PubRank

P J Meier

Author PubWeight™ 164.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver. J Biol Chem 1998 2.72
2 Acute heart transplant rejection due to Saint John's wort. Lancet 2000 2.71
3 Molecular pathogenesis of cholestasis. N Engl J Med 1998 2.68
4 The superfamily of organic anion transporting polypeptides. Biochim Biophys Acta 2003 2.53
5 Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver. J Cell Biol 1984 2.47
6 Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology 2001 2.36
7 Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system. Proc Natl Acad Sci U S A 1991 2.11
8 The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions. Clin Pharmacol Ther 2001 2.10
9 Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter. J Clin Invest 1994 1.98
10 St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4. Clin Pharmacol Ther 2000 1.89
11 Epidemiology of drug exposure and adverse drug reactions in two swiss departments of internal medicine. Br J Clin Pharmacol 2000 1.82
12 Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver. Gastroenterology 1995 1.66
13 Transient cortical blindness and bioccipital brain lesions in two patients with acute intermittent porphyria. Ann Intern Med 1995 1.58
14 Interaction between grapefruit juice and midazolam in humans. Clin Pharmacol Ther 1995 1.53
15 Expression cloning of a rat liver Na(+)-independent organic anion transporter. Proc Natl Acad Sci U S A 1994 1.51
16 Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter. Mol Endocrinol 2002 1.49
17 Organic anion-transporting polypeptides mediate transport of opioid peptides across blood-brain barrier. J Pharmacol Exp Ther 2000 1.46
18 Functional expression cloning of the canalicular sulfate transport system of rat hepatocytes. J Biol Chem 1994 1.46
19 Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver. Gastroenterology 2000 1.46
20 Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration. Am J Physiol 1999 1.45
21 Hepatic uptake of the magnetic resonance imaging contrast agent gadoxetate by the organic anion transporting polypeptide Oatp1. J Pharmacol Exp Ther 1999 1.44
22 Transport function and hepatocellular localization of mrp6 in rat liver. Mol Pharmacol 2000 1.38
23 Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver. Gastroenterology 2001 1.32
24 Hepatic transport of bile salts. Semin Liver Dis 2000 1.31
25 Expression of members of the multidrug resistance protein family in human term placenta. Am J Physiol Regul Integr Comp Physiol 2000 1.28
26 Organic anion transporting polypeptides expressed in liver and brain mediate uptake of microcystin. Toxicol Appl Pharmacol 2005 1.27
27 Expression of the hepatocyte Na+/bile acid cotransporter in Xenopus laevis oocytes. J Biol Chem 1990 1.27
28 Immunologic distribution of an organic anion transport protein in rat liver and kidney. Am J Physiol 1996 1.22
29 Mechanisms of taurocholate transport in canalicular and basolateral rat liver plasma membrane vesicles. Evidence for an electrogenic canalicular organic anion carrier. J Biol Chem 1984 1.22
30 Isolation and characterization of rough endoplasmic reticulum associated with mitochondria from normal rat liver. Biochim Biophys Acta 1981 1.22
31 Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain. J Histochem Cytochem 1999 1.20
32 Characterization of inducible nature of MRP3 in rat liver. Am J Physiol Gastrointest Liver Physiol 2000 1.18
33 Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain. Proc Natl Acad Sci U S A 1997 1.18
34 In situ localization of the hepatocytic Na+/Taurocholate cotransporting polypeptide in rat liver. Gastroenterology 1994 1.16
35 Parallel decrease of Na(+)-taurocholate cotransport and its encoding mRNA in primary cultures of rat hepatocytes. Hepatology 1993 1.15
36 Localization and function of the organic anion-transporting polypeptide Oatp2 in rat liver. Gastroenterology 1999 1.14
37 Transport of bile acids in hepatic and non-hepatic tissues. J Exp Biol 2001 1.14
38 Drug uptake systems in liver and kidney. Curr Drug Metab 2003 1.14
39 Functional characterization of the basolateral rat liver organic anion transporting polypeptide. Hepatology 1994 1.13
40 Hepatic transport systems regulating pHi, cell volume, and bile secretion. Annu Rev Physiol 1992 1.13
