Published in Nat Cell Biol on July 01, 2000
Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin. J Cell Biol (2005) 4.75
Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly. Proc Natl Acad Sci U S A (2005) 2.75
Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells. EMBO Rep (2001) 2.48
Actin-based motility of intracellular microbial pathogens. Microbiol Mol Biol Rev (2001) 2.17
Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex. Biochem J (2004) 2.08
N-wasp and the arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapses. J Biol Chem (2008) 2.05
The Dictyostelium CARMIL protein links capping protein and the Arp2/3 complex to type I myosins through their SH3 domains. J Cell Biol (2001) 2.05
Cellular gene expression survey of vaccinia virus infection of human HeLa cells. J Virol (2003) 1.97
N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway. Nat Cell Biol (2011) 1.92
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Subversion of the actin cytoskeleton during viral infection. Nat Rev Microbiol (2011) 1.77
Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension. J Cell Biol (2002) 1.72
Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA. Mol Cell Biol (2003) 1.67
Microarray analysis reveals characteristic changes of host cell gene expression in response to attenuated modified vaccinia virus Ankara infection of human HeLa cells. J Virol (2004) 1.65
Regulated exocytosis in neuroendocrine cells: a role for subplasmalemmal Cdc42/N-WASP-induced actin filaments. Mol Biol Cell (2003) 1.58
The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility. Nature (2009) 1.53
Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP. Blood (2009) 1.52
Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation. J Cell Sci (2009) 1.51
Disruption of the Rickettsia rickettsii Sca2 autotransporter inhibits actin-based motility. Infect Immun (2010) 1.49
A two-tiered mechanism by which Cdc42 controls the localization and activation of an Arp2/3-activating motor complex in yeast. J Cell Biol (2001) 1.44
WIP regulates the stability and localization of WASP to podosomes in migrating dendritic cells. Curr Biol (2006) 1.43
Regulation of protein transport from the Golgi complex to the endoplasmic reticulum by CDC42 and N-WASP. Mol Biol Cell (2002) 1.42
Arp2/3-mediated actin-based motility: a tail of pathogen abuse. Cell Host Microbe (2013) 1.40
Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly. J Cell Biol (2004) 1.39
Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization. Mol Cell Biol (2008) 1.34
Protein analysis of purified respiratory syncytial virus particles reveals an important role for heat shock protein 90 in virus particle assembly. Mol Cell Proteomics (2010) 1.27
c-Abl phosphorylates Dok1 to promote filopodia during cell spreading. J Cell Biol (2004) 1.26
Role of the WASP family proteins for Mycobacterium marinum actin tail formation. Proc Natl Acad Sci U S A (2005) 1.25
CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family. Proc Natl Acad Sci U S A (2001) 1.24
Inhibiting the Arp2/3 complex limits infection of both intracellular mature vaccinia virus and primate lentiviruses. Mol Biol Cell (2004) 1.21
Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes. Mol Biol Cell (2002) 1.19
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Vaccinia virus A36R membrane protein provides a direct link between intracellular enveloped virions and the microtubule motor kinesin. J Virol (2004) 1.12
The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions. J Cell Biol (2003) 1.12
Requirement for a complex of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein in podosome formation in macrophages. J Immunol (2007) 1.11
Bacterial actin assembly requires toca-1 to relieve N-wasp autoinhibition. Cell Host Microbe (2008) 1.09
Requirement for formin-induced actin polymerization during spread of Shigella flexneri. Infect Immun (2009) 1.08
Mapping and functional analysis of interaction sites within the cytoplasmic domains of the vaccinia virus A33R and A36R envelope proteins. J Virol (2003) 1.07
A gamma-herpesvirus glycoprotein complex manipulates actin to promote viral spread. PLoS One (2008) 1.06
Molecular basis of the intracellular spreading of Shigella. Infect Immun (2001) 1.05
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A WASp-binding type II phosphatidylinositol 4-kinase required for actin polymerization-driven endosome motility. J Cell Biol (2005) 1.02
Differences in virus-induced cell morphology and in virus maturation between MVA and other strains (WR, Ankara, and NYCBH) of vaccinia virus in infected human cells. J Virol (2003) 1.00
F11-mediated inhibition of RhoA signalling enhances the spread of vaccinia virus in vitro and in vivo in an intranasal mouse model of infection. PLoS One (2009) 0.99
WIP provides an essential link between Nck and N-WASP during Arp2/3-dependent actin polymerization. Curr Biol (2013) 0.98
Mutagenesis of the Shigella flexneri autotransporter IcsA reveals novel functional regions involved in IcsA biogenesis and recruitment of host neural Wiscott-Aldrich syndrome protein. J Bacteriol (2008) 0.97
