Published in Cell Microbiol on March 16, 2012
Recent advances in understanding enteric pathogenic Escherichia coli. Clin Microbiol Rev (2013) 2.43
Intimate host attachment: enteropathogenic and enterohaemorrhagic Escherichia coli. Cell Microbiol (2013) 1.12
EspC promotes epithelial cell detachment by enteropathogenic Escherichia coli via sequential cleavages of a cytoskeletal protein and then focal adhesion proteins. Infect Immun (2014) 0.91
Actin cytoskeleton manipulation by effector proteins secreted by diarrheagenic Escherichia coli pathotypes. Biomed Res Int (2012) 0.85
Effector triggered manipulation of host immune response elicited by different pathotypes of Escherichia coli. Virulence (2014) 0.80
Local and Long-Distance Calling: Conversations between the Gut Microbiota and Intra- and Extra-Gastrointestinal Tract Infections. Front Cell Infect Microbiol (2016) 0.80
Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector. Cell Adh Migr (2014) 0.76
Vinculin Interacts with the Chlamydia Effector TarP Via a Tripartite Vinculin Binding Domain to Mediate Actin Recruitment and Assembly at the Plasma Membrane. Front Cell Infect Microbiol (2015) 0.75
Expression Regulation of Polycistronic lee3 Genes of Enterohaemorrhagic Escherichia coli. PLoS One (2016) 0.75
Tir Is Essential for the Recruitment of Tks5 to Enteropathogenic Escherichia coli Pedestals. PLoS One (2015) 0.75
The basolateral vesicle sorting machinery and basolateral proteins are recruited to the site of enteropathogenic E. coli microcolony growth at the apical membrane. PLoS One (2017) 0.75
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A (2000) 96.90
Diarrheagenic Escherichia coli. Clin Microbiol Rev (1998) 30.09
GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol (2005) 10.44
Escherichia coli strains that cause diarrhoea but do not produce heat-labile or heat-stable enterotoxins and are non-invasive. Lancet (1978) 10.29
Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells. Cell (1997) 9.60
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell (1999) 8.07
Adhesion of enteropathogenic Escherichia coli to human intestinal enterocytes and cultured human intestinal mucosa. Infect Immun (1987) 6.77
Molecular and functional characterization of the Salmonella invasion gene invA: homology of InvA to members of a new protein family. J Bacteriol (1992) 6.08
The WASP-WAVE protein network: connecting the membrane to the cytoskeleton. Nat Rev Mol Cell Biol (2007) 6.00
The eae gene of enteropathogenic Escherichia coli encodes a 94-kilodalton membrane protein, the expression of which is influenced by the EAF plasmid. Infect Immun (1991) 5.75
Citrobacter rodentium of mice and man. Cell Microbiol (2005) 4.76
EspFU is a translocated EHEC effector that interacts with Tir and N-WASP and promotes Nck-independent actin assembly. Dev Cell (2004) 3.36
TccP is an enterohaemorrhagic Escherichia coli O157:H7 type III effector protein that couples Tir to the actin-cytoskeleton. Cell Microbiol (2004) 2.91
Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway. J Biol Chem (2001) 2.85
Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP. Nat Cell Biol (2001) 2.75
A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization. Nat Cell Biol (2000) 2.72
WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells. Proc Natl Acad Sci U S A (1997) 2.54
Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells. EMBO Rep (2001) 2.48
Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells. Nat Cell Biol (2001) 2.41
Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements. Mol Microbiol (2011) 2.33
Physical mechanisms of signal integration by WASP family proteins. Annu Rev Biochem (2010) 2.18
Phosphorylation of tyrosine 474 of the enteropathogenic Escherichia coli (EPEC) Tir receptor molecule is essential for actin nucleating activity and is preceded by additional host modifications. Mol Microbiol (1999) 2.15