41 Identification of steroid sulfate transport processes in the human mammary gland. J Clin Endocrinol Metab 2003 1.13
42 Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3. Pflugers Arch 2001 1.13
43 Mechanisms of cholestasis. Clin Liver Dis 2000 1.11
44 Multispecificity of Na+-dependent taurocholate uptake in basolateral (sinusoidal) rat liver plasma membrane vesicles. J Pharmacol Exp Ther 1989 1.11
45 alpha-Amanitin uptake into hepatocytes. Identification of hepatic membrane transport systems used by amatoxins. J Biol Chem 1986 1.10
46 Expression of the bile salt export pump is maintained after chronic cholestasis in the rat. Gastroenterology 2000 1.10
47 Oatp2 mediates bidirectional organic solute transport: a role for intracellular glutathione. Mol Pharmacol 2000 1.09
48 Phylogenic and ontogenic expression of hepatocellular bile acid transport. Proc Natl Acad Sci U S A 1993 1.08
49 Hepatic uptake of cholecystokinin octapeptide by organic anion-transporting polypeptides OATP4 and OATP8 of rat and human liver. Gastroenterology 2001 1.07
50 Isolation of a subfraction of rough endoplasmic reticulum closely associated with mitochondria. Evidence for its role in cytochrome P450 synthesis. Exp Cell Res 1978 1.06
51 Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells. Am J Physiol 1999 1.06
52 Chlorambucil-taurocholate is transported by bile acid carriers expressed in human hepatocellular carcinomas. Gastroenterology 1997 1.05
53 Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier. J Pharmacol Exp Ther 2001 1.04
54 Direct energization of bile acid transport into plant vacuoles. J Biol Chem 1993 1.04
55 Multispecific amphipathic substrate transport by an organic anion transporter of human liver. J Hepatol 1996 1.03
56 Evidence for carrier-mediated chloride/bicarbonate exchange in canalicular rat liver plasma membrane vesicles. J Clin Invest 1985 1.03
57 Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes. Hepatology 2001 1.02
58 Expression of the hepatocellular chloride-dependent sulfobromophthalein uptake system in Xenopus laevis oocytes. J Clin Invest 1991 1.02
59 Identification of glutathione as a driving force and leukotriene C4 as a substrate for oatp1, the hepatic sinusoidal organic solute transporter. J Biol Chem 1998 1.02
60 Rat hepatocytes exhibit basolateral Na+/HCO3- cotransport. J Clin Invest 1989 1.01
61 Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver. J Pharmacol Exp Ther 1996 1.01
62 Identification of thyroid hormone transporters. Biochem Biophys Res Commun 1999 1.00
63 Differential regulation of hepatic bile salt and organic anion transporters in pregnant and postpartum rats and the role of prolactin. Hepatology 2001 1.00
64 Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes. Am J Physiol 1991 1.00
65 Isolation and characterization of the putative canalicular bile salt transport system of rat liver. J Biol Chem 1987 0.99
66 Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (rlst-1) in rat liver. FEBS Lett 2000 0.99
67 Dehydroepiandrosterone sulfate (DHEAS): identification of a carrier protein in human liver and brain. FEBS Lett 1998 0.99
68 Hepatic monooxygenase activities in subjects with a genetic defect in drug oxidation. Gastroenterology 1983 0.98
69 Sinusoidal (basolateral) bile salt uptake systems of hepatocytes. Semin Liver Dis 1996 0.98
70 Ethinylestradiol treatment induces multiple canalicular membrane transport alterations in rat liver. J Clin Invest 1993 0.98
71 Multiple factors regulate the rat liver basolateral sodium-dependent bile acid cotransporter gene promoter. J Biol Chem 1996 0.97
72 Partial maintenance of taurocholate uptake by adult rat hepatocytes cultured in a collagen sandwich configuration. Pharm Res 1998 0.97
73 Rifamycin SV and rifampicin exhibit differential inhibition of the hepatic rat organic anion transporting polypeptides, Oatp1 and Oatp2. Hepatology 2000 0.96
74 ATP-dependent bile-salt transport in canalicular rat liver plasma-membrane vesicles. Biochem J 1992 0.96
75 Dose-dependent toxicity of diphenhydramine overdose. Hum Exp Toxicol 2000 0.96
76 Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1 alpha. J Biol Chem 2001 0.95