Stoichiometry of Nck-dependent actin polymerization in living cells. J Cell Biol (2012) 0.97
Vaccinia protein F12 has structural similarity to kinesin light chain and contains a motor binding motif required for virion export. PLoS Pathog (2010) 0.97
Visualization of spatially and temporally regulated N-WASP activity during cytoskeletal reorganization in living cells. Proc Natl Acad Sci U S A (2004) 0.97
Helicobacter pylori CagA induces AGS cell elongation through a cell retraction defect that is independent of Cdc42, Rac1, and Arp2/3. Infect Immun (2006) 0.95
An E2-F12 complex is required for intracellular enveloped virus morphogenesis during vaccinia infection. Cell Microbiol (2009) 0.94
EspF Interacts with nucleation-promoting factors to recruit junctional proteins into pedestals for pedestal maturation and disruption of paracellular permeability. Infect Immun (2008) 0.94
Regulation of cell death by recycling endosomes and golgi membrane dynamics via a pathway involving Src-family kinases, Cdc42 and Rab11a. Mol Biol Cell (2009) 0.94
How WASP regulates actin polymerization. J Cell Biol (2000) 0.93
Effects of ectopically expressed neuronal Wiskott-Aldrich syndrome protein domains on Rickettsia rickettsii actin-based motility. Infect Immun (2003) 0.92
The actin nucleator WASp is required for myoblast fusion during adult Drosophila myogenesis. Development (2011) 0.91
Adenovirus E4orf4 hijacks rho GTPase-dependent actin dynamics to kill cells: a role for endosome-associated actin assembly. Mol Biol Cell (2006) 0.91
A reciprocal interdependence between Nck and PI(4,5)P(2) promotes localized N-WASp-mediated actin polymerization in living cells. Mol Cell (2009) 0.90
Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin. Mol Biol Cell (2007) 0.89
Structure-function analysis of the WIP role in T cell receptor-stimulated NFAT activation: evidence that WIP-WASP dissociation is not required and that the WIP NH2 terminus is inhibitory. J Biol Chem (2007) 0.88
Calmodulin interaction with hEAG1 visualized by FRET microscopy. PLoS One (2010) 0.86
A36-dependent actin filament nucleation promotes release of vaccinia virus. PLoS Pathog (2013) 0.85
The enteropathogenic E. coli effector EspH promotes actin pedestal formation and elongation via WASP-interacting protein (WIP). Cell Microbiol (2012) 0.84
The host phosphoinositide 5-phosphatase SHIP2 regulates dissemination of vaccinia virus. J Virol (2011) 0.84
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Integration of signaling and cytoskeletal remodeling by Nck in directional cell migration. Bioarchitecture (2013) 0.83
Loss of cytoskeletal transport during egress critically attenuates ectromelia virus infection in vivo. J Virol (2012) 0.82
The Chlamydia effector TarP mimics the mammalian leucine-aspartic acid motif of paxillin to subvert the focal adhesion kinase during invasion. J Biol Chem (2014) 0.82
The non-canonical roles of clathrin and actin in pathogen internalization, egress and spread. Nat Rev Microbiol (2013) 0.81
WASP-interacting protein is important for actin filament elongation and prompt pseudopod formation in response to a dynamic chemoattractant gradient. Mol Biol Cell (2006) 0.81
Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread. PLoS Pathog (2016) 0.81
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WIP remodeling actin behind the scenes: how WIP reshapes immune and other functions. Int J Mol Sci (2012) 0.78
Enteropathogenic Escherichia coli and vaccinia virus do not require the family of WASP-interacting proteins for pathogen-induced actin assembly. Infect Immun (2012) 0.78
EtpE Binding to DNase X Induces Ehrlichial Entry via CD147 and hnRNP-K Recruitment, Followed by Mobilization of N-WASP and Actin. MBio (2015) 0.78
Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages. J Cell Sci (2014) 0.78
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Impact of dynasore an inhibitor of dynamin II on Shigella flexneri infection. PLoS One (2013) 0.77
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Identification of Shigella flexneri IcsA residues affecting interaction with N-WASP, and evidence for IcsA-IcsA co-operative interaction. PLoS One (2013) 0.76
A role for the small GTPase Rac1 in vaccinia actin-based motility. Small GTPases (2014) 0.76
WIP and WICH/WIRE co-ordinately control invadopodium formation and maturation in human breast cancer cell invasion. Sci Rep (2016) 0.75
Infectio: a Generic Framework for Computational Simulation of Virus Transmission between Cells. mSphere (2016) 0.75
A role for the small GTPase Rac1 in vaccinia actin-based motility. Small GTPases (2015) 0.75
Correction: Stoichiometry of Nck-dependent actin polymerization in living cells. J Cell Biol (2015) 0.75
UNC-45A Is a Nonmuscle Myosin IIA Chaperone Required for NK Cell Cytotoxicity via Control of Lytic Granule Secretion. J Immunol (2015) 0.75
The Shigella Virulence Factor IcsA Relieves N-WASP Autoinhibition by Displacing the VCA Domain. J Biol Chem (2016) 0.75
WASP family proteins, more than Arp2/3 activators. Biochem Soc Trans (2016) 0.75
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