EspH, a new cytoskeleton-modulating effector of enterohaemorrhagic and enteropathogenic Escherichia coli. Mol Microbiol (2003) 2.04
IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation. Cell Host Microbe (2009) 2.01
Phosphorylation of the enteropathogenic E. coli receptor by the Src-family kinase c-Fyn triggers actin pedestal formation. Nat Cell Biol (2004) 1.99
Binding of intimin from enteropathogenic Escherichia coli to Tir and to host cells. Mol Microbiol (1999) 1.95
Attaching effacing Escherichia coli and paradigms of Tir-triggered actin polymerization: getting off the pedestal. Cell Microbiol (2007) 1.92
The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network. Mol Cell Biol (2003) 1.86
Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome. Cell (2002) 1.70
EFC/F-BAR proteins and the N-WASP-WIP complex induce membrane curvature-dependent actin polymerization. EMBO J (2008) 1.62
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function. PLoS Pathog (2009) 1.61
The pathogen protein EspF(U) hijacks actin polymerization using mimicry and multivalency. Nature (2008) 1.48
Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation. Proc Natl Acad Sci U S A (2009) 1.46
Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF(U). Nature (2008) 1.43
NleH effectors interact with Bax inhibitor-1 to block apoptosis during enteropathogenic Escherichia coli infection. Proc Natl Acad Sci U S A (2010) 1.43
Characterisation of IRTKS, a novel IRSp53/MIM family actin regulator with distinct filament bundling properties. J Cell Sci (2007) 1.42
The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck. J Biol Chem (1998) 1.39
Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly. J Cell Biol (2004) 1.39
Enteropathogenic Escherichia coli use redundant tyrosine kinases to form actin pedestals. Mol Biol Cell (2004) 1.32
Nck-independent actin assembly is mediated by two phosphorylated tyrosines within enteropathogenic Escherichia coli Tir. Mol Microbiol (2005) 1.32
Characterization of TccP-mediated N-WASP activation during enterohaemorrhagic Escherichia coli infection. Cell Microbiol (2006) 1.25
CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family. Proc Natl Acad Sci U S A (2001) 1.24
Interaction of enteropathogenic Escherichia coli with human intestinal mucosa: role of effector proteins in brush border remodeling and formation of attaching and effacing lesions. Infect Immun (2005) 1.20
The locus of enterocyte effacement-encoded effector proteins all promote enterohemorrhagic Escherichia coli pathogenicity in infant rabbits. Infect Immun (2005) 1.19
The mechanisms used by enteropathogenic Escherichia coli to control filopodia dynamics. Cell Microbiol (2008) 1.18
Subversion of actin dynamics by EspM effectors of attaching and effacing bacterial pathogens. Cell Microbiol (2008) 1.14
A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosis. EMBO J (2010) 1.14
Enterohaemorrhagic and enteropathogenic Escherichia coli Tir proteins trigger a common Nck-independent actin assembly pathway. Cell Microbiol (2007) 1.11
EspT triggers formation of lamellipodia and membrane ruffles through activation of Rac-1 and Cdc42. Cell Microbiol (2008) 1.06
Enteropathogenic Escherichia coli Tir is an SH2/3 ligand that recruits and activates tyrosine kinases required for pedestal formation. Mol Microbiol (2007) 1.06
Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo. Mol Microbiol (2009) 1.01
Multiple WASP-interacting protein recognition motifs are required for a functional interaction with N-WASP. J Biol Chem (2007) 1.00
WICH, a novel verprolin homology domain-containing protein that functions cooperatively with N-WASP in actin-microspike formation. Biochem Biophys Res Commun (2002) 1.00
The WASP-binding protein WIRE has a role in the regulation of the actin filament system downstream of the platelet-derived growth factor receptor. Exp Cell Res (2002) 0.89
A novel category of enteropathogenic Escherichia coli simultaneously utilizes the Nck and TccP pathways to induce actin remodelling. Cell Microbiol (2006) 0.87