77 Characterization of an organic anion-transporting polypeptide (OATP-B) in human placenta. J Clin Endocrinol Metab 2002 0.94
78 Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes. Biochem J 1996 0.93
79 The risks and benefits of distal first metatarsal osteotomies. Foot Ankle 1985 0.92
80 Polyspecific organic anion transporting polypeptides mediate hepatic uptake of amphipathic type II organic cations. J Pharmacol Exp Ther 1999 0.92
81 Functional reconstitution of the canalicular bile salt transport system of rat liver. Proc Natl Acad Sci U S A 1988 0.92
82 Preparation of basolateral (sinusoidal) and canalicular plasma membrane vesicles for the study of hepatic transport processes. Methods Enzymol 1990 0.92
83 cAMP increases liver Na+-taurocholate cotransport by translocating transporter to plasma membranes. Am J Physiol 1997 0.92
84 Molecular regulation of hepatocellular transport systems in cholestasis. J Hepatol 1999 0.91
85 Temporal expression profiles of organic anion transport proteins in placenta and fetal liver of the rat. Am J Physiol Regul Integr Comp Physiol 2004 0.91
86 Identification of a single sinusoidal bile salt uptake system in skate liver. Am J Physiol 1987 0.91
87 Stable expression and functional characterization of a Na+-taurocholate cotransporting green fluorescent protein in human hepatoblastoma HepG2 cells. Cytotechnology 2000 0.90
88 Arterial and venous pharmacokinetics of intravenous heroin in subjects who are addicted to narcotics. Clin Pharmacol Ther 2001 0.90
89 Effect of phenobarbital on the expression of bile salt and organic anion transporters of rat liver. J Hepatol 2001 0.90
90 Effects of the benzodiazepine receptor antagonist flumazenil in hepatic encephalopathy in humans. Gastroenterology 1989 0.90
91 Transport of temocaprilat into rat hepatocytes: role of organic anion transporting polypeptide. J Pharmacol Exp Ther 1998 0.90
92 Expression of rat renal sulfate transport systems in Xenopus laevis oocytes. Functional characterization and molecular identification. J Biol Chem 1994 0.90
93 The choroid plexus epithelium is the site of the organic anion transport protein in the brain. Proc Natl Acad Sci U S A 1997 0.90
94 Na-H exchange in rat liver basolateral but not canalicular plasma membrane vesicles. Am J Physiol 1986 0.90
95 Demonstration of a transcellular vesicle pathway for biliary excretion of inulin in rat liver. Gastroenterology 1986 0.90
96 Multispecific anion exchange in basolateral (sinusoidal) rat liver plasma membrane vesicles. Am J Physiol 1986 0.90
97 Properties of the canalicular bile acid transport system in rat liver. Biochem J 1987 0.89
98 Insulin regulates the expression of the insulin-like growth factor binding protein 2 mRNA in rat hepatocytes. Mol Endocrinol 1990 0.89
99 Functional expression of the rat liver canalicular isoform of the multidrug resistance-associated protein. FEBS Lett 1997 0.89
100 Stable inducible expression of a functional rat liver organic anion transport protein in HeLa cells. J Biol Chem 1995 0.88
101 Expression and characterization of a functional rat liver Na+ bile acid cotransport system in COS-7 cells. Am J Physiol 1994 0.88
102 Differential interaction of bile acids from patients with inborn errors of bile acid synthesis with hepatocellular bile acid transporters. Eur J Biochem 1997 0.87
103 Characterizing mechanisms of hepatic bile acid transport utilizing isolated membrane vesicles. Methods Enzymol 1990 0.87
104 The peptide-based thrombin inhibitor CRC 220 is a new substrate of the basolateral rat liver organic anion-transporting polypeptide. Hepatology 1996 0.87
105 Bufuralol metabolism in human liver: a sensitive probe for the debrisoquine-type polymorphism of drug oxidation. Eur J Clin Invest 1984 0.86
106 Differential expression of basolateral and canalicular organic anion transporters during regeneration of rat liver. Gastroenterology 1999 0.85
107 Bile acids modulate the interferon signalling pathway. Hepatology 1999 0.85
108 Hepatocellular transport of bile acids. Evidence for distinct subcellular localizations of electrogenic and ATP-dependent taurocholate transport in rat hepatocytes. J Biol Chem 1994 0.85
