic Weakness. Neurocrit Care (2017) 0.75

Pediatric anterior visual pathway gliomas: trends in fluid and electrolyte dynamics and their management nuances. Childs Nerv Syst (2014) 0.75

Hyponatremia. N Engl J Med (2000) 11.31

Serum creatinine as an index of renal function: new insights into old concepts. Clin Chem (1992) 8.84

Management of life-threatening acid-base disorders. First of two parts. N Engl J Med (1998) 4.06

Captopril-induced functional renal insufficiency in patients with bilateral renal-artery stenoses or renal-artery stenosis in a solitary kidney. N Engl J Med (1983) 3.63

Management of life-threatening acid-base disorders. Second of two parts. N Engl J Med (1998) 2.69

Serum creatinine and renal function. Annu Rev Med (1988) 2.28

Assessing acid-base status in circulatory failure. Differences between arterial and central venous blood. N Engl J Med (1989) 2.04

Platinum nephrotoxicity. Am J Med (1978) 1.73

Admission serum magnesium level does not predict the hospital outcome of patients with acute myocardial infarction. Arch Intern Med (1996) 1.38

Changes in plasma potassium concentration during acute acid-base disturbances. Am J Med (1981) 1.32

Lactic acidosis. Kidney Int (1986) 1.17

Drug-induced hyperkalemia. Medicine (Baltimore) (1985) 1.16

Nonarrhythmogenicity of diuretic-induced hypokalemia. Its evidence in patients with uncomplicated hypertension. Arch Intern Med (1984) 1.09

Cisplatin nephrotoxicity. Miner Electrolyte Metab (1994) 1.05

Aiding fluid prescription for the dysnatremias. Intensive Care Med (1997) 0.99

Increased anion gap in metabolic alkalosis: the role of plasma-protein equivalency. N Engl J Med (1979) 0.98

Predominant tubulointerstitial lupus nephritis. Am J Kidney Dis (1996) 0.98

Nonsurgical treatment of severe hypertension due to renal-artery intimal fibroplasia by percutaneous transluminal angioplasty. N Engl J Med (1979) 0.97

Precordial ST-segment mapping. 2. Effects of oxygen inhalation on ischemic injury in patients with acute myocardial infarction. Circulation (1976) 0.96

Severe lactic acidosis as a presenting feature of pheochromocytoma. Am J Kidney Dis (1987) 0.94

Percutaneous transluminal renal angioplasty in management of atherosclerotic renovascular hypertension: results in 100 patients. Hypertension (1989) 0.94

Endothelin-1 stimulates the Na+/H+ and Na+/HCO3- transporters in rabbit renal cortex. Kidney Int (1992) 0.94

Percutaneous transluminal renal angioplasty. A potentially effective treatment for preservation of renal function. Arch Intern Med (1982) 0.93

Enalapril-associated anemia in renal transplant recipients treated for hypertension. Am J Kidney Dis (1991) 0.92

Hypochloremia as a consequence of anion gap metabolic acidosis. J Lab Clin Med (1984) 0.89

Admission serum potassium in patients with acute myocardial infarction: its correlates and value as a determinant of in-hospital outcome. Chest (2000) 0.88

Spurious assessment of acid-base status due to dilutional effect of heparin. Am J Med (1985) 0.87

The maladaptive renal response to secondary hypocapnia during chronic HCl acidosis in the dog. J Clin Invest (1977) 0.86

Influence of steady-state alterations in acid-base equilibrium on the fate of administered bicarbonate in the dog. J Clin Invest (1983) 0.85

Techniques for isolation of brush-border and basolateral membrane vesicles from dog kidney cortex. Biochim Biophys Acta (1989) 0.84

Changes in the plasma anion gap during chronic metabolic acid-base disturbances. Am J Physiol (1978) 0.84

Stimulation of basolateral Na(+)-HCO3- cotransporter by angiotensin II in rabbit renal cortex. Am J Physiol (1993) 0.84

A redefinition of normal acid-base equilibrium in man: carbon dioxide tension as a key determinant of normal plasma bicarbonate concentration. Kidney Int (1979) 0.83

Percutaneous transluminal angioplasty for severe renovascular hypertension due to renal-artery medial fibroplasia. Lancet (1979) 0.82

Regulation of acid-base equilibrium in chronic hypocapnia. Evidence that the response of the kidney is not geared to the defense of extracellular (H+). J Clin Invest (1976) 0.82

Transcriptional regulation of the human iNOS gene by IL-1beta in endothelial cells. Mol Med (2001) 0.81

Pregnancy in women with renal disease and moderate renal insufficiency. Am J Med (1985) 0.81

The renal response to chronic mineral acid feeding: a re-examination of the role of systemic pH. Kidney Int (1986) 0.81

Effect of chronic respiratory acidosis on urinary calcium excretion in the dog. Kidney Int (1990) 0.80

Transcriptional regulation of the human iNOS gene in vascular-smooth-muscle cells and macrophages: evidence for tissue specificity. Biochem Biophys Res Commun (1996) 0.80