CR16, a novel proline-rich protein expressed in rat brain neurons, binds to SH3 domains and is a MAP kinase substrate. J Mol Neurosci (1996) 0.84
Enteropathogenic and enterohemorrhagic Escherichia coli type III secretion effector EspV induces radical morphological changes in eukaryotic cells. Infect Immun (2010) 0.82
Citrobacter rodentium of mice and man. Cell Microbiol (2005) 4.76
An extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their dissemination. Proc Natl Acad Sci U S A (2006) 3.89
Enteropathogenic and enterohemorrhagic Escherichia coli infections: translocation, translocation, translocation. Infect Immun (2005) 3.44
Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69. J Bacteriol (2008) 3.10
TccP is an enterohaemorrhagic Escherichia coli O157:H7 type III effector protein that couples Tir to the actin-cytoskeleton. Cell Microbiol (2004) 2.91
Enteropathogenic Escherichia coli: unravelling pathogenesis. FEMS Microbiol Rev (2005) 2.49
Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements. Mol Microbiol (2011) 2.33
Central role for B lymphocytes and CD4+ T cells in immunity to infection by the attaching and effacing pathogen Citrobacter rodentium. Infect Immun (2003) 2.22
Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium. Cell Microbiol (2004) 2.18
Fresh fruit and vegetables as vehicles for the transmission of human pathogens. Environ Microbiol (2010) 2.10
In vivo bioluminescence imaging of the murine pathogen Citrobacter rodentium. Infect Immun (2006) 2.07
The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65. PLoS Pathog (2010) 2.03
Essential role of the type III secretion system effector NleB in colonization of mice by Citrobacter rodentium. Infect Immun (2006) 2.01
Identification of a novel Citrobacter rodentium type III secreted protein, EspI, and roles of this and other secreted proteins in infection. Infect Immun (2004) 1.95
Enteropathogenic Escherichia coli (EPEC) adhesion to intestinal epithelial cells: role of bundle-forming pili (BFP), EspA filaments and intimin. Microbiology (2004) 1.91
Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. PLoS One (2010) 1.90
The Citrobacter rodentium genome sequence reveals convergent evolution with human pathogenic Escherichia coli. J Bacteriol (2009) 1.85
Modelling infectious disease - time to think outside the box? Nat Rev Microbiol (2006) 1.82
Impaired resistance and enhanced pathology during infection with a noninvasive, attaching-effacing enteric bacterial pathogen, Citrobacter rodentium, in mice lacking IL-12 or IFN-gamma. J Immunol (2002) 1.80
Identification of a novel type IV pilus gene cluster required for gastrointestinal colonization of Citrobacter rodentium. Mol Microbiol (2003) 1.76
A type III effector antagonizes death receptor signalling during bacterial gut infection. Nature (2013) 1.65
Legionella pneumophila strain 130b possesses a unique combination of type IV secretion systems and novel Dot/Icm secretion system effector proteins. J Bacteriol (2010) 1.64
Exploring weathering: effects of lifelong economic environment and maternal age on low birth weight, small for gestational age, and preterm birth in African-American and white women. Am J Epidemiol (2010) 1.55
Subversion of actin dynamics by EPEC and EHEC. Curr Opin Microbiol (2006) 1.53
Salmonella bongori provides insights into the evolution of the Salmonellae. PLoS Pathog (2011) 1.52
Regulators encoded in the Escherichia coli type III secretion system 2 gene cluster influence expression of genes within the locus for enterocyte effacement in enterohemorrhagic E. coli O157:H7. Infect Immun (2004) 1.49
The enteropathogenic Escherichia coli type III secretion system effector Map binds EBP50/NHERF1: implication for cell signalling and diarrhoea. Mol Microbiol (2006) 1.47
Efa1 influences colonization of the bovine intestine by shiga toxin-producing Escherichia coli serotypes O5 and O111. Infect Immun (2002) 1.46