109 Effect of obstructive cholestasis on membrane traffic and domain-specific expression of plasma membrane proteins in rat liver parenchymal cells. Hepatology 1994 0.84
110 Characterization of the mouse bile salt export pump overexpressed in the baculovirus system. Hepatology 2001 0.84
111 Cholate uptake in basolateral rat liver plasma membrane vesicles and in liposomes. Biochim Biophys Acta 1990 0.84
112 Extrahepatic obstructive cholestasis reverses the bile salt secretory polarity of rat hepatocytes. J Clin Invest 1989 0.84
113 Regulation of bile salt export pump mRNA levels by dexamethasone and osmolarity in cultured rat hepatocytes. Biol Chem 1999 0.83
114 Functional analysis and androgen-regulated expression of mouse organic anion transporting polypeptide 1 (Oatp1) in the kidney. Biochim Biophys Acta 2001 0.83
115 Evidence for the presence of a phosphatidylcholine translocator in isolated rat liver canalicular plasma membrane vesicles. J Biol Chem 1993 0.83
116 Organic anion transport across the choroid plexus. Microsc Res Tech 2001 0.83
117 Substrate specificity of the rat liver Na(+)-bile salt cotransporter in Xenopus laevis oocytes and in CHO cells. Am J Physiol 1998 0.83
118 Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides. J Pharmacol Exp Ther 2001 0.83
119 Hepatocellular transport proteins and their role in liver disease. World J Gastroenterol 2001 0.82
120 Identification and characterization of a basolateral dicarboxylate/cholate antiport system in rat hepatocytes. Am J Physiol 1995 0.82
121 Identification and functional characterization of the promoter region of the human organic anion transporting polypeptide gene. Hepatology 1997 0.81
122 Effect of ursodeoxycholic acid on the impairment induced by maternal cholestasis in the rat placenta-maternal liver tandem excretory pathway. J Pharmacol Exp Ther 2003 0.81
123 Decreased Na+-dependent taurocholate uptake and low expression of the sinusoidal Na+-taurocholate cotransporting protein (Ntcp) in livers of mdr2 P-glycoprotein-deficient mice. J Hepatol 1999 0.81
124 Characterization of the transport properties of organic anion transporting polypeptide 1 (oatp1) and Na(+)/taurocholate cotransporting polypeptide (Ntcp): comparative studies on the inhibitory effect of their possible substrates in hepatocytes and cDNA-transfected COS-7 cells. J Pharmacol Exp Ther 2000 0.81
125 Uptake of the mycotoxin ochratoxin A in liver cells occurs via the cloned organic anion transporting polypeptide. J Pharmacol Exp Ther 1996 0.81
126 Inhibition of taurocholate efflux from rat hepatic canalicular membrane vesicles by glutathione disulfide. FEBS Lett 1987 0.81
127 Prolactin increases hepatic Na+/taurocholate co-transport activity and messenger RNA post partum. Biochem J 1994 0.80
128 Sodium taurocholate cotransporting polypeptide is a serine, threonine phosphoprotein and is dephosphorylated by cyclic adenosine monophosphate. Hepatology 1998 0.80
129 The effect of changes in the fluid state of rat liver plasma membrane on the transport of taurocholate. Hepatology 1987 0.80
130 Hepatocyte performance on different crystallographic faces of rutile. Biomaterials 2003 0.80
131 Mechanism and subcellular site of bilirubin diglucuronide formation in rat liver. J Biol Chem 1984 0.79
132 Differential regulation of insulin-like growth factor binding protein (IGFBP)-2 mRNA in liver and bone cells by insulin and retinoic acid in vitro. FEBS Lett 1992 0.79
133 Anion transport in basolateral (sinusoidal) liver plasma-membrane vesicles of the little skate (Raja erinacea). Biochem J 1987 0.79
134 Pyridoxine-responsive primary acquired sideroblastic anaemia. In vitro and in vivo effects of vitamin B6 on decreased 5-aminolaevulinate synthase activity. Scand J Haematol 1982 0.79
135 Expression of sodium-independent organic anion uptake systems of skate liver in Xenopus laevis oocytes. Am J Physiol 1995 0.79
136 Transport mechanisms for cationic drugs and proteins in kidney, liver and intestine: implication for drug interactions and cell-specific drug delivery. Nephrol Dial Transplant 1999 0.79
137 Differential effects of microsomal enzyme-inducing chemicals on the hepatic expression of rat organic anion transporters, OATP1 and OATP2. Hepatology 2001 0.79