Cl(-)-dependent ATP-driven H+ transport in rabbit renal cortical endosomes. Am J Physiol (1988) 0.80

H+/Ca2+ exchange in rabbit renal cortical endosomes. J Membr Biol (1989) 0.79

Adaptation of rabbit renal cortical Na+-H+ exchange activity in chronic hypocapnia. Am J Physiol (1989) 0.79

Na(+)-H+ exchange, but not Na(+)-K(+)-ATPase, is present in endosome-enriched microsomes from rabbit renal cortex. Am J Physiol (1990) 0.79

Proximal regulatory elements and nuclear activities required for transcription of the human Na+/H+ exchanger (NHE-1) gene. Biochim Biophys Acta (1994) 0.78

Renal acidification during chronic hypercapnia in the conscious dog. Pflugers Arch (1986) 0.78

CREB transcription factor modulates Bcl2 transcription in response to C5a in HL-60-derived neutrophils. Eur J Clin Invest (2006) 0.78

Independence of the acute acid-buffering response from endogenous parathyroid hormone. Am J Physiol (1982) 0.77

Approach to patients with acid-base disorders. Respir Care (2001) 0.77

Stimulation of canine kidney BBMV ATPase activity by acidic pH in the presence of Zn2+: an ATPase activity distinct from transport ATPases and alkaline phosphatase that may be an ecto-ATPase. Membr Biochem (1991) 0.77

The effect of potassium ion depletion on postinfarction canine cardiac arrhythmias. Circulation (1988) 0.77

What are the metabolic complications of diuretic treatment? Geriatrics (1982) 0.77

3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors upregulate inducible NO synthase expression and activity in vascular smooth muscle cells. Hypertension (2001) 0.76

Effect of chronic respiratory acidosis on calcium metabolism in the rat. J Lab Clin Med (1995) 0.76

Maladaptive renal response to secondary hypercapnia in chronic metabolic alkalosis. Am J Physiol (1980) 0.76

Rat kidney band 3 mRNA modulation in chronic respiratory acidosis. Am J Physiol (1991) 0.76

Percutaneous transluminal renal angioplasty in nonatherosclerotic renovascular hypertension. Long-term results. Hypertension (1985) 0.75

Experimental renal failure in the rat modulates cardiac Na,K-ATPase alpha 2 mRNA but not protein. J Am Soc Nephrol (1994) 0.75

Ventilatory response to chronic metabolic acidosis and alkalosis in the dog. J Appl Physiol Respir Environ Exerc Physiol (1984) 0.75

Percutaneous transluminal renal angioplasty. Chest (1982) 0.75

PTRA in the treatment of renovascular hypertension. Hosp Pract (Off Ed) (1981) 0.75

Ventricular ectopy and diuretic-induced hypokalemia. An alleged association in need of clinical and experimental scrutiny. Chest (1986) 0.75

Mineralocorticoid-stimulated renal acidification: the critical role of dietary sodium. Kidney Int (1986) 0.75

Respiratory acid-base disorders. Hosp Pract (1980) 0.75

Influence of chronic respiratory acid-base disorders on acute CO2 titration curve. J Appl Physiol (1985) (1985) 0.75

Hyperkalemia-like ECG changes simulating acute myocardial infarction in a patient with hypokalemia undergoing potassium replacement. J Electrocardiol (1989) 0.75

Effect of natural variations in PaCO2 on plasma [HCO3-] in dogs: a redefinition of normal. Am J Physiol (1979) 0.75

Influence of chronic metabolic acid-base disorders on the acute CO2 titration curve. J Appl Physiol Respir Environ Exerc Physiol (1983) 0.75

A comparison of the safety of therapeutically equivalent doses of isradipine and diltiazem for treatment of essential hypertension. Am J Hypertens (1992) 0.75

Enalapril in the management of hypertension associated with renal artery stenosis. J Clin Pharmacol (1987) 0.75

Marked dilutional acidosis complicating management of right ventricular myocardial infarction. Am J Kidney Dis (1997) 0.75

Percutaneous transluminal renal angioplasty in the treatment of unilateral atherosclerotic renovascular hypertension. Am J Med (1981) 0.75

Metabolic alkalosis due to absorption of "nonabsorbable" antacids. Am J Med (1983) 0.75

Role of C/EBP proteins in hepatic and vascular smooth muscle transcription of human NHE1 gene. Am J Physiol (1995) 0.75

Secondary hypocapnia fails to protect "whole body" intracellular pH during chronic HCl-acidosis in the dog. Kidney Int (1983) 0.75

Effect of sulfhydryl compounds on ATP-stimulated H+ transport and Cl- uptake in rabbit renal cortical endosomes. J Membr Biol (1991) 0.75

Arteriovenous acid-base disparity in circulatory failure: studies on mechanism. Am J Physiol (1989) 0.75

Regulation of acid-base equilibrium in chronic hypercapnia. Kidney Int (1985) 0.75