NleH effectors interact with Bax inhibitor-1 to block apoptosis during enteropathogenic Escherichia coli infection. Proc Natl Acad Sci U S A (2010) 1.43
The effects of racial density and income incongruity on pregnancy outcomes. Soc Sci Med (2004) 1.40
Interaction of Shiga toxin from Escherichia coli with human intestinal epithelial cell lines and explants: Stx2 induces epithelial damage in organ culture. Cell Microbiol (2004) 1.36
Yeast two-hybrid system survey of interactions between LEE-encoded proteins of enteropathogenic Escherichia coli. Microbiology (2003) 1.34
Enteropathogenic Escherichia coli type III effectors EspG and EspG2 disrupt the microtubule network of intestinal epithelial cells. Infect Immun (2005) 1.34
A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation. Mol Microbiol (2011) 1.33
EspJ is a prophage-carried type III effector protein of attaching and effacing pathogens that modulates infection dynamics. Infect Immun (2005) 1.32
Characterization of two non-locus of enterocyte effacement-encoded type III-translocated effectors, NleC and NleD, in attaching and effacing pathogens. Infect Immun (2005) 1.29
Coiled-coil proteins associated with type III secretion systems: a versatile domain revisited. Mol Microbiol (2002) 1.27
Structure of the bundle-forming pilus from enteropathogenic Escherichia coli. J Biol Chem (2005) 1.27
EspJ of enteropathogenic and enterohaemorrhagic Escherichia coli inhibits opsono-phagocytosis. Cell Microbiol (2008) 1.26
Emergence of a 'hyperinfectious' bacterial state after passage of Citrobacter rodentium through the host gastrointestinal tract. Cell Microbiol (2005) 1.25
Characterization of TccP-mediated N-WASP activation during enterohaemorrhagic Escherichia coli infection. Cell Microbiol (2006) 1.25
Long polar fimbriae and tissue tropism in Escherichia coli O157:H7. Microbes Infect (2006) 1.20
Interaction of enteropathogenic Escherichia coli with human intestinal mucosa: role of effector proteins in brush border remodeling and formation of attaching and effacing lesions. Infect Immun (2005) 1.20
Subversion of trafficking, apoptosis, and innate immunity by type III secretion system effectors. Trends Microbiol (2013) 1.18
Tir phosphorylation and Nck/N-WASP recruitment by enteropathogenic and enterohaemorrhagic Escherichia coli during ex vivo colonization of human intestinal mucosa is different to cell culture models. Cell Microbiol (2007) 1.18
The mechanisms used by enteropathogenic Escherichia coli to control filopodia dynamics. Cell Microbiol (2008) 1.18
SepL, a protein required for enteropathogenic Escherichia coli type III translocation, interacts with secretion component SepD. Mol Microbiol (2004) 1.17
Inhibition of NF-κB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. J Immunol (2010) 1.17
Distribution of tccP in clinical enterohemorrhagic and enteropathogenic Escherichia coli isolates. J Clin Microbiol (2005) 1.17
Distribution of espI among clinical enterohaemorrhagic and enteropathogenic Escherichia coli isolates. J Med Microbiol (2004) 1.16
CesT is a bivalent enteropathogenic Escherichia coli chaperone required for translocation of both Tir and Map. Mol Microbiol (2003) 1.16
Involvement of the intermediate filament protein cytokeratin-18 in actin pedestal formation during EPEC infection. EMBO Rep (2004) 1.16
Subversion of actin dynamics by EspM effectors of attaching and effacing bacterial pathogens. Cell Microbiol (2008) 1.14
Intimate host attachment: enteropathogenic and enterohaemorrhagic Escherichia coli. Cell Microbiol (2013) 1.12
RegA, an AraC-like protein, is a global transcriptional regulator that controls virulence gene expression in Citrobacter rodentium. Infect Immun (2008) 1.11
Host defences to Citrobacter rodentium. Int J Med Microbiol (2003) 1.10
3D structure of EspA filaments from enteropathogenic Escherichia coli. Mol Microbiol (2003) 1.10