138 Case report: reversible QT prolongation with torsades de pointes in a patient with pimozide intoxication. Am J Med Sci 1995 0.79
139 Opposite effects of lornoxicam co-administration on phenprocoumon pharmacokinetics and pharmacodynamics. Eur J Clin Pharmacol 1999 0.78
140 Expression of a rat liver phosphatidylcholine translocator in Xenopus laevis oocytes. Hepatology 1996 0.78
141 Bile acid and xenobiotic transporters in liver. Curr Opin Cell Biol 1998 0.78
142 Assignment of the human organic anion transporting polypeptide (OATP) gene to chromosome 12p12 by fluorescence in situ hybridization. J Hepatol 1996 0.78
143 Regulation of hepatocyte bile salt transporters during hepatic regeneration. Am J Physiol 1997 0.78
144 Induction of drug-metabolizing enzymes by phenobarbitone: structural and biochemical aspects. Ciba Found Symp 1980 0.78
145 "Buffalo hump" in HIV-1 infection. Lancet 1998 0.78
146 Plasma and hepatic carnitine and coenzyme A pools in a patient with fatal, valproate induced hepatotoxicity. Gut 1995 0.78
147 Advances in hepatic transport: molecular mechanisms, genetic disorders, and treatment. A summary of the 1998 AASLD single topic conference. Hepatology 1998 0.77
148 Identification of sodium-dependent and sodium-independent dicarboxylate transport systems in rat liver basolateral membrane vesicles. Pflugers Arch 1992 0.77
149 Safety of liver donation after fatal intoxication with the tricyclic antidepressant trimipramine. Transplantation 1996 0.77
150 Solvent isotope effect on bile formation in the rat. Biochem J 1995 0.77
151 Functional analysis of candidate ABC transporter proteins for sitosterol transport. Biochim Biophys Acta 2002 0.77
152 Polar surface distribution of type II insulin-like growth factor receptor in rat hepatocytes. Mol Cell Endocrinol 1990 0.77
153 Biosynthesis of rat liver cytochrome P-450 in mitochondria-associated rough endoplasmic reticulum and in rough microsomes in vivo. J Biol Chem 1984 0.76
154 Separation of hepatocyte plasma membrane domains by free flow electrophoresis. Anal Biochem 1989 0.76
155 [Alcohol, alcoholism and drugs]. Schweiz Med Wochenschr 1985 0.76
156 Taurocholate induces preferential release of phosphatidylcholine from rat liver canalicular vesicles. Liver 1998 0.75
157 Hepatic bile salt flux does not modulate level and activity of the sinusoidal Na+-taurocholate cotransporter (ntcp) in rats. J Hepatol 1997 0.75
158 Bile duct ligation-induced redistribution of canalicular antigen in rat hepatocyte plasma membranes demonstrated by immunogold quantitation. Histochemistry 1990 0.75
159 [Acute poisoning with thioridazine]. Dtsch Med Wochenschr 1996 0.75
160 [Aspirin against aging? For whom and how much?]. Ther Umsch 1990 0.75
161 No clinically relevant effect of lornoxicam intake on acenocoumarol pharmacokinetics and pharmacodynamics. Eur J Clin Pharmacol 1999 0.75
162 Calcium transport in plasma membrane subfractions of rat liver. Prog Clin Biol Res 1988 0.75
163 [Gastrointestinal and hepatic side effects of drugs]. Ther Umsch 1987 0.75
164 [Acquired, vitamin B6-responsive, primary sideroblastic anemia, an enzyme deficiency in heme synthesis]. Schweiz Med Wochenschr 1981 0.75
165 [Role of nuclear receptors in hepatic and intestinal drug transport]. Dtsch Med Wochenschr 2003 0.75
166 Carrier-mediated hepatic uptake of peptidic endothelin antagonists in rats. J Pharmacol Exp Ther 1999 0.75
167 Uptake of 3 alpha, 7 alpha, 12 alpha-trihydroxy-24-nor-5 beta-cholan-23-sulfonate into isolated rat hepatocytes by three transport systems. J Lipid Res 1997 0.75
168 [Drug therapy of pain]. Ther Umsch 1989 0.75
169 The effect of ethanol and calcium on fluid state of plasma membranes of rat hepatocytes. Alcohol 1985 0.75
170 [Clinico-pharmacological case (2). Bradycardia and ventricular tachycardia of the torsades de pointes type as a side effect of vasopressin: 3 case reports]. Praxis (Bern 1994) 1996 0.75
171 [Clinically significant inherited differences in the mode of action of drugs]. Schweiz Med Wochenschr 1982 0.75
172 Surveillance of occupational illness through a national poison control center: an approach to reach small-scale enterprises? Int Arch Occup Environ Health 1994 0.75
173 [Drug therapy in liver disease]. Schweiz Med Wochenschr 1982 0.75