Comparison of colonization dynamics and pathology of mice infected with enteropathogenic Escherichia coli, enterohaemorrhagic E. coli and Citrobacter rodentium. FEMS Microbiol Lett (2006) 1.09
Polarity of enteropathogenic Escherichia coli EspA filament assembly and protein secretion. J Bacteriol (2005) 1.09
TccP2 of O157:H7 and non-O157 enterohemorrhagic Escherichia coli (EHEC): challenging the dogma of EHEC-induced actin polymerization. Infect Immun (2006) 1.09
Transcriptome of enterohemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes. Infect Immun (2004) 1.08
Bacterial guanine nucleotide exchange factors SopE-like and WxxxE effectors. Infect Immun (2010) 1.07
Infection strategies of enteric pathogenic Escherichia coli. Gut Microbes (2012) 1.06
EspT triggers formation of lamellipodia and membrane ruffles through activation of Rac-1 and Cdc42. Cell Microbiol (2008) 1.06
CesAB is an enteropathogenic Escherichia coli chaperone for the type-III translocator proteins EspA and EspB. Microbiology (2003) 1.05
Distribution of the saa gene in strains of Shiga toxin-producing Escherichia coli of human and bovine origins. J Clin Microbiol (2003) 1.05
Role of intimin-tir interactions and the tir-cytoskeleton coupling protein in the colonization of calves and lambs by Escherichia coli O157:H7. Infect Immun (2006) 1.05
Citrobacter rodentium is an unstable pathogen showing evidence of significant genomic flux. PLoS Pathog (2011) 1.05
Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice. J Immunol (2004) 1.04
Adherence of enterohemorrhagic Escherichia coli O157, O26, and O111 strains to bovine intestinal explants ex vivo. Appl Environ Microbiol (2007) 1.04
EspF of enteropathogenic Escherichia coli binds sorting nexin 9. J Bacteriol (2006) 1.04
Interaction of Salmonella enterica with basil and other salad leaves. ISME J (2008) 1.04
Identification and characterization of EspK, a type III secreted effector protein of enterohaemorrhagic Escherichia coli O157:H7. FEMS Microbiol Lett (2006) 1.03
Human intestinal tissue tropism in Escherichia coli O157 : H7--initial colonization of terminal ileum and Peyer's patches and minimal colonic adhesion ex vivo. Microbiology (2007) 1.02
Role of NleH, a type III secreted effector from attaching and effacing pathogens, in colonization of the bovine, ovine, and murine gut. Infect Immun (2008) 1.02
Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo. Mol Microbiol (2009) 1.01
Salmonella enterica serovar Typhimurium interaction with dendritic cells: impact of the sifA gene. Cell Microbiol (2004) 1.01
The p50 subunit of NF-kappaB is critical for in vivo clearance of the noninvasive enteric pathogen Citrobacter rodentium. Infect Immun (2008) 1.00
CesD2 of enteropathogenic Escherichia coli is a second chaperone for the type III secretion translocator protein EspD. Infect Immun (2003) 0.99
Enteropathogenic Escherichia coli O125:H6 triggers attaching and effacing lesions on human intestinal biopsy specimens independently of Nck and TccP/TccP2. Infect Immun (2007) 0.99
Legionella pneumophila pathogenesis in the Galleria mellonella infection model. Infect Immun (2012) 0.99
Genomic comparison of the O-antigen biosynthesis gene clusters of Escherichia coli O55 strains belonging to three distinct lineages. Microbiology (2008) 0.98
Evaluation of a comprehensive slip, trip and fall prevention programme for hospital employees. Ergonomics (2008) 0.98
Structural and functional studies of the enteropathogenic Escherichia coli type III needle complex protein EscJ. Mol Microbiol (2005) 0.98
A C-terminal class I PDZ binding motif of EspI/NleA modulates the virulence of attaching and effacing Escherichia coli and Citrobacter rodentium. Cell Microbiol (2007) 0.98
Enterohemorrhagic Escherichia coli exploits EspA filaments for attachment to salad leaves. Appl Environ Microbiol (2008) 0.97
The T3SS effector EspT defines a new category of invasive enteropathogenic E. coli (EPEC) which form intracellular actin pedestals. PLoS Pathog (2009) 0.97